Herpes simplex virus keratitis: histopathologic neovascularization and corneal allograft failure.

abstract：PURPOSE:To evaluate and compare corneal thickness in normal and dry eyes. METHODS:The Orbscan corneal topography system was used to measure the corneal thickness at nine locations in the central and peripheral (superior, superonasal, nasal, inferonasal, inferior, inferotemporal, temporal, superotemporal) cornea in 38 ...

journal_title：Cornea

authors： Liu Z,Pflugfelder SC

更新日期：1999-07-01 00:00:00

abstract：PURPOSE:To determine if superficial lamellar corneal excision with femtosecond laser followed by phototherapeutic keratectomy (PTK) using a masking substance improves visual acuity and optical quality of patients with severe corneal opacities. METHODS:Twelve eyes with corneal haze or scarring underwent confocal micros...

journal_title：Cornea

authors： Alió JL,Agdeppa MC,Uceda-Montanes A

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:To describe the histopathology of the cornea in microphthalmia with linear streaks (MLS) syndrome. METHODS:Two patients with MLS syndrome underwent penetrating keratoplasty. This study describes the histopathology and investigates immunophenotype of the corneal extracellular matrix by using keratan sulfate and...

journal_title：Cornea

authors： Kapur R,Tu EY,Toyran S,Shah P,Vangveeravong S,Lloyd WC 3rd,Edward DP

更新日期：2008-07-01 00:00:00

abstract：PURPOSE:To measure subbasal nerve density and orientation in normal human corneas across a broad age range. METHODS:Sixty-five normal corneas of 65 subjects were examined by using tandem scanning confocal microscopy. Ages of subjects ranged from 15 to 79 years (mean 46 +/- 19 years), with 5 subjects from each hemideca...

journal_title：Cornea

authors： Erie JC,McLaren JW,Hodge DO,Bourne WM

更新日期：2005-08-01 00:00:00

abstract：PURPOSE:To report the outcomes of Boston keratoprosthesis (K-pro) type I implantation for congenital aniridia. METHODS:A retrospective review of the medical records of every patient with congenital aniridia who underwent Boston K-pro type I implantation at the University of Iowa Hospitals and Clinics from January 1, 2...

journal_title：Cornea

authors： Rixen JJ,Cohen AW,Kitzmann AS,Wagoner MD,Goins KM

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:Previous studies on the use of human amniotic membrane (HAM) in rabbit stem cell deficiency models have found the new epithelium growing over the HAM to express cornea-specific keratins (K3 and K12) in 40% of the cases, suggesting that HAM may have induced conjunctival epithelial cells to transdifferentiate int...

journal_title：Cornea

authors： Cho BJ,Djalilian AR,Obritsch WF,Matteson DM,Chan CC,Holland EJ

更新日期：1999-03-01 00:00:00

abstract：PURPOSE:Little research has been done on robotic ocular microsurgery. This study aims to demonstrate the feasibility of pterygium surgery using a robotic surgical system. METHODS:Robot-assisted pterygium surgery was performed on a 73-year-old patient with nasal and temporal pterygia using the DaVinci Si HD robotic Sur...

journal_title：Cornea

authors： Bourcier T,Chammas J,Becmeur PH,Danan J,Sauer A,Gaucher D,Liverneaux P,Mutter D

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:We report our experience in treating two cases of Scedosporium apiospermum keratitis and provide a review of basic scientific and clinical data regarding the treatment of this visually devastating disease. METHOD:We present a case report and literature review. RESULTS:A 35-year-old woman and a 73-year-old man...

journal_title：Cornea

authors： Wu Z,Ying H,Yiu S,Irvine J,Smith R

更新日期：2002-07-01 00:00:00

abstract：:The histological and ultrastructural pathology of two corneas that were removed from an infant with congenital glaucoma prior to keratoplasty is described. Clinically, the glaucoma was suspected to be due to an inapparent congenital viral infection, although there was no serological proof. Macroscopic and light micros...

journal_title：Cornea

authors： Löffler KU

更新日期：1991-01-01 00:00:00

abstract：PURPOSE:To determine how ocular surface epithelium adjusts to an increase in cell replication after treatment with the opioid antagonist naltrexone (NTX). METHODS:Adult male rats were given twice daily injections of 30 mg/kg NTX or vehicle for 7 days. Outcomes of NTX administration included DNA synthesis (monitored wi...

