Coordinating the events of the meiotic prophase.

Abstract:

:Meiosis is a specialized type of cell division leading to the production of gametes. During meiotic prophase I, homologous chromosomes interact with each other and form bivalents (pairs of homologous chromosomes). Three major meiotic processes--chromosome pairing, synapsis and recombination--are involved in the formation of bivalents. Many recent reports have uncovered complex networks of interactions between these processes. Chromosome pairing is largely dependent on the initiation and progression of recombination in fungi, mammals and plants, but not in Caenorhabditis elegans or Drosophila. Synapsis and recombination are also tightly linked. Understanding the coordination between chromosome pairing, synapsis and recombination lends insight into many poorly explained aspects of meiosis, such as the nature of chromosome homology recognition.

journal_name

Trends Cell Biol

journal_title

Trends in cell biology

authors

Pawlowski WP,Cande WZ

doi

10.1016/j.tcb.2005.10.005

subject

Has Abstract

pub_date

2005-12-01 00:00:00

pages

674-81

issue

12

eissn

0962-8924

issn

1879-3088

pii

S0962-8924(05)00249-7

journal_volume

15

pub_type

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