Corneal subepithelial nodular scarring treated with phototherapeutic keratectomy in a child with Rothmund-Thomson syndrome.

abstract：PURPOSE:To investigate the regulation of matrix metalloproteinase (MMP)-3 and MMP-13 expression over time and in the presence of cyclosporine A (CsA) in primary cultured human pterygium fibroblasts. We also examined the effects of CsA on cultured human pterygium fibroblasts. METHODS:Primary cultured human pterygium fi...

journal_title：Cornea

authors： Kim YH,Jung JC,Jung SY,Kim YI,Lee KW,Park YJ

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:To investigate the in vivo, corneal, biomechanical changes after corneal collagen cross-linking (CXL) using the Ocular Response Analyzer (ORA) in patients with keratoconus and post-laser in situ keratomileusis (LASIK) ectasia. METHODS:Single-center, prospective, randomized, controlled, clinical trial. After CX...

journal_title：Cornea

authors： Greenstein SA,Fry KL,Hersh PS

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To report the outcome and the reversibility of refractive outcomes after intrastromal corneal ring segment (ICRS) explantation in patients with keratoconus treated with ICRS implantation and same-day collagen crosslinking (CXL). METHODS:This is a retrospective review of ICRS explantation in 3 eyes of 3 patient...

journal_title：Cornea

authors： Yeung SN,Lichtinger A,Ku JY,Kim P,Low SA,Rootman DS

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:To evaluate the effect of subconjunctival injection of suramin on corneal neovascularization in rabbits. METHODS:Corneal neovascularization was induced by silk suturing of the corneal stroma in 40 eyes of 40 male New Zealand white rabbits. Five days after suture placement, all rabbits were randomly divided int...

journal_title：Cornea

authors： Lee HS,Chung SK

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:To compare the corneal and aqueous penetration and pharmacokinetics of gatifloxacin 0.3% and moxifloxacin 0.5% ophthalmic solutions and their effect on corneal reepithelialization after penetrating keratoplasty. METHODS:In this randomized, open-label, parallel-controlled study, corneal and aqueous penetration ...

journal_title：Cornea

authors： Holland EJ,Lane SS,Kim T,Raizman M,Dunn S

更新日期：2008-04-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the antiangiogenic activity of AU6, a novel 6-amino acid peptide derived from Kringle V of human apolipoprotein (a). METHODS:RF/6A rhesus macaque choroid endothelial cells were used for in vitro studies. MTS [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sul...

journal_title：Cornea

authors： Wang Z,Zhao H,Ma JX,Xu X

更新日期：2014-04-01 00:00:00

abstract：PURPOSE:To report a case of keratitis and corneal melt after conductive keratoplasty (CK) enhancement. METHOD:Case report. RESULTS:A 52-year-old woman with emmetropic presbyopia had undergone previous CK for monovision and underwent CK enhancement 4 years later. Postoperatively, she was managed with ketorolac trometh...

journal_title：Cornea

authors： Khalifa YM,Mifflin MD

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:To report a case of intraocular lens (IOL) exchange performed 1 week after Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS:Describe the clinical findings and outcome of IOL exchange in an 80-year-old man with pseudophakic bullous keratopathy and retained Artisan (Ophtec BV, Groningen, th...

journal_title：Cornea

authors： Lapenna L,Kadyan A,Busin M

更新日期：2010-02-01 00:00:00

abstract：PURPOSE:To evaluate the results of a combined approach of cicatrix lysis, intraoperative mitomycin C (MMC) application, oral mucosal transplantation (OMT), and amniotic membrane transplantation (AMT) for surgery of severe symblepharon. METHODS:This prospective study included 32 eyes with severe symblepharon in which a...

journal_title：Cornea

authors： Kheirkhah A,Ghaffari R,Kaghazkanani R,Hashemi H,Behrouz MJ,Raju VK

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:To evaluate the histologic changes in corneal structure after femtosecond laser preparation of posterior lamellar discs, more specifically, the smoothness of the stromal bed and the accuracy of the predicted depth of the horizontal lamellar cut. MATERIALS AND METHODS:Nineteen human donor eyes unsuitable for tr...

journal_title：Cornea

authors： Cheng YY,Kang SJ,Grossniklaus HE,Pels E,Duimel HJ,Frederik PM,Hendrikse F,Nuijts RM

