MT1-MMP cleavage of the antiangiogenic proteoglycan decorin: role in corneal angiogenesis.

abstract：PURPOSE:To demonstrate the role of intrinsic hyaluronic acid (HA) in the entrapment of inflammatory cells by amniotic membrane (AM) in vitro. METHODS:HA concentration in AM was analyzed by the sandwich protein binding assay, and the approximate molecular weight was measured by gel filtration chromatography. To localiz...

journal_title：Cornea

authors： Higa K,Shimmura S,Shimazaki J,Tsubota K

更新日期：2005-03-01 00:00:00

abstract：PURPOSE:To report successful management of a case of persistent keratoconus-related hydrops with a Descemet membrane endothelial keratoplasty (DMEK) patch graft. METHODS:A case of corneal hydrops persisting for 7 months treated with DMEK was identified. The following information was collected: demographic data, surgic...

journal_title：Cornea

authors： Tu EY

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:Pseudophakic/aphakic bullous keratopathy (PBK/ABK) human corneas accumulate an extracellular matrix glycoprotein tenascin-C (TN-C), an important modulator of cell adhesion and migration. Here, the purpose was to identify specific TN-C mRNA splice variants in normal and PBK/ABK human corneas. METHODS:Convention...

journal_title：Cornea

authors： Saghizadeh M,Khin HL,Bourdon MA,Kenney MC,Ljubimov AV

更新日期：1998-05-01 00:00:00

abstract：PURPOSE:To ascertain whether offsetting the Descemet membrane endothelial keratoplasty (DMEK) punch can expand the donor pool in conjunction with prepunched and preloaded services by recapturing the corneas otherwise excluded by the conventional central clear zone criteria. METHODS:In this retrospective review of corn...

journal_title：Cornea

authors： Kornberg DL,Prabhu S,Sales CS,Williams RS,Clover J,Tran KD

更新日期：2020-10-01 00:00:00

abstract：PURPOSE:To report risk factors, clinical course, and outcome in patients with infectious keratitis following implantation of intracorneal ring segments (ICRS). METHODS:The records of 8 patients with culture-proven infectious keratitis after ICRS (Ferrara or Intacs) implantation were retrospectively reviewed. Age, gend...

journal_title：Cornea

authors： Hofling-Lima AL,Branco BC,Romano AC,Campos MQ,Moreira H,Miranda D,Kwitko S,de Freitas D,Casanova FH,Sartori M,Schor P,Souza LB

更新日期：2004-08-01 00:00:00

abstract：PURPOSE:To report a case of keratitis and corneal melt after conductive keratoplasty (CK) enhancement. METHOD:Case report. RESULTS:A 52-year-old woman with emmetropic presbyopia had undergone previous CK for monovision and underwent CK enhancement 4 years later. Postoperatively, she was managed with ketorolac trometh...

journal_title：Cornea

authors： Khalifa YM,Mifflin MD

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:Alkaline corneal epithelial wound closure rates in rabbit eyes were compared after topical applications of amniotic membrane suspension, autologous serum, or preservative-free artificial tears. METHODS:Thirty rabbits were divided into 3 randomization groups of 10 rabbits each. Central corneal alkali wound was ...

journal_title：Cornea

authors： Shahriari HA,Tokhmehchi F,Reza M,Hashemi NF

更新日期：2008-12-01 00:00:00

abstract：PURPOSE:The aim of this study was to describe the clinical features of infectious scleritis with distinct inciting events and to analyze the factors associated with poor visual outcome. METHODS:We retrospectively reviewed the predisposing factors, clinical findings, isolated organisms, complications, and outcomes of p...

journal_title：Cornea

authors： Ho YF,Yeh LK,Tan HY,Chen HC,Chen YF,Lin HC,Chen SY,Hui-Kang D,Hsiao CH

更新日期：2014-08-01 00:00:00

abstract：:Severe microbial keratitis developed in a 74-year-old women receiving long-term corticosteroids. Corneal smears revealed slender, fusiform gram-negative bacilli, but the lesion continued to worsen despite intensive antibiotic treatment. After several days, Capnocytophaga sputigena was identified on culture. Specific a...

journal_title：Cornea

authors： Ormerod LD,Foster CS,Paton BG,Haaf J,Baker AS

更新日期：1988-01-01 00:00:00

abstract：:The purpose of this study was to determine whether corneal epithelial defects and epitheliopathy in patients with unilateral dysfunction of the ophthalmic division of the trigeminal nerve (neurotrophic keratitis) is associated with reduced aqueous tear production. Sensation of the skin, cornea, and nasal mucosa, aqueo...

