Effects of basic FGF and TGF beta 1 on F-actin and ZO-1 organization during cat endothelial wound healing.

abstract：PURPOSE:To examine the immediate effect of ocular rubbing on corneal topography. METHODS:Corneal topography and analysis were performed before, immediately after, and 5 minutes after eyelid rubbing in 29 volunteers without ocular disease. RESULTS:The surface regularity index increased from a baseline of 0.24 to 0.91 ...

journal_title：Cornea

authors： Mansour AM,Haddad RS

更新日期：2002-11-01 00:00:00

abstract：PURPOSE:Ocular local anesthetics currently used in routine clinical practice for corneal anesthesia are short acting and their ability to delay corneal healing makes them unsuitable for long-term use. In this study, we examined the effect of the site 1 sodium channel blocker tetrodotoxin (TTX) on the duration of cornea...

journal_title：Cornea

authors： Wang L,Shankarappa SA,Tong R,Ciolino JB,Tsui JH,Chiang HH,Kohane DS

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:To identify risk factors for the occurrence of bleeding complications after enucleation for cornea donation, in order to develop preventive activities to reduce the occurrence of bleeding complications and especially the development of ocular hematomas. METHODS:From all Dutch cornea donors deceased in the year...

journal_title：Cornea

authors： van Wijk MJ,Nijenhuis MV,Dorrepaal CA,Bokhorst AG

更新日期：2009-10-01 00:00:00

abstract：PURPOSE:Pterygium excision with conjunctival limbal autograft (CLAG) has been used successfully for prevention of pterygium recurrence. However, long-term follow-up data in the literature are lacking regarding CLAG. METHODS:Retrospective chart review and standard statistical analysis were performed. The records of 289...

journal_title：Cornea

authors： Masters JS,Harris DJ Jr

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:To assess whether omega-3 fatty acid (FA) supplementation is more efficacious than placebo in amelioration of signs and symptoms of dry eye disease. METHODS:We performed a systematic literature search in PubMed, Scopus, Web of Science, and Cochrane Central Register of Controlled Trials databases. We included r...

journal_title：Cornea

authors： Giannaccare G,Pellegrini M,Sebastiani S,Bernabei F,Roda M,Taroni L,Versura P,Campos EC

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:To report the first use of Descemet stripping automated endothelial keratoplasty (DSAEK) for spontaneous Descemet membrane detachment in a patient with osteogenesis imperfecta (OI), keratoconus, and acute bullous keratopathy. METHODS:A case report of a 25-year-old man with OI and symptomatic unilateral bullous...

journal_title：Cornea

authors： Gorovoy MS,Gorovoy IR,Ullman S,Gorovoy JB

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:To present a case of acute idiopathic endotheliitis occurred early after corneal collagen cross-linking (CXL) for progressive keratoconus, and to discuss possible risk factors, causes, and other similar complications in the literature. METHODS:A 24-year-old woman with bilateral keratoconus underwent a corneal ...

journal_title：Cornea

authors： Gumus K

更新日期：2014-06-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the antiangiogenic activity of AU6, a novel 6-amino acid peptide derived from Kringle V of human apolipoprotein (a). METHODS:RF/6A rhesus macaque choroid endothelial cells were used for in vitro studies. MTS [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sul...

journal_title：Cornea

authors： Wang Z,Zhao H,Ma JX,Xu X

更新日期：2014-04-01 00:00:00

abstract：PURPOSE:To evaluate the potential of human anterior lens capsule (HALC) as a carrier matrix for cultivating and transplanting human corneal endothelial cells (HCECs). METHODS:HALCs obtained from 12 patients during cataract surgery were exposed to enzyme digestion to dissolve the lens epithelium and were plated with th...

journal_title：Cornea

authors： Yoeruek E,Saygili O,Spitzer MS,Tatar O,Bartz-Schmidt KU,Szurman P

更新日期：2009-05-01 00:00:00

abstract：:Effective chemotherapy for Acanthamoeba keratitis has been hampered because of the marked resistance of the parasites to a variety of antimicrobial agents. In view of the fact that topical Brolene (propamidine isethionate) and neosporin are currently considered to be the medical treatment of choice in Europe, we sough...

journal_title：Cornea

authors： Alizadeh H,Silvany RE,Meyer DR,Dougherty JM,McCulley JP

更新日期：1997-01-01 00:00:00

abstract：:Utilizing transmission electron microscopy, the authors describe results obtained from cellulose acetate impressions of the bulbar conjunctiva in acquired immunodeficiency syndrome patients with cytomegalovirus (CMV) retinitis. Particles consistent with a retrovirus were isolated, but no CMV particles were demonstrate...

