Limb flexion reflex-related areas in human cerebellum.

Abstract:

:Numerous studies have shown that the cerebellum is involved in classical conditioning of specific aversive reactions. Only few studies, however, have examined the exact localization of cerebellar areas involved in the control of unconditioned reflex responses. The present study investigated cerebellar areas, which are activated during eliciting of the limb flexion reflex in healthy controls using [15O]H2O PET. Limb flexion reflex related areas were found in vermal lobules III-VI with the local maximum in vermal lobule V. Areas of activation were more widespread compared to a voluntary foot movement and a sensory foot stimulation condition. Limb flexion reflex areas probably reflect efferent reflex modulation as well as sensory inputs from the stimulus itself and/or the reflex response.

journal_name

Neuroreport

journal_title

Neuroreport

authors

Maschke M,Erichsen M,Drepper J,Jentzen W,Müller SP,Kolb FP,Diener HC,Timmann D

doi

10.1097/00001756-200212030-00031

subject

Has Abstract

pub_date

2002-12-03 00:00:00

pages

2325-30

issue

17

eissn

0959-4965

issn

1473-558X

journal_volume

13

pub_type

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