Contribution of halophilic nucleoside diphosphate kinase sequence to the heat stability of chimeric molecule.

abstract：:Peptides with more than one biological activity are many a times multifunctional peptides. Two peptides with multifunctional properties from alpha (S2)-casein were stabilized in presence of cosolvents for their biological activities like ACE inhibition activity and antioxidant activity. These bioactive peptides in cos...

journal_title：Protein and peptide letters

authors： Srinivas S,Prakash V

更新日期：2008-01-01 00:00:00

abstract：:Most proteinaceous pores are characterized as ionic channels. However, some are also involved in protein translocation through phospholipidic membranes. This concept has evolved slowly in cell biology and in biophysics, requiring the development of adapted electrical and biochemical methods. Protein translocation in m...

journal_title：Protein and peptide letters

authors： Henry JP

更新日期：2014-03-01 00:00:00

abstract：:Natural, synthetic and analogues of peptides have shown prospects for application in cancer chemotherapy. Notably, some food protein-derived peptides are known to possess anticancer activities in cultured cancer cells, and also in animal cancer models via different mechanisms including induction of apoptosis, cell cyc...

journal_title：Protein and peptide letters

authors： Rajendran SR,Ejike CE,Gong M,Hannah W,Udenigwe CC

更新日期：2017-01-01 00:00:00

abstract：:A computer-aided docking study was carried out to quickly clarify the binding structure of the ligand-receptor complex between bisphenol A (BPA), a well-known endocrine disruptor, and estrogen-related receptor gamma (ERRgamma). The resulting complex indicated that BPA binds to the ligand-binding pocket of ERRgamma wit...

journal_title：Protein and peptide letters

authors： Nose T,Shimohigashi Y

更新日期：2008-01-01 00:00:00

abstract：:Bromelain inhibitor, "bromein", is a proteinase-inhibitor specific to the cysteine proteinase bromelain from pineapple stem. In the stem, eight bromein isoforms are known to exist, and each isoform has a short peptide (light chain) and a long one (heavy chain) with five disulfide bonds. The three-dimensional structure...

journal_title：Protein and peptide letters

authors： Hatano KI,Takahashi K,Tanokura M

更新日期：2018-01-01 00:00:00

abstract：:The catalytic regions of Protein Kinases are known to have similarity in primary chains. However, it is not known whether there is a signature profile specific to a particular catalytic region? Whether the signature profile, if any, is unique to a protein kinases family in a particular species or in a group of species...

journal_title：Protein and peptide letters

authors： Joshi RR,Manda C

更新日期：2007-01-01 00:00:00

abstract：:Self-Interacting Proteins (SIPs), whose two or more copies can interact with each other, have significant roles in cellular functions and evolution of Protein Interaction Networks (PINs). Knowing whether a protein can act on itself is important to understand its functions. Previous studies on SIPs have focused on thei...

journal_title：Protein and peptide letters

authors： Qu J,Zhao Y,Zhang L,Cai SB,Ming Z,Wang CC

更新日期：2020-01-01 00:00:00

abstract：:Apelin, an endogenous ligand of the G-protein-coupled receptor APJ, is a novel myokine and may play a key role in regulating energy metabolism. The purpose of the present study was to investigate the effects of hypoxic exposure, exercise, and hypoxic exercise training on the expression of apelin and APJ in skeletal mu...

journal_title：Protein and peptide letters

authors： Ji W,Gong L,Wang J,He H,Zhang Y

更新日期：2017-01-01 00:00:00

abstract：:We report that the plant oncoprotein RolA from Agrobacterium rhizogenes acts to stabilize beta-glucoronidase (Gus) when the two proteins are expressed as a fusion protein in transformed tobacco. The observed 50-fold increase of Gus activity was shown to be related to protein accumulation, with no significant changes i...

journal_title：Protein and peptide letters

authors： Barros LM,Curtis RH,Viana AA,Campos L,Carneiro M

更新日期：2003-06-01 00:00:00

abstract：:C-terminal peptide alpha-thioesters are valuable intermediates in the synthesis/semisynthesis of proteins by native chemical ligation. They are prepared either by solid-phase peptide synthesis (SPPS) or biosynthetically by protein splicing techniques. The present paper reviews the different methods available for the c...

