Histologic evaluation of human posterior lamellar discs for femtosecond laser Descemet's stripping endothelial keratoplasty.

abstract：:Corneal neovascularization complicates many anterior segment diseases. Corneal laser photocoagulation using yellow light (577 nm) has been shown to reduce corneal neovascularization. No histopathologic studies of the effects of this treatment on the eye have been reported, however. Target (cornea) and nontarget (iris,...

journal_title：Cornea

authors： Hemady RK,Baer JC,Foster CS

更新日期：1993-05-01 00:00:00

abstract：PURPOSE:Ocular local anesthetics currently used in routine clinical practice for corneal anesthesia are short acting and their ability to delay corneal healing makes them unsuitable for long-term use. In this study, we examined the effect of the site 1 sodium channel blocker tetrodotoxin (TTX) on the duration of cornea...

journal_title：Cornea

authors： Wang L,Shankarappa SA,Tong R,Ciolino JB,Tsui JH,Chiang HH,Kohane DS

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:The p63 gene has been identified as a marker of epithelial stem cells. Because pterygium may arise through an expansion of the proliferative capacity of the conjunctiva, we sought to document the expression of p63 in normal conjunctiva and pterygium specimens. METHODS:Immunostaining for p63 expression was perf...

journal_title：Cornea

authors： Sakoonwatanyoo P,Tan DT,Smith DR

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:Comparative evaluation of efficacy of monotherapy with moxifloxacin (0.5%) or gatifloxacin (0.3%) with combination therapy of cefazolin (5%) and tobramycin (1.3%) in treatment of bacterial corneal ulcers. METHODS:Patients diagnosed with bacterial keratitis (ulcer diameter 2-8 mm) were randomized to 1 of the 3 ...

journal_title：Cornea

authors： Shah VM,Tandon R,Satpathy G,Nayak N,Chawla B,Agarwal T,Sharma N,Titiyal JS,Vajpayee RB

更新日期：2010-07-01 00:00:00

abstract：PURPOSE:To assess the effects of corneal collagen cross-linking (CXL) on contrast sensitivity (CS), visual acuity, and corneal topography investigating possible predictors of efficacy. METHODS:Sixty-eight eyes of 34 patients with progressive keratoconus were enrolled in this prospective study. CXL was performed in one...

journal_title：Cornea

authors： Lamy R,Netto CF,Reis RG,Procopio B,Porco TC,Stewart JM,Dantas AM,Moraes HV Jr

更新日期：2013-05-01 00:00:00

abstract：:Epithelium plays a very important structural and functional role in the cornea and conjunctiva. Evaluation of the epithelium is the first step in diagnosing many pathologic states. We have developed a new technique for the in vivo staining of nuclei of corneal and conjunctival epithelium in rabbits and guinea pigs. Se...

journal_title：Cornea

authors： Wander AH,Neumeister RD,Tschismadia I,Choromokos EA,Masukawa T

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:To study the predisposing conditions, treatments, and visual outcomes of nontraumatic corneal perforations. METHODS:A retrospective chart review was conducted of all nontraumatic corneal perforations seen between January 1992 and December 1998, with > or = 3 months of follow-up, at the Cornea Service Wills Eye...

journal_title：Cornea

authors： Lekskul M,Fracht HU,Cohen EJ,Rapuano CJ,Laibson PR

更新日期：2000-05-01 00:00:00

abstract：PURPOSE:To report a case of epithelial ingrowth (downgrowth) occurring in a phakic corneal transplant patient after traumatic wound dehiscence with iris prolapse that was successfully eradicated with early surgical intervention. METHODS:Interventional case report of a 70-year-old monocular, phakic patient who develope...

journal_title：Cornea

authors： Nagra PK,Raber IM

更新日期：2003-03-01 00:00:00

abstract：:Persistent donor corneal epithelial defects following penetrating keratoplasty may lead to graft failure. We herein describe a method for providing corneal protection using a temporary suture tarsorrhaphy. This technique is simple and completely reversible, and it allows continued observation and instillation of topic...

journal_title：Cornea

authors： Koenig SB,Harris GJ

更新日期：1991-03-01 00:00:00

abstract：PURPOSE:This study was designed to identify factors that predict longitudinal increases in corneal curvature as measured by the First Definite Apical Clearance Lens (FDACL) and flatter keratometric reading (Flat K) in keratoconus. METHODS:The Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study is a long-...

journal_title：Cornea

authors： McMahon TT,Edrington TB,Szczotka-Flynn L,Olafsson HE,Davis LJ,Schechtman KB,CLEK Study Group.