journal_title：Cornea

authors： Heigle TJ,Pflugfelder SC

更新日期：1996-03-01 00:00:00

abstract：PURPOSE:To describe the clinical results of Pentacam-based big bubble deep anterior lamellar keratoplasty (DALK) to achieve an intended 90% depth of initial lamellar trephination. METHODS:Fifty consecutive eyes of 50 patients with keratoconus, keratoglobus, and anterior stromal scars were included. DALK was performed ...

journal_title：Cornea

authors： Riss S,Heindl LM,Bachmann BO,Kruse FE,Cursiefen C

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:We aimed to investigate the association between atherosclerotic changes in the common carotid artery (CA) and conjunctival and corneal calcification (CCC) in maintenance hemodialysis (MHD) patients. METHODS:Fifty eyes of MHD patients with the highest CCC scores were enrolled. CCCs were scored according to the ...

journal_title：Cornea

authors： Çalışkan S,Hekimoğlu A,Çelikay O,Biçer T,Canbakan B,Aylı MD,Gürdal C

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:To determine if concurrent use of 5% natamycin and 2% econazole offers greater benefits than monotherapy with 5% natamycin for the management of fungal keratitis. METHODS:Subjects presenting to the cornea service were treated with 5% natamycin and 2% econazole used concurrently. We compared the results with a ...

journal_title：Cornea

authors： Prajna NV,Nirmalan PK,Mahalakshmi R,Lalitha P,Srinivasan M

更新日期：2004-11-01 00:00:00

abstract：PURPOSE:The aim of this study is to determine the effect of variation of the exposure time of near-infrared irradiation on corneal stiffening after a bacteriochlorophyll derivative (WST11) with dextran (WST-D) application. METHODS:One hundred four paired eyes of 3-month-old New Zealand White rabbits were included in t...

journal_title：Cornea

authors： Brekelmans J,Goz A,Dickman MM,Brandis A,Sui X,Wagner HD,Nuijts RMMA,Scherz A,Marcovich AL

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:To evaluate best-corrected visual acuity (BCVA), refractive outcome, corneal topography, optical coherence tomography, and endothelial cell density 12 months after femtosecond laser-assisted inverted mushroom keratoplasty. METHODS:We performed a prospective study of a surgical case series of 5 patients undergo...

journal_title：Cornea

authors： Cheng YY,Tahzib NG,van Rij G,van Cleynenbreugel H,Pels E,Hendrikse F,Nuijts R

更新日期：2008-07-01 00:00:00

abstract：PURPOSE:The aim of this study was to investigate the corneal thickness asymmetry indices in a large pool of patients with keratoconus derived using anterior segment optical coherence tomography (AS-OCT) in comparison with established Scheimpflug imaging-derived keratoconus classification indices. METHODS:Six specific ...

journal_title：Cornea

authors： Kanellopoulos AJ,Asimellis G

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:Ocular local anesthetics currently used in routine clinical practice for corneal anesthesia are short acting and their ability to delay corneal healing makes them unsuitable for long-term use. In this study, we examined the effect of the site 1 sodium channel blocker tetrodotoxin (TTX) on the duration of cornea...

journal_title：Cornea

authors： Wang L,Shankarappa SA,Tong R,Ciolino JB,Tsui JH,Chiang HH,Kohane DS

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:To investigate the morphological changes of corneal epithelium and subbasal nerves by in vivo confocal microscopy in patients with ocular surface disease (OSD) treated with cord blood serum (CBS) eye drops. METHODS:Twenty patients with OSD (mean age 61.1 ± 12.6 years) were included in this prospective 1-arm st...

journal_title：Cornea

authors： Giannaccare G,Buzzi M,Fresina M,Velati C,Versura P

更新日期：2017-08-01 00:00:00

abstract：:The many published studies on sterile procedures used by eye banks have included none until now on ways to optimize sterile handling of corneas procured in the morgues of forensic pathologists. The present study sought to discover if fewer positive cultures would be reported at the time of surgery from corneas which h...

journal_title：Cornea

authors： Farge EJ,Fort RA

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:To report a case of possible iatrogenic Creutzfeldt-Jakob many years following penetrating keratoplasty. DESIGN:Observational case report. METHODS:We reviewed the patient's chart, available literature on Creutzfeldt-Jakob disease, and current recommendations from the Eye Bank of America Association. RESULT...

