Posterior amorphous corneal dystrophy. An ultrastructural study of a variant with histopathological features of an endothelial dystrophy.

abstract：:Immunologic rejection is the main cause of corneal graft failure, especially in vascularized corneal beds. The purpose of this study was to investigate the effect of systemic Cyclosporine-A (CsA) on the survival of corneal allografts in heavily vascularized rabbit corneal beds, following alkali burn. Heavy corneal vas...

journal_title：Cornea

authors： Rehany U,Waisman M

更新日期：1994-09-01 00:00:00

abstract：PURPOSE:To evaluate the treatment with topical 1% cyclosporine A (CsA) in patients with subepithelial corneal infiltrates (SEIs). METHODS:We retrospectively reviewed the records of 9 patients (12 eyes) before and after the treatment with CsA 1% eyedrops twice daily. All patients had been treated with topical corticost...

journal_title：Cornea

authors： Levinger E,Slomovic A,Sansanayudh W,Bahar I,Slomovic AR

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:To investigate the feasibility of corneal reconstruction utilizing cultured human corneal endothelial cells (HCECs). METHODS:We cultivated HCECs using culture dishes pre-coated with bovine corneal endothelial extracellular matrix. The effect of donor age on HCECs was investigated. We reconstructed corneas usin...

journal_title：Cornea

authors： Amano S

更新日期：2003-10-01 00:00:00

abstract：PURPOSE:To examine the corneal transplant rejection rate and the rate of graft failure subsequent to rejection in the first 2 years after endothelial keratoplasty (EK) and to compare this to background data for similar cases of penetrating keratoplasty (PK). METHODS:Anonymized data from consecutive cases of EK [deep l...

journal_title：Cornea

authors： Allan BD,Terry MA,Price FW Jr,Price MO,Griffin NB,Claesson M

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:To report the case of a patient who initially presented with primary acquired melanosis (PAM) without atypia of the conjunctiva and later developed lentigo maligna of the eyelids and PAM with atypia of the conjunctiva. We illustrate the utility of combination topical therapy with adjunctive cryotherapy to treat...

journal_title：Cornea

authors： Bratton EM,Knutsen-Larson S,Durairaj VD,Gregory DG,Mellette JR

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To describe the clinical characteristics, diagnosis, treatment, and visual outcome of 61 cases of Fusarium keratitis in Mexico. METHODS:Retrospective, comparative study of 61 patients with clinically and culture-confirmed Fusarium keratitis, who were attended at an eye hospital in Mexico City from 1981 to 2001...

journal_title：Cornea

authors： Pérez-Balbuena AL,Vanzzini-Rosano V,Valadéz-Virgen Jde J,Campos-Möller X

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:The study aimed to determine whether detectable concentrations of colchicine are present in the tear fluid of treated patients with familial Mediterranean fever (FMF) and thus demonstrate a possible route by which colchicine reaches the corneal surface. METHODS:Tear fluid samples (50-100 microL) were collected...

journal_title：Cornea

authors： Leibovitch I,Alster Y,Scherrmann JM,Azmon B,Barequet IS,Livneh A,O'Brien TP,Lazar M,Loewenstein A

更新日期：2003-04-01 00:00:00

abstract：PURPOSE:To report a cluster of postoperative Acanthamoeba endophthalmitis after routine cataract surgeries. METHODS:A brief summary of sentinel events leading to the referral of 4 patients of postoperative endophthalmitis to our hospital is followed by clinical descriptions and the various diagnostic approaches and in...

journal_title：Cornea

authors： Rammohan R,Hajib Naraharirao M,Veerappan S,Vijayaraghavan P,Rajaraman R,Manayath GJ,Dsouza P,Radhakrishnan S,Venkatapathy N,Lakshmipathi D,Madhuravasal Krishnan J,Raghavan A

更新日期：2021-02-01 00:00:00

abstract：PURPOSE:To assess the characteristics of BioMask as a potential masking agent for use with the excimer laser. METHOD:We addressed ablation rate, smoothness, ease of use, dioptric shift, treatment of standardized irregular topography, and ability of BioMask to induce dioptric change in vivo. RESULTS:BioMask ablates at...

journal_title：Cornea

authors： Stevens SX,Bowyer BL,Sanchez-Thorin JC,Rocha G,Young DA,Rowsey JJ

更新日期：1999-03-01 00:00:00

abstract：PURPOSE:To describe the histopathology of the cornea in microphthalmia with linear streaks (MLS) syndrome. METHODS:Two patients with MLS syndrome underwent penetrating keratoplasty. This study describes the histopathology and investigates immunophenotype of the corneal extracellular matrix by using keratan sulfate and...