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:To assess ultrastructural modifications in keratocytes and inflammatory cell response in rabbit corneas after riboflavin and ultraviolet A exposure using immunofluorescence microscopy. METHODS:Twenty adult New Zealand albino rabbits weighing 2.0–3.0 kg were used in this study. Two rabbits served as controls.Th...

journal_title：Cornea

authors： Esquenazi S,He J,Li N,Bazan HE

更新日期：2010-04-01 00:00:00

abstract：:The pharmacokinetics and toxicity of subconjunctival (S/C) amphotericin B (AmB) were evaluated in Dutch-belted rabbits. Following the S/C injection of 1,500 micrograms of AmB, corneal and aqueous levels were determined by bioassay. The highest levels were present in the periphery of debrided corneas at 1 h (90.12 +/- ...

journal_title：Cornea

authors： O'Day DM,Smith R,Stevens JB,Williams TE,Robinson RD,Head WS

更新日期：1991-09-01 00:00:00

abstract：OBJECTIVES:To evaluate the efficacy of systemic or topical administration of cyclosporin A (CsA) after limbal transplantation of stem cell allografts in rabbits. METHODS:Thirty-six rabbits underwent corneal epithelial debridement and limbal ablation to induce ocular surface disease and were then treated by limbal allo...

journal_title：Cornea

authors： Xu KP,Wu Y,Zhou J,Zhang X

更新日期：1999-07-01 00:00:00

abstract：:Decompensation of the corneal endothelium causes severe visual impairments that lead to blindness. Although corneal transplantation is a well-known effective therapy for corneal endothelial dysfunction, many patients are not afforded that therapeutic opportunity owing to the worldwide shortage of donor corneas. Thus, ...

journal_title：Cornea

authors： Okumura N,Kinoshita S,Koizumi N

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy of Dermabond with conventional nylon sutures for sealing linear corneal incisions. METHODS:A keratome knife was used to create a 4-mm full-thickness linear corneal incision anterior to the limbal arcade in 20 fresh pig eyes. The incision was sealed with Dermabond tissue adhesive or cl...

journal_title：Cornea

authors： Leung GY,Peponis V,Varnell ED,Lam DS,Kaufman HE

更新日期：2005-11-01 00:00:00

abstract：PURPOSE:To compare higher-order aberrations (HOAs) after small incision lenticule extraction (SMILE) in patients with and without intraoperative angle kappa adjustments. METHODS:This is a retrospective case series. One hundred six eyes of 106 patients who underwent SMILE at Tianjin Eye Hospital (Tianjin Medical Univer...

journal_title：Cornea

authors： Shao T,Wang Y,Ng ALK,Chan TCY,Hao W,Zhang J,Cheng GPM,Jhanji V

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:To study the predisposing conditions, treatments, and visual outcomes of nontraumatic corneal perforations. METHODS:A retrospective chart review was conducted of all nontraumatic corneal perforations seen between January 1992 and December 1998, with > or = 3 months of follow-up, at the Cornea Service Wills Eye...

journal_title：Cornea

authors： Lekskul M,Fracht HU,Cohen EJ,Rapuano CJ,Laibson PR

更新日期：2000-05-01 00:00:00

abstract：PURPOSE:Endogenous hyaluronan (HA) has previously been shown to be a part of corneal wound healing after photorefractive keratectomy (PRK). HA is known to bind considerable amounts of water. This study aimed to show whether HA colocalized with water in the wound area after PRK. METHODS:Five New Zealand White rabbits w...

journal_title：Cornea

authors： Weber BA,Fagerholm P,Johansson B

更新日期：1997-09-01 00:00:00

abstract：PURPOSE:The goal of this study was to prospectively assess the deep lamellar endothelial keratoplasty (DLEK) wound anatomy and its evolution during the 12 months after surgery, using optical coherence tomography (OCT). METHODS:The eyes of 8 patients (1 eye per patient) who consecutively underwent DLEK for Fuchs dystro...

journal_title：Cornea

authors： Ferré LA,Nada O,Sherknies D,Boisjoly H,Brunette I

更新日期：2010-07-01 00:00:00

abstract：PURPOSE:Patients undergoing primary pterygium excision with autologous conjunctival autograft and human tissue adhesive in New Zealand, currently receive subconjunctival anesthesia with oral postoperative analgesia for pain. Our aim was to investigate the potential added benefit of intraoperative subtenon bupivacaine t...

