Three-dimensional optical coherence tomography of granular corneal dystrophy.

abstract：:Fourteen patients presenting with neuropsychiatric manifestations of Wilson's disease were treated with oral tetrathiomolybdate (TM) for 8 weeks followed by oral zinc (Zn) maintenance therapy. The patients were evaluated prospectively at baseline and at yearly intervals for up to 5 years by slit-lamp biomicroscopy and...

journal_title：Cornea

authors： Esmaeli B,Burnstine MA,Martonyi CL,Sugar A,Johnson V,Brewer GJ

更新日期：1996-11-01 00:00:00

abstract：PURPOSE:Xeroderma pigmentosum (XP) is an extreme hypersensitivity to sunlight causing skin freckling and pigmentary changes because of defective DNA repair mechanisms. The purpose of this article is to evaluate the spectrum of ocular and systemic features in XP at a tertiary eye care center in India over 32 years. MET...

journal_title：Cornea

authors： Nandyala S,Mohamed A,Chaurasia S,Kaliki S,Ramappa M,Vemuganti GK

更新日期：2020-11-30 00:00:00

abstract：PURPOSE:To report a case of infectious crystalline keratopathy caused by Gemella haemolysans. METHODS:Observational case report. A 65-year-old woman underwent penetrating keratoplasty for contact lens-related Acanthamoeba keratitis and developed a nonhealing epithelial defect. Despite continued prophylaxis with topica...

journal_title：Cornea

authors： Elmallah MK,Munir WM,Janda WM,Tu EY

更新日期：2006-12-01 00:00:00

abstract：PURPOSE:To test whether verteporfin with a nonthermal laser increases corneal mechanical stiffness and resistance to enzymatic degradation ex vivo. METHODS:Thirty human corneas (n = 5 per group) were treated with verteporfin alone (V), irradiated with nonthermal laser therapy (689 nm) alone (NTL), or received combined...

journal_title：Cornea

authors： Alageel SA,Arafat SN,Salvador-Culla B,Kolovou PE,Jahanseir K,Kozak A,Braithwaite GJC,Ciolino JB

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To evaluate the results of a combined approach of cicatrix lysis, intraoperative mitomycin C (MMC) application, oral mucosal transplantation (OMT), and amniotic membrane transplantation (AMT) for surgery of severe symblepharon. METHODS:This prospective study included 32 eyes with severe symblepharon in which a...

journal_title：Cornea

authors： Kheirkhah A,Ghaffari R,Kaghazkanani R,Hashemi H,Behrouz MJ,Raju VK

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:To assess the keratocyte density (KD) in the cornea of patients with keratoconus not using contact lenses. METHOD:In this pilot study, the eyes (n = 68) of 35 patients with the diagnosis of keratoconus, who did not use contact lenses and the eyes(n = 70) of 35 healthy controls were prospectively examined using...

journal_title：Cornea

authors： Timucin OB,Karadag MF,Cinal A

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:To examine the applicability of culture supernatant of human amniotic cells on basic fibroblast growth factor (bFGF)-induced corneal neovascularization. METHODS:Human amniotic epithelial and mesenchymal cells (AC) were obtained from human amniotic membranes by digesting with collagenase and maintained in serum...

journal_title：Cornea

authors： Kobayashi N,Kabuyama Y,Sasaki S,Kato K,Homma Y

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:Alkaline corneal epithelial wound closure rates in rabbit eyes were compared after topical applications of amniotic membrane suspension, autologous serum, or preservative-free artificial tears. METHODS:Thirty rabbits were divided into 3 randomization groups of 10 rabbits each. Central corneal alkali wound was ...

journal_title：Cornea

authors： Shahriari HA,Tokhmehchi F,Reza M,Hashemi NF

更新日期：2008-12-01 00:00:00

abstract：PURPOSE:The purpose of this study was to determine the correct concentration and duration of application of trypan blue dye to Descemet membrane endothelial keratoplasty (DMEK) donor corneal tissue before transplant to enhance visibility while minimizing damage to the tissue. METHODS:Corneas were precut for DMEK using...

journal_title：Cornea

authors： Majmudar PA,Johnson L

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:Little research has been done on robotic ocular microsurgery. This study aims to demonstrate the feasibility of pterygium surgery using a robotic surgical system. METHODS:Robot-assisted pterygium surgery was performed on a 73-year-old patient with nasal and temporal pterygia using the DaVinci Si HD robotic Sur...

