Abnormal extracellular matrix in corneas with pseudophakic bullous keratopathy.

abstract：PURPOSE:To present a new treatment modality for recurrent corneal melting in a patient with a Boston type I keratoprosthesis (B-KPro) including in situ corneal cross-linking (CXL) and lamellar keratoplasty (LKP) as combined treatment. METHODS:Case report. RESULTS:Our report concerns a 27-year-old man whose case histo...

journal_title：Cornea

authors： Tóth G,Bucher F,Siebelmann S,Bachmann B,Hermann M,Szentmáry N,Nagy ZZ,Cursiefen C

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:To report the diagnosis and management of a patient with a well-tolerated, long-standing retained intracorneal foreign body. METHODS:We describe the case of a 62-year-old man with a 40-year-old retained wood foreign body within the posterior stroma of the cornea. To the authors' knowledge, this is the longest ...

journal_title：Cornea

authors： Covert DJ,Henry CR,Sheth BP

更新日期：2009-06-01 00:00:00

abstract：PURPOSE:To determine the proportion of patients who were dispensed amantadine and diagnosed with corneal edema or Fuchs dystrophy within specified time frames. METHODS:Postmarketing surveillance study. The national Veterans Health Administration pharmacy and clinical databases were used to identify a cohort of veteran...

journal_title：Cornea

authors： French DD,Margo CE

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:Clinical research addressing the issue of donor globe decontamination is yet to establish convincing data for the optimal choice of an antimicrobial agent. METHODS:In a donor-globe decontamination study, the antimicrobial effectiveness of a fluoroquinolone antibiotic (ciprofloxacin, 0.3%) was evaluated for the...

journal_title：Cornea

authors： Gopinathan U,Reddy MK,Nadkarni MS,Dasari S,Rao GN

更新日期：1998-01-01 00:00:00

abstract：PURPOSE:To investigate the efficacy of a topical anti-tumor necrosis factor-α agent, infliximab, in a mouse model of experimental dry eye (EDE). METHODS:EDE was induced in C57BL/6 mice, with or without topical treatment consisting of balanced salt solution or 0.001%, 0.01%, or 0.1% infliximab solutions. Tear volume an...

journal_title：Cornea

authors： Li Z,Choi W,Oh HJ,Yoon KC

更新日期：2012-11-01 00:00:00

abstract：:During wound healing, corneal tissue has to restore its transparency for proper vision. Various cytokines and growth factors are believed to orchestrate cellular behavior in a healing cornea. This review summarizes the roles of 1 such factor, the proinflammatory cytokine tumor necrosis factor (TNF)-alpha, in the proce...

journal_title：Cornea

authors： Saika S

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:To verify the possibility of using a commercially available ophthalmologic white light confocal microscope for imaging optical sections of donated corneas preserved at 4 degrees C, especially for endothelial evaluation. METHODS:Sixteen corneas donated to the Warsaw Eye Bank but excluded from use in surgery for...

journal_title：Cornea

authors： Szaflik JP

更新日期：2007-04-01 00:00:00

abstract：PURPOSE:To evaluate visual, refractive, and corneal topography outcomes in eyes with keratoconus that have undergone exchange/adjustment surgery with a new intrastromal corneal ring segment (ICRS) combination after unsuccessful visual and/or refractive outcomes after primary ICRS surgery. METHODS:A retrospective nonra...

journal_title：Cornea

authors： Monteiro T,Mendes JF,Faria-Correia F,Franqueira N,Madrid-Costa D,Alfonso JF

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:To assess the morphologic differences of three types of lattice corneal dystrophies (LCDs) from histologic, immunohistochemical, and ultrastructural studies. METHODS:Corneas from three patients, one LCD1, one His626Arg-LCD, and one LCD3A were processed for Congo red, betaig-h3(541-564) antibodies immunostainin...

journal_title：Cornea

authors： Schmitt-Bernard CF,Schneider C,Argilés A

更新日期：2002-07-01 00:00:00

abstract：:The action of hydrogen peroxide on soluble proteins of the rat cornea has been evaluated. Two major corneal proteins are found to be oxidized by 10 mM hydrogen peroxide. Protein sequence and antibody recognition has shown one of the proteins to be albumin. Treatment of pure rat or human albumin with hydrogen peroxide ...