journal_title：Cornea

authors： Bhikoo R,Hughes K,Vather R,Murphy C

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:The normal cornea is devoid of blood and lymphatic vessels but can become vascularized secondary to a variety of corneal diseases and surgical manipulations. Whereas corneal (hem)angiogenesis, i.e., the outgrowth of new blood vessels from preexisting limbal vessels, is obvious both clinically and histologically...

journal_title：Cornea

authors： Cursiefen C,Chen L,Dana MR,Streilein JW

更新日期：2003-04-01 00:00:00

abstract：PURPOSE:To evaluate the accuracy and precision of corneal flap thickness following laser in situ keratomileusis (LASIK) performed using the 140-, 160-, and 180-microm heads for the Amadeus microkeratome (AMO, Irvine, CA). SETTING:The study took place at the Cullen Eye Institute, Baylor College of Medicine, Houston. M...

journal_title：Cornea

authors： Jackson DW,Wang L,Koch DD

更新日期：2003-08-01 00:00:00

abstract：PURPOSE:To review ocular injuries secondary to airbag deployment that were seen in our institution and were reported in the literature. METHODS:Patients examined at our institution between 1997 and 2000 were evaluated for ocular injuries caused by airbags. A review of the medical literature using Medline was performed...

journal_title：Cornea

authors： Ball DC,Bouchard CS

更新日期：2001-03-01 00:00:00

abstract：PURPOSE:To analyze tear meniscus dimensions with Fourier domain-optical coherence tomography (FD-OCT) in patients with type 2 diabetes mellitus. METHODS:Patients with type 2 diabetes without diabetic retinopathy (DR) (n = 54), with nonproliferative DR (n = 45), with proliferative DR (PDR) (n = 25), and controls (n = 4...

journal_title：Cornea

authors： Baek J,Doh SH,Chung SK

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:To examine the effect of successful repositioning/rebubbling of the graft on endothelial cell counts (ECCs) in eyes after Descemet stripping automated endothelial keratoplasty. METHODS:This retrospective study reviewed the outcomes of 58 eyes that underwent Descemet stripping automated endothelial keratoplasty...

journal_title：Cornea

authors： Mashor RS,Kaiserman I,Kumar N,Sansanayudh W,Rootman D

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:This study was designed to identify factors that predict longitudinal increases in corneal curvature as measured by the First Definite Apical Clearance Lens (FDACL) and flatter keratometric reading (Flat K) in keratoconus. METHODS:The Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study is a long-...

journal_title：Cornea

authors： McMahon TT,Edrington TB,Szczotka-Flynn L,Olafsson HE,Davis LJ,Schechtman KB,CLEK Study Group.

更新日期：2006-04-01 00:00:00

abstract：PURPOSE:To describe a distinct and unusual superficial dendriform keratopathy that can be seen in postkeratoplasty eyes. METHOD:Three Caucasian women in their sixth decade of life were referred to the Corneal and External Disease Service at the University of California, Davis, and underwent penetrating keratoplasty fo...

journal_title：Cornea

authors： Mannis MJ,Garcia-Ferrer FJ,Davitt S

更新日期：1998-05-01 00:00:00

abstract：PURPOSE:To review our previous studies regarding the morphology of the cornea in pseudoexfoliation syndrome (PEX) and anatomical discrepancies between PEX and contralateral eyes in unilateral PEX. METHODS:We used in vivo confocal microscopy to observe the corneas of PEX, contralateral, and normal control eyes. Morphol...

journal_title：Cornea

authors： Zheng X

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:To measure the refractive index (RI) of the human corneal stroma in vivo using an objective Abbé refractometer (VCH-1) and to determine if RI of the stroma is related to age. METHODS:The VCH-1 was calibrated against a standard subjective Abbé refractometer using 7 randomly selected turbid semiliquid media. VCH...

journal_title：Cornea

authors： Patel S,Alió JL,Amparo F,Rodriguez-Prats JL

更新日期：2011-12-01 00:00:00

abstract：PURPOSE:To describe the management of three cases of corneal perforation associated with silicone oil in the anterior chamber. METHODS:Review of 3 case records. RESULTS:Three cases of perforation associated with silicone oil in the anterior chamber are reviewed. One patient required gluing and a bandage contact lens,...

journal_title：Cornea

authors： Ghosheh FR,Rapuano CJ

更新日期：2007-10-01 00:00:00