journal_title：Cornea

authors： Kapur R,Tu EY,Toyran S,Shah P,Vangveeravong S,Lloyd WC 3rd,Edward DP

更新日期：2008-07-01 00:00:00

abstract：PURPOSE:To describe a new technique for donor insertion in cases of Descemet-stripping automated endothelial keratoplasty (DSAEK). METHODS:This is a retrospective case series study of a novel method to introduce the donor tissue in DSAEK. This is a report of 16 cases that underwent the DSAEK procedure. The surgical te...

journal_title：Cornea

authors： Sarnicola V,Toro P

更新日期：2008-08-01 00:00:00

abstract：:To determine the diagnostic usefulness of routine staining of corneal buttons with alcian blue, we evaluated 150 consecutive corneal specimens with hematoxylin and eosin and alcian blue stains. Overall, 67% of specimens demonstrated deposition of acid mucopolysaccharide. More specifically, positive alcian blue stainin...

journal_title：Cornea

authors： Weiss JS,Orlando F,Albert DM

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:To evaluate the effect of obstructive sleep apnea-hypopnea syndrome (OSAHS) on the meibomian glands, ocular surface, and tear parameters. METHODS:The study included 59 individuals (32 subjects with OSAHS, 27 control subjects) who underwent polysomnography in the Chest Diseases Clinic. The right eyes of all ind...

journal_title：Cornea

authors： Muhafiz E,Ölçen M,Erten R,Bozkurt E

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:To measure the refractive index (RI) of the human corneal stroma in vivo using an objective Abbé refractometer (VCH-1) and to determine if RI of the stroma is related to age. METHODS:VCH-1 was used to measure RI at the central anterior stroma immediately after lifting the flap in neophyte patients preselected ...

journal_title：Cornea

authors： Amparo F,Patel S,Alió JL,Rodriguez-Prats JL,Moreno LJ

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:To assess the repeatability of densitometry, a measure of corneal haze, in the control (group I), keratoconic (group II), and postcollagen cross-linking (CXL, group III) eyes as measured on Scheimpflug imaging. METHODS:Densitometry values for 160 eyes of 160 patients (50 eyes of 50 patients in group I, 50 eyes...

journal_title：Cornea

authors： Pahuja N,Shetty R,Subbiah P,Nagaraja H,Nuijts RM,Jayadev C

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of superficial keratectomy and conjunctival advancement hood flap (SKCAHF) for the treatment of bullous keratopathy in canine patients. METHODS:Nine dogs (12 eyes) diagnosed with progressive corneal edema underwent superficial keratectomy followed by placement of conjunctival advanceme...

journal_title：Cornea

authors： Horikawa T,Thomasy SM,Stanley AA,Calderon AS,Li J,Linton LL,Murphy CJ

更新日期：2016-10-01 00:00:00

abstract：:The mechanism of ocular surface allergy in the forms of atopic conjunctivitis and vernal keratoconjunctivitis has been highlighted by specific functions of chemokines. In the context of late-phase allergic responses, these molecules have key roles in recruitment and activation of leukocytes. Their interaction with lig...

journal_title：Cornea

authors： Miyazaki D,Nakamura T,Komatsu N,Nawata N,Ikeda Y,Inoue Y,Higashi H,Ono SJ

更新日期：2004-11-01 00:00:00

abstract：:The objective of this study was to compare four methods of counting corneal endothelial cell density using the Topcon SP 1000 microscope and Image-NET digital graphic software. Two independent observers quantified cell density from 63 endothelial photomicrographs using the various standardized techniques. The first me...

journal_title：Cornea

authors： Vecchi M,Braccio L,Orsoni JG

更新日期：1996-05-01 00:00:00

abstract：PURPOSE:To compare intracameral 20% sulfur hexafluoride (SF6) versus 100% air as tamponade for graft attachment in Descemet membrane endothelial keratoplasty (DMEK). METHODS:Using an electronic database search on MEDLINE and CENTRAL from inception to December 2017, we performed a literature review and meta-analysis in...

journal_title：Cornea

authors： Marques RE,Guerra PS,Sousa DC,Ferreira NP,Gonçalves AI,Quintas AM,Rodrigues W

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:To investigate if amniotic membrane incubated with antibiotics could inhibit bacterial growth in vitro. METHODS:Amniotic membrane fragments were incubated with the antibiotics (netilmicin) solution; the washed and drained fragments were either tested after treatment or further incubated in antibiotic-free medi...

