Clinical Profile of Bilateral Microsporidial Keratoconjunctivitis in Healthy Individuals-A Case Series With Long-term Follow-up.

Abstract:

PURPOSE:To describe bilateral microsporidial keratoconjunctivitis in healthy individuals with long-term follow-up. METHODS:Six cases of smear-positive bilateral microsporidial keratoconjunctivitis were diagnosed and followed up during the study period August 2017 to January 2019. Associated risk factors, clinical features, coexistence with adenovirus, clinical course, and recurrence were studied. RESULTS:The mean age was 36.6 years (range: 10-65 years). The mean duration of symptoms was 13.6 days (range: 7-60 days). Predisposing risk factors were present in 4 of 6 cases. The best-corrected visual acuity at presentation was ≥20/30 in all eyes except in one. Typical microsporidial epithelial lesions were seen in only one case. Persistent lesions, clinically resembling Thygeson superficial punctate keratitis in both eyes, were observed in 3 cases. The lesions in 5 eyes resolved with topical lubricants, and the remaining 7 eyes were treated with topical steroids and tacrolimus 0.03%. Complete resolution was seen in 5 eyes at the end of 1 month, and superficial scarring at the last follow-up was seen in 5 eyes. The best-corrected visual acuity was ≤20/30 in 3 eyes at the last follow-up. The mean duration of follow-up was 7.3 months (range: 3-12 mo). CONCLUSIONS:Bilateral microsporidial keratoconjunctivitis in healthy patients has an atypical presentation with prolonged course. Microsporidia could be implicated as potential candidates in the etiopathogenesis of Thygeson superficial punctate keratitis.

journal_name

Cornea

journal_title

Cornea

authors

Mohanty A,Mitra S,Das S,Priyadarshini S,Sahu SK

doi

10.1097/ICO.0000000000002297

subject

Has Abstract

pub_date

2020-07-01 00:00:00

pages

902-908

issue

7

eissn

0277-3740

issn

1536-4798

journal_volume

39

pub_type

杂志文章

相关文献

CORNEA文献大全
  • Toxicity and pharmacokinetics of subconjunctival amphotericin B. An experimental study.

    abstract::The pharmacokinetics and toxicity of subconjunctival (S/C) amphotericin B (AmB) were evaluated in Dutch-belted rabbits. Following the S/C injection of 1,500 micrograms of AmB, corneal and aqueous levels were determined by bioassay. The highest levels were present in the periphery of debrided corneas at 1 h (90.12 +/- ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199109000-00010

    authors: O'Day DM,Smith R,Stevens JB,Williams TE,Robinson RD,Head WS

    更新日期:1991-09-01 00:00:00

  • Contralateral Eye Comparison Between Femtosecond Small Incision Intrastromal Lenticule Extraction at Depths of 100 and 160 μm.

    abstract:PURPOSE:To compare the visual results, higher-order aberrations, and corneal biomechanical properties of femtosecond small incision lenticule extraction (SMILE) at depths of 100 and 160 μm. METHODS:A prospective comparative interventional clinical trial of a series of patients who underwent SMILE. In the right eye, a ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000571

    authors: El-Massry AA,Goweida MB,Shama Ael-S,Elkhawaga MH,Abdalla MF

    更新日期:2015-10-01 00:00:00

  • Suppression of corneal neovascularization by culture supernatant of human amniotic cells.

    abstract:PURPOSE:To examine the applicability of culture supernatant of human amniotic cells on basic fibroblast growth factor (bFGF)-induced corneal neovascularization. METHODS:Human amniotic epithelial and mesenchymal cells (AC) were obtained from human amniotic membranes by digesting with collagenase and maintained in serum...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200201000-00014

    authors: Kobayashi N,Kabuyama Y,Sasaki S,Kato K,Homma Y

    更新日期:2002-01-01 00:00:00

  • Xerophthalmia because of dietary-induced vitamin a deficiency in a young Scottish man.

    abstract::Vitamin A deficiency causing xerophthalmia, although a major public health issue in sub-Saharan Africa, is rarely seen in people living in developed countries. In such cases, it is usually associated with severe malnutrition caused by intestinal disorders, such as celiac disease, pancreatitis, or extensive bowel surge...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181bd9ed5

    authors: Collins CE,Koay P

    更新日期:2010-07-01 00:00:00

  • Adhesion of Acanthamoeba on Silicone Hydrogel Contact Lenses.

