Abstract:
:To determine the diagnostic usefulness of routine staining of corneal buttons with alcian blue, we evaluated 150 consecutive corneal specimens with hematoxylin and eosin and alcian blue stains. Overall, 67% of specimens demonstrated deposition of acid mucopolysaccharide. More specifically, positive alcian blue staining was observed in 88% of specimens with pannus, 83% of specimens with stromal downgrowth, 71% of specimens with stromal scarring, and 67% of specimens with interstitial keratitis. In 80% of these cases, the positive alcian blue stain correlated to pathology noted on hematoxylin and eosin sections. In 20% of cases, we could not explain the reason for the presence of alcian blue staining. Except for macular dystrophy of the cornea, the presence, strength, and location of staining did not provide useful information in terms of making a specific clinical diagnosis. Consequently, alcian blue should be used only in those settings in which the pathologist needs to document or confirm the abnormal presence or absence of acid mucopolysaccharide deposition.
journal_name
Corneajournal_title
Corneaauthors
Weiss JS,Orlando F,Albert DMsubject
Has Abstractpub_date
1988-01-01 00:00:00pages
127-32issue
2eissn
0277-3740issn
1536-4798journal_volume
7pub_type
杂志文章相关文献
CORNEA文献大全abstract:PURPOSE:Comparison of corneal pachymetry assessment with ultrasound and Orbscan II using acoustic factor and subtraction methods. METHODS:Ultrasound and Orbscan pachymetry for all patients with LASIK performed between July 2002 and May 2003 were retrospectively analyzed. Comparison between the 2 preoperative measureme...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000240089.26467.dc
更新日期:2006-12-01 00:00:00
abstract:PURPOSE:Intrastromal corneal ring segments (ICRSs) are small arc-like implants that are being used increasingly as a minimally invasive treatment for patients with keratoconus. This study assessed the effectiveness of KeraRing implants, a type of ICRS, to treat keratoconus. METHODS:Retrospective case series descriptiv...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3182215a15
更新日期:2012-02-01 00:00:00
abstract::Detachment of Descemet's membrane is an unusual cause of postoperative corneal edema. The typical detachment is small and usually limited to the area near the limbal wound. These peripheral detachments usually heal without sequelae as endothelium spreads over the area and secretes a new Descemet's membrane. We report ...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract:PURPOSE:To identify whether histopathologic presence of neovascularization is predictive for allograft failure following penetrating keratoplasty for herpes simplex virus (HSV) keratitis. METHODS:Retrospective, interventional case series of 62 consecutive patients with HSV keratitis who underwent penetrating keratopla...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31819c4e55
更新日期:2009-10-01 00:00:00
abstract:PURPOSE:To evaluate the suitability of corneas from septic donors for transplantation by analyzing the discard rate in the eye bank and the clinical outcome of Descemet membrane endothelial keratoplasty (DMEK) using organ-cultured corneal grafts from septic versus nonseptic donors. METHODS:This retrospective study inc...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002443
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:We report a patient with progressive idiopathic, nonulcerative, noninflammatory, avascular, bilateral, paracentral and peripheral corneal thinning monitored for 13 years. METHODS:Because of progressive corneal thinning, the patient underwent several surgical procedures, including an arcuate lamellar keratectom...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract:PURPOSE:To describe a technique for Nd:YAG laser photodiscission of retroprosthetic membrane (RPM) in keratoprosthesis patients that minimizes damage to the optic. METHODS:Prospective review of Boston type I keratoprosthesis patients at 1 site who received Nd:YAG treatment for RPM from 2005 to 2009. Outcomes were base...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181cda001
更新日期:2010-10-01 00:00:00
abstract:PURPOSE:Corneal inflammation in overnight contact lens (CL) wear is not fully understood. We designed a masked study to examine the impact of overnight CL wear on clinical variables in subjects who had previously experienced corneal inflammatory disease. METHODS:Forty-four subjects were entered into the study: Nine su...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200307000-00010
更新日期:2003-07-01 00:00:00
abstract:PURPOSE:To evaluate the anterior segment parameters in patients with osteogenesis imperfecta (OI) compared with healthy control subjects. METHODS:Seventeen patients with OI and 19 age-matched healthy controls were included into this cross-sectional case-control study. Corneal topographic, topometric and Belin-Ambrósio...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002345
更新日期:2020-08-01 00:00:00
abstract:PURPOSE:To report a case of partial scleral rupture after laser in situ keratomileusis (LASIK) surgery. METHODS:This is a retrospective case report describing a late complication of LASIK surgery. RESULTS:A 32-year-old white woman with a history of LASIK surgery performed with a mechanical microkeratome 4 years previ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001850
更新日期:2019-04-01 00:00:00
abstract:PURPOSE:To determine the effects of single radial or horizontal suture placement in 2-step clear corneal incision (CCI) wound apposition and permeability to particles of India ink. METHODS:Five fresh human globes were included. Two 25-gauge needles connected to a saline solution bag and to a digital manometer were ins...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31824d0d45
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:To describe a new minimally invasive surgical technique for the symptomatic management of bullous keratopathy in blind eyes. METHODS:Four patients with severe corneal edema due to endothelial decompensation and no visual function in the affected eye presented for the relief of their ocular symptoms (pain and t...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000081
更新日期:2014-05-01 00:00:00
abstract::In order to evaluate the effect of a commonly used sodium hyaluronate preparation (Healon, Pharmacia AB, Uppsala, Sweden) on the incidence of endothelial rejection, endothelial cell loss, intraocular pressure, and corneal thickness after penetrating keratoplasty, we conducted a randomized clinical trial. Patients were...
