Spontaneous saccades under different visual conditions in the pigeon.

abstract：:In this study we have used the transgenic mouse model Tg2576 to analyze the involvement of anomalous loss of regulation of cdk5 and the stress kinases JNK and p38 in brain neuronal death as related to neurodegenerative disorders such as Alzheimer's disease. Previous studies on hippocampal cells led us to the discovery...

journal_title：Neuroreport

authors： Otth C,Mendoza-Naranjo A,Mujica L,Zambrano A,Concha II,Maccioni RB

更新日期：2003-12-19 00:00:00

abstract：:Birds are capable of dexterous sensory-motor activities such as tool use. Reaching is a crucial component of tool use and is a vision-guided behavior in primates, in which arm movement is monitored online in a stable visual frame. However, vision-guided reaching in primates is enabled by anatomical separation of the h...

journal_title：Neuroreport

authors： Kanai M,Matsui H,Watanabe S,Izawa E

更新日期：2014-09-10 00:00:00

abstract：:Blood oxygen level dependent MRI was used to test whether cocaine-stimulated mesolimbic activity varied with sexual receptivity. Rats were randomly screened for lordotic responses and were then imaged for their responses to centrally administered cocaine. We observed that female rats expressing no lordosis showed a gr...

journal_title：Neuroreport

authors： Febo M,Segarra AC,Stolberg TL,Ferris CF

更新日期：2011-01-05 00:00:00

abstract：:The aim of this study was to show that Cl(-)-dependent excitotoxicity, with its characteristic cell swelling, involves actual water influx into the intracellular compartment. Taking advantage of the Ca2+ omission paradigm of Cl(-)-dependent excitotoxicity, in the chick embryonic neural retina ex vivo, which is associa...

journal_title：Neuroreport

authors： Burgos JS,Barat A,Ramirez G

更新日期：2000-11-27 00:00:00

abstract：:Results from a computer model of a thalamic network predict that agents augmenting GABA(A)-mediated inhibition in the reticular thalamic (RE) nucleus will be antiepileptic or desynchronizing. This provides support for the hypothesis that antiepileptics like benzodiazepines may exert their effects through an isolated i...

journal_title：Neuroreport

authors： Thomas E,Lytton WW

更新日期：1998-03-09 00:00:00

abstract：:We investigated the role of kainate receptor activation in modulating the influx of Ca2+ coupled to the exocytotic release of glutamate in rat hippocampal synaptosomal fractions (P2). In whole hippocampus synaptosomes stimulation with domoic acid increased the intracellular free Ca2+ concentration ([Ca2+]i) in a dose-...

journal_title：Neuroreport

authors： Malva JO,Carvalho AP,Carvalho CM

更新日期：1996-05-17 00:00:00

abstract：:Cells overexpressing the beta-amyloid precursor protein possessing a mutation found in familial Alzheimer's disease overproduce beta-amyloid peptide (A beta). Because these findings were based on immunological identification, we have chemically characterized the peptides produced. Purified A beta fragments from the co...

journal_title：Neuroreport

authors： Dovey HF,Suomensaari-Chrysler S,Lieberburg I,Sinha S,Keim PS

更新日期：1993-08-01 00:00:00

abstract：:Amyloid plaques and neurofibrillary tangles are the major pathological hallmarks of Alzheimer's disease. Neurofibrillary tangles are composed of filaments and paired helical filaments containing polymerized hyperphosphorylated tau protein. Derlin proteins are a family of proteins that are conserved in all eukaryotes, ...

journal_title：Neuroreport

authors： Honjo Y,Ito H,Horibe T,Shimada H,Nakanishi A,Mori H,Takahashi R,Kawakami K

更新日期：2012-07-11 00:00:00

abstract：:This report describes neurogenesis in the adult human olfactory epithelium in vitro. Olfactory epithelium was collected at autopsy and by biopsy, and grown in serum-free medium. Basic fibroblast growth factor induced the differentiation of bipolar cells which were immunopositive for several neuronal proteins but not g...

journal_title：Neuroreport

authors： Murrell W,Bushell GR,Livesey J,McGrath J,MacDonald KP,Bates PR,Mackay-Sim A

更新日期：1996-04-26 00:00:00

abstract：:Lithium treatment lengthens the period of circadian rhythms in most organisms. In the present study, we tested whether lithium acts directly on the mammalian suprachiasmatic nucleus (SCN) to lengthen rhythms of individual neurons. Lithium increased the circadian period of firing rate rhythms of cultured SCN neurons in...