更新日期：2006-04-01 00:00:00

abstract：PURPOSE:To compare the process of conjunctival epithelial regeneration after three types of pterygium excision procedures. METHODS:Thirty-eight patients (45 eyes) with primary pterygium were randomly assigned to a bare-sclera procedure (group 1, 15 eyes of 12 patients), bare-sclera with intraoperative mitomycin C (MMC...

journal_title：Cornea

authors： Tseng SH,Chen YT,Cheng HC,Huang FC,Lee SC,Chen FK

更新日期：2001-04-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the visual function information obtained from multiple reading tests in a dry eye population. METHODS:In this case-control, single-center clinical research center-based study, 15 subjects with dry eye (mean age 65 years) and 10 normal subjects (mean age 40 years) were incl...

journal_title：Cornea

authors： Ousler GW 3rd,Rodriguez JD,Smith LM,Lane KJ,Heckley C,Angjeli E,Abelson MB

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:To describe the clinical characteristics, diagnosis, treatment, and visual outcome of 61 cases of Fusarium keratitis in Mexico. METHODS:Retrospective, comparative study of 61 patients with clinically and culture-confirmed Fusarium keratitis, who were attended at an eye hospital in Mexico City from 1981 to 2001...

journal_title：Cornea

authors： Pérez-Balbuena AL,Vanzzini-Rosano V,Valadéz-Virgen Jde J,Campos-Möller X

更新日期：2009-07-01 00:00:00

abstract：:Absorbable intracanalicular collagen implants were placed in both canaliculi of one eye of nine human volunteers. The other eye served as a control. Twenty-four hours later 2% sodium fluorescein was placed into both conjunctival sacs. Serial corneal fluorescein concentrations were measured with a scanning ocular fluor...

journal_title：Cornea

authors： Unterman SR,Reidy JJ,Hill JH,Kaufman HE

更新日期：1991-11-01 00:00:00

abstract：PURPOSE:To investigate the changes of meibomian gland (MG) and tear film stability in subjects with eyelid tattoos. METHODS:Forty female subjects were recruited. Ten subjects had eyelid tattoos and 30 subjects did not (control group). Tear film break-up time (TBUT) measurement and fluorescein staining were performed t...

journal_title：Cornea

authors： Lee YB,Kim JJ,Hyon JY,Wee WR,Shin YJ

更新日期：2015-07-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of superficial keratectomy and conjunctival advancement hood flap (SKCAHF) for the treatment of bullous keratopathy in canine patients. METHODS:Nine dogs (12 eyes) diagnosed with progressive corneal edema underwent superficial keratectomy followed by placement of conjunctival advanceme...

journal_title：Cornea

authors： Horikawa T,Thomasy SM,Stanley AA,Calderon AS,Li J,Linton LL,Murphy CJ

更新日期：2016-10-01 00:00:00

abstract：:To compare the efficacy of ciprofloxacin hydrochloride ointment with that of ciprofloxacin drops for treatment of experimental Pseudomonas keratitis, rabbit eyes were infected by intrastromal injection of 10(3) colony-forming units (CFU) log-phase P. aeruginosa. Infected and uninfected eyes were treated with either 0....

journal_title：Cornea

authors： Hobden JA,O'Callaghan RJ,Insler MS,Hill JM

更新日期：1993-03-01 00:00:00

abstract：PURPOSE:To describe the histopathologic characteristics of a 51-year-old Castroviejo square graft that remained functional for more than 50 years and to describe the wound-healing characteristics over this period of time. METHODS:An 80-year-old woman with a history of keratoconus underwent penetrating keratoplasty wit...

journal_title：Cornea

authors： Graue-Hernández EO,Harocopos G,Bradley JC,Smith ME,Mannis MJ

更新日期：2009-04-01 00:00:00

abstract：:Penetrating keratoplasty (PKP) in conjunction with postoperative corticosteroids may reactivate latent herpes simplex virus type 1 (HSV-1) to cause persistent postoperative epithelial defects. The clinical diagnosis of HSV keratitis after penetrating keratoplasty is difficult because the postoperative appearance may b...

journal_title：Cornea

authors： Portnoy SL,Beyer CF,Hill JM,Kaufman HE

更新日期：1991-01-01 00:00:00

abstract：:Two patients developed graft versus host disease (GvHD) following allogeneic bone marrow transplantation for leukemia. One patient developed acute GvHD 12 days after transplantation, and the second developed chronic GvHD 100 days after transplantation. Tear analysis and conjunctival impression cytology were performed....

journal_title：Cornea

authors： Heitman KF,Lam KW,Maskin SL,Yee RW,Lawton AW

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:Descemet stripping endothelial keratoplasty (DSEK), currently the most common procedure for managing corneal endothelial dysfunction, may be repeated following DSEK failure from a variety of causes. This multicenter study reports the risk factors and outcomes of repeat DSEK. METHODS:This was an institutional r...

