Scattering coefficient determination in turbid media with backscattered polarized light.

abstract：:The area of in vivo sensing using optical fibers commonly uses materials such as silica and polymethyl methacrylate, both of which possess much higher modulus than human tissue. The mechanical mismatch between materials and living tissue has been seen to cause higher levels of glial encapsulation, scarring, and inflam...

journal_title：Journal of biomedical optics

authors： McMillan S,Rader C,Jorfi M,Pickrell G,Foster EJ

更新日期：2017-02-01 00:00:00

abstract：:The properties of polarized light emerging from turbid media in the exact backscattering direction are studied by modulating the incident light polarization state and isolating the synchronous signal with lock-in amplifier detection. The results are reported for polystyrene microsphere suspensions in distilled water, ...

journal_title：Journal of biomedical optics

authors： Studinski RC,Vitkin IA

更新日期：2000-07-01 00:00:00

abstract：:Previous studies have shown the ability of many lymphatic vessels to contract phasically to pump lymph. Every lymphangion can act like a heart with pacemaker sites that initiate the phasic contractions. The contractile wave propagates along the vessel to synchronize the contraction. However, determining the location o...

journal_title：Journal of biomedical optics

authors： Akl TJ,Nepiyushchikh ZV,Gashev AA,Zawieja DC,Cot GL

更新日期：2011-02-01 00:00:00

abstract：SIGNIFICANCE:In breast-preserving tumor surgery, the inspection of the excised tissue boundaries for tumor residue is too slow to provide feedback during the surgery. The discovery of positive margins requires a new surgery which is difficult and associated with low success. If the re-excision could be done immediately...

journal_title：Journal of biomedical optics

authors： Beletkaia E,Dashtbozorg B,Jansen RG,Ruers TJM,Offerhaus HL

更新日期：2020-09-01 00:00:00

abstract：:Polarization interferometry (PI) techniques, which are able to improve surface plasmon resonance (SPR) sensing performance and reduce restrictions on allowable parameters of SPR-supporting metal films, have been experimentally realized only in SPR sensors using monochromatic light as a source. Wavelength-interrogation...

journal_title：Journal of biomedical optics

authors： Liu Z,Liu L,Wang X,Shi H,Chong X,Ma S,Ji Y,Guo J,Ma H,He Y

更新日期：2012-03-01 00:00:00

abstract：:Fluorescence cystoscopy (FC) efficiently enhances the detection and improves the therapeutic management of early bladder cancer. During an FC, about 150 ml of water is needed to inflate the bladder. The water is quickly diluted by urine which can be fluorescent. If this bladder washout fluid (BWF) becomes fluorescent,...

journal_title：Journal of biomedical optics

authors： Zellweger M,Martoccia C,Mengin M,Iselin C,van den Bergh H,Wagnières G

更新日期：2015-06-01 00:00:00

abstract：:Optical technique based on diffuse reflectance measurement combined with indocyanine green (ICG) bolus tracking is extensively tested as a method for clinical assessment of brain perfusion in adults at the bedside. Methodology of multiwavelength and time-resolved detection of fluorescence light excited in the ICG is p...

journal_title：Journal of biomedical optics

authors： Gerega A,Milej D,Weigl W,Botwicz M,Zolek N,Kacprzak M,Wierzejski W,Toczylowska B,Mayzner-Zawadzka E,Maniewski R,Liebert A

更新日期：2012-08-01 00:00:00

abstract：:Dihydroartemisinin (DHA), a front-line antimalarial herbal compound, has been shown to possess promising anticancer activity with low toxicity. We have previously reported that DHA induced caspase-3-dependent apoptosis in human lung adenocarcinoma cells. However, the cellular target and molecular mechanism of DHA-indu...

journal_title：Journal of biomedical optics

authors： Lu YY,Chen TS,Wang XP,Li L

更新日期：2010-07-01 00:00:00

abstract：:Fourier transform infrared (FTIR) spectroscopic imaging has been used to probe the biochemical composition of human renal tumor tissue and adjacent normal tissue. Freshly resected renal tumor tissue from surgery was prepared as a thin cryosection and examined by FTIR spectroscopic imaging. Tissue types could be discri...

journal_title：Journal of biomedical optics

authors： Sablinskas V,Urboniene V,Ceponkus J,Laurinavicius A,Dasevicius D,Jankevicius F,Hendrixson V,Koch E,Steiner G

更新日期：2011-09-01 00:00:00

abstract：:Artificially created demineralized and remineralized carious lesions on the root and enamel of human teeth were examined by photothermal radiometry (PTR) and modulated luminescence (LUM). Fourteen extracted human teeth were used and a lesion was created on a 1 mmx4 mm rectangular window, spanning root to enamel, using...