journal_title：Neuroreport

authors： Abe M,Herzog ED,Block GD

更新日期：2000-09-28 00:00:00

abstract：:To investigate how pheromonal information is processed in the rat accessory olfactory bulb, we optically imaged intrinsic signals to obtain high-resolution maps of activation induced by urinary stimulation. Application of volatile components in male urine mainly induced activation in the anterior accessory olfactory b...

journal_title：Neuroreport

authors： Sugai T,Yoshimura H,Kato N,Onoda N

更新日期：2006-11-06 00:00:00

abstract：:Nogo-A, a member of the reticulon family, is one of the most important myelin-associated inhibitors for axonal growth, regeneration, and plasticity in the central nervous system. RhoA has been targeted pharmacologically to promote neurite outgrowth and functional recovery in the brain and spinal cord. However, the und...

journal_title：Neuroreport

authors： Wang H,Shen J,Xiong N,Zhao H,Chen Y

更新日期：2011-10-26 00:00:00

abstract：:Automatic phrase-building processes were investigated in second-language (L2) learners of French (native German speakers). Event-related brain potentials were recorded while participants listened to syntactically or semantically correct or incorrect French sentences containing a subject-modifying relative clause. Phra...

journal_title：Neuroreport

authors： Isel F

更新日期：2007-12-03 00:00:00

abstract：:An anti-leptin polyclonal antiserum was used to detect leptin-immunoreactivity (-ir) in the central nervous system in rats. Leptin-ir was found in perikaryon and processes of neurons in the hypothalamus, including the paraventricular nucleus, and in several regions in the brainstem, including the nucleus of the solita...

journal_title：Neuroreport

authors： Li HY,Wang LL,Yeh RS

更新日期：1999-02-05 00:00:00

abstract：:This study examined the long-term effects of the antidepressant escitalopram on rat serotonin (5-HT) neuronal activity and hippocampal neuroplasticity. In the dorsal raphe nucleus, a 2-week treatment with escitalopram (10 mg/kg/day, subcutaneous) did not modify the firing activity of 5-HT neurons, whereas a cotreatmen...

journal_title：Neuroreport

authors： Mnie-Filali O,Faure C,Mansari ME,Lambás-Señas L,Bérod A,Zimmer L,Sánchez C,Haddjeri N

更新日期：2007-10-08 00:00:00

abstract：:Scanning laser-Doppler flowmetry (SLDF) combines laser-Doppler flowmetry and laser scanning to provide images of cerebral blood flow (CBF) with high spatial and temporal resolution. We investigated the contribution of single vascular elements to the local increase of CBF accompanying increased neuronal activity in hal...

journal_title：Neuroreport

authors： Akgören N,Lauritzen M

更新日期：1999-11-08 00:00:00

abstract：:Integrating information across the senses can enhance our ability to detect and classify stimuli in the environment. For example, auditory speech perception is substantially improved when the speaker's face is visible. In an fMRI study designed to investigate the neural mechanisms underlying these crossmodal behaviour...

journal_title：Neuroreport

authors： Calvert GA,Brammer MJ,Bullmore ET,Campbell R,Iversen SD,David AS

更新日期：1999-08-20 00:00:00

abstract：:This study investigated whether mild birth complications (C-section birth, C-section + 15 min global anoxia) interact with stress at adulthood to modulate levels of [3H]WIN 35428 binding to dopamine transporters (DAT) in rat brain. Without stress, adult C-sectioned rats showed increased DAT binding in the dorsal stria...

journal_title：Neuroreport

authors： El-Khodor BF,Boksa P

更新日期：2002-02-11 00:00:00

abstract：:Dopamine plays important functional roles in the vertebrate retina. Here we show that functional D2 dopamine receptors are present on mammalian retinal Müller (glial) cells. Using an antiserum directed to two oligopeptides predicted from rat D2 receptor DNA, patchy label was demonstrated immunocytochemically on virtua...

journal_title：Neuroreport

authors： Biedermann B,Fröhlich E,Grosche J,Wagner HJ,Reichenbach A

更新日期：1995-03-07 00:00:00

abstract：:Numerous studies have shown that the cerebellum is involved in classical conditioning of specific aversive reactions. Only few studies, however, have examined the exact localization of cerebellar areas involved in the control of unconditioned reflex responses. The present study investigated cerebellar areas, which are...

journal_title：Neuroreport

authors： Maschke M,Erichsen M,Drepper J,Jentzen W,Müller SP,Kolb FP,Diener HC,Timmann D