journal_title：Cornea

authors： Pastor SA,Shuster AR,Miller MM,Lam KW

更新日期：1991-11-01 00:00:00

abstract：PURPOSE:This study was designed to report a case of acanthamoeba keratitis in a 5-year-old child without a history of trauma or contact lens usage. METHODS:The history, clinical presentation, diagnostic, and therapeutic approaches were reviewed. RESULTS:A 5-year-old child without any history of trauma or contact lens...

journal_title：Cornea

authors： Demirci G,Ay GM,Karabas LV,Altintas O,Tamer GS,Cağlar Y

更新日期：2006-04-01 00:00:00

abstract：PURPOSE:To study the corneal biocompatibility of bevacizumab on various cultured human corneal cells. METHODS:Cell cultures of corneal keratinocytes (CKs), corneal fibroblasts (CFs), and corneal endothelial cells (CECs) were harvested from human donor eyes and exposed to various concentrations of bevacizumab (0.25-5.0...

journal_title：Cornea

authors： Yoeruek E,Spitzer MS,Tatar O,Aisenbrey S,Bartz-Schmidt KU,Szurman P

更新日期：2007-09-01 00:00:00

abstract：PURPOSE:To evaluate the prevalence of undiagnosed and asymptomatic human immunodeficiency virus (HIV) infection in patients with ocular surface squamous neoplasia (OSSN) in a referral hospital in Karnataka, South India. METHODS:A consecutive series of patients presenting with OSSN were evaluated in an academic center ...

journal_title：Cornea

authors： Pradeep TG,Gangasagara SB,Subbaramaiah GB,Suresh MB,Gangashettappa N,Durgappa R

更新日期：2012-11-01 00:00:00

abstract：PURPOSE:The efficacy of gene therapy using nonviral vector based on polyplex micelle has been studied against corneal neovascularization in mice. METHODS:A block copolymer, poly(ethylene glycol) (PEG)-block-polycation carrying ethylenediamine units in the side chain (PEG-b-P[Asp(DET)]), was prepared. PEG-b-P[Asp(DET)]...

journal_title：Cornea

authors： Iriyama A,Usui T,Yanagi Y,Amano S,Oba M,Miyata K,Nishiyama N,Kataoka K

更新日期：2011-12-01 00:00:00

abstract：PURPOSE:To describe two cases of secondary congenital aphakia in association with Peters anomaly. METHODS:Two infants were noted to have corneal opacification at birth. Each child was found to have Peters anomaly requiring corneal transplantation in 1 or both eyes. RESULTS:Each child underwent penetrating keratoplast...

journal_title：Cornea

authors： Banning CS,Blackmon DM,Song CD,Grossniklaus HE

更新日期：2005-01-01 00:00:00

abstract：PURPOSE:This study was designed to identify factors that predict longitudinal increases in corneal curvature as measured by the First Definite Apical Clearance Lens (FDACL) and flatter keratometric reading (Flat K) in keratoconus. METHODS:The Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study is a long-...

journal_title：Cornea

authors： McMahon TT,Edrington TB,Szczotka-Flynn L,Olafsson HE,Davis LJ,Schechtman KB,CLEK Study Group.

更新日期：2006-04-01 00:00:00

abstract：PURPOSE:To study two cases of corneal scarring due to trauma (one case) and infection (one case) unrelated to a previous photorefractive keratectomy (PRK) for the correction of myopia. METHODS:The patients are part of an Institutional Review Board-approved study of the safety and efficacy of PRK. Both patients underwe...

journal_title：Cornea

authors： Campos M,Takahashi R,Tanaka H,Chamon W,Allemann N

更新日期：1998-11-01 00:00:00

abstract：PURPOSE:Surgical management of advanced pellucid marginal degeneration is challenging. To correct both corneal thinning and induced corneal astigmatism, we propose a modified intrastromal lamellar sclero-keratoplasty. METHODS:Corneal thinning was mapped using perioperative optical coherence tomography (OCT). Then thro...

journal_title：Cornea

authors： Guindolet D,Petrovic A,Doan S,Cochereau I,Gabison EE

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:To evaluate the therapeutic effect of corneal cross-linking (CXL) in 2 cases of bullous keratopathy combined with corneal ulcer. METHODS:Two patients (2 eyes) were recruited for the sake of the study. Both suffered from bullous keratopathy and presented a gradually deteriorating, vision-threatening, central co...

journal_title：Cornea

authors： Kozobolis V,Labiris G,Gkika M,Sideroudi H,Kaloghianni E,Papadopoulou D,Toufexis G

