Corneal endothelial cell damage after lens extraction using the fluid-based system compared to ultrasound phacoemulsification in human cadaver eyes.


PURPOSE:To compare the endothelial cell damage after lens removal using a fluid-based system to conventional ultrasound. METHODS:Twenty human cadaver eyes were randomized to undergo phacoemulsification using either a fluid-based system or conventional ultrasound. After surgery, each corneoscleral button was removed, stained and damaged endothelial cells per square millimeter were assessed using light microscopy. RESULTS:Fluid-based system mean damaged endothelial cells/mm was 60.2 +/- 24.1 compared with 60.4 +/- 42.6 when using conventional ultrasound (P = 0.248). CONCLUSION:The fluid-based system is as safe for the corneal endothelium as conventional ultrasound during cataract removal in human cadaver eyes.






Sandoval HP,Al Sarraf O,Vroman DT,Solomon KD




Has Abstract


2004-10-01 00:00:00
















  • The effect of successful rebubbling after descemet stripping automated endothelial keratoplasty on endothelial cell counts.

    abstract:PURPOSE:To examine the effect of successful repositioning/rebubbling of the graft on endothelial cell counts (ECCs) in eyes after Descemet stripping automated endothelial keratoplasty. METHODS:This retrospective study reviewed the outcomes of 58 eyes that underwent Descemet stripping automated endothelial keratoplasty...


    pub_type: 杂志文章


    authors: Mashor RS,Kaiserman I,Kumar N,Sansanayudh W,Rootman D

    更新日期:2010-08-01 00:00:00

  • Evaluation of Corneas from Donors With Septicemia for Use in Corneal Transplant.

    abstract:PURPOSE:To evaluate if donor corneas obtained from deaths occurring because of septicemia can be used for corneal transplantation. STUDY DESIGN:Prospective study. METHODS:Eleven septicemic donor corneas were used in the study and 10 donor corneas from deaths because of causes other than septicemia were used as contro...


    pub_type: 杂志文章


    authors: Nagaraja H,Anandula V,Kugar T,Shivanna Y,Shetty R

    更新日期:2016-08-01 00:00:00

  • Prospective evaluation of hypromellose 2% for punctal occlusion in patients with dry eye.

    abstract:PURPOSE:The aim of this study was to evaluate the effectiveness of punctal occlusion using hypromellose 2% in patients with dry eye. METHODS:In this prospective, randomized single-blinded clinical trial, we evaluated 76 eyes of 38 patients (36 women and 2 men) with dry eye secondary to rheumatic diseases. In each pati...


    pub_type: 杂志文章,随机对照试验


    authors: Capita L,Chalita MR,dos Santos-Neto LL

    更新日期:2015-02-01 00:00:00

  • One-year results of PRK in low and moderate myopia: fewer than 0.5% of eyes lose two or more lines of vision.

    abstract:PURPOSE:To retrospectively evaluate the results of myopic photorefractive keratectomy (PRK) for different levels of intended correction, including analysis of loss of best spectacle-corrected visual acuity. METHODS:Four hundred seventy-five consecutive eyes with 1 year of follow-up that had PRK for the correction of 1...


    pub_type: 杂志文章


    authors: Kapadia MS,Wilson SE

    更新日期:2000-03-01 00:00:00

  • Severe Corneal Hydrops With Suspected Posterior Stromal Rupture Managed With Ultrathin Descemet-Stripping Automated Endothelial Keratoplasty.

    abstract:PURPOSE:To describe severe acute corneal hydrops in a patient with previously undiagnosed keratoconus, in which anterior segment optical coherence tomography (AS-OCT) revealed a protruding ridge of tissue on either side of Descemet membrane (DM) break, treated successfully with ultrathin Descemet-stripping automated en...


    pub_type: 杂志文章


    authors: Blitzer AL,Liles CA,Harocopos GJ,Reidy JJ,Farooq AV

    更新日期:2020-09-09 00:00:00

  • Preservation of Biological Activity of Plasma and Platelet-Derived Eye Drops After Their Different Time and Temperature Conditions of Storage.

    abstract:PURPOSE:To analyze whether plasma rich in growth factors (PRGF) eye drops preserve their biological characteristics and activity after storage for 3 and 6 months at -20°C, at 4°C, and at room temperature for 72 hours, compared with fresh samples (t0). METHODS:Blood from 6 healthy donors was harvested and centrifuged t...


