Inflammation-related scarring after photorefractive keratectomy.

abstract：PURPOSE:The objective of this study was to produce a porcine corneal acellular matrix (ACM) and assess its possibility for biomedical applications. METHODS:Porcine corneas were treated with various concentrations of sodium dodecylsulfate for different lengths of time. Optimal conditions for processing the ACM were not...

journal_title：Cornea

authors： Zhou Y,Wu Z,Ge J,Wan P,Li N,Xiang P,Gao Q,Wang Z

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:To evaluate the influence of incision size on dry eye symptoms in the small incision lenticule extraction (SMILE) procedure. METHODS:Ninety-four eyes of 47 patients with myopia and/or myopic astigmatism who had undergone the SMILE procedure were enrolled in this study. The patients were divided into 3 groups a...

journal_title：Cornea

authors： Cetinkaya S,Gulmez M,Mestan E,Ucar F,Ali N

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To report intraoperative and 1-year postoperative results of the pachy-bubble technique for deep anterior lamellar keratoplasty (DALK). METHODS:This prospective interventional case series included 110 eyes of 107 patients with anterior corneal pathology who underwent DALK, including 78 with keratoconus. Outcom...

journal_title：Cornea

authors： Ghanem RC,Bogoni A,Ghanem VC

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:To describe the technique and outcomes of limbal stem cell-sparing lamellar keratoplasty (LSCS-LKP) for the management of advanced keratoglobus (KGB). METHODS:In a sequential interventional case series from March 2010 to December 2012, 8 eyes of 6 patients with advanced KGB underwent an LSCS-LKP. Three patient...

journal_title：Cornea

authors： Karimian F,Baradaran-Rafii A,Faramarzi A,Akbari M

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To present a new treatment modality for recurrent corneal melting in a patient with a Boston type I keratoprosthesis (B-KPro) including in situ corneal cross-linking (CXL) and lamellar keratoplasty (LKP) as combined treatment. METHODS:Case report. RESULTS:Our report concerns a 27-year-old man whose case histo...

journal_title：Cornea

authors： Tóth G,Bucher F,Siebelmann S,Bachmann B,Hermann M,Szentmáry N,Nagy ZZ,Cursiefen C

更新日期：2016-06-01 00:00:00

abstract：:We examined the effects of the immunotoxin 454A12-rRa on proliferating and confluent human corneal epithelium (HCE) in vitro. Proliferating HCE was sensitive to 454A12-rRA in a dose-dependent fashion. At immunotoxin concentrations of 1,000 ng/ml for 7 days we observed an 86% reduction in cell counts. Confluent HCE was...

journal_title：Cornea

authors： Fulcher SF,Foulks GN,Wilkerson M,Cobo LM,Jaffe GJ,Hatchell DL

更新日期：1992-09-01 00:00:00

abstract：PURPOSE:To study dry eye and analyze pathogenic factors in patients after cataract surgery. METHODS:A total of 37 patients (50 eyes) were studied by using a 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ25) and Ocular Surface Disease Index (OSDI) 3 days before and 1 week, 1 month, and 3 months a...

journal_title：Cornea

authors： Li XM,Hu L,Hu J,Wang W

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:To evaluate corneal graft survival over a 5-year period and to investigate whether factors related to the donor, eye bank practices, the recipient, surgery, and postoperative course influenced the outcome. METHODS:Nine hundred ninety-eight patients were randomly selected and monitored in the subsequent 3 years...

journal_title：Cornea

authors： Fasolo A,Capuzzo C,Fornea M,Franch A,Birattari F,Carito G,Cucco F,Prosdocimo G,Sala M,Delle Noci N,Primavera V,Frigo AC,Grigoletto F,Ponzin D,CORTES Study Group.

更新日期：2011-12-01 00:00:00

abstract：:The objective of this study was to compare four methods of counting corneal endothelial cell density using the Topcon SP 1000 microscope and Image-NET digital graphic software. Two independent observers quantified cell density from 63 endothelial photomicrographs using the various standardized techniques. The first me...

journal_title：Cornea

authors： Vecchi M,Braccio L,Orsoni JG

更新日期：1996-05-01 00:00:00

abstract：PURPOSE:To present the clinical outcome of 2 cases of severe dry eye associated with Nivolumab, with 1 case progressing to corneal perforation. DESIGN:Case report. CASE 1:: A 58-year-old man with metastatic melanoma was referred for the management of severe bilateral dry eyes after undergoing his sixth cycle of Nivol...

