Abstract:
PURPOSE:To evaluate best-corrected visual acuity (BCVA), refractive outcome, corneal topography, optical coherence tomography, and endothelial cell density 12 months after femtosecond laser-assisted inverted mushroom keratoplasty. METHODS:We performed a prospective study of a surgical case series of 5 patients undergoing femtosecond laser-assisted inverted mushroom keratoplasty for pseudophakic bullous keratopathy or pre-Descemet X-linked ichthyosis. The femtosecond laser was used to create a top-hat configuration in the donor cornea and recipient cornea. Laser parameters were as follows: energy, 4.0 (anterior inner vertical side cut and horizontal lamellar cut) and 7.0 microJ (posterior outer vertical side cut); spiral pattern with a firing rate of 15 kHz. The size of the anterior inner diameter was 7.4 mm in the donor cornea and 7.0 mm in the recipient cornea. The posterior outer diameter was 9.0 mm in all eyes. RESULTS:At 6 and 12 months after surgery, all corneal grafts were clear and showed an excellent adaptation of the lamellar donor and recipient wound surfaces. At 12 months postoperatively, BCVA averaged 20/32 (range, 20/60-20/20), refractive cylinder averaged -3.20 +/- 2.0 D, topographical cylinder averaged 3.26 +/- 2.1 D, and the mean endothelial cell density was 1793 +/- 491 cells/mm2 (range, 954-2237 cells/mm2). The mean central corneal thickness and thickness of the posterior shelf was 517 +/- 3 and 175 +/- 8 microm, respectively. CONCLUSIONS:The femtosecond laser-assisted inverted mushroom keratoplasty shows good promise in surgical treatment of corneal diseases. The multiplanar fit between the donor and recipient cornea allows early suture removal and visual rehabilitation.
journal_name
Corneajournal_title
Corneaauthors
Cheng YY,Tahzib NG,van Rij G,van Cleynenbreugel H,Pels E,Hendrikse F,Nuijts Rdoi
10.1097/QAI.0b013e31815bad0csubject
Has Abstractpub_date
2008-07-01 00:00:00pages
679-85issue
6eissn
0277-3740issn
1536-4798pii
00003226-200807000-00012journal_volume
27pub_type
杂志文章相关文献
CORNEA文献大全abstract:PURPOSE:To evaluate the prevalence of undiagnosed and asymptomatic human immunodeficiency virus (HIV) infection in patients with ocular surface squamous neoplasia (OSSN) in a referral hospital in Karnataka, South India. METHODS:A consecutive series of patients presenting with OSSN were evaluated in an academic center ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3182479aed
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:To develop a rat model of chronic Acanthamoeba polyphaga keratitis suitable for pharmacologic assessment of therapeutic agents. METHODS:An A. polyphaga isolate (ATCC #50495) was grown in peptone-yeast extract-glucose medium. Five-weeks-old, Sprague-Dawley male rats were injected with 10(3) or 10(4) trophozoite...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000214213.37447.11
更新日期:2006-06-01 00:00:00
abstract:PURPOSE:To analyze characteristics and indications for corneal transplantation in patients undergoing penetrating, lamellar, and endothelial keratoplasty in Auckland, New Zealand (NZ). METHODS:Corneal transplantation data from the NZ National Eye Bank and hospital records of corneal transplant recipients in the Auckla...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001159
更新日期:2017-05-01 00:00:00
abstract:PURPOSE:To describe the clinical results of Pentacam-based big bubble deep anterior lamellar keratoplasty (DALK) to achieve an intended 90% depth of initial lamellar trephination. METHODS:Fifty consecutive eyes of 50 patients with keratoconus, keratoglobus, and anterior stromal scars were included. DALK was performed ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31823f8c85
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:This study was designed to determine how patients with pellucid marginal corneal degeneration (PMCD) are managed in a tertiary corneal practice. METHODS:A retrospective chart review of 45 patients with PMCD from a corneal referral practice was performed. Information collected from the medical records included ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000153555.82278.5b
更新日期:2005-07-01 00:00:00
abstract:PURPOSE:To investigate the long-term effect and safety of collagen cross-linking (CXL) on patients with bullous keratopathy (BK) in a randomized control manner. It is, to our knowledge, the first randomized control study on the effect of CXL on BK. METHODS:Subjects were randomized to receive CXL as in the standard pro...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002395
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of intraoperative mitomycin-C in excision of ocular surface neoplasia for prevention of recurrence. METHODS:Seven patients (eight eyes), three men and four women, aged 56 to 87 years (mean, 73.8 years), with lesions suspicious for corneal or conjunctival neoplasia, were operated on bet...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200201000-00004