    pub_type: 杂志文章


    authors: Anitua E,de la Fuente M,Riestra A,Merayo-Lloves J,Muruzábal F,Orive G

    更新日期:2015-09-01 00:00:00

  • Temporary suture tarsorrhaphy after penetrating keratoplasty.

    abstract::Persistent donor corneal epithelial defects following penetrating keratoplasty may lead to graft failure. We herein describe a method for providing corneal protection using a temporary suture tarsorrhaphy. This technique is simple and completely reversible, and it allows continued observation and instillation of topic...


    pub_type: 杂志文章


    authors: Koenig SB,Harris GJ

    更新日期:1991-03-01 00:00:00

  • Elevated immunoglobulin to tissue KLK11 in patients with Sjögren syndrome.

    abstract:PURPOSE:We have previously reported that mouse kallikrein (KLK) 22 in the lacrimal and salivary glands is an autoantigen that can induce primary Sjogren syndrome (SS) in rats. In this study, we determine whether the production of antibodies against tissue KLK is specific for SS and whether the antibody can be used as a...


    pub_type: 杂志文章


    authors: El Annan J,Jiang G,Wang D,Zhou J,Foulks GN,Shao H

    更新日期:2013-05-01 00:00:00

  • Sequential Intracorneal Ring Segment Implantation and Corneal Transepithelial Collagen Cross-Linking in Keratoconus.

    abstract:PURPOSE:To assess the clinical outcomes after sequential surgical implantation of intracorneal ring segments and transepithelial corneal collagen cross-linking (TE-CXL) in keratoconic eyes. METHODS:In this consecutive randomized study, 40 eyes of 29 patients with progressive mild to moderate keratoconus were included ...


    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Elsaftawy HS,Ahmed MH,Saif MY,Mousa R

    更新日期:2015-11-01 00:00:00

  • Comparison of corneal endothelial image analysis by Konan SP8000 noncontact and Bio-Optics Bambi systems.

    abstract:PURPOSE:Compare corneal endothelial image analysis by Konan SP8000 and Bio-Optics Bambi image-analysis systems. METHODS:Corneal endothelial images from 98 individuals (191 eyes), ranging in age from 4 to 87 years, with a normal slit-lamp examination and no history of ocular trauma, intraocular surgery, or intraocular ...


    pub_type: 杂志文章


    authors: Benetz BA,Diaconu E,Bowlin SJ,Oak SS,Laing RA,Lass JH

    更新日期:1999-01-01 00:00:00

  • Measurement of Corneal Biomechanical Properties in Diabetes Mellitus Using the Ocular Response Analyzer and the Corvis ST.

    abstract:PURPOSE:Hyperglycemia in diabetes mellitus (DM) might induce changes in corneal biomechanics. Therefore, biomechanical properties of the cornea were measured using the ocular response analyzer and the Corvis ST. METHODS:In the study, 35 eyes of 35 diabetic patients were included. After an ophthalmological examination,...


    pub_type: 杂志文章


    authors: Ramm L,Herber R,Spoerl E,Pillunat LE,Terai N

    更新日期:2019-05-01 00:00:00

  • Transplantation of preserved human amniotic membrane for surface reconstruction in severely damaged rabbit corneas.

    abstract::After n-heptanol removal of the total corneal epithelium and a limbal lamellar keratectomy, 23 rabbit eyes developed features of limbal stem cell deficiency including conjunctival epithelial ingrowth, vascularization and chronic inflammation. One month later, 10 control eyes received a total keratectomy, and 13 experi...


    pub_type: 杂志文章


    authors: Kim JC,Tseng SC

    更新日期:1995-09-01 00:00:00

  • Albumin in the cornea is oxidized by hydrogen peroxide.

    abstract::The action of hydrogen peroxide on soluble proteins of the rat cornea has been evaluated. Two major corneal proteins are found to be oxidized by 10 mM hydrogen peroxide. Protein sequence and antibody recognition has shown one of the proteins to be albumin. Treatment of pure rat or human albumin with hydrogen peroxide ...


    pub_type: 杂志文章


    authors: Zhu L,Crouch RK

    更新日期:1992-11-01 00:00:00

  • Tandem-scanning (confocal) microscopy of the full-thickness cornea.

    abstract::We have utilized a radically new type of optical scanning microscope to study the full-thickness morphology of the intact cornea in an excised human eye bank eye and in freshly sacrificed rabbit eyes in situ. This technology enables one to study corneal morphology layer by layer in extremely thin sections, only distur...


