The intraoperative use of mitomycin-C in excision of ocular surface neoplasia with or without limbal autograft transplantation.

abstract：PURPOSE:To study alterations of the extracellular matrix (ECM) and basement membrane (BM) components in human keratoconus corneas. METHODS:Fifteen normal and 13 keratoconus corneas were characterized by immunofluorescence with antibodies to 23 ECM and BM components. RESULTS:Keratoconus staining patterns for posterior...

journal_title：Cornea

authors： Kenney MC,Nesburn AB,Burgeson RE,Butkowski RJ,Ljubimov AV

更新日期：1997-05-01 00:00:00

abstract：PURPOSE:To compare the efficacy of posterior corneal elevation, measured by 2 methods, in discriminating subclinical keratoconus from normal corneas. METHODS:In 30 consecutive patients with subclinical keratoconus, and 37 candidates for refractive surgery, posterior corneal elevation was measured using Pentacam's rota...

journal_title：Cornea

authors： de Sanctis U,Aragno V,Dalmasso P,Brusasco L,Grignolo F

更新日期：2013-07-01 00:00:00

abstract：:This study attempts to measure the quantitative contribution of major chemical fractions of the whole bovine cornea to ultraviolet (UV) absorption between 240 and 300 nm, with special attention to the biologically significant range of 290-300 nm. The cornea was divided into water-insoluble, nonprotein small water-solu...

journal_title：Cornea

authors： Mitchell J,Cenedella RJ

更新日期：1995-05-01 00:00:00

abstract：PURPOSE:Study aimed to examine buttons removed from patients originally grafted for KC (group 1) for signs of recurrence at a cellular level and compare them with buttons removed from patients originally grafted for other conditions (group 2). The study further aimed to compare buttons from group 1 exhibiting high asti...

journal_title：Cornea

authors： Brookes NH,Niederer RL,Hickey D,McGhee CN,Sherwin T

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:Pseudophakic/aphakic bullous keratopathy (PBK/ABK) human corneas accumulate an extracellular matrix glycoprotein tenascin-C (TN-C), an important modulator of cell adhesion and migration. Here, the purpose was to identify specific TN-C mRNA splice variants in normal and PBK/ABK human corneas. METHODS:Convention...

journal_title：Cornea

authors： Saghizadeh M,Khin HL,Bourdon MA,Kenney MC,Ljubimov AV

更新日期：1998-05-01 00:00:00

abstract：:Epithelialization of uveal structures is frequently difficult to diagnose clinically and may require scanning and/or transmission electron microscopy to detect histologically. Since the scanning and transmission electron microscopic findings of progressive iris epithelialization have not previously been described, we ...

journal_title：Cornea

authors： Burris TE,Nordquist RE,Rowsey JJ

更新日期：1985-01-01 00:00:00

abstract：:This trial was a randomized, double-masked, crossover study during which patients with keratoconjunctivitis sicca underwent 6 weeks of treatment with either cyclosporine 1% ophthalmic ointment or placebo followed by 6 weeks of the alternative treatment. Washout periods using only unpreserved artificial tears preceded ...

journal_title：Cornea

authors： Laibovitz RA,Solch S,Andriano K,O'Connell M,Silverman MH

更新日期：1993-07-01 00:00:00

abstract：:Two containers ("Iowa" and "Virginia") commonly used for transporting donor corneas, and various packing methods were evaluated for constancy of temperature maintenance. The larger Iowa container was found to be superior for extended storage. Packing methods that allowed the vials (containing McCarey-Kaufman medium) t...

journal_title：Cornea

authors： York KK,Ward DE,Smith RE

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:To describe a surgical technique to achieve the desired plane during deep anterior lamellar keratoplasty (DALK) in eyes with Descemet membrane (DM) tears due to previous hydrops. METHODS:This was a prospective, consecutive, interventional case series of DALK in 12 keratoconic eyes with healed hydrops. Dissecti...

journal_title：Cornea

authors： Goweida MB,Sobhy M,Seifelnasr M,Liu C

更新日期：2019-04-01 00:00:00

abstract：PURPOSE:To determine the stability of the laser in situ keratomileusis (LASIK) flap in a rabbit model when subjected to vertical acceleration at nine times the force of gravity (+9 Gz) in an aircraft cockpit ejection simulator. METHODS:Thirty-six eyes from 25 New Zealand white rabbits underwent LASIK flap creation wit...

