Abstract:
PURPOSE:To describe bilateral microsporidial keratoconjunctivitis in healthy individuals with long-term follow-up. METHODS:Six cases of smear-positive bilateral microsporidial keratoconjunctivitis were diagnosed and followed up during the study period August 2017 to January 2019. Associated risk factors, clinical features, coexistence with adenovirus, clinical course, and recurrence were studied. RESULTS:The mean age was 36.6 years (range: 10-65 years). The mean duration of symptoms was 13.6 days (range: 7-60 days). Predisposing risk factors were present in 4 of 6 cases. The best-corrected visual acuity at presentation was ≥20/30 in all eyes except in one. Typical microsporidial epithelial lesions were seen in only one case. Persistent lesions, clinically resembling Thygeson superficial punctate keratitis in both eyes, were observed in 3 cases. The lesions in 5 eyes resolved with topical lubricants, and the remaining 7 eyes were treated with topical steroids and tacrolimus 0.03%. Complete resolution was seen in 5 eyes at the end of 1 month, and superficial scarring at the last follow-up was seen in 5 eyes. The best-corrected visual acuity was ≤20/30 in 3 eyes at the last follow-up. The mean duration of follow-up was 7.3 months (range: 3-12 mo). CONCLUSIONS:Bilateral microsporidial keratoconjunctivitis in healthy patients has an atypical presentation with prolonged course. Microsporidia could be implicated as potential candidates in the etiopathogenesis of Thygeson superficial punctate keratitis.
journal_name
Corneajournal_title
Corneaauthors
Mohanty A,Mitra S,Das S,Priyadarshini S,Sahu SKdoi
10.1097/ICO.0000000000002297subject
Has Abstractpub_date
2020-07-01 00:00:00pages
902-908issue
7eissn
0277-3740issn
1536-4798journal_volume
39pub_type
杂志文章相关文献
CORNEA文献大全abstract::The pharmacokinetics and toxicity of subconjunctival (S/C) amphotericin B (AmB) were evaluated in Dutch-belted rabbits. Following the S/C injection of 1,500 micrograms of AmB, corneal and aqueous levels were determined by bioassay. The highest levels were present in the periphery of debrided corneas at 1 h (90.12 +/- ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199109000-00010
更新日期:1991-09-01 00:00:00
abstract:PURPOSE:To compare the visual results, higher-order aberrations, and corneal biomechanical properties of femtosecond small incision lenticule extraction (SMILE) at depths of 100 and 160 μm. METHODS:A prospective comparative interventional clinical trial of a series of patients who underwent SMILE. In the right eye, a ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000571
更新日期:2015-10-01 00:00:00
abstract:PURPOSE:To examine the applicability of culture supernatant of human amniotic cells on basic fibroblast growth factor (bFGF)-induced corneal neovascularization. METHODS:Human amniotic epithelial and mesenchymal cells (AC) were obtained from human amniotic membranes by digesting with collagenase and maintained in serum...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200201000-00014
更新日期:2002-01-01 00:00:00
abstract::Vitamin A deficiency causing xerophthalmia, although a major public health issue in sub-Saharan Africa, is rarely seen in people living in developed countries. In such cases, it is usually associated with severe malnutrition caused by intestinal disorders, such as celiac disease, pancreatitis, or extensive bowel surge...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181bd9ed5
更新日期:2010-07-01 00:00:00
abstract:PURPOSE:To evaluate adhesion of Acanthamoeba trophozoites to different silicone hydrogel contact lens (SHCL) generations with and without multipurpose contact lens care solution (MPS) treatment. METHODS:Acanthamoeba lugdunensis L3a trophozoites were inoculated onto discs trimmed from SHCLs: first generation, Air Optix...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000788
更新日期:2016-05-01 00:00:00
abstract:PURPOSE:Surgical management of advanced pellucid marginal degeneration is challenging. To correct both corneal thinning and induced corneal astigmatism, we propose a modified intrastromal lamellar sclero-keratoplasty. METHODS:Corneal thinning was mapped using perioperative optical coherence tomography (OCT). Then thro...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000813
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:To report a 16-year-old woman who had peripheral keratitis as a presenting sign of microscopic polyangiitis (MPA), which rapidly progressed to acute renal failure. METHOD:Case report. RESULTS:The patient's vasculitis was diagnosed by renal biopsy, which was evaluated with histologic, immunofluorescence, and e...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200107000-00016
更新日期:2001-07-01 00:00:00