journal_title：Cornea

authors： Zhu L,Crouch RK

更新日期：1992-11-01 00:00:00

abstract：PURPOSE:To describe the clinical features, histopathology, surgical management and possible etiopathogenesis of corneoscleral epithelial cysts. METHODS:Three patients with corneoscleral epithelial cysts underwent surgical ablation of the cysts. Material obtained during surgery was subjected to histopathologic analysis...

journal_title：Cornea

authors： Rao SK,Fogla R,Biswas J,Padmanabhan P

更新日期：1998-07-01 00:00:00

abstract：PURPOSE:To describe two cases of secondary congenital aphakia in association with Peters anomaly. METHODS:Two infants were noted to have corneal opacification at birth. Each child was found to have Peters anomaly requiring corneal transplantation in 1 or both eyes. RESULTS:Each child underwent penetrating keratoplast...

journal_title：Cornea

authors： Banning CS,Blackmon DM,Song CD,Grossniklaus HE

更新日期：2005-01-01 00:00:00

abstract：PURPOSE:To study the effect of topical cyclosporin A on herpetic stromal keratitis (HSK) in a mouse model. METHODS:The corneas of BALB/c mice were infected with herpes simplex type 1 virus. The mice were divided into 4 groups according to topical treatment methods: vehicle solution, 0.01% cyclosporin A, 0.1% cyclospor...

journal_title：Cornea

authors： Yoon KC,Heo H,Kang IS,Lee MC,Kim KK,Park SH,Cho KO

更新日期：2008-05-01 00:00:00

abstract：:In order to evaluate the effect of a commonly used sodium hyaluronate preparation (Healon, Pharmacia AB, Uppsala, Sweden) on the incidence of endothelial rejection, endothelial cell loss, intraocular pressure, and corneal thickness after penetrating keratoplasty, we conducted a randomized clinical trial. Patients were...

journal_title：Cornea

authors： Musch DC,Meyer RF,Sugar A,Soong HK

更新日期：1990-10-01 00:00:00

abstract：:Absorbable intracanalicular collagen implants were placed in both canaliculi of one eye of nine human volunteers. The other eye served as a control. Twenty-four hours later 2% sodium fluorescein was placed into both conjunctival sacs. Serial corneal fluorescein concentrations were measured with a scanning ocular fluor...

journal_title：Cornea

authors： Unterman SR,Reidy JJ,Hill JH,Kaufman HE

更新日期：1991-11-01 00:00:00

abstract：:Corneal epithelial permeability studies using fluorophotometers were performed on 90 eyes of 51 normal subjects. After recording the autofluorescence of the cornea (AFC) and of the lens (AFL), we applied 20 microliters of 2% sodium fluorescein to the conjunctival sac. The corneal fluorescence 45 min later (F45), which...

journal_title：Cornea

authors： Chang SW,Hu FR

更新日期：1993-11-01 00:00:00

abstract：PURPOSE:To evaluate the potential of human anterior lens capsule (HALC) as a carrier matrix for cultivating and transplanting human corneal endothelial cells (HCECs). METHODS:HALCs obtained from 12 patients during cataract surgery were exposed to enzyme digestion to dissolve the lens epithelium and were plated with th...

journal_title：Cornea

authors： Yoeruek E,Saygili O,Spitzer MS,Tatar O,Bartz-Schmidt KU,Szurman P

更新日期：2009-05-01 00:00:00

abstract：PURPOSE:To describe the effect of the corneal asphericity and toricity on the map patterns and best fit sphere (BFS) characteristics in elevation topography. METHODS:The corneal surface was modeled as a biconic surface of principal radii and asphericity values of r1 and r2 and Q1 and Q2, respectively. The apex of the ...

journal_title：Cornea

authors： Gatinel D,Malet J,Hoang-Xuan T,Azar DT

更新日期：2011-05-01 00:00:00

abstract：:A randomized, double-blind, placebo-controlled, multicenter clinical trial was conducted in five centers to assess safety, ocular tolerance, and efficacy of an ophthalmic solution of epidermal growth factor (EGF) for the treatment of traumatic corneal epithelial defects. One hundred four patients completed the study: ...

journal_title：Cornea

authors： Pastor JC,Calonge M

更新日期：1992-07-01 00:00:00

abstract：:Corneal intraepithelial neoplasia (CIN) is the term applied by some authors to the spectrum of disease ranging from mild dysplasia to carcinoma in situ. Such lesions usually are associated with dysplastic or neoplastic processes at the limbus or adjacent conjunctiva; isolated corneal dysplasia is rare. Clinically, CIN...