journal_title：Cornea

authors： Mencucci R,Menchini U,Dei R

更新日期：2006-05-01 00:00:00

abstract：PURPOSE:To study the corneal biocompatibility of bevacizumab on various cultured human corneal cells. METHODS:Cell cultures of corneal keratinocytes (CKs), corneal fibroblasts (CFs), and corneal endothelial cells (CECs) were harvested from human donor eyes and exposed to various concentrations of bevacizumab (0.25-5.0...

journal_title：Cornea

authors： Yoeruek E,Spitzer MS,Tatar O,Aisenbrey S,Bartz-Schmidt KU,Szurman P

更新日期：2007-09-01 00:00:00

abstract：PURPOSE:To bioengineer a corneal surface replacement using ex vivo expanded, cultured corneal epithelial stem cells seeded on a matrix derived from amniotic membrane and use this bioengineered graft to manage difficult ocular surface disease. METHODS:Fourteen patients with ocular surface disease unresponsive to standa...

journal_title：Cornea

authors： Schwab IR,Reyes M,Isseroff RR

更新日期：2000-07-01 00:00:00

abstract：PURPOSE:To report a case of traumatic flap partial dislocation and subsequent diffuse lamellar inflammation 14 months after laser in situ keratomileusis (LASIK) retreatment. METHODS:Case report of a late flap dislocation that occurred during routine recreational activity (struck with a finger in the right eye while pl...

journal_title：Cornea

authors： Aldave AJ,Hollander DA,Abbott RL

更新日期：2002-08-01 00:00:00

abstract：PURPOSE:To develop a rat model of chronic Acanthamoeba polyphaga keratitis suitable for pharmacologic assessment of therapeutic agents. METHODS:An A. polyphaga isolate (ATCC #50495) was grown in peptone-yeast extract-glucose medium. Five-weeks-old, Sprague-Dawley male rats were injected with 10(3) or 10(4) trophozoite...

journal_title：Cornea

authors： Vasseneix C,Gargala G,François A,Hellot MF,Duclos C,Muraine M,Benichou J,Ballet JJ,Brasseur G,Favennec L

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:To compare the rate of epithelial healing of corneal erosion in an animal model with 2 commercial formulations of fourth-generation fluoroquinolones: 0.3% gatifloxacin and 0.5% moxifloxacin. METHODS:Corneal erosions, 6 mm in diameter, were created in 28 rabbit eyes. The rabbits were randomized to receive topic...

journal_title：Cornea

authors： Barequet IS,Habot-Wilner Z,Lavinsky F,Ziv H,Belkin M,Rosner M

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:To evaluate tear osmolarity and tear film parameters in patients with vitiligo. METHODS:A total of 25 eyes of 25 patients with vitiligo with periocular involvement (group 1), 30 eyes of 30 patients with vitiligo without periocular involvement (group 2), and 20 eyes of 20 controls (group 3) were evaluated using...

journal_title：Cornea

authors： Erdur SK,Aydin R,Balevi A,Ozsutcu M,Kocabora MS

更新日期：2018-04-01 00:00:00

abstract：PURPOSE:The purpose of this study was to report the first case of fungal keratitis resulting from Thielavia sp. METHODS:We conducted a retrospective chart review. RESULTS:A 10-year old girl presented 2 weeks after ocular plant injury with pain and corneal stromal infiltration with central ulceration and ill-defined m...

journal_title：Cornea

authors： Theoulakis P,Goldblum D,Zimmerli S,Muehlethaler K,Frueh BE

更新日期：2009-10-01 00:00:00

abstract：PURPOSE:The purpose of this research is 2-fold. First of all, the level of keratopathy development in patients with congenital aniridia is studied. In addition, a correlation between the effects of ocular surgery on the severity of keratopathy is made. METHODS:A thorough search for the total number of patients with an...

journal_title：Cornea

authors： Edén U,Riise R,Tornqvist K

更新日期：2010-10-01 00:00:00

abstract：PURPOSE:To describe whether subconjunctival bevacizumab decreases corneal neovascularization in patients with ocular surface inflammatory diseases. METHODS:The study is a retrospective case series that includes 8 eyes of 7 patients with corneal neovascularization. Patients received 1-3 injections of 2.5 mg subconjunct...

journal_title：Cornea

authors： Doctor PP,Bhat PV,Foster CS

更新日期：2008-10-01 00:00:00

abstract：PURPOSE:This study explored a new method for removing thermosensitive acrylic punctal plugs from lacrimal puncta. METHODS:A total of 14 dry eye patients (14 eyes), who required the removal of thermosensitive acrylic punctal plugs from the lacrimal puncta because of serious complications, were recruited. Among the 14 p...

journal_title：Cornea

authors： Zhang M,Zhang X

更新日期：2015-12-01 00:00:00