abstract:PURPOSE:This study was designed to determine how patients with pellucid marginal corneal degeneration (PMCD) are managed in a tertiary corneal practice. METHODS:A retrospective chart review of 45 patients with PMCD from a corneal referral practice was performed. Information collected from the medical records included ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000153555.82278.5b
更新日期:2005-07-01 00:00:00
abstract:PURPOSE:To investigate if amniotic membrane incubated with antibiotics could inhibit bacterial growth in vitro. METHODS:Amniotic membrane fragments were incubated with the antibiotics (netilmicin) solution; the washed and drained fragments were either tested after treatment or further incubated in antibiotic-free medi...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000214207.06952.23
更新日期:2006-05-01 00:00:00
abstract:PURPOSE:To investigate the effects of pterygium excision with conjunctival autograft plus corneal polishing on ocular higher-order aberrations (HOAs) and to monitor the changes throughout the first postoperative year. METHODS:A total of 18 eyes of 16 patients with primary pterygium who had an indication for surgical e...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3182431465
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:To assess the efficacy of using a bandage contact lens (BCL) for 3 months for recurrent corneal erosions (RCE) to facilitate epithelial adhesion. METHODS:Retrospective study of patients presented to the Casey Eye Institute (Portland, OR) with RCE after failing at least 6 weeks of medical lubrication therapy. S...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181e84689
更新日期:2011-02-01 00:00:00
abstract:PURPOSE:To compare the efficacy of conjunctival resection versus conjunctival resection with amniotic membrane graft (AMG) in patients with superior limbic keratoconjunctivitis not responsive to medical therapies. METHODS:In a retrospective and comparative study, 16 eyes of 9 patients with long-lasting superior limbic...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181d1d1cc
更新日期:2010-09-01 00:00:00
abstract:PURPOSE:To determine the incidence of postkeratoplasty fungal endophthalmitis and keratitis at the New York Eye and Ear Infirmary. To determine whether there is a relationship between culture-positive corneoscleral donor material and postoperative infection. METHODS:The microbiologic records of corneoscleral donor rim...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico..0000138832.3486.70
更新日期:2005-04-01 00:00:00
abstract:PURPOSE:To present long-term clinical and visual outcomes of patients with Peters anomaly. METHODS:The charts of all patients diagnosed with Peters anomaly from January 2000 to December 2012 were reviewed retrospectively. Peters anomaly was classified as type I (with no lens involvement) or type II (presence of kerato...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002577
更新日期:2020-11-04 00:00:00
abstract:PURPOSE:To report a solitary epibulbar neurofibroma in 2 elderly patients without systemic neurofibromatosis. METHODS:Case reports and literature review. RESULTS:A 67-year-old man presented with a 2-month history of left epibulbar mass. On slit-lamp examination, an 8- × 8-mm amelanotic, translucent, gelatinous, circu...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000370
更新日期:2015-04-01 00:00:00
abstract:PURPOSE:To identify whether histopathologic presence of neovascularization is predictive for allograft failure following penetrating keratoplasty for herpes simplex virus (HSV) keratitis. METHODS:Retrospective, interventional case series of 62 consecutive patients with HSV keratitis who underwent penetrating keratopla...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31819c4e55
更新日期:2009-10-01 00:00:00
abstract:PURPOSE:To assess the keratocyte density (KD) in the cornea of patients with keratoconus not using contact lenses. METHOD:In this pilot study, the eyes (n = 68) of 35 patients with the diagnosis of keratoconus, who did not use contact lenses and the eyes(n = 70) of 35 healthy controls were prospectively examined using...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3182000fd4
更新日期:2011-05-01 00:00:00
abstract:PURPOSE:To assess corneal subbasal nerve density (SBND) and corneal sensitivity (CS) after pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD) without intraoperative 360-degree laser treatment using contact or noncontact panoramic viewing systems. METHODS:This is a prospective study of 34 eyes affe...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001656
更新日期:2018-09-01 00:00:00
abstract::Contact lens (CL) fitting carries the risk of transmitting infectious agents, including adenovirus and Pseudomonas. Therefore, a number of precautions must be observed to ensure safety in the office. Paramount among these is hand washing, both immediately after contact with a patient's eyes and again between patients....