    pub_type: 杂志文章


    authors: Lemp MA,Dilly PN,Boyde A

    更新日期:1985-01-01 00:00:00

  • Solitary epibulbar neurofibroma in older adult patients.

    abstract:PURPOSE:To report a solitary epibulbar neurofibroma in 2 elderly patients without systemic neurofibromatosis. METHODS:Case reports and literature review. RESULTS:A 67-year-old man presented with a 2-month history of left epibulbar mass. On slit-lamp examination, an 8- × 8-mm amelanotic, translucent, gelatinous, circu...


    pub_type: 杂志文章


    authors: Tanaka TS,Elner VM,Demirci H

    更新日期:2015-04-01 00:00:00

  • Correlation between tear film osmolarity, dry eye disease, and rheumatoid arthritis.

    abstract:PURPOSE:The aim of this study was to evaluate the reliability of tear film osmolarity as a diagnostic tool for detecting dry eye disease (DED) in patients with rheumatoid arthritis (RA). The second aim was to determine whether there is a relationship between tear film osmolarity, a commonly used RA score, and diagnosti...


    pub_type: 杂志文章


    authors: Schargus M,Wolf F,Tony HP,Meyer-Ter-Vehn T,Geerling G

    更新日期:2014-12-01 00:00:00

  • Corneal Stiffness and Its Relationship With Other Corneal Biomechanical and Nonbiomechanical Parameters in Myopic Eyes of Chinese Patients.

    abstract:PURPOSE:To investigate corneal stiffness and analyze its possible influence on other corneal biomechanical and nonbiomechanical parameters in myopic eyes of Chinese patients. METHODS:A total of 387 healthy (right) myopic eyes were included in this study. Corneal visualization Scheimpflug technology was used to measure...


    pub_type: 杂志文章


    authors: Zhang Y,Wang Y,Li L,Dou R,Wu W,Wu D,Jhanji V

    更新日期:2018-07-01 00:00:00

  • New Method for Removing Thermosensitive Acrylic Punctal Plugs From Lacrimal Puncta.

    abstract:PURPOSE:This study explored a new method for removing thermosensitive acrylic punctal plugs from lacrimal puncta. METHODS:A total of 14 dry eye patients (14 eyes), who required the removal of thermosensitive acrylic punctal plugs from the lacrimal puncta because of serious complications, were recruited. Among the 14 p...


    pub_type: 杂志文章


    authors: Zhang M,Zhang X

    更新日期:2015-12-01 00:00:00

  • Unusual presentation of paraproteinemic corneal infiltrates.

    abstract::A 76-year-old man with bilateral corneal infiltrates secondary to a monoclonal gammopathy of undetermined significance (MGUS) is described. The corneal changes simulated a remote lattice dystrophy. Although the clinical presentation of corneal opacities secondary to paraproteinemic conditions is somewhat variable, thi...


    pub_type: 杂志文章


    authors: Spiegel P,Grossniklaus HE,Reinhart WJ,Thomas RH

    更新日期:1990-01-01 00:00:00

  • Efficacy of plasma rich in growth factors for the treatment of dry eye.

    abstract:PURPOSE:To evaluate the efficacy of plasma rich in growth factors (PRGF) for the treatment of moderate/severe dry eye. METHODS:PRGF treatment was administered to 16 patients who had moderate/severe dry eye diagnosed and who had not responded previously to other standard treatments. We quantified several growth factors...


    pub_type: 杂志文章


    authors: López-Plandolit S,Morales MC,Freire V,Grau AE,Durán JA

    更新日期:2011-12-01 00:00:00

  • Colorimetric indicators of microbial contamination in corneal preservation medium.

    abstract:PURPOSE:To compare acid-base and oxidation-reduction indicators and to investigate the effect of buffer and temperature on the colorimetric detection of microbial growth in corneal preservation media. METHODS:Corneal preservation media containing gentamicin, without or with HEPES buffer, were prepared with either phen...


    pub_type: 杂志文章


    authors: Chu YI,Penland RL,Wilhelmus KR

    更新日期:2000-07-01 00:00:00

  • Donor-related risk factors and preoperative recipient-related risk factors for graft failure.

    abstract:PURPOSE:The aim of this study was to evaluate the outcome of penetrating keratoplasties, at the University Eye Hospital, Ludwig-Maximilians-University, Munich, Germany, using organ-cultured donor corneas and to identify preoperative risk factors, which may influence the event of graft failure. METHODS:In this study, 3...