更新日期：2010-02-01 00:00:00

abstract：PURPOSE:To evaluate changes in the donor corneal endothelium in the intact globe and in the in vivo rabbit cornea to characterize more fully the formation of "dark events" without relief images in the endothelial mosaic. METHODS:Six ex vivo human donor corneas in the intact globe and an in vivo rabbit model were used ...

journal_title：Cornea

authors： Nartey IN,Cavanagh HD,Jester JV,Andrews P,Petroll WM

更新日期：1998-09-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of autologous serum (AS) eye drops combined with punctal plugs (PPs) in patients with Sjögren syndrome (SS)-related dry eye. METHODS:A retrospective clinical study was performed in patients with dry eye caused by SS. We evaluated the Schirmer test value, tear breakup time (t...

journal_title：Cornea

authors： Liu Y,Hirayama M,Cui X,Connell S,Kawakita T,Tsubota K

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:The fourth-generation fluoroquinolone, moxifloxacin, covers most gram-positive and gram-negative isolates causing endophthalmitis. It is safe and effective for systemic and topical use, but only limited data are available on prophylactic intracameral administration to prevent endophthalmitis. This study uses a ...

journal_title：Cornea

authors： Kernt M,Neubauer AS,Liegl RG,Lackerbauer CA,Eibl KH,Alge CS,Ulbig MW,A AK

更新日期：2009-06-01 00:00:00

abstract：PURPOSE:To compare the visual results, higher-order aberrations, and corneal biomechanical properties of femtosecond small incision lenticule extraction (SMILE) at depths of 100 and 160 μm. METHODS:A prospective comparative interventional clinical trial of a series of patients who underwent SMILE. In the right eye, a ...

journal_title：Cornea

authors： El-Massry AA,Goweida MB,Shama Ael-S,Elkhawaga MH,Abdalla MF

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:To investigate if amniotic membrane incubated with antibiotics could inhibit bacterial growth in vitro. METHODS:Amniotic membrane fragments were incubated with the antibiotics (netilmicin) solution; the washed and drained fragments were either tested after treatment or further incubated in antibiotic-free medi...

journal_title：Cornea

authors： Mencucci R,Menchini U,Dei R

更新日期：2006-05-01 00:00:00

abstract：PURPOSE:The shape and position of the eyelids affect corneal topography. This study evaluated preoperative and postoperative corneal topography in involutional ectropion of the lower eyelid. METHODS:Eighteen patients with unilateral involutional lower eyelid ectropion underwent ophthalmic examinations and corneal topo...

journal_title：Cornea

authors： Detorakis ET,Ioannakis K,Kozobolis VP

更新日期：2005-05-01 00:00:00

abstract：PURPOSE:Little research has been done on robotic ocular microsurgery. This study aims to demonstrate the feasibility of pterygium surgery using a robotic surgical system. METHODS:Robot-assisted pterygium surgery was performed on a 73-year-old patient with nasal and temporal pterygia using the DaVinci Si HD robotic Sur...

journal_title：Cornea

authors： Bourcier T,Chammas J,Becmeur PH,Danan J,Sauer A,Gaucher D,Liverneaux P,Mutter D

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:To investigate the regulation of matrix metalloproteinase (MMP)-3 and MMP-13 expression over time and in the presence of cyclosporine A (CsA) in primary cultured human pterygium fibroblasts. We also examined the effects of CsA on cultured human pterygium fibroblasts. METHODS:Primary cultured human pterygium fi...

journal_title：Cornea

authors： Kim YH,Jung JC,Jung SY,Kim YI,Lee KW,Park YJ

更新日期：2015-09-01 00:00:00

abstract：:The treatment of herpes simplex keratitis has ranged from simple debridement to the use of prototypic antiviral agents specific to the herpes family, such as acyclovir. The various treatment modalities for dendritic keratitis, for the most part, have been effective. However, in recent years numerous reports of antivir...

journal_title：Cornea

authors： Minkovitz JB,Pepose JS

更新日期：1995-05-01 00:00:00

abstract：PURPOSE:To investigate the efficacy and safety of subconjunctival bevacizumab injection for the treatment of impending recurrent pterygium. METHODS:A prospective, randomized, single-masked, controlled trial was conducted in 80 patients with impending recurrent pterygium. Patients were randomized into 4 groups using ra...

journal_title：Cornea

authors： Lekhanont K,Patarakittam T,Thongphiew P,Suwan-apichon O,Hanutsaha P

更新日期：2012-02-01 00:00:00