Clinical Outcomes of Descemet Membrane Endothelial Keratoplasty in Pseudophakic Eyes Compared With Triple-DMEK at 1-Year Follow-up.

Abstract:

PURPOSE:To compare the survival rate 1 year after Descemet membrane endothelial keratoplasty (DMEK) in pseudophakic eyes versus combined phacoemulsification and DMEK (triple-DMEK). METHODS:Retrospective, interventional, consecutive case series. From all DMEKs performed from January 1, 2017, to June 30, 2018, we selected those performed in pseudophakic eyes (pseudophakic DMEK) and those that underwent triple-DMEK. We compared the survival rate 1 year after surgery between both groups and between the Fuchs endothelial dystrophy (FED) cases in both groups, plus the FED cases versus the pseudophakic bullous keratopathy (PBK) cases in the pseudophakic DMEK group. Second, we compared rebubbling rates and the influence of the use of gas or corneal sutures on rebubbling and dislocation rates. RESULTS:A total of 329 eyes were included (218 eyes pseudophakic DMEK and 111 eyes triple-DMEK). The survival rate at 1 year was 79.8% and 90%, respectively (P = 0.03). When only FED cases were included (133 pseudophakic DMEK and 108 triple-DMEK), no significant difference was found (87.9% vs. 90.7%, P = 0.59). Within the pseudophakic DMEK group, the survival rate was higher in FED cases (87.8%) compared with PBK cases (66.6%) (P = 0.0001). Rebubbling rates were 21.1% (pseudophakic DMEK) and 17.1% (triple-DMEK) (P = 0.39). The use of gas versus air or placing corneal sutures did not seem to influence the rebubbling (P = 0.64 and P = 0.13, respectively) or dislocation rates (P = 0.71 and P = 0.53, respectively). CONCLUSIONS:In the FED cases, performing phacoemulsification before DMEK or doing a combined procedure did not seem to affect the rebubbling or survival rate up to 1 year postoperatively. PBK was associated with a higher failure rate compared with that of FED.

journal_name

Cornea

journal_title

Cornea

authors

Fajardo-Sanchez J,de Benito-Llopis L

doi

10.1097/ICO.0000000000002636

subject

Has Abstract

pub_date

2020-12-22 00:00:00

eissn

0277-3740

issn

1536-4798

pii

00003226-900000000-95866

journal_volume

Publish Ahead of Print

pub_type

杂志文章

相关文献

CORNEA文献大全
  • Intracameral moxifloxacin: in vitro safety on human ocular cells.

    abstract:PURPOSE:The fourth-generation fluoroquinolone, moxifloxacin, covers most gram-positive and gram-negative isolates causing endophthalmitis. It is safe and effective for systemic and topical use, but only limited data are available on prophylactic intracameral administration to prevent endophthalmitis. This study uses a ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318191447b

    authors: Kernt M,Neubauer AS,Liegl RG,Lackerbauer CA,Eibl KH,Alge CS,Ulbig MW,A AK

    更新日期:2009-06-01 00:00:00

  • Adenovirus epithelial keratitis.

    abstract::The authors sought to determine whether adenovirus could infect human corneal epithelium in vivo. They reviewed the medical records of six patients with adenovirus-positive viral corneal cultures who were examined at the Bascom Palmer Eye Institute between March 21, 1986, and December 31, 1992. The six patients with a...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Chodosh J,Miller D,Stroop WG,Pflugfelder SC

    更新日期:1995-03-01 00:00:00

  • Colorimetric indicators of microbial contamination in corneal preservation medium.

    abstract:PURPOSE:To compare acid-base and oxidation-reduction indicators and to investigate the effect of buffer and temperature on the colorimetric detection of microbial growth in corneal preservation media. METHODS:Corneal preservation media containing gentamicin, without or with HEPES buffer, were prepared with either phen...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200007000-00023

    authors: Chu YI,Penland RL,Wilhelmus KR

    更新日期:2000-07-01 00:00:00

  • Effect of cross-linking on corneal thickness in patients with corneal edema.

