Efficacy of 2-Month Treatment With Cord Blood Serum Eye Drops in Ocular Surface Disease: An In Vivo Confocal Microscopy Study.

abstract：PURPOSE:To investigate the distribution and relative level of expression of the receptor tyrosine kinases, epidermal growth factor receptor (EGFR), ErbB2 and ErbB3, in human ocular surface epithelia. METHODS:Immunofluorescent staining was performed to identify expression of the EGFR, ErbB2 and ErbB3 in the corneal, li...

journal_title：Cornea

authors： Liu Z,Carvajal M,Carraway CA,Carraway K,Pflugfelder SC

更新日期：2001-01-01 00:00:00

abstract：PURPOSE:To report the potential risk of severe positive vitreous pressure during combined penetrating keratoplasty, cataract extraction, and intraocular lens implantation (triple procedure), using positive end-expiratory pressure (PEEP) during general endotracheal anesthesia. METHODS:This is a case report of a 32-year...

journal_title：Cornea

authors： Pillar A,Jeng BH,Munir WM

更新日期：2016-11-01 00:00:00

abstract：:Corneal complications of herpes zoster ophthalmicus include pseudodendritic keratitis, late mucous adherent keratopathy, varied forms of stromal keratitis, and exposure/neurotrophic keratopathy. Prophylactic therapy of acute herpes zoster ophthalmicus with oral acyclovir is of proven benefit in reducing the incidence ...

journal_title：Cornea

authors： Cobo LM

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:To review the development of artificial corneas (prostheses and tissue equivalents) for transplantation, and to provide recent updates on our tissue-engineered replacement corneas. METHODS:Modified natural polymers and synthetic polymers were screened for their potential to replace damaged portions of the huma...

journal_title：Cornea

authors： Griffith M,Hakim M,Shimmura S,Watsky MA,Li F,Carlsson D,Doillon CJ,Nakamura M,Suuronen E,Shinozaki N,Nakata K,Sheardown H

更新日期：2002-10-01 00:00:00

abstract：PURPOSE:To assess the characteristics of BioMask as a potential masking agent for use with the excimer laser. METHOD:We addressed ablation rate, smoothness, ease of use, dioptric shift, treatment of standardized irregular topography, and ability of BioMask to induce dioptric change in vivo. RESULTS:BioMask ablates at...

journal_title：Cornea

authors： Stevens SX,Bowyer BL,Sanchez-Thorin JC,Rocha G,Young DA,Rowsey JJ

更新日期：1999-03-01 00:00:00

abstract：PURPOSE:To describe an impression cytology (IC) technique using a purpose-built, sterile, EYEPRIM IC device that can be coupled with a TRIzol reagent-based RNA extraction protocol to yield sufficient RNA for gene expression analysis. METHODS:IC samples using the EYEPRIM device were collected from the bulbar conjunctiv...

journal_title：Cornea

authors： Ganesalingam K,Ismail S,Craig JP,Sherwin T

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of superficial keratectomy and conjunctival advancement hood flap (SKCAHF) for the treatment of bullous keratopathy in canine patients. METHODS:Nine dogs (12 eyes) diagnosed with progressive corneal edema underwent superficial keratectomy followed by placement of conjunctival advanceme...

journal_title：Cornea

authors： Horikawa T,Thomasy SM,Stanley AA,Calderon AS,Li J,Linton LL,Murphy CJ

更新日期：2016-10-01 00:00:00

abstract：PURPOSE:To describe the varied presentations of posterior keratoconus. METHODS:This is a 3-year institute-based retrospective study report from June 2015 to June 2018 that describes 13 eyes of 12 patients with varied presentations of posterior keratoconus, evaluating tomographic changes using Scheimpflug corneal tomog...

journal_title：Cornea

authors： Ganesan N,Narayana S,Kasturi N,Kaliaperumal S,Srinivasan R,Vallinayagam M

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:To identify potential donor, recipient, surgical, and postoperative factors that may influence survival and visual outcome of penetrating keratoplasty (PKP). METHODS:As part of a prospective longitudinal study, the electronic records of the New Zealand National Eye Bank were analyzed for the 10-year period fro...

journal_title：Cornea

authors： Patel HY,Ormonde S,Brookes NH,Moffatt SL,Sherwin T,Pendergrast DG,McGhee CN

更新日期：2011-07-01 00:00:00

abstract：PURPOSE:To report a case series of eyes with posterior polymorphous corneal dystrophy and steep nonkeratoconic corneas. METHODS:Retrospective, descriptive, nonrandomized case series. RESULTS:Thirty-five eyes of 18 patients (14 cases from 6 families and 4 isolated cases) with diffuse posterior polymorphous corneal dys...

