Albumin in the cornea is oxidized by hydrogen peroxide.

abstract：PURPOSE:To examine the effect of successful repositioning/rebubbling of the graft on endothelial cell counts (ECCs) in eyes after Descemet stripping automated endothelial keratoplasty. METHODS:This retrospective study reviewed the outcomes of 58 eyes that underwent Descemet stripping automated endothelial keratoplasty...

journal_title：Cornea

authors： Mashor RS,Kaiserman I,Kumar N,Sansanayudh W,Rootman D

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:To investigate if amniotic membrane incubated with antibiotics could inhibit bacterial growth in vitro. METHODS:Amniotic membrane fragments were incubated with the antibiotics (netilmicin) solution; the washed and drained fragments were either tested after treatment or further incubated in antibiotic-free medi...

journal_title：Cornea

authors： Mencucci R,Menchini U,Dei R

更新日期：2006-05-01 00:00:00

abstract：PURPOSE:To assess changes in color discernment after Descemet membrane endothelial keratoplasty (DMEK) in patients with Fuchs endothelial corneal dystrophy (FECD). METHODS:In this prospective, single-center study, the study group was composed of 26 patients with FECD, aged 46 to 85 years, who underwent DMEK as a singl...

journal_title：Cornea

authors： Price DA,Price MO,Lopez A,Price FW Jr

更新日期：2016-08-01 00:00:00

abstract：:Previous studies suggest the existence of two separate and distinct mechanisms of endothelial wound healing (i.e., cell migration and cell spreading), which may be controlled by unique, injury-dependent, wound-related factors. The purpose of our study was to evaluate potential biologic mediators regulating healing of ...

journal_title：Cornea

authors： Petroll WM,Jester JV,Barry-Lane PA,Cavanagh HD

更新日期：1996-09-01 00:00:00

abstract：:Persistent donor corneal epithelial defects following penetrating keratoplasty may lead to graft failure. We herein describe a method for providing corneal protection using a temporary suture tarsorrhaphy. This technique is simple and completely reversible, and it allows continued observation and instillation of topic...

journal_title：Cornea

authors： Koenig SB,Harris GJ

更新日期：1991-03-01 00:00:00

abstract：PURPOSE:We characterized the presence of hemangiogenesis (HA) and lymphangiogenesis (LA) in human corneal specimens exhibiting 13 underlying pathologies. METHODS:Human corneal specimens were obtained from consenting subjects (n = 2 or n = 3 for each pathology; total sample size, n = 35). The pathological specimens wer...

journal_title：Cornea

authors： Tshionyi M,Shay E,Lunde E,Lin A,Han KY,Jain S,Chang JH,Azar DT

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To investigate the correlations between the biomechanical indices determined in Scheimpflug-based corneal biomechanical assessments and the severity of keratoconus (KC) based on corneal tomographic assessments in patients with different stages of KC. METHODS:Fifty-three patients who presented with clinical KC ...

journal_title：Cornea

authors： Koh S,Inoue R,Ambrósio R Jr,Maeda N,Miki A,Nishida K

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:To investigate the influence of histocompatibility Y (H-Y) antigen matching on corneal graft survival in primary penetrating keratoplasty (PK). METHODS:Medical records of patients who underwent primary PK at Seoul National University Bundang Hospital between June 2005 and October 2015 were retrospectively anal...

journal_title：Cornea

authors： Kim MJ,Kim JH,Jeon HS,Wee WR,Hyon JY

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:To evaluate changes in the donor corneal endothelium in the intact globe and in the in vivo rabbit cornea to characterize more fully the formation of "dark events" without relief images in the endothelial mosaic. METHODS:Six ex vivo human donor corneas in the intact globe and an in vivo rabbit model were used ...

journal_title：Cornea

authors： Nartey IN,Cavanagh HD,Jester JV,Andrews P,Petroll WM

更新日期：1998-09-01 00:00:00

abstract：:Eight pseudomonal species were involved in 106 invasive infections of the eye; all were community acquired. Eighteen percent of the total and 9% of the Pseudomonas aeruginosa strains were gentamicin resistant, as defined using conventional criteria. All 10 cases of "resistant" pseudomonal (nine P. aeruginosa) keratiti...

journal_title：Cornea

authors： Ormerod LD,Heseltine PN,Alfonso E,Becker MI,Kenyon KR,Baerveldt G,Smith RE