journal_title：Cornea

authors： Brown HH,Glasgow BJ,Holland GN,Foos RY

更新日期：1989-09-01 00:00:00

abstract：PURPOSE:To test whether verteporfin with a nonthermal laser increases corneal mechanical stiffness and resistance to enzymatic degradation ex vivo. METHODS:Thirty human corneas (n = 5 per group) were treated with verteporfin alone (V), irradiated with nonthermal laser therapy (689 nm) alone (NTL), or received combined...

journal_title：Cornea

authors： Alageel SA,Arafat SN,Salvador-Culla B,Kolovou PE,Jahanseir K,Kozak A,Braithwaite GJC,Ciolino JB

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To determine the safety and efficacy of amniotic membrane transplantation to restore and maintain a stable corneal epithelium and reduce ocular surface pain after surgical removal of band keratopathy arising from ocular causes. METHODS:Fifteen patients (16 eyes) from two centers with band keratopathy secondary...

journal_title：Cornea

authors： Anderson DF,Prabhasawat P,Alfonso E,Tseng SC

更新日期：2001-05-01 00:00:00

abstract：PURPOSE:To report the outcome and the reversibility of refractive outcomes after intrastromal corneal ring segment (ICRS) explantation in patients with keratoconus treated with ICRS implantation and same-day collagen crosslinking (CXL). METHODS:This is a retrospective review of ICRS explantation in 3 eyes of 3 patient...

journal_title：Cornea

authors： Yeung SN,Lichtinger A,Ku JY,Kim P,Low SA,Rootman DS

更新日期：2013-12-01 00:00:00

abstract：:The Corneal Recipient Registry was begun in 1985 to collect information on all recipients of corneal grafts in the province of Ontario, Canada, and on the donors providing tissue. While most of the tissue is handled by the Eye Bank of Canada (Ontario Division), ophthalmologists in centers away from the Eye Bank often ...

journal_title：Cornea

authors： Chipman ML,Willett P,Basu PK,Wolf A

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:To investigate the times for an optimally secreting meibomian gland (OSMG) to be drained of available liquid secretion, to recover with expressible liquid secretion, and then to be redrained. METHODS:Twelve subjects with no dry eye symptoms and mean age 21.3 +/- 1.9 years were recruited. Lipid layer thickness ...

journal_title：Cornea

authors： Blackie CA,Korb DR

更新日期：2009-04-01 00:00:00

abstract：PURPOSE:The aim was to assess the clinical outcomes of corneal graft infections caused by multi-drug resistant Pseudomonas aeruginosa (MDR-PA). METHODS:This is a retrospective case series of 38 patients with corneal graft infections caused by MDR-PA managed from June to December 2011. Clinical and demographic details,...

journal_title：Cornea

authors： Jain R,Murthy SI,Motukupally SR

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To provide 6-month results of a 1-year clinical trial evaluating conductive keratoplasty (CK) for the treatment of presbyopic symptoms in emmetropic and hyperopic eyes. METHODS:A total of 143 patients with presbyopic symptoms were enrolled in this 1-year United States FDA clinical trial and treated to improve ...

journal_title：Cornea

authors： McDonald MB,Durrie D,Asbell P,Maloney R,Nichamin L

更新日期：2004-10-01 00:00:00

abstract：PURPOSE:To report a case series of eyes with posterior polymorphous corneal dystrophy and steep nonkeratoconic corneas. METHODS:Retrospective, descriptive, nonrandomized case series. RESULTS:Thirty-five eyes of 18 patients (14 cases from 6 families and 4 isolated cases) with diffuse posterior polymorphous corneal dys...

journal_title：Cornea

authors： Raber IM,Fintelmann R,Chhabra S,Ribeiro MP,Eagle RC Jr,Orlin SE

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:To compare the outcome of bifold forceps and cartridge injector suture pull-through insertion techniques for Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS:A retrospective review was conducted of the medical records of all patients treated with DSAEK at the University of Iowa Hospitals ...

journal_title：Cornea

authors： Wendel LJ,Goins KM,Sutphin JE,Wagoner MD

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:To report the indications, long-term structural and functional outcomes, and prognostic factors for the success of penetrating and lamellar corneal patch grafts. METHODS:This is a retrospective analysis of 49 patients who underwent the corneal patch graft procedure over 8 years. The baseline, preoperative, and...

journal_title：Cornea

authors： Sharma S,Rathi A,Murthy SI,Trivedi M,Patel C,Mohamed A,Chaurasia S

更新日期：2020-09-29 00:00:00