journal_title：Cornea

authors： Nguyen AT,Elia M,Materin MA,Sznol M,Chow J

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:To evaluate the reliability between pneumatonometry intraocular pressure (IOP) measurement in different scleral locations and corneal IOP in a penetrating keratoplasty (PK) setting. Our aim is to validate a method that can potentially be used for patients with keratoprostheses. METHODS:This is a prospective ob...

journal_title：Cornea

authors： Magalhaes OA,Aldave AJ

更新日期：2017-10-01 00:00:00

abstract：PURPOSE:To compare the survival rate 1 year after Descemet membrane endothelial keratoplasty (DMEK) in pseudophakic eyes versus combined phacoemulsification and DMEK (triple-DMEK). METHODS:Retrospective, interventional, consecutive case series. From all DMEKs performed from January 1, 2017, to June 30, 2018, we select...

journal_title：Cornea

authors： Fajardo-Sanchez J,de Benito-Llopis L

更新日期：2020-12-22 00:00:00

abstract：PURPOSE:To analyze the variations in tear quantity and quality after corneal collagen cross-linking (CXL) in patients with keratoconus. METHODS:This is a prospective observational study of 24 eyes with keratoconus that underwent epithelium-off CXL. The variables studied were tear film osmolarity, subjective symptoms (...

journal_title：Cornea

authors： Recalde JI,Acera A,Rodríguez-Agirretxe I,Sánchez-Tena MA,San-Cristóbal J,Durán JA

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate glaucoma onset and progression after implantation of Boston Keratoprostheses (B-KPro) and the role of glaucoma surgery. METHODS:Records of patients with B-KPro implantation during 2004 to 2009 were reviewed. Parameters relevant to B-KPro surgery and glaucoma status were re...

journal_title：Cornea

authors： Crnej A,Paschalis EI,Salvador-Culla B,Tauber A,Drnovsek-Olup B,Shen LQ,Dohlman CH

更新日期：2014-04-01 00:00:00

abstract：:Viruses such as human immunodeficiency virus, herpes simplex virus, cytomegalovirus, hepatitis B, hepatitis C, and rabies can be transmitted to the recipient by corneal transplantation. Very few cases of rabies have been reported. Here we report two cases of rabies transmitted by the same donor. Both of the recipients...

journal_title：Cornea

authors： Javadi MA,Fayaz A,Mirdehghan SA,Ainollahi B

更新日期：1996-07-01 00:00:00

abstract：PURPOSE:To compare the therapeutic effects of topical tumor necrosis factor (TNF)-α-stimulated gene/protein-6 (TSG-6) with those of cyclosporine and prednisolone eye drops in NOD.B10.H2 mice, a model for inflammation-mediated dry eye. METHODS:The 12-week-old NOD.B10.H2 mice were topically administered recombinant TSG-...

journal_title：Cornea

authors： Kim YJ,Ryu JS,Park SY,Lee HJ,Ko JH,Kim MK,Wee WR,Oh JY

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:To describe a case of conjunctival malignant melanoma associated with pseudomelanomatous alteration of the apposing tarsal conjunctiva. METHODS:A 93-year-old woman presented with an elevated, pigmented mass on her superior bulbar conjunctiva. The tumor was associated with increased pigmentation of the apposing...

journal_title：Cornea

authors： Reddy S,Finger PT,Kurli M,Bui A,Iacob CE

更新日期：2006-10-01 00:00:00

abstract：PURPOSE:To evaluate tear osmolarity and tear film parameters in patients with vitiligo. METHODS:A total of 25 eyes of 25 patients with vitiligo with periocular involvement (group 1), 30 eyes of 30 patients with vitiligo without periocular involvement (group 2), and 20 eyes of 20 controls (group 3) were evaluated using...

journal_title：Cornea

authors： Erdur SK,Aydin R,Balevi A,Ozsutcu M,Kocabora MS

更新日期：2018-04-01 00:00:00

abstract：PURPOSE:To report a case of ocular manifestations after a primary varicella infection. METHODS:Review of the literature and a case report of a 10-year-old male patient with history of blurry vision and an enlarged pupil 2 months after a varicella infection. Examination revealed uveitis, interstitial keratitis, and int...

journal_title：Cornea

authors： Fernández de Castro LE,Sarraf OA,Hawthorne KM,Solomon KD,Vroman DT

更新日期：2006-08-01 00:00:00

abstract：PURPOSE:To review the development of artificial corneas (prostheses and tissue equivalents) for transplantation, and to provide recent updates on our tissue-engineered replacement corneas. METHODS:Modified natural polymers and synthetic polymers were screened for their potential to replace damaged portions of the huma...

