Safety profile of bevacizumab on cultured human corneal cells.

abstract：PURPOSE:To compare the efficacy of topical cyclosporine [0.05% cyclosporine A (CsA)] and preservative-free artificial tears in the treatment of meibomian gland dysfunction (MGD). METHODS:A 3-month prospective, randomized, double-masked, parallel-group controlled trial enrolled 70 patients with symptomatic MGD and unst...

journal_title：Cornea

authors： Prabhasawat P,Tesavibul N,Mahawong W

更新日期：2012-12-01 00:00:00

abstract：:Spontaneous ruptures in Descemet's membrane in Terrien's degeneration can result in a corneal intralamellar pocket of fluid. We present a case and discuss its management. ...

journal_title：Cornea

authors： Romanchuk KG,Hamilton WK,Braig RF

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:To assess the effect of cataract surgery on semiautomated human corneal endothelial cell density (ECD) estimation using noncontact specular microscopy. METHODS:In this prospective clinical study, 62 consecutive patients undergoing cataract surgery were studied. To evaluate possible variations of accuracy and a...

journal_title：Cornea

authors： Wirbelauer C,Wollensak G,Pham DT

更新日期：2005-03-01 00:00:00

abstract：PURPOSE:To evaluate the effect of obstructive sleep apnea-hypopnea syndrome (OSAHS) on the meibomian glands, ocular surface, and tear parameters. METHODS:The study included 59 individuals (32 subjects with OSAHS, 27 control subjects) who underwent polysomnography in the Chest Diseases Clinic. The right eyes of all ind...

journal_title：Cornea

authors： Muhafiz E,Ölçen M,Erten R,Bozkurt E

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:Sequential therapeutic penetrating keratoplasty (TPK) using a cryopreserved cornea followed soon after by a fresh optical grade cornea for severe infectious keratitis may improve the survival of the optical graft. The aim of this study was to compare the therapeutic efficacy, visual outcomes, and graft survival...

journal_title：Cornea

authors： Lim LS,Arundhati A,Tan DT

更新日期：2011-07-01 00:00:00

abstract：PURPOSE:To describe a case of Beauveria bassiana keratitis and to discuss the management of this rare condition. METHODS:An 82-year-old woman underwent surgical repair of a graft wound dehiscence. Seven months later, shortly after the removal of sutures, the patient developed a fungal keratitis. B. bassiana was identi...

journal_title：Cornea

authors： Kisla TA,Cu-Unjieng A,Sigler L,Sugar J

更新日期：2000-05-01 00:00:00

abstract：PURPOSE:To report the first use of Descemet stripping automated endothelial keratoplasty (DSAEK) for spontaneous Descemet membrane detachment in a patient with osteogenesis imperfecta (OI), keratoconus, and acute bullous keratopathy. METHODS:A case report of a 25-year-old man with OI and symptomatic unilateral bullous...

journal_title：Cornea

authors： Gorovoy MS,Gorovoy IR,Ullman S,Gorovoy JB

更新日期：2012-07-01 00:00:00

abstract：:Two containers ("Iowa" and "Virginia") commonly used for transporting donor corneas, and various packing methods were evaluated for constancy of temperature maintenance. The larger Iowa container was found to be superior for extended storage. Packing methods that allowed the vials (containing McCarey-Kaufman medium) t...

journal_title：Cornea

authors： York KK,Ward DE,Smith RE

更新日期：1985-01-01 00:00:00

abstract：:The records of 39 patients undergoing 40 consecutive penetrating keratoplasties were reviewed to identify donor factors that might correlate with the presence of an epithelial defect on the first postoperative day. Of the 40 transplanted corneas, 13 (32.5%) had no epithelial defect, 18 (45%) had some epithelial defect...

journal_title：Cornea

authors： Kim T,Palay DA,Lynn M

更新日期：1996-09-01 00:00:00

abstract：PURPOSE:Ocular injuries after exposure to the vesicant sulfur mustard (SM) are characterized by acute corneal erosions and inflammation of the anterior segment that may be followed by delayed limbal stem cell deficiency (LSCD), expressed clinically by corneal neovascularization and epithelial defects. The present study...

journal_title：Cornea

authors： Kadar T,Dachir S,Cohen M,Gutman H,Cohen L,Brandeis R,Horwitz V,Amir A

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:To report risk factors, clinical course, and outcome in patients with infectious keratitis following implantation of intracorneal ring segments (ICRS). METHODS:The records of 8 patients with culture-proven infectious keratitis after ICRS (Ferrara or Intacs) implantation were retrospectively reviewed. Age, gend...