journal_title：Cornea

authors： Hammersmith KM,Cohen EJ,Rapuano CJ,Laibson PR

更新日期：2004-05-01 00:00:00

abstract：:We have utilized a radically new type of optical scanning microscope to study the full-thickness morphology of the intact cornea in an excised human eye bank eye and in freshly sacrificed rabbit eyes in situ. This technology enables one to study corneal morphology layer by layer in extremely thin sections, only distur...

journal_title：Cornea

authors： Lemp MA,Dilly PN,Boyde A

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:To develop a rat model of chronic Acanthamoeba polyphaga keratitis suitable for pharmacologic assessment of therapeutic agents. METHODS:An A. polyphaga isolate (ATCC #50495) was grown in peptone-yeast extract-glucose medium. Five-weeks-old, Sprague-Dawley male rats were injected with 10(3) or 10(4) trophozoite...

journal_title：Cornea

authors： Vasseneix C,Gargala G,François A,Hellot MF,Duclos C,Muraine M,Benichou J,Ballet JJ,Brasseur G,Favennec L

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:To describe the viscoelastic marking technique, a novel marking technique of Descemet membrane endothelial keratoplasty (DMEK) grafts that enables usage of a single donor cornea for 2 surgeries-one that uses Descemet membrane and endothelium (DMEK) and the other using the stroma and Bowman layer. METHODS:A ret...

journal_title：Cornea

authors： Or L,Krakauer Y,Sorkin N,Knyazer B,Ashkenazy Z,Gushansky K,Dubinsky-Pertzov B,Gazit I,Einan-Lifshitz A

更新日期：2020-12-16 00:00:00

abstract：PURPOSE:To report 5-year outcomes of ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) with a central graft thickness intended to be <100 μm. METHODS:This retrospective, consecutive, interventional case series included 354 eyes with endothelial decompensation due to various causes (Fuchs endot...

journal_title：Cornea

authors： Madi S,Leon P,Nahum Y,DʼAngelo S,Giannaccare G,Beltz J,Busin M

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:We report our experience in treating two cases of Scedosporium apiospermum keratitis and provide a review of basic scientific and clinical data regarding the treatment of this visually devastating disease. METHOD:We present a case report and literature review. RESULTS:A 35-year-old woman and a 73-year-old man...

journal_title：Cornea

authors： Wu Z,Ying H,Yiu S,Irvine J,Smith R

更新日期：2002-07-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate glaucoma onset and progression after implantation of Boston Keratoprostheses (B-KPro) and the role of glaucoma surgery. METHODS:Records of patients with B-KPro implantation during 2004 to 2009 were reviewed. Parameters relevant to B-KPro surgery and glaucoma status were re...

journal_title：Cornea

authors： Crnej A,Paschalis EI,Salvador-Culla B,Tauber A,Drnovsek-Olup B,Shen LQ,Dohlman CH

更新日期：2014-04-01 00:00:00

abstract：PURPOSE:We report 2 cases in which cataract extraction with a foldable acrylic toric intraocular lens (IOL) implantation was used to correct (irregular) corneal astigmatism in patients with keratoconus and cataract. METHODS:Case 1 was a 78-year-old man with cataract and keratoconus in the left eye. He underwent phacoe...

journal_title：Cornea

authors： Visser N,Gast ST,Bauer NJ,Nuijts RM

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:To analyze the variations in tear quantity and quality after corneal collagen cross-linking (CXL) in patients with keratoconus. METHODS:This is a prospective observational study of 24 eyes with keratoconus that underwent epithelium-off CXL. The variables studied were tear film osmolarity, subjective symptoms (...

journal_title：Cornea

authors： Recalde JI,Acera A,Rodríguez-Agirretxe I,Sánchez-Tena MA,San-Cristóbal J,Durán JA

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:To describe the association of water exposure with contact lens (CL)-related disease and explore the guidelines regarding water exposure to CL wearers, provided by CL manufacturing industry, global public health, and CL-related professional associations. METHODS:A review of the literature was conducted by sear...

journal_title：Cornea

authors： Arshad M,Carnt N,Tan J,Ekkeshis I,Stapleton F

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:To evaluate adhesion of Acanthamoeba trophozoites to different silicone hydrogel contact lens (SHCL) generations with and without multipurpose contact lens care solution (MPS) treatment. METHODS:Acanthamoeba lugdunensis L3a trophozoites were inoculated onto discs trimmed from SHCLs: first generation, Air Optix...

journal_title：Cornea

authors： Lee GH,Lee JE,Park MK,Yu HS

更新日期：2016-05-01 00:00:00