Abstract:
:Temporal changes of serotonin (5-HT) content in the median (MRN) and dorsal (DRN) raphe nuclei were measured in rats kept under various lighting conditions. Serotonin content in the MRN and DRN under light-dark (LD) condition showed diurnal rhythmicity, with a peak during early light phase and a trough during the dark phase. In constant dark (DD) condition, a single peak was observed and was out of phase to the 5-HT peak found under LD condition. Animals exposed to constant light (LL) after 2 days in DD showed marked increase in 5-HT after lights on. These results suggest that changes in 5-HT in the MRN and DRN are regulated by an endogenous pacemaker and by light.
journal_name
Neuroreportjournal_title
Neuroreportauthors
Cagampang FR,Yamazaki S,Otori Y,Inouye SIdoi
10.1097/00001756-199310000-00012subject
Has Abstractpub_date
1993-10-25 00:00:00pages
49-52issue
1eissn
0959-4965issn
1473-558Xjournal_volume
5pub_type
杂志文章相关文献
NEUROREPORT文献大全abstract::Retinal light exposure induces several immediate-early genes in the hypothalamic suprachiasmatic nucleus (SCN), which contains the major circadian pacemaker of mammals. Clock-controlled and light-induced genes expressed in the SCN such as c- and contain upstream regulatory elements similar to those of the major immedi...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200303030-00029
更新日期:2003-03-03 00:00:00
abstract::Endothelin-1 (ET-1) is recognized as being involved in the pathophysiology of cerebrovascular diseases. Using organ culture as a model for possible pathological changes we studied changes in ET(A) and ETB receptor function using a sensitive in vitro method. We observed an up-regulation of the ET(B) receptor and an ama...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200002280-00042
更新日期:2000-02-28 00:00:00
abstract::Adult rats were studied for serotonin and its metabolite in basal ganglia, nociceptive responses to electric current and tremor induced by 5-methoxy-N,N-dimethyltryptamine (5-MeODMT) to assess the effects of a single systemic injection of serotonin antiserum given at 1 day old. Antiserum-treated animals showed no over...
journal_title:Neuroreport
pub_type: 杂志文章
doi:
更新日期:1995-12-29 00:00:00
abstract::When examining a buying process, changes in human brain signals and their event-related potential (ERP) components can be considered a reflection of the consumers' emotions. In this experiment, participants were shown 12 products and related services that were available for purchase. After recording ERP components, we...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000457
更新日期:2015-12-02 00:00:00
abstract::The amount of backward walking induced in mice by co-administration of clenbuterol, a beta-adrenoceptor agonist and putative antidepressant, and the benzodiazepine chlordiazepoxide was plotted as a three-dimensional surface, using modified Uniras software. The surface was compared with the theoretical surface to be ex...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199207000-00021
更新日期:1992-07-01 00:00:00
abstract::The rat synaptosomal membrane antigen D3, which has been studied for more than 20 years since its first demonstration as a brain-specific protein, was shown to bind monoclonal antibodies to SNAP-25, a presynaptic plasma membrane-associated protein. In addition to SNAP-25, anti-D3 antiserum also precipitated two polype...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199512000-00017
更新日期:1995-12-29 00:00:00
abstract::Removal of the labyrinthine organs on one side results in static and dynamic disturbances. Some functional recovery occurs over time and is paralleled in frogs by an increase in the efficacy of central vestibular pathways. Here, we report concomitant increases in dorsal root evoked ventral root responses in the brachi...