journal_title：Cornea

authors： Bourcier T,Chammas J,Becmeur PH,Danan J,Sauer A,Gaucher D,Liverneaux P,Mutter D

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:To assess the influence of donor characteristics on the outcome of anterior lamellar keratoplasty (ALK) and to evaluate whether corneal donor tissue considered unsuitable for penetrating or posterior lamellar keratoplasty due to poor endothelial condition may be safely used for ALK. METHODS:Institutional setti...

journal_title：Cornea

authors： Borderie VM,Sandali O,Basli E,Goldschmidt P,Laroche L

更新日期：2013-08-01 00:00:00

abstract：PURPOSE:Ocular injuries after exposure to the vesicant sulfur mustard (SM) are characterized by acute corneal erosions and inflammation of the anterior segment that may be followed by delayed limbal stem cell deficiency (LSCD), expressed clinically by corneal neovascularization and epithelial defects. The present study...

journal_title：Cornea

authors： Kadar T,Dachir S,Cohen M,Gutman H,Cohen L,Brandeis R,Horwitz V,Amir A

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:The aim of this study was to compare the cellular susceptibility patterns and morphologic changes in the corneal endothelium associated with the use of fourth-generation fluoroquinolones. METHOD:Endothelial susceptibility was assessed through intracameral injection of besifloxacin, gatifloxacin, and moxifloxac...

journal_title：Cornea

authors： E Silva FB,Carrijo-Carvalho LC,Teixeira A,de Freitas D,Carvalho FR

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:To study the tolerance and biocompatibility of mineral pigments for corneal pigmentation histopathologically and immunologically in an experimental animal model. METHODS:Manual intralamellar keratopigmentation was performed in 28 New Zealand white rabbits using micronized mineral pigments. Histopathological ex...

journal_title：Cornea

authors： Amesty MA,Rodriguez AE,Hernández E,De Miguel MP,Alio JL

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:We investigated the interactions of hyaluronan with extracellular matrix proteins (fibronectin, laminin, and type IV collagen) on corneal epithelial migration by using an organ-culture system of rabbit corneas. METHODS:Rabbit corneal blocks were cultured in the absence or presence of various reagents for a tot...

journal_title：Cornea

authors： Nakamura M,Nishida T

更新日期：1999-11-01 00:00:00

abstract：PURPOSE:To develop and measure the uptake of a local guideline for herpes simplex keratitis (HSK) and to standardize initial antiviral therapy in Australia. METHODS:The Registered Nurses' Association of Ontario Toolkit: "Implementation of Best Practice Guidelines" was used to develop, implement, and evaluate the guide...

journal_title：Cornea

authors： Cabrera-Aguas M,Kerdraon Y,Symes RJ,McCluskey P,Samarawickrama C,Rawlinson W,Watson SL

更新日期：2020-07-01 00:00:00

abstract：:The objective of this study was to compare four methods of counting corneal endothelial cell density using the Topcon SP 1000 microscope and Image-NET digital graphic software. Two independent observers quantified cell density from 63 endothelial photomicrographs using the various standardized techniques. The first me...

journal_title：Cornea

authors： Vecchi M,Braccio L,Orsoni JG

更新日期：1996-05-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of autologous serum (AS) eye drops combined with punctal plugs (PPs) in patients with Sjögren syndrome (SS)-related dry eye. METHODS:A retrospective clinical study was performed in patients with dry eye caused by SS. We evaluated the Schirmer test value, tear breakup time (t...

journal_title：Cornea

authors： Liu Y,Hirayama M,Cui X,Connell S,Kawakita T,Tsubota K

更新日期：2015-10-01 00:00:00

abstract：:Two cases of intracorneal hemorrhage developing as a complication of aphakic contact lens use are reported. Patient 1 had a penetrating keratoplasty to restore vision and therefore the histologic examination could be performed on the corneal button. In patient 2 the contact lens use was discontinued with partial resol...

journal_title：Cornea

authors： al-Hussaini AK,Friedlander MH,Karcioglu ZA

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:To study the effect of topical cyclosporin A on herpetic stromal keratitis (HSK) in a mouse model. METHODS:The corneas of BALB/c mice were infected with herpes simplex type 1 virus. The mice were divided into 4 groups according to topical treatment methods: vehicle solution, 0.01% cyclosporin A, 0.1% cyclospor...

journal_title：Cornea

authors： Yoon KC,Heo H,Kang IS,Lee MC,Kim KK,Park SH,Cho KO

更新日期：2008-05-01 00:00:00

abstract：PURPOSE:To assess the long-term clinical course of dry eye in patients with chronic graft-versus-host disease (cGVHD). METHODS:A prospective case series of 49 patients with cGVHD was conducted. Complete history and ophthalmic examination were performed at baseline and at 36 months (range, 26-53). All patients received...