    abstract:PURPOSE:To investigate the pachymetric changes of collagen cross-linking in corneas with edema because of endothelial dysfunction. METHODS:Interventional case series included 25 eyes of 25 consecutive patients with corneal edema for at least 4 months related to Fuchs endothelial dystrophy, corneal graft failure, and p...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181c296c2

    authors: Cordeiro Barbosa MM,Barbosa JB Jr,Hirai FE,Hofling-Lima AL

    更新日期:2010-06-01 00:00:00

  • Comparison of corneal surface higher-order aberrations after endothelial keratoplasty, femtosecond laser-assisted keratoplasty, and conventional penetrating keratoplasty.

    abstract:PURPOSE:To evaluate and compare corneal higher-order aberrations (HOAs) after Descemet stripping automated endothelial keratoplasty (DSAEK), femtosecond laser-assisted penetrating keratoplasty (FLAK), and conventional penetrating keratoplasty (PKP). METHODS:A retrospective comparison of consecutive surgical series of ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3182151df2

    authors: Chamberlain W,Omid N,Lin A,Farid M,Gaster RN,Steinert RF

    更新日期:2012-01-01 00:00:00

  • Nineteen years of penetrating keratoplasty in the Hotel-Dieu Hospital in Paris.

    abstract:PURPOSE:To identify changing trends in penetrating keratoplasties (PKs) performed at the Hotel-Dieu Hospital in Paris between January 1980 and December 1999 and to explain the reasons for the changes. METHODS:We retrospectively reviewed 3,736 of the 3,836 PKs performed between January 1, 1980, and December 31, 1999, a...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200108000-00009

    authors: Legeais JM,Parc C,d'Hermies F,Pouliquen Y,Renard G

    更新日期:2001-08-01 00:00:00

  • Candida albicans interface infection after deep anterior lamellar keratoplasty.

    abstract:PURPOSE:To report a case of interface infection by Candida albicans after deep anterior lamellar keratoplasty (DALK). METHODS:A 30-year-old man with keratoconus underwent DALK. Four weeks after surgery, the patient developed multiple infiltrates in the graft-host interface with absence of intraocular infection. Donor ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318074e475

    authors: Fontana L,Parente G,Di Pede B,Tassinari G

    更新日期:2007-08-01 00:00:00

  • Extracellular matrix components in a case of retrocorneal membrane associated with syphilitic interstitial keratitis.

    abstract:PURPOSE:A web-like retrocorneal membrane (RCM) is an uncommon complication of chronic syphilitic interstitial keratitis. Extracellular matrix components have not yet been defined in this structure, although previous histologic examinations have suggested the presence of collagen. We examined the presence and distributi...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200101000-00019

    authors: Kawaguchi R,Saika S,Wakayama M,Ooshima A,Ohnishi Y,Yabe H

    更新日期:2001-01-01 00:00:00

  • A novel approach to processing descemet stripping automated endothelial keratoplasty specimens for histopathologic analysis.

    abstract:PURPOSE:To describe a new technique for handling Descemet stripping automated endothelial keratoplasty (DSAEK) specimens intraoperatively and during processing. METHODS:The processing method begins by adding a drop of eosin to the specimen intraoperatively, followed by submersion in 10% formalin solution. The specimen...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181da57f3

    authors: Steven Houston SK,Morgan O,Olsakovsky LA,Phillips PM,Ghazi NG

    更新日期:2010-12-01 00:00:00

  • Bristle Worm-Induced Keratouveitis: A Case Report.

    abstract:PURPOSE:To report keratouveitis arising from corneal penetration by a bristle worm seta (bristle). METHODS:We report on a 64-year-old woman presenting with uniocular pain, redness, reduced vision, discharge, and pustular rash of the hands after cleaning out her marine aquarium containing bristle worms and rubbing her ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002225

    authors: Kirk J,Gunn D,Wong N,Minchin E,Darcy K

    更新日期:2020-05-01 00:00:00

  • Delayed, bilateral descemet's membrane detachments with spontaneous resolution: Implications for nonsurgical treatment.