journal_title:Neuroreport
pub_type: 杂志文章
doi:
更新日期:1993-09-01 00:00:00
abstract::Sensory funneling of liminal multiple-point air-puff stimulation on the skin was evaluated by measuring somatosensory evoked potentials (SEPs), reaction time (RT) and subjective detection threshold. Single-point air-puffs at the threshold intensity, and 2-point and 3-point air-puffs (10 mm apart) of the same intensity...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199910190-00014
更新日期:1999-10-19 00:00:00
abstract::1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity reproduces many of the features of Parkinson's disease (PD). alpha-Synuclein has been identified as a prominent component of the Lewy body (LB), the pathological hallmark of PD. MPTP-treated primates have been reported to develop intraneuronal inclusion...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200001170-00041
更新日期:2000-01-17 00:00:00
abstract::The amygdala and ventral portion of the periaqueductal gray (vPAG) are crucial for the expression of the contextual freezing behavior. However, it is still unclear whether the amygdala also plays a role in defensive behaviors induced by electrical stimulation of the dorsal periaqueductal gray (dPAG). In the present st...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200410050-00028
更新日期:2004-10-05 00:00:00
abstract::The functions of the fields of the mammalian auditory cortex in sound perception and recognition are unknown. We used Fos (a protein of the inducible immediate-early gene c-fos) as a cellular marker of activated brain areas to show in the mouse (Mus domesticus) that sound is processed differentially in auditory cortic...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199908020-00022
更新日期:1999-08-02 00:00:00
abstract::The benzodiazepine, lorazepam enhances the efficiency of local, inhibitory GABA(A) synapses in the cortex, which stabilize postsynaptic, excitatory activity by synchronizing their own discharges at around 40 Hz. Treatment with lorazepam has also been shown to adversely influence detection performance in perceptual tas...
journal_title:Neuroreport
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00001756-200010200-00027
更新日期:2000-10-20 00:00:00
abstract::Previous research has suggested that exposure to radiofrequency electromagnetic fields increases electroencephalogram spectral power in non-rapid eye movement sleep. Other sleep parameters have also been affected following exposure. We examined whether aspects of sleep architecture show sensitivity to electromagnetic ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000186593.79705.3c
更新日期:2005-11-28 00:00:00
abstract::Spatial neglect has been explained as an impairment in the representation of extrapersonal space. One account suggests that representations of extrapersonal space are spatially compressed following neglect. In support of this view it has been demonstrated that neglect patients systematically underestimate the size of ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199712010-00035
更新日期:1997-12-01 00:00:00
abstract::Previous studies have shown that spatial memory retention is affected by the metabotropic glutamate receptor (mGluR) influencing agents (R,S)-alpha-methyl-4-carboxyphenylglycine (MCPG) and trans-azetidine-2,4-dicarboxylic acid (tADA). In the present investigation we examined whether the mGluR antagonist MCPG (20 mM an...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199511270-00027
更新日期:1995-11-27 00:00:00
abstract::Damage to central nervous system white matter is observed following hypoglycemia, raising the possibility that hypoglycemia influences oligodendrocytes and myelination. To examine effects of hypoglycemia on oligodendrocytes and myelin formation, we studied cultured oligodendrocyte precursor cells and cerebellar slice ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000192733.00535.b6
更新日期:2006-01-23 00:00:00
abstract::Myristoylated alanine-rich C kinase substrate (MARCKS), an acidic protein associated with cell motility and phagocytosis, is activated upon phosphorylation by protein kinase C (PKC) and proline-directed protein kinases. In Alzheimer disease (AD), activated microglia expressing MARCKS migrates around senile plaques. We...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200108080-00055
更新日期:2001-08-08 00:00:00
abstract::Mental rotation performance has been found to produce one of the largest sex differences in cognition. Many theories suggest that this effect should be accompanied by a sex difference in functional cerebral asymmetry, but empirical data are more than equivocal probably because of (a) the use of inappropriate stimuli a...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0000000000000198
更新日期:2014-08-06 00:00:00