journal_title：Cornea

authors： Sáles CS,Johnston LJ,Ta CN

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:To describe a new method of visualizing human conjunctiva goblet cell mucin secretion by using a combination of impression cytology and laser scanning microscopy. METHODS:By assembling a Z-stack of confocal microscopy images taken from human impression cytology samples, we obtained 3-dimensional information ab...

journal_title：Cornea

authors： Peral A,Pintor J

更新日期：2008-05-01 00:00:00

abstract：PURPOSE:To compare the endothelial cell damage after lens removal using a fluid-based system to conventional ultrasound. METHODS:Twenty human cadaver eyes were randomized to undergo phacoemulsification using either a fluid-based system or conventional ultrasound. After surgery, each corneoscleral button was removed, s...

journal_title：Cornea

authors： Sandoval HP,Al Sarraf O,Vroman DT,Solomon KD

更新日期：2004-10-01 00:00:00

abstract：:Posterior polymorphous corneal dystrophy (PPD) is a rare bilateral, autosomal-dominant disease. The presence of the epitheliumlike endothelium and the thickening of Descemet's membrane by the posterior collagenous layer (PCL) has been reported in the majority of published cases. Reepithelialization of the posterior co...

journal_title：Cornea

authors： Sekundo W,Lee WR,Aitken DA,Kirkness CM

更新日期：1994-11-01 00:00:00

abstract：:We examined the effects of the immunotoxin 454A12-rRa on proliferating and confluent human corneal epithelium (HCE) in vitro. Proliferating HCE was sensitive to 454A12-rRA in a dose-dependent fashion. At immunotoxin concentrations of 1,000 ng/ml for 7 days we observed an 86% reduction in cell counts. Confluent HCE was...

journal_title：Cornea

authors： Fulcher SF,Foulks GN,Wilkerson M,Cobo LM,Jaffe GJ,Hatchell DL

更新日期：1992-09-01 00:00:00

abstract：PURPOSE:To examine the carbohydrate sulfotransferase 6 (CHST6) gene in Chinese patients with macular corneal dystrophy (MCD). METHODS:Nineteen unrelated Chinese families with MCD, including 24 patients and 3 unaffected relatives, were examined. Genomic DNA was extracted from peripheral blood leukocytes. The coding reg...

journal_title：Cornea

authors： Liu Z,Tian X,Iida N,Fujiki K,Xie P,Wang W,Ma Z,Kanai A,Murakami A

更新日期：2010-08-01 00:00:00

abstract：:Viruses such as human immunodeficiency virus, herpes simplex virus, cytomegalovirus, hepatitis B, hepatitis C, and rabies can be transmitted to the recipient by corneal transplantation. Very few cases of rabies have been reported. Here we report two cases of rabies transmitted by the same donor. Both of the recipients...

journal_title：Cornea

authors： Javadi MA,Fayaz A,Mirdehghan SA,Ainollahi B

更新日期：1996-07-01 00:00:00

abstract：PURPOSE:To determine the prevalence of hepatitis B (HBV), hepatitis C (HCV), and human immunodeficiency virus (HIV) in the serum of cornea donors who had been previously screened by social and medical history by the Eye Bank of Canada, Ontario Division. METHOD:A retrospective examination of the donor records of the Ey...

journal_title：Cornea

authors： Armstrong SA,Gangam N,Chipman ML,Rootman DS

更新日期：1997-09-01 00:00:00

abstract：PURPOSE:Corneal epithelial stem cells are deficient in cases of limbal disorders, leading to conjunctival epithelial ingrowth, vascularization, and eventually visual disturbance. We introduced the eye development-associated transcription factor pax6 to embryonic stem (ES) cells and tested whether pax6-transfected cells...

journal_title：Cornea

authors： Ueno H,Kurokawa MS,Kayama M,Homma R,Kumagai Y,Masuda C,Takada E,Tsubota K,Ueno S,Suzuki N

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the antiangiogenic activity of AU6, a novel 6-amino acid peptide derived from Kringle V of human apolipoprotein (a). METHODS:RF/6A rhesus macaque choroid endothelial cells were used for in vitro studies. MTS [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sul...

journal_title：Cornea

authors： Wang Z,Zhao H,Ma JX,Xu X

更新日期：2014-04-01 00:00:00