    abstract:PURPOSE:To evaluate adhesion of Acanthamoeba trophozoites to different silicone hydrogel contact lens (SHCL) generations with and without multipurpose contact lens care solution (MPS) treatment. METHODS:Acanthamoeba lugdunensis L3a trophozoites were inoculated onto discs trimmed from SHCLs: first generation, Air Optix...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000788

    authors: Lee GH,Lee JE,Park MK,Yu HS

    更新日期:2016-05-01 00:00:00

  • Sclerocorneal Intrastromal Lamellar Keratoplasty for Pellucid Marginal Degeneration.

    abstract:PURPOSE:Surgical management of advanced pellucid marginal degeneration is challenging. To correct both corneal thinning and induced corneal astigmatism, we propose a modified intrastromal lamellar sclero-keratoplasty. METHODS:Corneal thinning was mapped using perioperative optical coherence tomography (OCT). Then thro...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000813

    authors: Guindolet D,Petrovic A,Doan S,Cochereau I,Gabison EE

    更新日期:2016-06-01 00:00:00

  • Peripheral nonulcerative keratitis as a presenting sign of microscopic polyangiitis.

    abstract:PURPOSE:To report a 16-year-old woman who had peripheral keratitis as a presenting sign of microscopic polyangiitis (MPA), which rapidly progressed to acute renal failure. METHOD:Case report. RESULTS:The patient's vasculitis was diagnosed by renal biopsy, which was evaluated with histologic, immunofluorescence, and e...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200107000-00016

    authors: Darlington JK,Mannis MJ,Segal WA,Feiz V,Klug DE

    更新日期:2001-07-01 00:00:00

  • Management of pellucid marginal corneal degeneration.

    abstract:PURPOSE:This study was designed to determine how patients with pellucid marginal corneal degeneration (PMCD) are managed in a tertiary corneal practice. METHODS:A retrospective chart review of 45 patients with PMCD from a corneal referral practice was performed. Information collected from the medical records included ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000153555.82278.5b

    authors: Tzelikis PF,Cohen EJ,Rapuano CJ,Hammersmith KM,Laibson PR

    更新日期:2005-07-01 00:00:00

  • Antimicrobial activity of antibiotic-treated amniotic membrane: An in vitro study.

    abstract:PURPOSE:To investigate if amniotic membrane incubated with antibiotics could inhibit bacterial growth in vitro. METHODS:Amniotic membrane fragments were incubated with the antibiotics (netilmicin) solution; the washed and drained fragments were either tested after treatment or further incubated in antibiotic-free medi...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000214207.06952.23

    authors: Mencucci R,Menchini U,Dei R

    更新日期:2006-05-01 00:00:00

  • The change in ocular higher-order aberrations after pterygium excision with conjunctival autograft: a 1-year prospective clinical trial.

    abstract:PURPOSE:To investigate the effects of pterygium excision with conjunctival autograft plus corneal polishing on ocular higher-order aberrations (HOAs) and to monitor the changes throughout the first postoperative year. METHODS:A total of 18 eyes of 16 patients with primary pterygium who had an indication for surgical e...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3182431465

    authors: Gumus K,Topaktas D,Göktaş A,Karakucuk S,Oner A,Mirza GE

    更新日期:2012-12-01 00:00:00

  • Treatment of recurrent corneal erosion by extended-wear bandage contact lens.

    abstract:PURPOSE:To assess the efficacy of using a bandage contact lens (BCL) for 3 months for recurrent corneal erosions (RCE) to facilitate epithelial adhesion. METHODS:Retrospective study of patients presented to the Casey Eye Institute (Portland, OR) with RCE after failing at least 6 weeks of medical lubrication therapy. S...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181e84689

    authors: Fraunfelder FW,Cabezas M

    更新日期:2011-02-01 00:00:00

  • Conjunctival resection with and without amniotic membrane graft for the treatment of superior limbic keratoconjunctivitis.

    abstract:PURPOSE:To compare the efficacy of conjunctival resection versus conjunctival resection with amniotic membrane graft (AMG) in patients with superior limbic keratoconjunctivitis not responsive to medical therapies. METHODS:In a retrospective and comparative study, 16 eyes of 9 patients with long-lasting superior limbic...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181d1d1cc

    authors: Gris O,Plazas A,Lerma E,Güell JL,Pelegrín L,Elíes D

    更新日期:2010-09-01 00:00:00

  • The incidence of fungal keratitis and endophthalmitis following penetrating keratoplasty.

    abstract:PURPOSE:To determine the incidence of postkeratoplasty fungal endophthalmitis and keratitis at the New York Eye and Ear Infirmary. To determine whether there is a relationship between culture-positive corneoscleral donor material and postoperative infection. METHODS:The microbiologic records of corneoscleral donor rim...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico..0000138832.3486.70

    authors: Keyhani K,Seedor JA,Shah MK,Terraciano AJ,Ritterband DC

    更新日期:2005-04-01 00:00:00

  • Long-Term Visual Outcomes and Clinical Course of Patients With Peters Anomaly.