abstract::NCAM-180 knockout mice, which have documented deficits in neural migration, were used to determine whether developmental abnormalities could lead to morphological changes and alterations in sensory motor gating mechanisms. Measurement of the lateral ventricle showed that NCAM-180-/- mice had marked increases in both t...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199802160-00019
更新日期:1998-02-16 00:00:00
abstract::Previous event-related potential studies in Indo-European languages reported a surprising finding that failed syntactic category processing appears to block lexical-semantic integration, suggesting a functional primacy of syntax over semantics. An event-related potential experiment was conducted to test whether there ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e3282fda21d
更新日期:2008-05-07 00:00:00
abstract::The dynamics of intracellular calcium concentration ([Ca2+]i) following activation of low voltage-activated (LVA) and high voltage-activated (HVA) Ca2+ currents were studied in identified relay neurons and interneurons of the rat dorsal lateral geniculate nucleus (LGNd) in situ using Ca2+ imaging and patch-clamp techn...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199707280-00001
更新日期:1997-07-28 00:00:00
abstract::Musical expertise has been shown to induce widespread structural and functional alterations in the brain, even-handedly affecting top-down and bottom-up factors. At the same time, it is known that the early evoked gamma-band response (GBR) can be modulated by top-down as well as bottom-up factors such as attention and...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e328360abdb
更新日期:2013-06-19 00:00:00
abstract::The aim was to study whether there is indication of a dissociation in processing of visuospatial and colour information in working memory in humans. Experimental subjects performed visuospatial and colour n-back tasks with and without visuospatial and colour distractive stimuli presented in the middle of the delay per...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199908020-00002
更新日期:1999-08-02 00:00:00
abstract::ERPs were recorded from subjects performing semantic and rhyme matching tasks using either spoken words, printed words or pictures as stimuli. Mismatches enhanced N400 (in the semantic task) and N450 (in the rhyme task). Onset and peak latencies were shorter for N450 than for N400 with spoken words; this relationship ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199410270-00046
更新日期:1994-10-27 00:00:00
abstract::Male Bengalese finches sing complex song sequences during courtship. To examine the female perception of sequence complexity, we tested female auditory processing with respect to sequential differences in the caudomedial nidopallium and caudomedial mesopallium. Repeated song presentations caused lower expression of th...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/WNR.0b013e32833730b7
更新日期:2010-04-21 00:00:00
abstract::Motor fluctuations that ultimately complicate the response of most parkinsonian patients to levodopa therapy might represent a form of behavioral or neuronal plasticity. Since various forms of neuronal plasticity appear to be mediated by glutamate transmission through the N-methyl-D-aspartate (NMDA) receptor, the effe...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199412000-00045
更新日期:1994-12-20 00:00:00
abstract::Optical imaging of rat barrel cortex has provided detailed spatio-temporal maps of functional cortical architecture. We describe an event-related procedure (ERP) for optical imaging based on selective signal averaging as reported by Burock et al., using an anti-correlative pseudo-random event sequence. The sequence us...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200007140-00037
更新日期:2000-07-14 00:00:00
abstract::Plasticity in the central nervous system may play an important role in clinical pain. The present study shows that long-term potentiation (LTP) may be induced in single wide dynamic range (WDR) neurons in the dorsal horn after high-frequency stimulation of the sciatic nerve in intact urethane anaesthetized rats. Extra...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199711100-00002
更新日期:1997-11-10 00:00:00
abstract::We recently reported behavioral improvements following intrastriatal transplantation of cryopreserved cultured human neuroteratocarcinoma-derived cells (hNT neurons) in rats with cerebral ischemia induced by occlusion of the middle cerebral artery. In the present study, the viability and survival of hNT neurons were e...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-199808240-00028
更新日期:1998-08-24 00:00:00
abstract::The mismatch negativity (MMN) reflects the neural representation of the acoustic environment stored in sensory memory. The short phase of sensory memory corresponds to the temporal window of integration (TWI) which integrates the neighboring sounds into a unitary event. We measured the magnetic MMN (MMNm) and the disc...
journal_title:Neuroreport
pub_type: 杂志文章
doi:
更新日期:2004-12-22 00:00:00