journal_title:Cornea
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1990-10-01 00:00:00
abstract:PURPOSE:Laser-assisted epilation of eyebrow hair has become a common practice, but a number of ocular complications can occur. We report the cases of 2 patients who had unilateral anterior uveitis after having undergone laser removal of eyebrow hair. METHODS:This report describes 2 patients who experienced eye pain, p...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000294
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:To determine the prevalence of hepatitis B (HBV), hepatitis C (HCV), and human immunodeficiency virus (HIV) in the serum of cornea donors who had been previously screened by social and medical history by the Eye Bank of Canada, Ontario Division. METHOD:A retrospective examination of the donor records of the Ey...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract:PURPOSE:Using CJLAT, a chimeric herpes simplex virus (HSV-1) that produces a high incidence of herpes stromal keratitis (HSK) in latently infected rabbits, and in vivo confocal microscopy (CM), we characterized the cellular events that precede the development of HSK. METHODS:Thirty days after infection, in vivo CM was...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000666
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:To report a case of direct contact xylene-related vacuolar keratopathy. METHODS:Interventional case report and review of the literature. RESULTS:Xylene keratopathy is a distinct clinical entity characterized by significantly decreased visual acuity, increased corneal thickness, and the presence of corneal epi...
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/00003226-200301000-00023
更新日期:2003-01-01 00:00:00
abstract:PURPOSE:To evaluate the accuracy and precision of corneal flap thickness following laser in situ keratomileusis (LASIK) performed using the 140-, 160-, and 180-microm heads for the Amadeus microkeratome (AMO, Irvine, CA). SETTING:The study took place at the Cullen Eye Institute, Baylor College of Medicine, Houston. M...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200308000-00003
更新日期:2003-08-01 00:00:00
abstract:PURPOSE:To investigate agreement between rotating Scheimpflug camera (Pentacam HR, Oculus) and rotating Scheimpflug camera combined with Placido disc corneal topography (Sirius, CSO) in measuring total corneal astigmatism (TCA). METHODS:In this observational study, all patients undergoing cataract surgery with preoper...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001117
更新日期:2017-04-01 00:00:00
abstract:PURPOSE:To describe the histopathology of the cornea in microphthalmia with linear streaks (MLS) syndrome. METHODS:Two patients with MLS syndrome underwent penetrating keratoplasty. This study describes the histopathology and investigates immunophenotype of the corneal extracellular matrix by using keratan sulfate and...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000611352.03660.a7
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVE:To determine the intrastromal layer of corneal deposits in granular corneal dystrophy (GCD). DESIGN:Investigative case report. METHODS:A 32-year-old woman with bilateral decreased vision because of corneal deposits was examined with cross-sectional scans using optical coherence tomography (OCT). RESULTS:Vi...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200404000-00009
更新日期:2004-04-01 00:00:00
abstract:PURPOSE:To determine the benefit of bilateral penetrating keratoplasty with regard to binocular vision. METHODS:We compared patients who underwent corneal transplantation bilaterally with patients who had successful corneal transplantation in one eye and corneal disease in the other eye. Specifically, changes in fusio...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200107000-00006
更新日期:2001-07-01 00:00:00
abstract:PURPOSE:Posterior amorphous corneal dystrophy (PACD) is a rare disorder characterized by sheet-like opacification of the posterior corneal stroma, corneal thinning, and decreased corneal curvature. It is not known to be associated with progressive corneal ectasia. In this report, we examine the course of a patient with...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001304
更新日期:2017-12-01 00:00:00
abstract:PURPOSE:To present a novel noncontact meibography system with anterior segment optical coherence tomography (OCT), which is widely used in clinics for the anterior segment (cornea, anterior chamber angle, etc.), and compare the results with preexisting infrared meibography. METHODS:This research was carried out at the...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318247b2fd
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:We characterized the presence of hemangiogenesis (HA) and lymphangiogenesis (LA) in human corneal specimens exhibiting 13 underlying pathologies. METHODS:Human corneal specimens were obtained from consenting subjects (n = 2 or n = 3 for each pathology; total sample size, n = 35). The pathological specimens wer...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31821dd986
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:To assess the relationship between corneal thinning measured by clinician-graded slit-lamp examination compared with ultrasound pachymetry (USP), anterior segment optical coherence tomography (AS-OCT), and the Pentacam. METHODS:Patients with corneal thinning underwent USP, AS-OCT, Pentacam measurements and sta...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001151
更新日期:2017-04-01 00:00:00
abstract:PURPOSE:To determine the mean corneal diameter and its determinants in the population of Tehran. METHODS:From the Tehran Eye Study participants who were sampled through a stratified cluster approach, those in the first 4 municipality districts of Tehran were selected, and after applying the inclusion and exclusion cri...
journal_title:Cornea
pub_type: 杂志文章,多中心研究
doi:10.1097/ICO.0b013e3181a9d0a9
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:To evaluate and compare corneal higher-order aberrations (HOAs) after Descemet stripping automated endothelial keratoplasty (DSAEK), femtosecond laser-assisted penetrating keratoplasty (FLAK), and conventional penetrating keratoplasty (PKP). METHODS:A retrospective comparison of consecutive surgical series of ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3182151df2
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:To report the outcome and the reversibility of refractive outcomes after intrastromal corneal ring segment (ICRS) explantation in patients with keratoconus treated with ICRS implantation and same-day collagen crosslinking (CXL). METHODS:This is a retrospective review of ICRS explantation in 3 eyes of 3 patient...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3182a738ba
更新日期:2013-12-01 00:00:00
abstract:PURPOSE:To compare the accuracy of impression cytology in the diagnosis of ocular surface neoplasia with tissue histology. METHODS:We reviewed the histories of patients diagnosed with ocular surface neoplasia at the Chiang Mai University Hospital. All patients underwent both impression cytology and tissue biopsy. We c...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31815b9402
更新日期:2008-04-01 00:00:00