    abstract:PURPOSE:To report a case of delayed bilateral Descemet's detachment with spontaneous resolution in one eye following successful treatment of the fellow eye. METHOD:Case report. RESULTS:A 78-year-old male who underwent uncomplicated bilateral cataract extraction with phacoemulsification developed delayed bilateral Des...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318197eef1

    authors: Couch SM,Baratz KH

    更新日期:2009-12-01 00:00:00

  • Water Exposure and the Risk of Contact Lens-Related Disease.

    abstract:PURPOSE:To describe the association of water exposure with contact lens (CL)-related disease and explore the guidelines regarding water exposure to CL wearers, provided by CL manufacturing industry, global public health, and CL-related professional associations. METHODS:A review of the literature was conducted by sear...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/ICO.0000000000001898

    authors: Arshad M,Carnt N,Tan J,Ekkeshis I,Stapleton F

    更新日期:2019-06-01 00:00:00

  • Estimating Total Corneal Astigmatism From Anterior Corneal Data.

    abstract:PURPOSE:To determine keratometric astigmatism (KA), posterior corneal astigmatism (PCA), and total corneal astigmatism (TCA) in 951 normal eyes, to establish a model for estimating TCA from anterior corneal data, and to test this method in a new group of eyes with toric intraocular lenses (TIOLs). METHODS:We used a Pe...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001224

    authors: Næser K,Savini G,Bregnhøj JF

    更新日期:2017-07-01 00:00:00

  • Xylene keratopathy: a case report and review of the literature.

    abstract:PURPOSE:To report a case of direct contact xylene-related vacuolar keratopathy. METHODS:Interventional case report and review of the literature. RESULTS:Xylene keratopathy is a distinct clinical entity characterized by significantly decreased visual acuity, increased corneal thickness, and the presence of corneal epi...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/00003226-200301000-00023

    authors: Trujillo F,Dang D,Starck T

    更新日期:2003-01-01 00:00:00

  • Novel splice variants of human tenascin-C mRNA identified in normal and bullous keratopathy corneas.

    abstract:PURPOSE:Pseudophakic/aphakic bullous keratopathy (PBK/ABK) human corneas accumulate an extracellular matrix glycoprotein tenascin-C (TN-C), an important modulator of cell adhesion and migration. Here, the purpose was to identify specific TN-C mRNA splice variants in normal and PBK/ABK human corneas. METHODS:Convention...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Saghizadeh M,Khin HL,Bourdon MA,Kenney MC,Ljubimov AV

    更新日期:1998-05-01 00:00:00

  • Permanent keratoprosthesis combined with pars plana vitrectomy and silicone oil injection for visual rehabilitation of chronic hypotony and corneal opacity.

    abstract:PURPOSE:To present outcomes of combined pars plana vitrectomy, silicone oil (SO) injection, and permanent keratoprosthesis (Kpro) procedure in prephthisical eyes. METHODS:All 3 patients were monocular with chronic severe hypotony, aphakia, and total corneal opacity in their vital eye. Preoperative visual acuity ranged...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181e289a4

    authors: Utine CA,Gehlbach PL,Zimmer-Galler I,Akpek EK

    更新日期:2010-12-01 00:00:00

  • Spontaneous detachment of Descemet's membrane. Case report and literature review.

    abstract::Detachment of Descemet's membrane is an unusual cause of postoperative corneal edema. The typical detachment is small and usually limited to the area near the limbal wound. These peripheral detachments usually heal without sequelae as endothelium spreads over the area and secretes a new Descemet's membrane. We report ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Morrison LK,Talley TW,Waltman SR