journal_title：Protein and peptide letters

authors： Camarero JA,Mitchell AR

更新日期：2005-11-01 00:00:00

abstract：:In this paper, a 3D map of protein fold space was produced using Dali structure alignment and nonmetric multidimensional scaling. The fold space comprises four radial clusters, which correspond to the four classes of SCOP. The overall structure of the protein fold space is largely determined by three factors: secondar...

journal_title：Protein and peptide letters

authors： Xu Q

更新日期：2005-07-01 00:00:00

abstract：:Solid state nuclear magnetic resonance (NMR) has developed into one of the most informative and direct experimental approaches to the characterization of the molecular structures of amyloid fibrils, including those associated with Alzheimer's disease. In this article, essential aspects of solid state NMR methods are d...

journal_title：Protein and peptide letters

authors： Tycko R

更新日期：2006-01-01 00:00:00

abstract：:The human gut microbial ecosystem (HGME) exerts an important influence on the human health. In recent researches, meta-genomics provided deep insights into the HGME in terms of gene contents, metabolic processes and genome constitutions of meta-genome. Here we present a novel methodology to investigate the HGME on the...

journal_title：Protein and peptide letters

authors： Ji Y,Shi Y,Wang C,Dai J,Li Y

更新日期：2013-03-01 00:00:00

abstract：:In the development of cell-hybrid biomaterials, the functional activity of cells depends on the selective binding of cells to artificial ligands on the biomaterials. The extracellular matrix (ECM) is the most important ligand for cell activity. ECM is known to contain collagen, one of whose constituents is gelatin. Al...

journal_title：Protein and peptide letters

authors： Miyamoto K,Chinzei H,Komai T

更新日期：2002-12-01 00:00:00

abstract：:The physiological stability curve--a plot of the free energy of unfolding versus temperature--is calculated for hen egg white lysozyme from a combination of extrapolated unfolding thermodynamic data from reversible conditions and isothermal titrations with guanidine hydrochloride. The shape of the curve suggests the e...

journal_title：Protein and peptide letters

authors： Younvanich SS,Britt BM

更新日期：2006-01-01 00:00:00

abstract：:Saturation Transfer Difference NMR (STD NMR) is used for the detection of the binding constant of the decapeptide RRRDDDSDDD with CK2α, the catalytic subunit of the proteinkinase CK2. For this work a valid irradiation frequency of the CK2α had to be found ensuring that no peptide resonance is affected by the irradiati...

journal_title：Protein and peptide letters

authors： Raüber C,Berger S

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Laminin, a member of the Extracellular Matrix (ECM), is a glycoprotein that is used as a factor that affects cell adhesion, proliferation, survival, and differentiation. Of these, five globular domains (LG domains) of the alpha chain play an important role in influencing the cell by binding to the integrin. ...

journal_title：Protein and peptide letters

authors： Kim JE,Seo HJ,Lee S,Jang JH

更新日期：2019-01-01 00:00:00

abstract：:It is important to understand the conformational biases that are present in unfolded states to understand protein folding. In this context, it is surprising that even a short tripeptide like AFA samples folded/ordered conformation as demonstrated recently by NMR experiments of the peptide in aqueous solution at 280 K....

journal_title：Protein and peptide letters

authors： Patel S,Taimni R,Sasidhar YU

更新日期：2007-01-01 00:00:00

abstract：:An efficient preparation of Periplaneta americana nymphae allergen, Cr PI (54 kDa) is described. It was expressed as a GST-tag fusion protein in Escherichia coli, strain BL21 (DE3). Expression of recombinant Cr PI (rCr PI), denaturation/renaturation of the inclusion bodies and the effects of protein and L-arginine con...

journal_title：Protein and peptide letters

authors： Wu HQ,Liu ZG,Ran PX,Zhou ZW,Gao B

更新日期：2007-01-01 00:00:00

abstract：:Allergy prevalence has increased worldwide over the last 25 years along with industrialization and westernized lifestyles. Indoor allergens are primarily responsible for the sensitization and development of atopic diseases. The main indoor allergens are known to be derived from various arthropods which account for up ...

journal_title：Protein and peptide letters

authors： Jeong KY,Hong CS,Yong TS

更新日期：2007-01-01 00:00:00

abstract：:Zwitterionic dipeptides have recently been shown to exist in water mainly as nine conformational forms with specific combinations of backbone Psi, omega and Phi torsions, which allows conformer-specific molecular recognition of peptide ligands by proteins. Here, we show that pairs of virtual backbone torsions can also...