journal_title：Cornea

authors： Raber IM,Fintelmann R,Chhabra S,Ribeiro MP,Eagle RC Jr,Orlin SE

更新日期：2011-10-01 00:00:00

abstract：:We examined the effects of the immunotoxin 454A12-rRa on proliferating and confluent human corneal epithelium (HCE) in vitro. Proliferating HCE was sensitive to 454A12-rRA in a dose-dependent fashion. At immunotoxin concentrations of 1,000 ng/ml for 7 days we observed an 86% reduction in cell counts. Confluent HCE was...

journal_title：Cornea

authors： Fulcher SF,Foulks GN,Wilkerson M,Cobo LM,Jaffe GJ,Hatchell DL

更新日期：1992-09-01 00:00:00

abstract：PURPOSE:To report the use of anterior stromal micropuncture and amniotic membrane transplantation in the management of painful bullous keratopathy in patients with poor visual potential. METHODS:Interventional case series. A retrospective review was performed to identify all patients who were treated by one of us (A.J...

journal_title：Cornea

authors： Sonmez B,Kim BT,Aldave AJ

更新日期：2007-02-01 00:00:00

abstract：PURPOSE:This study was designed to determine how patients with pellucid marginal corneal degeneration (PMCD) are managed in a tertiary corneal practice. METHODS:A retrospective chart review of 45 patients with PMCD from a corneal referral practice was performed. Information collected from the medical records included ...

journal_title：Cornea

authors： Tzelikis PF,Cohen EJ,Rapuano CJ,Hammersmith KM,Laibson PR

更新日期：2005-07-01 00:00:00

abstract：:We performed a retrospective analysis of 291 consecutive scleral rim cultures, taken at the time of corneal transplantation, from 1981 to 1986. There were 82 positive cultures (39%), and the most common pathogen was Staphylococcus epidermidis, with 24 positive cultures (30%). Ten of these (42%) were resistant to genta...

journal_title：Cornea

authors： Mathers WD,Lemp MA

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:To evaluate the effect of a single rebubbling procedure after Descemet membrane endothelial keratoplasty (DMEK) on corneal backscatter and endothelial cell loss (ECL). METHODS:Medical records of 130 consecutive DMEK cases (118 patients) were reviewed and 3 groups were formed: group 1 (n = 32), consisting of DM...

journal_title：Cornea

authors： Lazaridis A,Fydanaki O,Giallouros E,Georgalas I,Kymionis G,Sekundo W,Droutsas K

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:To report a newly developed noninvasive method to measure the radius of tear meniscus curvature (reflective meniscometry) and its application to normal eyes, dry eyes, and other ocular surface conditions. METHODS:Two types of meniscometer--photographic and video--were devised. Both use tear meniscus as a conca...

journal_title：Cornea

authors： Yokoi N,Bron AJ,Tiffany JM,Kinoshita S

更新日期：2000-05-01 00:00:00

abstract：:The present study describes biochemical and morphological differences of pseudophakic bullous keratopathy (PBK) corneas as compared with normal corneas. At the ultrastructural level, all PBK corneas studied had abnormal fibrillar material posterior to the Descemet's membrane. In addition, two of the six PBK buttons ha...

journal_title：Cornea

authors： Kenney MC,Chwa M

更新日期：1990-04-01 00:00:00

abstract：PURPOSE:To investigate the correlations between the biomechanical indices determined in Scheimpflug-based corneal biomechanical assessments and the severity of keratoconus (KC) based on corneal tomographic assessments in patients with different stages of KC. METHODS:Fifty-three patients who presented with clinical KC ...

journal_title：Cornea

authors： Koh S,Inoue R,Ambrósio R Jr,Maeda N,Miki A,Nishida K

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:To evaluate a new method of calculation of total corneal astigmatism based on Gaussian optics and the power design of a spherocylindrical lens (C) in the healthy eye and to compare it with keratometric (K) and power vector (PV) methods. METHODS:A total of 92 healthy eyes of 92 patients (age, 17-65 years) were ...

journal_title：Cornea

authors： Piñero DP,Caballero MT,Nicolás-Albujer JM,de Fez D,Camps VJ

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:To describe the efficacy of combined excimer laser photoablation and amniotic overlay membrane in the relief of symptomatic discomfort in a 17-year-old patient who had gelatinous drop-like corneal dystrophy. METHODS:The best-corrected visual acuity (BCVA) was measured with Snellen letters. Slit-lamp examinatio...