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/00003226-199010001-00017
更新日期:1990-01-01 00:00:00
abstract:PURPOSE:To evaluate the results of trocar-assisted, sutureless, scleral-fixated (SSF) intraocular lens (IOL) implantation combined with penetrating keratoplasty (PKP). METHODS:This study comprised 4 eyes (4 patients) undergoing trocar-assisted SSF-IOL implantation during PKP. The combined technique was performed in 3 ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000944
更新日期:2016-09-01 00:00:00
abstract::The introduction of the excimer laser for keratorefractive surgery in the 1990 s permanently reshaped the treatment landscape for correcting refractive errors, such as myopia, hyperopia, and astigmatism. Until that point, these treatments had relied on less predictable techniques, such as radial keratotomy and automat...
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/ICO.0b013e31826ab0a7
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:To report the diagnosis and management of a patient with a well-tolerated, long-standing retained intracorneal foreign body. METHODS:We describe the case of a 62-year-old man with a 40-year-old retained wood foreign body within the posterior stroma of the cornea. To the authors' knowledge, this is the longest ...
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/ICO.0b013e3181901e1f
更新日期:2009-06-01 00:00:00
abstract::To evaluate an innovative technique for intrastromal air injection to achieve deep anterior lamellar keratoplasty (DALK) with bare Descemet membrane (DM). Thirty-four eyes with anterior corneal pathology, including 27 with keratoconus, underwent DALK. After 400 μm trephination with a suction trephine, ultrasound pachy...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31823f8f2d
更新日期:2012-09-01 00:00:00
abstract:PURPOSE:To determine the effects of single radial or horizontal suture placement in 2-step clear corneal incision (CCI) wound apposition and permeability to particles of India ink. METHODS:Five fresh human globes were included. Two 25-gauge needles connected to a saline solution bag and to a digital manometer were ins...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31824d0d45
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:To present a case of acute idiopathic endotheliitis occurred early after corneal collagen cross-linking (CXL) for progressive keratoconus, and to discuss possible risk factors, causes, and other similar complications in the literature. METHODS:A 24-year-old woman with bilateral keratoconus underwent a corneal ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000110
更新日期:2014-06-01 00:00:00
abstract:PURPOSE:To evaluate trends in the acquisition, storage, and utilization of donated corneal tissue in New Zealand, 2000 to 2009. METHODS:The New Zealand National Eye Bank records were analyzed for the decade January 2000 to December 2009. Variables analyzed included donor demographics (age, sex, and ethnicity), donor s...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318222c3f2
更新日期:2012-05-01 00:00:00
abstract:PURPOSE:To identify risk factors for the occurrence of bleeding complications after enucleation for cornea donation, in order to develop preventive activities to reduce the occurrence of bleeding complications and especially the development of ocular hematomas. METHODS:From all Dutch cornea donors deceased in the year...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181a186fc
更新日期:2009-10-01 00:00:00
abstract:PURPOSE:This study was designed to assess the success of surgical monovision in presbyopic patients. METHODS:A university refractive surgery center retrospective chart review of 82 patients who elected to undergo surgical monovision with laser in situ keratomileusis (LASIK) between January 2000 and January 2003 was co...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000178722.19317.7b
更新日期:2006-02-01 00:00:00
abstract:PURPOSE:To identify and assess the quality of questionnaires used to measure quality of life in keratoconus and guide selection of the most appropriate questionnaire for evaluating the impact of keratoconus. METHODS:A literature search was carried out in Scopus, Web of Science, PubMed, MEDLINE, Cochrane, and PsycINFO ...
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/ICO.0000000000002170
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:The significance of ocular or corneal aberrations may be subject to misinterpretation whenever eyes with different pupil sizes or the application of different Zernike expansion orders are compared. A method is shown that uses simple mathematical interpolation techniques based on normal data to rapidly determine...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318221ce7d
更新日期:2012-03-01 00:00:00