journal_title：Cornea

authors： Zagon IS,Sassani JW,McLaughlin PJ

更新日期：2006-08-01 00:00:00

abstract：PURPOSE:To study the corneal biocompatibility of bevacizumab on various cultured human corneal cells. METHODS:Cell cultures of corneal keratinocytes (CKs), corneal fibroblasts (CFs), and corneal endothelial cells (CECs) were harvested from human donor eyes and exposed to various concentrations of bevacizumab (0.25-5.0...

journal_title：Cornea

authors： Yoeruek E,Spitzer MS,Tatar O,Aisenbrey S,Bartz-Schmidt KU,Szurman P

更新日期：2007-09-01 00:00:00

abstract：PURPOSE:To evaluate sleep and mood status in patients with dry eye disease (DED) and analyze the association between sleep quality, mood status, and ocular surface characteristics. METHODS:Consecutive patients with DED (N = 106) and age- and sex-matched healthy controls (N = 50) were enrolled. Tear fluid break up time...

journal_title：Cornea

authors： Wu M,Liu X,Han J,Shao T,Wang Y

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:To describe the manual provocation test (MPT), a novel test for intermittent involutional entropion of the lower eyelid. METHODS:Retrospective review of patients with intermittent entropion who presented with ocular irritation and documented inward eyelid rotation by them or their referring physicians, but who...

journal_title：Cornea

authors： Tonk RS,Meyer DR

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:To report the clinical results of posterior lamellar keratoplasty (PLK) using predissected organ-cultured donor corneal tissue implanted after stripping of the Descemet membrane. METHODS:Twenty-two eyes of 22 patients in whom a PLK procedure was performed for pseudophakic bullous keratopathy and/or Fuchs endot...

journal_title：Cornea

authors： Nieuwendaal CP,Lapid-Gortzak R,van der Meulen IJ,Melles GJ

更新日期：2006-09-01 00:00:00

abstract：:We report a case of a patient with Down's syndrome and keratoconus with acute hydrops who was incidentally noted to have Axenfeld's anomaly. We also review the systemic abnormalities associated with Axenfeld's anomaly and the implications of the diagnosis. To our knowledge, Axenfeld's anomaly has not previously been r...

journal_title：Cornea

authors： Stokes DW,Parrish CM

更新日期：1992-03-01 00:00:00

abstract：PURPOSE:To review the incidence, distribution, current trends, and resistance patterns of bacterial keratitis isolates in Toronto over the past 16 years. METHODS:Microbiology records of suspected bacterial keratitis that underwent a diagnostic corneal scraping and cultures from January 1, 2000, through December 31, 20...

journal_title：Cornea

authors： Tam ALC,Côté E,Saldanha M,Lichtinger A,Slomovic AR

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of amniotic membrane in corneal ulcers refractive to conventional treatment and amniotic membrane with fibrin glue in corneal perforations. METHODS:Amniotic membrane transplantation (AMT) was performed in 33 eyes from 32 patients for corneal ulcers refractive to conventional treatment....

journal_title：Cornea

authors： Hick S,Demers PE,Brunette I,La C,Mabon M,Duchesne B

更新日期：2005-05-01 00:00:00

abstract：PURPOSE:To evaluate and compare 1-year postoperative visual acuity, refractive results, endothelial cell density (ECD), and complications in a consecutive group of patients who underwent deep lamellar endothelial keratoplasty (DLEK) with those who underwent penetrating keratoplasty (PK) performed by 1 surgeon. METHODS...

journal_title：Cornea

authors： Heidemann DG,Dunn SP,Chow CY

更新日期：2008-02-01 00:00:00

abstract：PURPOSE:To evaluate changes in the anterior chamber of eyes that have undergone Descemet membrane endothelial keratoplasty (DMEK) and to identify factors that affect these changes. METHODS:This retrospective study included 25 pseudophakic eyes of 25 patients who underwent DMEK. We determined the preoperative and posto...

journal_title：Cornea

authors： Onouchi H,Hayashi T,Shimizu T,Matsuzawa A,Suzuki Y,Kato N

更新日期：2020-09-29 00:00:00

abstract：PURPOSE:To describe bilateral microsporidial keratoconjunctivitis in healthy individuals with long-term follow-up. METHODS:Six cases of smear-positive bilateral microsporidial keratoconjunctivitis were diagnosed and followed up during the study period August 2017 to January 2019. Associated risk factors, clinical feat...