journal_title：Cornea

authors： Griffith M,Hakim M,Shimmura S,Watsky MA,Li F,Carlsson D,Doillon CJ,Nakamura M,Suuronen E,Shinozaki N,Nakata K,Sheardown H

更新日期：2002-10-01 00:00:00

abstract：:Contact lens (CL) fitting carries the risk of transmitting infectious agents, including adenovirus and Pseudomonas. Therefore, a number of precautions must be observed to ensure safety in the office. Paramount among these is hand washing, both immediately after contact with a patient's eyes and again between patients....

journal_title：Cornea

authors： Cohen EJ

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:The aim of this study is to expand the limited knowledge regarding autologous contralateral penetrating keratoplasty. METHODS:We report the retrospective outcomes of patients who received autokeratoplasty and contralateral opaque corneas in the donor eye at a tertiary care ophthalmology hospital in Mexico City...

journal_title：Cornea

authors： Perez-Balbuena AL,Ancona-Lezama D,Delgado-Pelayo S,Martinez JD

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:To analyze whether plasma rich in growth factors (PRGF) eye drops preserve their biological characteristics and activity after storage for 3 and 6 months at -20°C, at 4°C, and at room temperature for 72 hours, compared with fresh samples (t0). METHODS:Blood from 6 healthy donors was harvested and centrifuged t...

journal_title：Cornea

authors： Anitua E,de la Fuente M,Riestra A,Merayo-Lloves J,Muruzábal F,Orive G

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:To report 7 cases of recurrent corneal neovascularization (NV) and lipid deposition after subconjunctival injection of bevacizumab for the treatment of corneal NV-induced lipid keratopathy. METHODS:We conducted a prospective interventional case series that included 20 eyes of chronic lipid keratopathy that rec...

journal_title：Cornea

authors： Chu HS,Chen TC,Hu FR,Chen WL

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:To develop a rat model of chronic Acanthamoeba polyphaga keratitis suitable for pharmacologic assessment of therapeutic agents. METHODS:An A. polyphaga isolate (ATCC #50495) was grown in peptone-yeast extract-glucose medium. Five-weeks-old, Sprague-Dawley male rats were injected with 10(3) or 10(4) trophozoite...

journal_title：Cornea

authors： Vasseneix C,Gargala G,François A,Hellot MF,Duclos C,Muraine M,Benichou J,Ballet JJ,Brasseur G,Favennec L

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:The purpose of this study was to evaluate outcomes of Descemet's stripping automated endothelial keratoplasty (DSAEK) using anterior stromal flawed (ASF) donor corneas that were unsuitable for use in full-thickness penetrating keratoplasty as a result of stromal scars, pterygia, or previous corneal refractive s...

journal_title：Cornea

authors： Phillips PM,Terry MA,Shamie N,Chen ES,Hoar KL,Stoeger C,Friend DJ,Saad HA

更新日期：2009-09-01 00:00:00

abstract：:Regulatory T cells (Tregs) are essential for the maintenance of immune homeostasis. Studies of Treg are not only necessary for understanding the mechanism of immune homeostasis but also extremely useful for the development of treatments of various immune diseases. Forkhead box P3 (Foxp3) was identified as the master g...

journal_title：Cornea

authors： Ito M,Iizuka-Koga M,Ando M,Yoshimura A

更新日期：2018-11-01 00:00:00

abstract：:Keratoconus is a bilateral disorder of corneal shape which may be sporadic or genetically determined. Early corneal thinning suggests that a functional loss of structural elements is a primary event in the disease. Tensile strength of the cornea is reduced and is expressed by signs of rupture and scarring in Bowman's ...

journal_title：Cornea

authors： Bron AJ

更新日期：1988-01-01 00:00:00

abstract：:Salzmann's nodular degeneration is a rare, noninflammatory, slowly progressive, degenerative condition. Bluish-white nodules raised above the surface of the cornea characterize it. It has usually developed in corneas with a history of phlyctenulosis, trachoma, vernal keratoconjunctivitis, measles, scarlet fever, and v...

journal_title：Cornea

authors： Das S,Link B,Seitz B

更新日期：2005-10-01 00:00:00

abstract：PURPOSE:To compare dry eye disease parameters between small incision lenticule extraction (SMILE) and laser subepithelial keratomileusis (LASEK). METHODS:This prospective, nonrandomized study included 39 eyes of 39 patients who underwent SMILE (n = 19) and LASEK (n = 20). Dry eye disease parameters included Ocular Sur...

journal_title：Cornea

authors： Chung B,Choi M,Lee KY,Kim EK,Seo KY,Jun I,Kim KY,Kim TI

更新日期：2020-04-01 00:00:00