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The effect of successful rebubbling after descemet stripping automated endothelial keratoplasty on endothelial cell counts.

Abstract：

PURPOSE:To examine the effect of successful repositioning/rebubbling of the graft on endothelial cell counts (ECCs) in eyes after Descemet stripping automated endothelial keratoplasty. METHODS:This retrospective study reviewed the outcomes of 58 eyes that underwent Descemet stripping automated endothelial keratoplasty. Fifty-one eyes were attached after surgery. Seven were detached and underwent rebubbling with minimal manipulation in 5 and significant manipulation in 2, after which the graft was attached and clear. Visual outcomes and endothelial cell loss at 6 months were compared between eyes that underwent repositioning/rebubbling and those that did not. The following were excluded: 2 eyes that had primary failure, 2 eyes that had rejection, 1 eye that failed to attach after rebubbling, 2 eyes that failed to clear after rebubbling, and 24 eyes that did not have ECC at 6 months. RESULTS:The 2 groups were comparable considering age, preoperative best-corrected visual acuity, surgical variables, combined procedures, donor cell count, and graft size. The mean postoperative spherical equivalent, manifest and topographic astigmatism, uncorrected visual acuity, and best-corrected visual acuity did not differ significantly between the 2 groups at 6 months. Mean pre- and postoperative ECC did not differ significantly between the group that underwent repositioning/rebubbling and the group that did not (preoperative counts 2742 +/- 268 vs. 2747 +/- 353 and postoperative counts 1590 +/- 367 vs. 1746 +/- 491, respectively). Endothelial cell loss also did not differ significantly between the 2 groups, although there was a trend to greater cell loss in the reattachment group (-39.4% +/- 11.1% vs. -38.3% +/- 16.2%, respectively; P = 0.6). CONCLUSION:Successful reattachment procedure does not seem to cause significant endothelial cell loss.

journal_name

Cornea

journal_title

Cornea

authors

Mashor RS,Kaiserman I,Kumar N,Sansanayudh W,Rootman D

doi

10.1097/ICO.0b013e3181cb40f6

subject

Has Abstract

pub_date

2010-08-01 00:00:00

pages

878-82

issue

eissn

0277-3740

issn

1536-4798

journal_volume

pub_type

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The effect of successful rebubbling after descemet stripping automated endothelial keratoplasty on endothelial cell counts.