journal_title：Cornea

authors： Mohanty A,Mitra S,Das S,Priyadarshini S,Sahu SK

更新日期：2020-07-01 00:00:00

abstract：PURPOSE:To review the indications and patient characteristics for penetrating keratoplasty (PKP). METHODS:Retrospective review of records at the Pathology Service, Department of Ophthalmology, University of Toronto from 1964 to 1997. RESULTS:The 6,222 records were reviewed. The leading indications for PKP were regraf...

journal_title：Cornea

authors： Maeno A,Naor J,Lee HM,Hunter WS,Rootman DS

更新日期：2000-01-01 00:00:00

abstract：PURPOSE:To examine the role of epithelial cells in inducing the differentiation of keratocytes into myofibroblasts and to determine whether this effect may be inhibited by amniotic membrane matrix. METHODS:In vivo, a 9-mm diameter, partial-thickness corneal flap was created in 12 rabbit eyes (6 rabbits), which were eq...

journal_title：Cornea

authors： Choi TH,Tseng SC

更新日期：2001-03-01 00:00:00

abstract：PURPOSE:To compare the rebubbling rate and clinical outcomes of Descemet membrane endothelial keratoplasty (DMEK) with 5% sulfur hexafluoride (SF6) gas versus 100% air as a tamponade for graft attachment. METHODS:Retrospective, comparative, interventional case series including 368 consecutive pseudophakic eyes with Fu...

journal_title：Cornea

authors： Ampazas P,Droutsas K,Giallouros E,Schroeder FM,Sekundo W

更新日期：2017-10-01 00:00:00

abstract：PURPOSE:Tear secretion from the main lacrimal gland (LG) is mainly regulated by parasympathetic nerves. We performed several innervation studies to investigate lacrimation. METHODS:In male rabbits, we performed a retrograde dye-tracing study of LG innervation, evaluated preganglionic parasympathetic denervation, and a...

journal_title：Cornea

authors： Toshida H,Suto C

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:To report clinical outcome of treating ocular demodecosis by lid scrub with tea tree oil (TTO). METHODS:Retrospective review of clinical results in 11 patients with ocular Demodex who received weekly lid scrub with 50% TTO combined with daily lid hygiene with tea tree shampoo. RESULTS:These 11 patients also h...

journal_title：Cornea

authors： Gao YY,Di Pascuale MA,Elizondo A,Tseng SC

更新日期：2007-02-01 00:00:00

abstract：:Eleven patients with severe corneal disease have been operated with a collar-button-shaped keratoprosthesis and have been followed for 9-36 months. Two of the devices have been removed, but the remainder are securely in place. Six of the patients have benefitted substantially in terms of improved vision. The complicat...

journal_title：Cornea

authors： Dohlman CH,Doane MG

更新日期：1994-05-01 00:00:00

abstract：PURPOSE:We aimed to investigate the possible association of proteoglycans with D-periodic collagen fibrils in the human cornea and sclera, using energy-filtering transmission electron microscopy (EF-TEM) and atomic force microscopy (AFM). METHODS:Human cornea and sclera were digested with keratanase to eliminate kerat...

journal_title：Cornea

authors： Miyagawa A,Kobayashi M,Fujita Y,Hamdy O,Hirano K,Nakamura M,Miyake Y

更新日期：2001-08-01 00:00:00

abstract：PURPOSE:To report a case of conjunctival proliferation in a 2.5-year-old boy after initial evidence of a mild chemical injury after ocular exposure to pepper spray (oleoresin capsicum). METHODS:Case report with ophthalmologic and histologic findings. RESULTS:A child presented with mild conjunctival injection and chem...

journal_title：Cornea

authors： Gerber S,Frueh BE,Tappeiner C

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:To evaluate matrix metalloproteinases (MMP)-2, MMP-9, and tissue inhibitor of metalloproteinase (TIMP)-1 expression in a case of conjunctival intraepithelial squamous cell carcinoma (SCC) treated with topical 5-fluorouracil (5-FU) chemotherapy. METHODS:Clinicopathologic case report. RESULTS:A 71-year-old male...

journal_title：Cornea

authors： Iovieno A,Lambiase A,Moretti C,Perrella E,Bonini S

更新日期：2009-08-01 00:00:00

abstract：PURPOSE:To describe a surgical technique to achieve the desired plane during deep anterior lamellar keratoplasty (DALK) in eyes with Descemet membrane (DM) tears due to previous hydrops. METHODS:This was a prospective, consecutive, interventional case series of DALK in 12 keratoconic eyes with healed hydrops. Dissecti...

journal_title：Cornea

authors： Goweida MB,Sobhy M,Seifelnasr M,Liu C

更新日期：2019-04-01 00:00:00