    更新日期:1989-12-01 00:00:00

  • Clinical Profile of Bilateral Microsporidial Keratoconjunctivitis in Healthy Individuals-A Case Series With Long-term Follow-up.

    abstract:PURPOSE:To describe bilateral microsporidial keratoconjunctivitis in healthy individuals with long-term follow-up. METHODS:Six cases of smear-positive bilateral microsporidial keratoconjunctivitis were diagnosed and followed up during the study period August 2017 to January 2019. Associated risk factors, clinical feat...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002297

    authors: Mohanty A,Mitra S,Das S,Priyadarshini S,Sahu SK

    更新日期:2020-07-01 00:00:00

  • Comparison of Topical Application of TSG-6, Cyclosporine, and Prednisolone for Treating Dry Eye.

    abstract:PURPOSE:To compare the therapeutic effects of topical tumor necrosis factor (TNF)-α-stimulated gene/protein-6 (TSG-6) with those of cyclosporine and prednisolone eye drops in NOD.B10.H2 mice, a model for inflammation-mediated dry eye. METHODS:The 12-week-old NOD.B10.H2 mice were topically administered recombinant TSG-...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000756

    authors: Kim YJ,Ryu JS,Park SY,Lee HJ,Ko JH,Kim MK,Wee WR,Oh JY

    更新日期:2016-04-01 00:00:00

  • Comparison of 5% Sulfur Hexafluoride Versus 100% Air Tamponade in Descemet Membrane Endothelial Keratoplasty.

    abstract:PURPOSE:To compare the rebubbling rate and clinical outcomes of Descemet membrane endothelial keratoplasty (DMEK) with 5% sulfur hexafluoride (SF6) gas versus 100% air as a tamponade for graft attachment. METHODS:Retrospective, comparative, interventional case series including 368 consecutive pseudophakic eyes with Fu...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001299

    authors: Ampazas P,Droutsas K,Giallouros E,Schroeder FM,Sekundo W

    更新日期:2017-10-01 00:00:00

  • Assessment of the Tear Meniscus Using Optical Coherence Tomography in Patients With Type 2 Diabetes Mellitus.

    abstract:PURPOSE:To analyze tear meniscus dimensions with Fourier domain-optical coherence tomography (FD-OCT) in patients with type 2 diabetes mellitus. METHODS:Patients with type 2 diabetes without diabetic retinopathy (DR) (n = 54), with nonproliferative DR (n = 45), with proliferative DR (PDR) (n = 25), and controls (n = 4...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000651

    authors: Baek J,Doh SH,Chung SK

    更新日期:2015-12-01 00:00:00

  • Efficacy of 2-Month Treatment With Cord Blood Serum Eye Drops in Ocular Surface Disease: An In Vivo Confocal Microscopy Study.

    abstract:PURPOSE:To investigate the morphological changes of corneal epithelium and subbasal nerves by in vivo confocal microscopy in patients with ocular surface disease (OSD) treated with cord blood serum (CBS) eye drops. METHODS:Twenty patients with OSD (mean age 61.1 ± 12.6 years) were included in this prospective 1-arm st...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001257

    authors: Giannaccare G,Buzzi M,Fresina M,Velati C,Versura P

    更新日期:2017-08-01 00:00:00

  • Glaucoma progression and role of glaucoma surgery in patients with Boston keratoprosthesis.

    abstract:PURPOSE:The aim of this study was to evaluate glaucoma onset and progression after implantation of Boston Keratoprostheses (B-KPro) and the role of glaucoma surgery. METHODS:Records of patients with B-KPro implantation during 2004 to 2009 were reviewed. Parameters relevant to B-KPro surgery and glaucoma status were re...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000067

    authors: Crnej A,Paschalis EI,Salvador-Culla B,Tauber A,Drnovsek-Olup B,Shen LQ,Dohlman CH

    更新日期:2014-04-01 00:00:00

  • Topical drug formulations for prolonged corneal anesthesia.