journal_title：Journal of biomedical optics

authors： Jeon RJ,Hellen A,Matvienko A,Mandelis A,Abrams SH,Amaechi BT

更新日期：2008-05-01 00:00:00

abstract：:The effect of glucose on fluorescence of synthesized ZnCdS nanoparticles in the presence of glucose oxidase or in a mixture of glucose oxidase and peroxidase has been investigated. Behavior of fluorescence characteristics of ZnCdS nanoparticles with nonstabilized surface and coated with polymer shell is compared. It h...

journal_title：Journal of biomedical optics

authors： Kochubey VI,Volkova EK,Konyukhova JG

更新日期：2014-01-01 00:00:00

abstract：:One of the prime limiting factors of optical imaging in biological applications is the diffusion of light by tissue, which prevents focusing at depths greater than the optical diffusion limit (typically ?1??mm). To overcome this challenge, wavefront shaping techniques that use a spatial light modulator (SLM) to correc...

journal_title：Journal of biomedical optics

authors： Hemphill AS,Tay JW,Wang LV

更新日期：2016-12-01 00:00:00

abstract：:Clustering analysis (CA) and principal component analysis (PCA) were applied to dynamic Cerenkov luminescence images (dCLI). In order to investigate the performances of the proposed approaches, two distinct dynamic data sets obtained by injecting mice with (32)P-ATP and (18)F-FDG were acquired using the IVIS 200 optic...

journal_title：Journal of biomedical optics

authors： Spinelli AE,Boschi F

更新日期：2011-12-01 00:00:00

abstract：:We used two-photon laser scanning microscopy (TPLSM) to demonstrate for the first time its potential in studying relational details at the cellular level of atherogenesis in intact, viable mouse carotid arteries. Isolated and mounted arteries of ApoE-/-mice, aged 15 or 21 weeks (7 and 13 weeks on western diet), were i...

journal_title：Journal of biomedical optics

authors： Megens RT,oude Egbrink MG,Merkx M,Slaaf DW,van Zandvoort MA

更新日期：2008-07-01 00:00:00

abstract：:We have combined a confocal laser scanning head modified for TPE (two-photon excitation) microscopy with some spectroscopic modules to study single molecules and molecular aggregates. The behavior of the TPE microscope unit has been characterized by means of point spread function measurements and of the demonstration ...

journal_title：Journal of biomedical optics

authors： Diaspro A,Chirico G,Federici F,Cannone F,Beretta S,Robello M

更新日期：2001-07-01 00:00:00

abstract：:We develop a label-free optical technique to image and discriminate undifferentiated human embryonic stem cells (hESCs) from their differentiating progenies in vitro. Using intrinsic cellular fluorophores, we perform fluorescence lifetime microscopy (FLIM) and phasor analysis to obtain hESC metabolic signatures. We id...

journal_title：Journal of biomedical optics

authors： Stringari C,Sierra R,Donovan PJ,Gratton E

更新日期：2012-04-01 00:00:00

abstract：:Breast cancer is one of the most common cancers in females. To monitor chemotherapeutic efficacy for breast cancer, medical imaging systems such as x-ray mammography, computed tomography, magnetic resonance imaging, and ultrasound imaging have been used. Currently, it can take up to 3 to 6 weeks to see the tumor respo...

journal_title：Journal of biomedical optics

authors： Lee S,Jeong H,Seong M,Kim JG

更新日期：2017-12-01 00:00:00

abstract：:A side-viewing, 2.3-mm diameter oblique incidence reflectometry endoscope has been designed to obtain optical property measurements of turbid samples. Light from a single-mode fiber is relayed obliquely onto the tissue with a gradient index lens-based distal optics assembly and the resulting diffuse reflectance profil...

journal_title：Journal of biomedical optics

authors： Wall RA,Barton JK

更新日期：2014-06-01 00:00:00

abstract：:The optical activity of glucose molecules is important for diagnosing and monitoring blood glucose of diabetes. In order to accurately detect the diabetes at an early stage, there is an urgent need to develop innovative detection methods. By use of Mueller matrix decomposition (MMD), we have studied the optical activi...

journal_title：Journal of biomedical optics

authors： Sun P,Ma Y,Liu W,Yang Q,Jia Q

更新日期：2014-04-01 00:00:00

abstract：:Application of a fiber optic biosensor (FOB) to the real-time investigation of the interaction kinetics between FITC-conjugated monoclonal sheep anti-human C-reactive protein (CRP) antibody and CRP isoforms on the surface of optical fiber is described. Recently, both the native pentameric CRP (pCRP), an acute phase pr...