    pub_type: 杂志文章


    authors: Yu AL,Kaiser M,Schaumberger M,Messmer E,Kook D,Welge-Lussen U

    更新日期:2014-11-01 00:00:00

  • Superficial hypertrophic dendriform epitheliopathy post-keratoplasty.

    abstract:PURPOSE:To describe a distinct and unusual superficial dendriform keratopathy that can be seen in postkeratoplasty eyes. METHOD:Three Caucasian women in their sixth decade of life were referred to the Corneal and External Disease Service at the University of California, Davis, and underwent penetrating keratoplasty fo...


    pub_type: 杂志文章


    authors: Mannis MJ,Garcia-Ferrer FJ,Davitt S

    更新日期:1998-05-01 00:00:00

  • A new nonhuman primate model of severe dry eye.

    abstract:PURPOSE:The aim of this study was to establish a new rhesus monkey model of severe dry eye. METHODS:A total of 8 rhesus monkeys were used for the study. Four monkeys had their main lacrimal gland and nictitating membrane surgically removed (group 1). Another 4 monkeys had a similar surgery with further application of ...


    pub_type: 杂志文章


    authors: Qin Y,Tan X,Zhang Y,Jie Y,Labbe A,Pan Z

    更新日期:2014-05-01 00:00:00

  • Changes in corneal autofluorescence and corneal epithelial barrier function with aging.

    abstract::Corneal epithelial permeability studies using fluorophotometers were performed on 90 eyes of 51 normal subjects. After recording the autofluorescence of the cornea (AFC) and of the lens (AFL), we applied 20 microliters of 2% sodium fluorescein to the conjunctival sac. The corneal fluorescence 45 min later (F45), which...


    pub_type: 杂志文章


    authors: Chang SW,Hu FR

    更新日期:1993-11-01 00:00:00

  • Eyelid Tattooing Induces Meibomian Gland Loss and Tear Film Instability.

    abstract:PURPOSE:To investigate the changes of meibomian gland (MG) and tear film stability in subjects with eyelid tattoos. METHODS:Forty female subjects were recruited. Ten subjects had eyelid tattoos and 30 subjects did not (control group). Tear film break-up time (TBUT) measurement and fluorescein staining were performed t...


    pub_type: 杂志文章


    authors: Lee YB,Kim JJ,Hyon JY,Wee WR,Shin YJ

    更新日期:2015-07-01 00:00:00

  • Investigation of dry eye disease and analysis of the pathogenic factors in patients after cataract surgery.

    abstract:PURPOSE:To study dry eye and analyze pathogenic factors in patients after cataract surgery. METHODS:A total of 37 patients (50 eyes) were studied by using a 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ25) and Ocular Surface Disease Index (OSDI) 3 days before and 1 week, 1 month, and 3 months a...


    pub_type: 杂志文章


    authors: Li XM,Hu L,Hu J,Wang W

    更新日期:2007-10-01 00:00:00

  • Cytotoxicity of intracameral injection drugs to corneal endothelium as evaluated by corneal endothelial cell culture.

    abstract::The cell culture method was used to quantitatively evaluate the cytotoxicity to porcine corneal endothelial cells by drugs in the usual concentrations of intracameral injections (ICI). Time-dependent cytotoxicity of drugs was evaluated quantitatively; dye exclusion assay by trypan blue was used as a viability assay; a...


    pub_type: 杂志文章


    authors: Chang CH,Lin CP,Wang HZ

    更新日期:1995-01-01 00:00:00

  • Axenfeld's anomaly associated with Down's syndrome.

    abstract::We report a case of a patient with Down's syndrome and keratoconus with acute hydrops who was incidentally noted to have Axenfeld's anomaly. We also review the systemic abnormalities associated with Axenfeld's anomaly and the implications of the diagnosis. To our knowledge, Axenfeld's anomaly has not previously been r...


    pub_type: 杂志文章


    authors: Stokes DW,Parrish CM

    更新日期:1992-03-01 00:00:00

  • Bacterial infection of a neurotrophic cornea in an immunocompromised subject.

    abstract::The following is a case report of a 61-year-old woman with a 10-year history of pemphigus vulgaris, successfully treated with steroids and cytotoxic agents. The patient developed severe herpes zoster ophthalmicus, complicated by a staph-indolent corneal ulcer. This case illustrates several of the many unfortunate opht...


    pub_type: 杂志文章


    authors: Webb RM,Duke MA

    更新日期:1985-01-01 00:00:00