    abstract:PURPOSE:To present long-term clinical and visual outcomes of patients with Peters anomaly. METHODS:The charts of all patients diagnosed with Peters anomaly from January 2000 to December 2012 were reviewed retrospectively. Peters anomaly was classified as type I (with no lens involvement) or type II (presence of kerato...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002577

    authors: Elbaz U,Strungaru H,Mireskandari K,Stephens D,Ali A

    更新日期:2020-11-04 00:00:00

  • Solitary epibulbar neurofibroma in older adult patients.

    abstract:PURPOSE:To report a solitary epibulbar neurofibroma in 2 elderly patients without systemic neurofibromatosis. METHODS:Case reports and literature review. RESULTS:A 67-year-old man presented with a 2-month history of left epibulbar mass. On slit-lamp examination, an 8- × 8-mm amelanotic, translucent, gelatinous, circu...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000370

    authors: Tanaka TS,Elner VM,Demirci H

    更新日期:2015-04-01 00:00:00

  • Herpes simplex virus keratitis: histopathologic neovascularization and corneal allograft failure.

    abstract:PURPOSE:To identify whether histopathologic presence of neovascularization is predictive for allograft failure following penetrating keratoplasty for herpes simplex virus (HSV) keratitis. METHODS:Retrospective, interventional case series of 62 consecutive patients with HSV keratitis who underwent penetrating keratopla...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31819c4e55

    authors: Garcia DD,Shtein RM,Musch DC,Elner VM

    更新日期:2009-10-01 00:00:00

  • Assessment of keratocyte density in patients with keratoconus not using contact lenses.

    abstract:PURPOSE:To assess the keratocyte density (KD) in the cornea of patients with keratoconus not using contact lenses. METHOD:In this pilot study, the eyes (n = 68) of 35 patients with the diagnosis of keratoconus, who did not use contact lenses and the eyes(n = 70) of 35 healthy controls were prospectively examined using...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3182000fd4

    authors: Timucin OB,Karadag MF,Cinal A

    更新日期:2011-05-01 00:00:00

  • Corneal Subbasal Nerve Density and Sensitivity After Pars Plana Vitrectomy Using Contact or Noncontact Wide-Angle Viewing Systems.

    abstract:PURPOSE:To assess corneal subbasal nerve density (SBND) and corneal sensitivity (CS) after pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD) without intraoperative 360-degree laser treatment using contact or noncontact panoramic viewing systems. METHODS:This is a prospective study of 34 eyes affe...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001656

    authors: Tosi GM,Bacci T,Tarantello A,Martone G,Traversi C,Marigliani D,Cevenini G,Virgili G

    更新日期:2018-09-01 00:00:00

  • Is your office safe? Yes.

    abstract::Contact lens (CL) fitting carries the risk of transmitting infectious agents, including adenovirus and Pseudomonas. Therefore, a number of precautions must be observed to ensure safety in the office. Paramount among these is hand washing, both immediately after contact with a patient's eyes and again between patients....

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/00003226-199010001-00017

    authors: Cohen EJ

    更新日期:1990-01-01 00:00:00

  • Trocar-Assisted, Sutureless, Scleral-Fixated Intraocular Lens Implantation Combined With Penetrating Keratoplasty.

    abstract:PURPOSE:To evaluate the results of trocar-assisted, sutureless, scleral-fixated (SSF) intraocular lens (IOL) implantation combined with penetrating keratoplasty (PKP). METHODS:This study comprised 4 eyes (4 patients) undergoing trocar-assisted SSF-IOL implantation during PKP. The combined technique was performed in 3 ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000944

    authors: Karadag R,Bayramlar H,Azari AA,Rapuano CJ

    更新日期:2016-09-01 00:00:00

  • Wound healing after keratorefractive surgery: review of biological and optical considerations.

    abstract::The introduction of the excimer laser for keratorefractive surgery in the 1990 s permanently reshaped the treatment landscape for correcting refractive errors, such as myopia, hyperopia, and astigmatism. Until that point, these treatments had relied on less predictable techniques, such as radial keratotomy and automat...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/ICO.0b013e31826ab0a7

    authors: Azar DT,Chang JH,Han KY

    更新日期:2012-11-01 00:00:00

  • Well-tolerated intracorneal wood foreign body of 40-year duration.