更新日期：1989-09-01 00:00:00

abstract：PURPOSE:To compare the visual results, higher-order aberrations, and corneal biomechanical properties of femtosecond small incision lenticule extraction (SMILE) at depths of 100 and 160 μm. METHODS:A prospective comparative interventional clinical trial of a series of patients who underwent SMILE. In the right eye, a ...

journal_title：Cornea

authors： El-Massry AA,Goweida MB,Shama Ael-S,Elkhawaga MH,Abdalla MF

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:To identify whether histopathologic presence of neovascularization is predictive for allograft failure following penetrating keratoplasty for herpes simplex virus (HSV) keratitis. METHODS:Retrospective, interventional case series of 62 consecutive patients with HSV keratitis who underwent penetrating keratopla...

journal_title：Cornea

authors： Garcia DD,Shtein RM,Musch DC,Elner VM

更新日期：2009-10-01 00:00:00

abstract：PURPOSE:To study the predisposing conditions, treatments, and visual outcomes of nontraumatic corneal perforations. METHODS:A retrospective chart review was conducted of all nontraumatic corneal perforations seen between January 1992 and December 1998, with > or = 3 months of follow-up, at the Cornea Service Wills Eye...

journal_title：Cornea

authors： Lekskul M,Fracht HU,Cohen EJ,Rapuano CJ,Laibson PR

更新日期：2000-05-01 00:00:00

abstract：PURPOSE:We investigated the interactions of hyaluronan with extracellular matrix proteins (fibronectin, laminin, and type IV collagen) on corneal epithelial migration by using an organ-culture system of rabbit corneas. METHODS:Rabbit corneal blocks were cultured in the absence or presence of various reagents for a tot...

journal_title：Cornea

authors： Nakamura M,Nishida T

更新日期：1999-11-01 00:00:00

abstract：PURPOSE:To evaluate the suitability of corneas from septic donors for transplantation by analyzing the discard rate in the eye bank and the clinical outcome of Descemet membrane endothelial keratoplasty (DMEK) using organ-cultured corneal grafts from septic versus nonseptic donors. METHODS:This retrospective study inc...

journal_title：Cornea

authors： Vasiliauskaitė I,de Jong M,Quilendrino R,van der Wees J,Oellerich S,Melles GRJ

更新日期：2021-01-01 00:00:00

abstract：PURPOSE:Lamellar techniques for selective replacement of diseased corneal structures have recently been improved. Descemet membrane endothelial keratoplasty (DMEK) allows the sole replacement of the endothelium--Descemet membrane layer (EDM). However, wide-spread use of DMEK is currently limited because of problems wit...

journal_title：Cornea

authors： Kruse FE,Laaser K,Cursiefen C,Heindl LM,Schlötzer-Schrehardt U,Riss S,Bachmann BO

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:To report intraoperative and 1-year postoperative results of the pachy-bubble technique for deep anterior lamellar keratoplasty (DALK). METHODS:This prospective interventional case series included 110 eyes of 107 patients with anterior corneal pathology who underwent DALK, including 78 with keratoconus. Outcom...

journal_title：Cornea

authors： Ghanem RC,Bogoni A,Ghanem VC

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:The aim of this study was to establish a new rhesus monkey model of severe dry eye. METHODS:A total of 8 rhesus monkeys were used for the study. Four monkeys had their main lacrimal gland and nictitating membrane surgically removed (group 1). Another 4 monkeys had a similar surgery with further application of ...

journal_title：Cornea

authors： Qin Y,Tan X,Zhang Y,Jie Y,Labbe A,Pan Z

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:The p63 gene has been identified as a marker of epithelial stem cells. Because pterygium may arise through an expansion of the proliferative capacity of the conjunctiva, we sought to document the expression of p63 in normal conjunctiva and pterygium specimens. METHODS:Immunostaining for p63 expression was perf...

journal_title：Cornea

authors： Sakoonwatanyoo P,Tan DT,Smith DR

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:To report a solitary epibulbar neurofibroma in 2 elderly patients without systemic neurofibromatosis. METHODS:Case reports and literature review. RESULTS:A 67-year-old man presented with a 2-month history of left epibulbar mass. On slit-lamp examination, an 8- × 8-mm amelanotic, translucent, gelatinous, circu...

journal_title：Cornea

authors： Tanaka TS,Elner VM,Demirci H

更新日期：2015-04-01 00:00:00

abstract：PURPOSE:To report the in vivo confocal microscopy (IVCM) findings of a case who underwent femtosecond laser-assisted Bowman layer transplantation (BLT). METHODS:This is a case report. RESULTS:In a 25-year-old man with previous diagnosis of keratoconus in whom a BLT was performed using the femtosecond laser-assisted t...