journal_title：Cornea

authors： Goodman RL,Johnson DA,Dillon H,Edelhauser HF,Waller SG

更新日期：2003-03-01 00:00:00

abstract：PURPOSE:To study the corneal biocompatibility of bevacizumab on various cultured human corneal cells. METHODS:Cell cultures of corneal keratinocytes (CKs), corneal fibroblasts (CFs), and corneal endothelial cells (CECs) were harvested from human donor eyes and exposed to various concentrations of bevacizumab (0.25-5.0...

journal_title：Cornea

authors： Yoeruek E,Spitzer MS,Tatar O,Aisenbrey S,Bartz-Schmidt KU,Szurman P

更新日期：2007-09-01 00:00:00

abstract：PURPOSE:To determine how ocular surface epithelium adjusts to an increase in cell replication after treatment with the opioid antagonist naltrexone (NTX). METHODS:Adult male rats were given twice daily injections of 30 mg/kg NTX or vehicle for 7 days. Outcomes of NTX administration included DNA synthesis (monitored wi...

journal_title：Cornea

authors： Zagon IS,Sassani JW,McLaughlin PJ

更新日期：2006-08-01 00:00:00

abstract：PURPOSE:The aim of this study was to estimate both the direct and indirect annual cost of managing dry eye disease (DED) in the United States from a societal and a payer's perspective. METHODS:A decision analytic model was developed to estimate the annual cost for managing a cohort of patients with dry eye with differ...

journal_title：Cornea

authors： Yu J,Asche CV,Fairchild CJ

更新日期：2011-04-01 00:00:00

abstract：:This report describes computerized image enhancement and analysis from the digitized image of a wide-field specular micrograph to produce an output of frequency distribution of cell areas. The steps involved including image smoothing and averaging, followed by automated scanning to detect individual cell boundaries, a...

journal_title：Cornea

authors： Hirst LW,Sterner RE,Grant DG

更新日期：1984-01-01 00:00:00

abstract：PURPOSE:We report two patients with primary graft failure (PGF) from a mutual donor. The surgery in each case was done by a different surgeon experienced in penetrating keratoplasty (PK). The cases were managed differently in the postoperative period with good visual results in both cases. We discuss the various manage...

journal_title：Cornea

authors： Van Rensburg PD,Raber IM,Laibson PR,Eagle RC Jr

更新日期：1998-03-01 00:00:00

abstract：PURPOSE:To develop and measure the uptake of a local guideline for herpes simplex keratitis (HSK) and to standardize initial antiviral therapy in Australia. METHODS:The Registered Nurses' Association of Ontario Toolkit: "Implementation of Best Practice Guidelines" was used to develop, implement, and evaluate the guide...

journal_title：Cornea

authors： Cabrera-Aguas M,Kerdraon Y,Symes RJ,McCluskey P,Samarawickrama C,Rawlinson W,Watson SL

更新日期：2020-07-01 00:00:00

abstract：PURPOSE:To ascertain whether offsetting the Descemet membrane endothelial keratoplasty (DMEK) punch can expand the donor pool in conjunction with prepunched and preloaded services by recapturing the corneas otherwise excluded by the conventional central clear zone criteria. METHODS:In this retrospective review of corn...

journal_title：Cornea

authors： Kornberg DL,Prabhu S,Sales CS,Williams RS,Clover J,Tran KD

更新日期：2020-10-01 00:00:00

abstract：PURPOSE:To evaluate the potential of human anterior lens capsule (HALC) as a carrier matrix for cultivating and transplanting human corneal endothelial cells (HCECs). METHODS:HALCs obtained from 12 patients during cataract surgery were exposed to enzyme digestion to dissolve the lens epithelium and were plated with th...

journal_title：Cornea

authors： Yoeruek E,Saygili O,Spitzer MS,Tatar O,Bartz-Schmidt KU,Szurman P

更新日期：2009-05-01 00:00:00

abstract：PURPOSE:To evaluate tear film osmolarity in patients treated with intraocular pressure-lowering medications. METHODS:Forty patients treated for glaucoma or ocular hypertension (OHT) were consecutively recruited for the study. Each patient was asked to complete an evaluation of ocular surface disease symptoms, the Ocul...

journal_title：Cornea

authors： Labbé A,Terry O,Brasnu E,Van Went C,Baudouin C

更新日期：2012-09-01 00:00:00

abstract：PURPOSE:In a Strampelli osteo-odonto-keratoprosthesis, a patch of oral mucosa is frequently used to cover the ocular surface after implantation of an osteodental lamina into the eye. In many cases, gross modifications in the eye covering become apparent a few years later. The aim of this study was to investigate the hi...