journal_title：Protein and peptide letters

authors： Gupta S,Grail BM,Payne JW

更新日期：2002-04-01 00:00:00

abstract：:The immunoglobulin fold (Ig-fold) is a widespread structural motif that is detected in a variety of proteins involved in diversified biological processes. The Ig-fold contains 70-110 residues that are assembled in a characteristic sandwich-like structure formed by two facing β-sheets each made of antiparallel β-strand...

journal_title：Protein and peptide letters

authors： Berisio R,Ciccarelli L,Squeglia F,De Simone A,Vitagliano L

更新日期：2012-10-01 00:00:00

abstract：:Antimicrobial peptides (AMPs) constitute an important alternative in the search for new treatments against pathogens. We analyzed the sequence variability in cytokine and chemokine proteins to investigate whether these molecules contain a sequence useful in the development of new AMPs. Cluster analysis allowed the ide...

journal_title：Protein and peptide letters

authors： Robles-Gomez EE,Flores-Villegas MC,Gonzalez-Manjarrez A,Soriano-Garcia M

更新日期：2013-05-01 00:00:00

abstract：:A significant association between increased level of blood homocysteine (hyperhomocysteinimia) and various eye pathological disorders including cataract has been reported. This metabolic byproduct is converted into a highly reactive cyclic thioester compound, homocysteine thiolactone (HCTL), which can potentially reac...

journal_title：Protein and peptide letters

authors： Hajjari S,Masoudi R,Javadi S,Hemmateenejad B,Yousefi R

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Bursa of Fabricius plays the vital functions on B cell development and antibody production in poultry. The bursal-derived peptide plays the essential roles on avian immature B cell development. OBJECTIVES:Here we explored the functions of the recently reported bursal nonapeptide (BP9) on the antibody produc...

journal_title：Protein and peptide letters

authors： Zheng Y,Zong MM,Chen BY,Zhou XH,Liu ZN,Zhou GF,Chen PY,Feng XL

更新日期：2019-01-01 00:00:00

abstract：:We investigated the in vitro antibiotic activity of the 19-amino acid antimicrobial peptide HP (2-20), derived from the N-terminus of Helicobacter pylori Ribosomal Protein L1 (RPL1), against antibiotic susceptible and resistant pathogens from a patient with gallstones. HP (2-20) was active against antibiotic-susceptib...

journal_title：Protein and peptide letters

authors： Park Y,Hahm JS,Hahm KS

更新日期：2006-01-01 00:00:00

abstract：:This work describes the investigations of electrochemical interactions of naphthalene acetic acid (NAA) with stabilized lipid films supported on a methacrylate polymer on a glass fiber filter with incorporated auxin-binding protein 1 receptor for the development of a biosensor for the rapid detection of this compound ...

journal_title：Protein and peptide letters

authors： Nikolelis DP,Ntanos N,Nikoleli GP,Tampouris K

更新日期：2008-01-01 00:00:00

abstract：:Hepatitis C virus (HCV) triggers coordinated innate and adaptive response in host cell. HCV genome and proteins of the replicating virus are recognized as non-self-antigens by host cell to activate Toll Like Receptors (TLRs). Activated TLRs ultimately express cytokines, which can clear virus either by activating inter...

journal_title：Protein and peptide letters

authors： Farooqi ZU,Tareen SH,Ahmed J,Zaidi NU

更新日期：2016-01-01 00:00:00

abstract：:Heparin is naturally occurring polysaccharides which interacts with seminal plasma proteins and regulate multiple steps in fertilization process. Qualitative and quantitative information regarding the affinity for heparin-seminal plasma proteins interactions is not generally well documented and there are no reports of...

journal_title：Protein and peptide letters

authors： Kumar V,Yadav VK,Hassan MI,Singh AK,Dey S,Singh S,Singh TP,Yadav S

更新日期：2012-08-01 00:00:00

abstract：:In 2008 cancer was identified by the World Health Organization (WHO) as one of four threats to human health and development. Since the early published reports of the first chemotherapeutic, mustine, in 1946, the anti-cancer drug and development industry has grown into a multi-billion dollar business enterprise. Worldw...

journal_title：Protein and peptide letters

authors： Li Q,Yi L,Marek P

更新日期：2014-01-01 00:00:00