Abstract:
:The properties of polarized light emerging from turbid media in the exact backscattering direction are studied by modulating the incident light polarization state and isolating the synchronous signal with lock-in amplifier detection. The results are reported for polystyrene microsphere suspensions in distilled water, with and without glucose, and for both ex vivo and in vivo biological tissues. A new theoretical formulation based on Mueller calculus is developed to describe the observed behavior of the backscattered light in terms of two sample parameters: optical rotation and depolarization. This technique proved successful in modeling both phantom and tissue samples. Results showed the presence of a significant surviving polarization fraction in the backscattering direction even in extremely dense optical phantom media, an important finding that has not been observed at other detection angles. Substantial polarized light preservation in biological tissue samples is also demonstrated for this detection geometry. This illustrates the potential of using polarized light to investigate turbid biological materials in vivo in retroreflection geometry.
journal_name
J Biomed Optjournal_title
Journal of biomedical opticsauthors
Studinski RC,Vitkin IAdoi
10.1117/1.430004subject
Has Abstractpub_date
2000-07-01 00:00:00pages
330-7issue
3eissn
1083-3668issn
1560-2281pii
S1083-3668(00)00603-1journal_volume
5pub_type
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