journal_title：Journal of biomedical optics

authors： Chou C,Hsu HY,Wu HT,Tseng KY,Chiou A,Yu CJ,Lee ZY,Chan TS

更新日期：2007-03-01 00:00:00

abstract：:Probing tissue with near-infrared radiation (NIR) simultaneously produces remitted fluorescence and Raman scattering (IE) plus Rayleigh∕Mie light scattering (EE) that noninvasively give chemical and physical information about the materials and objects within. We model tissue as a three-phase system: plasma and red blo...

journal_title：Journal of biomedical optics

authors： Chaiken J,Deng B,Goodisman J,Shaheen G,Bussjager RJ

更新日期：2011-09-01 00:00:00

abstract：:The Nikon C1 confocal laser scanning microscope is a relatively inexpensive and user-friendly instrument. We describe a straightforward method to convert the C1 for multiphoton microscopy utilizing direct coupling of a femtosecond near-infrared laser into the scan head and fiber optic transmission of emission light to...

journal_title：Journal of biomedical optics

authors： Mancuso JJ,Larson AM,Wensel TG,Saggau P

更新日期：2009-05-01 00:00:00

abstract：:We investigate and assess the utility of a simple scheme for continuous absolute blood flow monitoring based on diffuse correlation spectroscopy (DCS). The scheme calibrates DCS using venous-occlusion diffuse optical spectroscopy (VO-DOS) measurements of arm muscle tissue at a single time-point. A calibration coeffici...

journal_title：Journal of biomedical optics

authors： Li Z,Baker WB,Parthasarathy AB,Ko TS,Wang D,Schenkel S,Durduran T,Li G,Yodh AG

更新日期：2015-01-01 00:00:00

abstract：:Peripheral nerve injury in vivo promotes a regenerative growth in vitro characterized by an improved neurite regrowth. Knowledge of the conditioning injury effects on both morphology and mechanical properties of live sensory neurons could be instrumental to understand the cellular and molecular mechanisms leading to t...

journal_title：Journal of biomedical optics

authors： Benzina O,Szabo V,Lucas O,Saab MB,Cloitre T,Scamps F,Gergely C,Martin M

更新日期：2013-10-01 00:00:00

abstract：:We have developed a near-infrared (NIR) fluorescence goggle system based on the complementary metal-oxide-semiconductor active pixel sensor imaging and see-through display technologies. The fluorescence goggle system is a compact wearable intraoperative fluorescence imaging and display system that can guide surgery in...

journal_title：Journal of biomedical optics

authors： Liu Y,Njuguna R,Matthews T,Akers WJ,Sudlow GP,Mondal S,Tang R,Gruev V,Achilefu S

更新日期：2013-10-01 00:00:00

abstract：:Functional near-infrared spectroscopy (fNIRS), acquired simultaneously with electroencephalography (EEG), allows the investigation of hemodynamic brain responses to epileptic activity. Because the presumed epileptogenic focus is patient-specific, an appropriate source/detector (SD) montage has to be reconfigured for e...

journal_title：Journal of biomedical optics

authors： Machado A,Marcotte O,Lina JM,Kobayashi E,Grova C

更新日期：2014-02-01 00:00:00

abstract：:We propose an offset-sparsity decomposition method for the enhancement of a color microscopic image of a stained specimen. The method decomposes vectorized spectral images into offset terms and sparse terms. A sparse term represents an enhanced image, and an offset term represents a "shadow." The related optimization ...

journal_title：Journal of biomedical optics

authors： Kopriva I,Hadžija MP,Hadžija M,Aralica G

更新日期：2015-07-01 00:00:00

abstract：:Pilot results on the application of the finite-difference time-domain (FDTD) approach for studying the implementation of the optical immersion technique for the visualization of single and multiple gold nanoparticles in biological cells are presented. We focus on two different scenarios considering single biological c...

journal_title：Journal of biomedical optics

authors： Tanev S,Tuchin VV,Paddon P

更新日期：2006-11-01 00:00:00

abstract：:Raman spectroscopy (RS) has demonstrated great potential for in vivo cancer screening; however, the biophysical changes that occur for specific diagnoses remain unclear. We recently developed an inverse biophysical skin cancer model to address this issue. Here, we presented the first demonstration of in vivo melanoma ...

journal_title：Journal of biomedical optics

authors： Feng X,Moy AJ,Nguyen HTM,Zhang Y,Zhang J,Fox MC,Sebastian KR,Reichenberg JS,Markey MK,Tunnell JW

更新日期：2018-05-01 00:00:00

abstract：:Microscopic visualization of islets of Langerhans under normal and diabetic conditions is essential for understanding the pathophysiology of the disease. The intrinsic opacity of pancreata, however, limits optical accessibility for high-resolution light microscopy of islets in situ. Because the standard microtome-base...

journal_title：Journal of biomedical optics

authors： Fu YY,Lu CH,Lin CW,Juang JH,Enikolopov G,Sibley E,Chiang AS,Tang SC

更新日期：2010-07-01 00:00:00