更新日期:2002-01-01 00:00:00
abstract::Two containers ("Iowa" and "Virginia") commonly used for transporting donor corneas, and various packing methods were evaluated for constancy of temperature maintenance. The larger Iowa container was found to be superior for extended storage. Packing methods that allowed the vials (containing McCarey-Kaufman medium) t...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract:PURPOSE:To describe a novel technique for removal of Descemet membrane (DM) tags or remnants in hazy corneas during Descemet stripping automated endothelial keratoplasty. METHODS:The DM tags or remnants may be difficult to visualize in the presence of hazy corneas. To identify and remove the residual DM remnants and t...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000659
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:To investigate the in vivo, corneal, biomechanical changes after corneal collagen cross-linking (CXL) using the Ocular Response Analyzer (ORA) in patients with keratoconus and post-laser in situ keratomileusis (LASIK) ectasia. METHODS:Single-center, prospective, randomized, controlled, clinical trial. After CX...
journal_title:Cornea
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/ICO.0b013e31821eea66
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:To provide 6-month results of a 1-year clinical trial evaluating conductive keratoplasty (CK) for the treatment of presbyopic symptoms in emmetropic and hyperopic eyes. METHODS:A total of 143 patients with presbyopic symptoms were enrolled in this 1-year United States FDA clinical trial and treated to improve ...
journal_title:Cornea
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1097/01.ico.0000126321.13143.a0
更新日期:2004-10-01 00:00:00
abstract::Detachment of Descemet's membrane is an unusual cause of postoperative corneal edema. The typical detachment is small and usually limited to the area near the limbal wound. These peripheral detachments usually heal without sequelae as endothelium spreads over the area and secretes a new Descemet's membrane. We report ...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract:PURPOSE:Descemetocele is a severe complication of corneal ulceration associated with a high risk of perforation. We describe a modified air-assisted deep anterior lamellar keratoplasty (DALK) technique for the surgical management of small and large epithelialized descemetoceles. METHODS:Two representative cases are pr...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3182031c81
更新日期:2011-10-01 00:00:00
abstract:PURPOSE:We describe the first case of minimally invasive corneal neurotization with the great auricular nerve (GAN) to treat unilateral neurotrophic keratopathy. We assessed corneal sensation and reinnervation by esthesiometry and confocal microscopy over 12 months of follow-up, and we provide a detailed description of...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001549
更新日期:2018-05-01 00:00:00
abstract:PURPOSE:To report the case of a patient who initially presented with primary acquired melanosis (PAM) without atypia of the conjunctiva and later developed lentigo maligna of the eyelids and PAM with atypia of the conjunctiva. We illustrate the utility of combination topical therapy with adjunctive cryotherapy to treat...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000277
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:Little research has been done on robotic ocular microsurgery. This study aims to demonstrate the feasibility of pterygium surgery using a robotic surgical system. METHODS:Robot-assisted pterygium surgery was performed on a 73-year-old patient with nasal and temporal pterygia using the DaVinci Si HD robotic Sur...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000561
更新日期:2015-10-01 00:00:00
abstract:PURPOSE:To describe the histopathologic characteristics of a 51-year-old Castroviejo square graft that remained functional for more than 50 years and to describe the wound-healing characteristics over this period of time. METHODS:An 80-year-old woman with a history of keratoconus underwent penetrating keratoplasty wit...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181861cb2
更新日期:2009-04-01 00:00:00
abstract:PURPOSE:To describe the manual provocation test (MPT), a novel test for intermittent involutional entropion of the lower eyelid. METHODS:Retrospective review of patients with intermittent entropion who presented with ocular irritation and documented inward eyelid rotation by them or their referring physicians, but who...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000762
更新日期:2016-04-01 00:00:00