journal_title：Cornea

authors： García de Oteyza G,Vazquez-Romo KA,Hernández-Quintela E,de Wit Carter G,García-Albisua AM

更新日期：2020-10-19 00:00:00

abstract：PURPOSE:To investigate the clinical features and outcomes for conjunctival melanoma based on patient age. METHODS:A retrospective review of patients with conjunctival melanoma managed at a single tertiary referral center from April 18, 1974, to September 9, 2019. Clinical features and outcomes were compared by patient...

journal_title：Cornea

authors： Dalvin LA,Yaghy A,Vaidya S,Pacheco RR,Perez AL,Lally SE,Shields JA,Shields CL

更新日期：2020-07-30 00:00:00

abstract：PURPOSE:To compare intracameral 20% sulfur hexafluoride (SF6) versus 100% air as tamponade for graft attachment in Descemet membrane endothelial keratoplasty (DMEK). METHODS:Using an electronic database search on MEDLINE and CENTRAL from inception to December 2017, we performed a literature review and meta-analysis in...

journal_title：Cornea

authors： Marques RE,Guerra PS,Sousa DC,Ferreira NP,Gonçalves AI,Quintas AM,Rodrigues W

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:Recent new reports of possible iatrogenic transmission of Creutzfeldt-Jakob disease (CJD) in Europe have prompted renewed scrutiny of current Eye Bank Association of America criteria for evaluation of potential corneal donors in this country. A prior study evaluated the risk of CJD occurring in U.S. corneal don...

journal_title：Cornea

authors： Hogan RN,Brown P,Heck E,Cavanagh HD

更新日期：1999-01-01 00:00:00

abstract：:Bacterial viability in bacterial adherence to new soft contact lenses (SCLs) was studied by exposing polymacon and lidofilcon A lenses to Pseudomonas aeruginosa: L, live, untreated bacteria; H, bacteria heated for 1 h at 100 degrees C; and P, bacteria treated with 3% hydrogen peroxide for 1 h. Cultures of groups L, H,...

journal_title：Cornea

authors： John T,Refojo MF,Hanninen L,Leong FL,Medina A,Kenyon KR

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:To confirm the ocular tropism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by evaluating the expression of viral entry factors in human ocular tissues using immunohistochemistry. METHODS:Fresh donor corneas and primary explant cultures of corneal, limbal, and conjunctival epithelial cells we...

journal_title：Cornea

authors： Roehrich H,Yuan C,Hou JH

更新日期：2020-12-01 00:00:00

abstract：:Effective chemotherapy for Acanthamoeba keratitis has been hampered because of the marked resistance of the parasites to a variety of antimicrobial agents. In view of the fact that topical Brolene (propamidine isethionate) and neosporin are currently considered to be the medical treatment of choice in Europe, we sough...

journal_title：Cornea

authors： Alizadeh H,Silvany RE,Meyer DR,Dougherty JM,McCulley JP

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:To determine the factors associated with sporadic diffuse lamellar keratitis (DLK) after microkeratome laser-assisted in situ keratomileusis (LASIK). METHODS:This large database retrospective study included consecutive cases of LASIK performed between 2007 and 2016 at Care-Vision Laser Centers, Tel-Aviv, Israe...

journal_title：Cornea

authors： Segev F,Mimouni M,Sela T,Munzer G,Kaiserman I

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:To evaluate the stromal interface quality after femtosecond laser full lamellar cuts in gamma-irradiated corneas (VisionGraft sterile cornea) and to determine the limits of the cut depth using the VisionGraft as donor corneas for laser-assisted lamellar anterior keratoplasty. METHODS:Fourteen VisionGraft corne...

journal_title：Cornea

authors： Zhang C,Liu L,Tang M,Li Y,Chamberlain W,Huang D

更新日期：2015-11-01 00:00:00

abstract：PURPOSE:To compare the efficacy of posterior corneal elevation, measured by 2 methods, in discriminating subclinical keratoconus from normal corneas. METHODS:In 30 consecutive patients with subclinical keratoconus, and 37 candidates for refractive surgery, posterior corneal elevation was measured using Pentacam's rota...

journal_title：Cornea

authors： de Sanctis U,Aragno V,Dalmasso P,Brusasco L,Grignolo F

更新日期：2013-07-01 00:00:00