journal_title：Cornea

authors： Alex AF,Eter N,Uhlig CE

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:To introduce an improved technique of pterygium surgery and to compare postoperative results between this technique and previous techniques. METHODS:In a retrospective survey, the records of 216 consecutive eyes with primary pterygium that underwent surgery by three different techniques were reviewed. The new ...

journal_title：Cornea

authors： Akura J,Kaneda S,Matsuura K,Setogawa A,Takeda K,Honda S

更新日期：2001-10-01 00:00:00

abstract：:The fellow normal-appearing eyes of 23 patients with unilateral aphakic bullous keratopathy were examined by wide-field specular microscopy and pachymetry. All patients had: pseudophakic or aphakic bullous keratopathy in one eye; unoperated fellow eye on no medication; no other ocular disease; and no endothelial gutta...

journal_title：Cornea

authors： Roberts CW,Boruchoff SA,Kenyon KR

更新日期：1984-01-01 00:00:00

abstract：:The following is a case report of a 61-year-old woman with a 10-year history of pemphigus vulgaris, successfully treated with steroids and cytotoxic agents. The patient developed severe herpes zoster ophthalmicus, complicated by a staph-indolent corneal ulcer. This case illustrates several of the many unfortunate opht...

journal_title：Cornea

authors： Webb RM,Duke MA

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:The p63 gene has been identified as a marker of epithelial stem cells. Because pterygium may arise through an expansion of the proliferative capacity of the conjunctiva, we sought to document the expression of p63 in normal conjunctiva and pterygium specimens. METHODS:Immunostaining for p63 expression was perf...

journal_title：Cornea

authors： Sakoonwatanyoo P,Tan DT,Smith DR

更新日期：2004-01-01 00:00:00

abstract：:This study attempts to measure the quantitative contribution of major chemical fractions of the whole bovine cornea to ultraviolet (UV) absorption between 240 and 300 nm, with special attention to the biologically significant range of 290-300 nm. The cornea was divided into water-insoluble, nonprotein small water-solu...

journal_title：Cornea

authors： Mitchell J,Cenedella RJ

更新日期：1995-05-01 00:00:00

abstract：PURPOSE:To evaluate the reliability between pneumatonometry intraocular pressure (IOP) measurement in different scleral locations and corneal IOP in a penetrating keratoplasty (PK) setting. Our aim is to validate a method that can potentially be used for patients with keratoprostheses. METHODS:This is a prospective ob...

journal_title：Cornea

authors： Magalhaes OA,Aldave AJ

更新日期：2017-10-01 00:00:00

abstract：PURPOSE:To describe a new minimally invasive surgical technique for the symptomatic management of bullous keratopathy in blind eyes. METHODS:Four patients with severe corneal edema due to endothelial decompensation and no visual function in the affected eye presented for the relief of their ocular symptoms (pain and t...

journal_title：Cornea

authors： Kymionis GD,Diakonis VF,Kankariya VP,Plaka AD,Panagopoulou SI,Kontadakis GA,Grentzelos MA,Tsilimbaris MK,Pallikaris IG

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:Microbiological contamination is a common cause for elimination of organ-cultured donor corneas. The aims of the present study were to analyze contamination rates and identify risk factors for contamination. METHODS:Retrospectively, the contamination rates of 4546 organ-cultured corneas and the causative speci...

journal_title：Cornea

authors： Linke SJ,Fricke OH,Eddy MT,Bednarz J,Druchkiv V,Kaulfers PM,Wulff B,Püschel K,Richard G,Hellwinkel OJ

更新日期：2013-02-01 00:00:00

abstract：:The purpose of this study was to determine whether corneal epithelial defects and epitheliopathy in patients with unilateral dysfunction of the ophthalmic division of the trigeminal nerve (neurotrophic keratitis) is associated with reduced aqueous tear production. Sensation of the skin, cornea, and nasal mucosa, aqueo...

journal_title：Cornea

authors： Heigle TJ,Pflugfelder SC

更新日期：1996-03-01 00:00:00

abstract：:Corneal neovascularization complicates many anterior segment diseases. Corneal laser photocoagulation using yellow light (577 nm) has been shown to reduce corneal neovascularization. No histopathologic studies of the effects of this treatment on the eye have been reported, however. Target (cornea) and nontarget (iris,...

journal_title：Cornea

authors： Hemady RK,Baer JC,Foster CS

更新日期：1993-05-01 00:00:00