    abstract:PURPOSE:Ocular local anesthetics currently used in routine clinical practice for corneal anesthesia are short acting and their ability to delay corneal healing makes them unsuitable for long-term use. In this study, we examined the effect of the site 1 sodium channel blocker tetrodotoxin (TTX) on the duration of cornea...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31828cbfe6

    authors: Wang L,Shankarappa SA,Tong R,Ciolino JB,Tsui JH,Chiang HH,Kohane DS

    更新日期:2013-07-01 00:00:00

  • Sporadic diffuse lamellar keratitis (DLK) after LASIK.

    abstract:PURPOSE:To examine the incidence of sporadic diffuse lamellar keratitis (DLK) in a large series of LASIK eyes and to suggest the hypothesis that the etiology of sporadic DLK differs from that of epidemic DLK. METHODS:The incidence and severity of DLK was noted in 1352 consecutive eyes that had primary LASIK for myopia...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200208000-00005

    authors: Wilson SE,Ambrósio R Jr

    更新日期:2002-08-01 00:00:00

  • Experimental transplantation of corneal epithelium-like cells induced by Pax6 gene transfection of mouse embryonic stem cells.

    abstract:PURPOSE:Corneal epithelial stem cells are deficient in cases of limbal disorders, leading to conjunctival epithelial ingrowth, vascularization, and eventually visual disturbance. We introduced the eye development-associated transcription factor pax6 to embryonic stem (ES) cells and tested whether pax6-transfected cells...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31814fa814

    authors: Ueno H,Kurokawa MS,Kayama M,Homma R,Kumagai Y,Masuda C,Takada E,Tsubota K,Ueno S,Suzuki N

    更新日期:2007-12-01 00:00:00

  • Correlation between clinical in vivo confocal microscopic and ex vivo histopathologic findings of Salzmann nodular degeneration.

    abstract:PURPOSE:To report clinical, in vivo confocal microscopy and ex vivo histopathologic findings of Salzmann nodular degeneration (SND). METHODS:A 48-year-old woman with symptoms of ocular irritation and decreased visual acuity caused by SND in both eyes was treated by corneal scraping and phototherapeutic keratectomy (PT...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000214215.75496.a5

    authors: Meltendorf C,Bühren J,Bug R,Ohrloff C,Kohnen T

    更新日期:2006-07-01 00:00:00

  • Changes in corneal autofluorescence and corneal epithelial barrier function with aging.

    abstract::Corneal epithelial permeability studies using fluorophotometers were performed on 90 eyes of 51 normal subjects. After recording the autofluorescence of the cornea (AFC) and of the lens (AFL), we applied 20 microliters of 2% sodium fluorescein to the conjunctival sac. The corneal fluorescence 45 min later (F45), which...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199311000-00006

    authors: Chang SW,Hu FR

    更新日期:1993-11-01 00:00:00

  • Corneal rim cultures.

    abstract::We performed a retrospective analysis of 291 consecutive scleral rim cultures, taken at the time of corneal transplantation, from 1981 to 1986. There were 82 positive cultures (39%), and the most common pathogen was Staphylococcus epidermidis, with 24 positive cultures (30%). Ten of these (42%) were resistant to genta...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-198706030-00016

    authors: Mathers WD,Lemp MA

    更新日期:1987-01-01 00:00:00

  • High-Resolution Optical Coherence Tomography Findings of Lisch Epithelial Corneal Dystrophy.

    abstract:PURPOSE:To describe a case of Lisch epithelial corneal dystrophy (LECD) and present its unique characteristics on high-resolution optical coherence tomography (HR-OCT). METHODS:A 78-year-old man with whorled corneal epithelial opacities in the right eye was referred for the evaluation of ocular surface squamous neopla...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000722

    authors: Pole C,Sise A,Joag M,Galor A,Bermudez-Magner JA,Dubovy S,Karp CL

    更新日期:2016-03-01 00:00:00