journal_title：Cornea

authors： Pecorella I,Maurizio T,Antonio C,Giancarlo F

更新日期：2006-02-01 00:00:00

abstract：PURPOSE:To evaluate the intraocular pressure (IOP) with three different instruments, Goldmann applanation tonometer (GAT), noncontact tonometer, and Tono-Pen after photorefractive keratectomy (PRK) for myopia. METHODS:A prospective case series study to evaluate preoperative and postoperative IOP measurements of 149 ey...

journal_title：Cornea

authors： Garzozi HJ,Chung HS,Lang Y,Kagemann L,Harris A

更新日期：2001-01-01 00:00:00

abstract：PURPOSE:To describe a case of Beauveria bassiana keratitis and to discuss the management of this rare condition. METHODS:An 82-year-old woman underwent surgical repair of a graft wound dehiscence. Seven months later, shortly after the removal of sutures, the patient developed a fungal keratitis. B. bassiana was identi...

journal_title：Cornea

authors： Kisla TA,Cu-Unjieng A,Sigler L,Sugar J

更新日期：2000-05-01 00:00:00

abstract：:The objective of this study was to compare four methods of counting corneal endothelial cell density using the Topcon SP 1000 microscope and Image-NET digital graphic software. Two independent observers quantified cell density from 63 endothelial photomicrographs using the various standardized techniques. The first me...

journal_title：Cornea

authors： Vecchi M,Braccio L,Orsoni JG

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:Corneal lesions such as ulcers and erosions are major complications observed in patients with severe ocular allergic diseases. We aimed to look into the relationship between specific clinical conjunctival findings and the severity of corneal complications. METHODS:Thirty eyes of 6 patients with vernal kerato...

journal_title：Cornea

authors： Tanaka M,Dogru M,Takano Y,Miyake-Kashima M,Asano-Kato N,Fukagawa K,Tsubota K,Fujishima H

更新日期：2004-07-01 00:00:00

abstract：PURPOSE:The aim of this study is to determine the effect of variation of the exposure time of near-infrared irradiation on corneal stiffening after a bacteriochlorophyll derivative (WST11) with dextran (WST-D) application. METHODS:One hundred four paired eyes of 3-month-old New Zealand White rabbits were included in t...

journal_title：Cornea

authors： Brekelmans J,Goz A,Dickman MM,Brandis A,Sui X,Wagner HD,Nuijts RMMA,Scherz A,Marcovich AL

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:To report a case of recurrent herpes simplex virus (HSV) epithelial keratitis after intravitreal triamcinolone acetonide injection for the treatment of diabetic macular edema. METHODS:Case report. RESULTS:We describe a case of a 59-year-old woman with a history of ocular HSV disease and severe proliferative d...

journal_title：Cornea

authors： Shtein RM,Stahl RM,Saxe SJ,Mian SI

更新日期：2007-06-01 00:00:00

abstract：:We evaluated the systemic absorption of ofloxacin eyedrops in humans and their availability in the tear film. Serum, urine, and tear film concentrations of ofloxacin were measured in 30 healthy women topically treated with 0.3% ofloxacin, in both eyes, four times daily for 10 1/2 days. Serum was collected before the f...

journal_title：Cornea

authors： Borrmann L,Tang-Liu DD,Kann J,Nista J,Lin ET,Frank J

更新日期：1992-05-01 00:00:00

abstract：PURPOSE:We present the clinicopathologic correlations of two case and two other clinical cases of topical anesthetic abuse keratopathy that were originally diagnosed as Acanthamoeba keratitis because of ring keratitis presentation and characteristic history. METHODS:Four patients who were referred to us with suspected...

journal_title：Cornea

authors： Varga JH,Rubinfeld RS,Wolf TC,Stutzman RD,Peele KA,Clifford WS,Madigan W

更新日期：1997-07-01 00:00:00

abstract：PURPOSE:To investigate the clinical features and outcomes for conjunctival melanoma based on patient age. METHODS:A retrospective review of patients with conjunctival melanoma managed at a single tertiary referral center from April 18, 1974, to September 9, 2019. Clinical features and outcomes were compared by patient...

journal_title：Cornea

authors： Dalvin LA,Yaghy A,Vaidya S,Pacheco RR,Perez AL,Lally SE,Shields JA,Shields CL

更新日期：2020-07-30 00:00:00

abstract：PURPOSE:To investigate the regulation of matrix metalloproteinase (MMP)-3 and MMP-13 expression over time and in the presence of cyclosporine A (CsA) in primary cultured human pterygium fibroblasts. We also examined the effects of CsA on cultured human pterygium fibroblasts. METHODS:Primary cultured human pterygium fi...

journal_title：Cornea

authors： Kim YH,Jung JC,Jung SY,Kim YI,Lee KW,Park YJ

更新日期：2015-09-01 00:00:00