更新日期：2002-12-03 00:00:00

abstract：:Functional neuroimaging studies of handedness have traditionally focused on exploring regionally activated discrepancies, yet little is known regarding the effect of handedness on functional connections of brain regions. Here, we reported the relationship between cerebellar functional connectivity patterns and handedn...

journal_title：Neuroreport

authors： He Y,Zang Y,Jiang T,Gong G,Xie S,Xiao J

更新日期：2006-01-23 00:00:00

abstract：:The pathogenesis of amyotrophic lateral sclerosis remains poorly understood, but microglial and astroglial activation are thought to contribute to motor neuron death. Evidence suggests that matrix metalloproteinase-9 (MMP-9) is a mediator of this deleterious effect. In this study, we evaluated the effect of MMP-9 on t...

journal_title：Neuroreport

authors： Dewil M,Schurmans C,Starckx S,Opdenakker G,Van Den Bosch L,Robberecht W

更新日期：2005-03-15 00:00:00

abstract：:Previous studies have shown that spatial memory retention is affected by the metabotropic glutamate receptor (mGluR) influencing agents (R,S)-alpha-methyl-4-carboxyphenylglycine (MCPG) and trans-azetidine-2,4-dicarboxylic acid (tADA). In the present investigation we examined whether the mGluR antagonist MCPG (20 mM an...

journal_title：Neuroreport

authors： Wetzel W,Wagner T,Reymann KG,Riedel G

更新日期：1995-11-27 00:00:00

abstract：:Self-renewing neural stem cells and progenitor cells are cell populations that generate radial glial cells and neurons through asymmetric division. Regulation of intracellular pH in stem cells with high metabolic activity is critical for both cell signaling and proliferation. We have recently found that a S0859-inhibi...

journal_title：Neuroreport

authors： Nordström T,Zhenyu G,Andersson LC,Åkerman KEO

更新日期：2020-01-08 00:00:00

abstract：:Recent studies have demonstrated a loss of cannabinoid CB1 receptors in the basal ganglia in Huntington's disease (HD), but there are no data on endocannabinoid levels in this disease. In the present study, we have addressed this question by using rats with bilateral intrastriatal injections of 3-nitropropionic acid (...

journal_title：Neuroreport

authors： Lastres-Becker I,Fezza F,Cebeira M,Bisogno T,Ramos JA,Milone A,Fernández-Ruiz J,Di Marzo V

更新日期：2001-07-20 00:00:00

abstract：:Group III metabotropic glutamate receptors (mGluR4, 6, 7, 8) are negatively coupled to adenylate cyclase and, when activated presynaptically, decrease the release of glutamate and GABA. We have used intracerebroventricular injections of agonists and antagonists believed to act selectively on these receptors to study t...

journal_title：Neuroreport

authors： Ghauri M,Chapman AG,Meldrum BS

更新日期：1996-06-17 00:00:00

abstract：:We recorded event-related potentials (ERPs) in 2-month-old infants in two different states of alertness: awake and asleep. Syllables varying in vowel duration (long vs short) were presented in an oddball paradigm, known to elicit a mismatch brain response. ERPs of both groups showed a mismatch response reflected in a ...

journal_title：Neuroreport

authors： Friederici AD,Friedrich M,Weber C

更新日期：2002-07-19 00:00:00

abstract：:We have previously shown that hippocampal long-term potentiation (LTP), one form of synaptic plasticity that may underlie learning and memory, is attenuated by blocking neuron activity of the basolateral amygdala (BLA). In the present study we investigated the amygdala noradrenergic or cholinergic contribution to hipp...

journal_title：Neuroreport

authors： Ikegaya Y,Nakanishi K,Saito H,Abe K

更新日期：1997-09-29 00:00:00

abstract：:Ts65DN mice were developed as a model of Down syndrome (DS); they are trisomic for the distal segment of chromosome 16 (MMU16), which contains genes syntenic with some of the genes located on the critical region of human chromosome 21 (HSA21). Since behavioral and neurochemical disturbances have been observed in this ...

journal_title：Neuroreport

authors： Megías M,Verduga R,Dierssen M,Flórez J,Insausti R,Crespo D

更新日期：1997-11-10 00:00:00

abstract：:The aim of this study is to investigate the neural mechanism of extending a brand in a specific product category to other product categories. Facing two sequential stimuli in pairs consisting of beverage brand names (stimulus 1) and product names (stimulus 2) in other categories, 16 participants were asked to indicate...

journal_title：Neuroreport

authors： Ma Q,Wang X,Dai S,Shu L

更新日期：2007-07-02 00:00:00