journal_title：Cornea

authors： Hofling-Lima AL,Branco BC,Romano AC,Campos MQ,Moreira H,Miranda D,Kwitko S,de Freitas D,Casanova FH,Sartori M,Schor P,Souza LB

更新日期：2004-08-01 00:00:00

abstract：PURPOSE:To report the use of excimer laser phototherapeutic keratectomy (PTK) in the treatment of corneal subepithelial nodular scarring in a child with Rothmund-Thomson syndrome (RTS), a form of ectodermal dysplasia. METHODS:A case report and review of the literature. RESULTS:Excimer laser PTK successfully treated t...

journal_title：Cornea

authors： Stahl J,Fulcher S,Berkeley R

更新日期：2000-01-01 00:00:00

abstract：:The many published studies on sterile procedures used by eye banks have included none until now on ways to optimize sterile handling of corneas procured in the morgues of forensic pathologists. The present study sought to discover if fewer positive cultures would be reported at the time of surgery from corneas which h...

journal_title：Cornea

authors： Farge EJ,Fort RA

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:To investigate the pachymetric changes of collagen cross-linking in corneas with edema because of endothelial dysfunction. METHODS:Interventional case series included 25 eyes of 25 consecutive patients with corneal edema for at least 4 months related to Fuchs endothelial dystrophy, corneal graft failure, and p...

journal_title：Cornea

authors： Cordeiro Barbosa MM,Barbosa JB Jr,Hirai FE,Hofling-Lima AL

更新日期：2010-06-01 00:00:00

abstract：:Absorbable intracanalicular collagen implants were placed in both canaliculi of one eye of nine human volunteers. The other eye served as a control. Twenty-four hours later 2% sodium fluorescein was placed into both conjunctival sacs. Serial corneal fluorescein concentrations were measured with a scanning ocular fluor...

journal_title：Cornea

authors： Unterman SR,Reidy JJ,Hill JH,Kaufman HE

更新日期：1991-11-01 00:00:00

abstract：PURPOSE:To develop a rat model of chronic Acanthamoeba polyphaga keratitis suitable for pharmacologic assessment of therapeutic agents. METHODS:An A. polyphaga isolate (ATCC #50495) was grown in peptone-yeast extract-glucose medium. Five-weeks-old, Sprague-Dawley male rats were injected with 10(3) or 10(4) trophozoite...

journal_title：Cornea

authors： Vasseneix C,Gargala G,François A,Hellot MF,Duclos C,Muraine M,Benichou J,Ballet JJ,Brasseur G,Favennec L

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:To determine the prevalence of herpes simplex virus type 1 (HSV-1) DNA in failed Descemet membrane stripping automated endothelial keratoplasty (DSAEK) grafts. METHODS:A retrospective interventional case series of patients with DSAEK graft failure treated at the New York Eye and Ear Infirmary between January 2...

journal_title：Cornea

authors： Yin D,Huang A,Warrow D,Ritterband DC,Seedor JA,McCormick SA,Milman T

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:The 27-kDa heat shock protein (HSP27) has been implicated in wound healing in multiple tissues. We investigated the expression and localization of phosphorylated HSP27 during epithelial wound healing in the murine cornea. METHODS:Corneas of 8- to 10-week-old C57BL6 mice were wounded by epithelial debridement (...

journal_title：Cornea

authors： Jain S,De la Cruz J,Kang E,Kojima T,Chang JH,Kim JY

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:The aim of this study was to describe the clinical features of infectious scleritis with distinct inciting events and to analyze the factors associated with poor visual outcome. METHODS:We retrospectively reviewed the predisposing factors, clinical findings, isolated organisms, complications, and outcomes of p...

journal_title：Cornea

authors： Ho YF,Yeh LK,Tan HY,Chen HC,Chen YF,Lin HC,Chen SY,Hui-Kang D,Hsiao CH

更新日期：2014-08-01 00:00:00

abstract：:The introduction of the excimer laser for keratorefractive surgery in the 1990 s permanently reshaped the treatment landscape for correcting refractive errors, such as myopia, hyperopia, and astigmatism. Until that point, these treatments had relied on less predictable techniques, such as radial keratotomy and automat...

journal_title：Cornea

authors： Azar DT,Chang JH,Han KY

更新日期：2012-11-01 00:00:00

abstract：PURPOSE:To investigate the in vivo, corneal, biomechanical changes after corneal collagen cross-linking (CXL) using the Ocular Response Analyzer (ORA) in patients with keratoconus and post-laser in situ keratomileusis (LASIK) ectasia. METHODS:Single-center, prospective, randomized, controlled, clinical trial. After CX...