journal_title：Cornea

authors： Thompson JM,Truong AH,Stern HD,Djalilian A,Cortina MS,Tu EY,Johnson P,Verdier DD,Rafol L,Lubeck D,Spektor T,Jorgensen C,Rubenstein JB,Majmudar PA,Talati R,Basti S,Feder R,Sugar A,Mian SI,Balasubramanian N,Sandhu J

更新日期：2019-02-01 00:00:00

abstract：PURPOSE:To assess the effect of cataract surgery on semiautomated human corneal endothelial cell density (ECD) estimation using noncontact specular microscopy. METHODS:In this prospective clinical study, 62 consecutive patients undergoing cataract surgery were studied. To evaluate possible variations of accuracy and a...

journal_title：Cornea

authors： Wirbelauer C,Wollensak G,Pham DT

更新日期：2005-03-01 00:00:00

abstract：:The present study describes biochemical and morphological differences of pseudophakic bullous keratopathy (PBK) corneas as compared with normal corneas. At the ultrastructural level, all PBK corneas studied had abnormal fibrillar material posterior to the Descemet's membrane. In addition, two of the six PBK buttons ha...

journal_title：Cornea

authors： Kenney MC,Chwa M

更新日期：1990-04-01 00:00:00

abstract：:In order to evaluate the effect of a commonly used sodium hyaluronate preparation (Healon, Pharmacia AB, Uppsala, Sweden) on the incidence of endothelial rejection, endothelial cell loss, intraocular pressure, and corneal thickness after penetrating keratoplasty, we conducted a randomized clinical trial. Patients were...

journal_title：Cornea

authors： Musch DC,Meyer RF,Sugar A,Soong HK

更新日期：1990-10-01 00:00:00

abstract：PURPOSE:In humans, loss-of-function mutations in the gene encoding Chordin-like 1 (CHRDL1) cause X-linked megalocornea (MGC1), characterized by bilateral corneal enlargement, decreased corneal thickness, and increased anterior chamber depth (ACD). We sought to determine whether Chrdl1 knockout (KO) mice would recapitul...

journal_title：Cornea

authors： Chen D,Liu Y,Shu G,Chen C,Sullivan DA,Kam WR,Hann S,Fowler M,Warman ML

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:Evaluation of contact lens-induced cytologic changes on the conjunctival surface. METHODS:Fifty eyes of 25 patients wearing soft or rigid gas-permeable contact lenses, and 50 healthy eyes of 25 control subjects were examined with conjunctival impression cytology. Of the patients wearing contact lenses, 40% did...

journal_title：Cornea

authors： Adar S,Kanpolat A,Sürücü S,Ucakhan OO

更新日期：1997-05-01 00:00:00

abstract：:Human type IV collagen discs were found to support proliferation and adhesion of rabbit corneal epithelial cells in tissue culture. To assess the biocompatibility of this synthetic collagen for epikeratoplasty, seven eyes of seven rhesus monkeys underwent epikeratoplasty with lenticules made of human type IV collagen....

journal_title：Cornea

authors： Thompson KP,Hanna KD,Gipson IK,Gravagna P,Waring GO 3rd,Johnson-Wint B

更新日期：1993-01-01 00:00:00

abstract：PURPOSE:In a Strampelli osteo-odonto-keratoprosthesis, a patch of oral mucosa is frequently used to cover the ocular surface after implantation of an osteodental lamina into the eye. In many cases, gross modifications in the eye covering become apparent a few years later. The aim of this study was to investigate the hi...

journal_title：Cornea

authors： Pecorella I,Maurizio T,Antonio C,Giancarlo F

更新日期：2006-02-01 00:00:00

abstract：:Epithelialization of uveal structures is frequently difficult to diagnose clinically and may require scanning and/or transmission electron microscopy to detect histologically. Since the scanning and transmission electron microscopic findings of progressive iris epithelialization have not previously been described, we ...

journal_title：Cornea

authors： Burris TE,Nordquist RE,Rowsey JJ

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:To evaluate the changes and trends in the number and characteristics of contact lens-related ulcers (CLRUs) and to compare the results with those of previously published series at our institution. METHODS:Medical records of all patients diagnosed with presumed bacterial corneal ulcers seen at the Cornea Servic...

journal_title：Cornea

authors： Yildiz EH,Airiani S,Hammersmith KM,Rapuano CJ,Laibson PR,Virdi AS,Hongyok T,Cohen EJ

更新日期：2012-10-01 00:00:00