abstract:PURPOSE:We have previously reported that mouse kallikrein (KLK) 22 in the lacrimal and salivary glands is an autoantigen that can induce primary Sjogren syndrome (SS) in rats. In this study, we determine whether the production of antibodies against tissue KLK is specific for SS and whether the antibody can be used as a...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31826a1e2e
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:Corneal transplantation is the standard of care for pediatric corneal opacities, but little consensus exists on optimal surgical management. Our goal was to evaluate cross-sectional data of donor and recipient characteristics collected from eye banks providing tissue for pediatric corneal transplant cases to as...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001900
更新日期:2019-05-01 00:00:00
abstract:PURPOSE:To measure the refractive index (RI) of the human corneal stroma in vivo using an objective Abbé refractometer (VCH-1) and to determine if RI of the stroma is related to age. METHODS:The VCH-1 was calibrated against a standard subjective Abbé refractometer using 7 randomly selected turbid semiliquid media. VCH...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31821008d5
更新日期:2011-12-01 00:00:00
abstract:PURPOSE:To evaluate the histologic changes in corneal structure after femtosecond laser preparation of posterior lamellar discs, more specifically, the smoothness of the stromal bed and the accuracy of the predicted depth of the horizontal lamellar cut. MATERIALS AND METHODS:Nineteen human donor eyes unsuitable for tr...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318183a379
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:To determine the effect of routine use of prophylactic oral acyclovir after penetrating keratoplasty (PK) for herpes simplex virus (HSV) keratitis on recurrence, rejection, and graft failure rates. METHODS:Records from 70 consecutive patients who underwent PK for HSV keratitis at the W.K. Kellogg Eye Center be...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3180e79b77
更新日期:2007-09-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of supratarsal triamcinolone injection in the treatment of superior limbic keratoconjunctivitis (SLK). METHODS:Forty eyes of 20 patients were diagnosed with SLK. All eyes with long-standing severe ocular irritation unresponsive to topical steroid and artificial tears were treated with ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318030d230
更新日期:2007-05-01 00:00:00
abstract:PURPOSE:To investigate the severity of keratoconus in terms of corneal elevation differences with 2 different reference surfaces using topographic analysis. METHODS:Eighty-six eyes of 50 patients with keratoconus of various clinical stages (61 male and 25 female eyes) with mean age of 37.3 ± 11.6 years were evaluated....
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0B013E31823D1EE0
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To develop a mobile app that allows photographs to be captured and edited under the overlay of images and projection of a protractor with 360 degrees axis markings, which enables the surgeon to accurately visualize the programmed and marked alignment where the intrastromal corneal ring segments (ICRS) will be i...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002385
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To compare the therapeutic effects of topical tumor necrosis factor (TNF)-α-stimulated gene/protein-6 (TSG-6) with those of cyclosporine and prednisolone eye drops in NOD.B10.H2 mice, a model for inflammation-mediated dry eye. METHODS:The 12-week-old NOD.B10.H2 mice were topically administered recombinant TSG-...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000756
更新日期:2016-04-01 00:00:00
abstract:PURPOSE:To evaluate clinical and ultrasonographic findings associated with advanced microbial keratitis with concurrent endophthalmitis. METHODS:We performed a retrospective analytical study of patients with severe microbial keratitis who underwent ocular ultrasonography for possible endophthalmitis at our institution...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002349
更新日期:2020-09-01 00:00:00
abstract::In order to evaluate the effect of a commonly used sodium hyaluronate preparation (Healon, Pharmacia AB, Uppsala, Sweden) on the incidence of endothelial rejection, endothelial cell loss, intraocular pressure, and corneal thickness after penetrating keratoplasty, we conducted a randomized clinical trial. Patients were...
journal_title:Cornea
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1990-10-01 00:00:00
abstract:PURPOSE:To investigate the efficacy of a topical anti-tumor necrosis factor-α agent, infliximab, in a mouse model of experimental dry eye (EDE). METHODS:EDE was induced in C57BL/6 mice, with or without topical treatment consisting of balanced salt solution or 0.001%, 0.01%, or 0.1% infliximab solutions. Tear volume an...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31826a80ea
更新日期:2012-11-01 00:00:00