journal_title：Cornea

authors： Greenstein SA,Fry KL,Hersh PS

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To describe the effect of the corneal asphericity and toricity on the map patterns and best fit sphere (BFS) characteristics in elevation topography. METHODS:The corneal surface was modeled as a biconic surface of principal radii and asphericity values of r1 and r2 and Q1 and Q2, respectively. The apex of the ...

journal_title：Cornea

authors： Gatinel D,Malet J,Hoang-Xuan T,Azar DT

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:To evaluate the long-term changes in anterior and posterior corneal irregular astigmatism and curvatures after small incision lenticule extraction (SMILE). METHODS:Fifty eyes of 28 patients underwent SMILE for myopic astigmatism. All procedures were performed using the VisuMax® femtosecond laser. A Scheimpflug...

journal_title：Cornea

authors： Sideroudi H,Lazaridis A,Messerschmidt-Roth A,Labiris G,Kozobolis V,Sekundo W

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:We studied the possibility that tranilast, an antiallergic and antiproliferative drug, may be beneficial for the treatment of pterygium. METHODS:Pterygium-derived cells were identified by immunohistochemical methods. Growth rate of pterygium-derived cells was determined by using a hemocytometer. Chemotaxis was...

journal_title：Cornea

authors： Isaji M,Kikuchi S,Miyata H,Ajisawa Y,Araki-Inazawa K,Tsukamoto Y,Amano Y

更新日期：2000-05-01 00:00:00

abstract：PURPOSE:To report the diagnosis and management of a patient with a well-tolerated, long-standing retained intracorneal foreign body. METHODS:We describe the case of a 62-year-old man with a 40-year-old retained wood foreign body within the posterior stroma of the cornea. To the authors' knowledge, this is the longest ...

journal_title：Cornea

authors： Covert DJ,Henry CR,Sheth BP

更新日期：2009-06-01 00:00:00

abstract：PURPOSE:To compare optical low-coherence reflectometry (OLCR) and ultrasound pachymetry in measuring corneal graft thickness in patients after keratoplasty. METHODS:We retrospectively measured the central graft thickness in 41 eyes of 41 patients with the OLCR pachymeter (Haag Streit, Koeniz, Switzerland) and the SP-2...

journal_title：Cornea

authors： Gaujoux T,Borderie VM,Yousfi H,Bourcier T,Touzeau O,Laroche L

更新日期：2007-02-01 00:00:00

abstract：PURPOSE:To compare the rate of epithelial healing of corneal erosion in an animal model with 2 commercial formulations of fourth-generation fluoroquinolones: 0.3% gatifloxacin and 0.5% moxifloxacin. METHODS:Corneal erosions, 6 mm in diameter, were created in 28 rabbit eyes. The rabbits were randomized to receive topic...

journal_title：Cornea

authors： Barequet IS,Habot-Wilner Z,Lavinsky F,Ziv H,Belkin M,Rosner M

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:To investigate the surgical procedure and therapeutic efficacy of femtosecond (FS) laser-assisted keratolimbal allograft (KLAL) transplantation in the treatment of eyes with total limbal stem cell deficiency. METHODS:Ten eyes from 10 patients who underwent FS laser-assisted KLAL transplantation were enrolled. ...

journal_title：Cornea

authors： Qi X,Duan F,Li X,Zhang X,Li N,Liu M,Gao H

更新日期：2019-10-01 00:00:00

abstract：PURPOSE:Little research has been done on robotic ocular microsurgery. This study aims to demonstrate the feasibility of pterygium surgery using a robotic surgical system. METHODS:Robot-assisted pterygium surgery was performed on a 73-year-old patient with nasal and temporal pterygia using the DaVinci Si HD robotic Sur...

journal_title：Cornea

authors： Bourcier T,Chammas J,Becmeur PH,Danan J,Sauer A,Gaucher D,Liverneaux P,Mutter D

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:The purpose of this case series was to evaluate the effectiveness of modified deep anterior lamellar keratoplasty in eyes with scarring secondary to hydrops associated with keratoconus. METHODS:Four patients underwent modified deep anterior lamellar keratoplasty. This was performed by controlled air injection ...

journal_title：Cornea

authors： Ramamurthi S,Ramaesh K

更新日期：2011-02-01 00:00:00