    abstract:PURPOSE:To report the diagnosis and management of a patient with a well-tolerated, long-standing retained intracorneal foreign body. METHODS:We describe the case of a 62-year-old man with a 40-year-old retained wood foreign body within the posterior stroma of the cornea. To the authors' knowledge, this is the longest ...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/ICO.0b013e3181901e1f

    authors: Covert DJ,Henry CR,Sheth BP

    更新日期:2009-06-01 00:00:00

  • Pachymetry-guided intrastromal air injection ("pachy-bubble") for deep anterior lamellar keratoplasty.

    abstract::To evaluate an innovative technique for intrastromal air injection to achieve deep anterior lamellar keratoplasty (DALK) with bare Descemet membrane (DM). Thirty-four eyes with anterior corneal pathology, including 27 with keratoconus, underwent DALK. After 400 μm trephination with a suction trephine, ultrasound pachy...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31823f8f2d

    authors: Ghanem RC,Ghanem MA

    更新日期:2012-09-01 00:00:00

  • Sutured clear corneal incision: wound apposition and permeability to bacterial-sized particles.

    abstract:PURPOSE:To determine the effects of single radial or horizontal suture placement in 2-step clear corneal incision (CCI) wound apposition and permeability to particles of India ink. METHODS:Five fresh human globes were included. Two 25-gauge needles connected to a saline solution bag and to a digital manometer were ins...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31824d0d45

    authors: May WN,Castro-Combs J,Kashiwabuchi RT,Tattiyakul W,Qureshi-Said S,Hirai F,Behrens A

    更新日期:2013-03-01 00:00:00

  • Acute Idiopathic Endotheliitis Early After Corneal Cross-linking With Riboflavin and Ultraviolet-A.

    abstract:PURPOSE:To present a case of acute idiopathic endotheliitis occurred early after corneal collagen cross-linking (CXL) for progressive keratoconus, and to discuss possible risk factors, causes, and other similar complications in the literature. METHODS:A 24-year-old woman with bilateral keratoconus underwent a corneal ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000110

    authors: Gumus K

    更新日期:2014-06-01 00:00:00

  • The New Zealand National Eye Bank study: trends in the acquisition and storage of corneal tissue over the decade 2000 to 2009.

    abstract:PURPOSE:To evaluate trends in the acquisition, storage, and utilization of donated corneal tissue in New Zealand, 2000 to 2009. METHODS:The New Zealand National Eye Bank records were analyzed for the decade January 2000 to December 2009. Variables analyzed included donor demographics (age, sex, and ethnicity), donor s...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318222c3f2

    authors: Cunningham WJ,Moffatt SL,Brookes NH,Twohill HC,Pendergrast DG,Stewart JM,McGhee CN

    更新日期:2012-05-01 00:00:00

  • Factors involved in the occurrence of bleeding complications after enucleation for cornea donation.

    abstract:PURPOSE:To identify risk factors for the occurrence of bleeding complications after enucleation for cornea donation, in order to develop preventive activities to reduce the occurrence of bleeding complications and especially the development of ocular hematomas. METHODS:From all Dutch cornea donors deceased in the year...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181a186fc

    authors: van Wijk MJ,Nijenhuis MV,Dorrepaal CA,Bokhorst AG

    更新日期:2009-10-01 00:00:00

  • Surgical monovision and monovision reversal in LASIK.

    abstract:PURPOSE:This study was designed to assess the success of surgical monovision in presbyopic patients. METHODS:A university refractive surgery center retrospective chart review of 82 patients who elected to undergo surgical monovision with laser in situ keratomileusis (LASIK) between January 2000 and January 2003 was co...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000178722.19317.7b

    authors: Reilly CD,Lee WB,Alvarenga L,Caspar J,Garcia-Ferrer F,Mannis MJ

    更新日期:2006-02-01 00:00:00

  • Measurement of Quality of Life in Keratoconus.

    abstract:PURPOSE:To identify and assess the quality of questionnaires used to measure quality of life in keratoconus and guide selection of the most appropriate questionnaire for evaluating the impact of keratoconus. METHODS:A literature search was carried out in Scopus, Web of Science, PubMed, MEDLINE, Cochrane, and PsycINFO ...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/ICO.0000000000002170

    authors: Kandel H,Pesudovs K,Watson SL

    更新日期:2020-03-01 00:00:00

  • Method for expressing clinical and statistical significance of ocular and corneal wave front error aberrations.

    abstract:PURPOSE:The significance of ocular or corneal aberrations may be subject to misinterpretation whenever eyes with different pupil sizes or the application of different Zernike expansion orders are compared. A method is shown that uses simple mathematical interpolation techniques based on normal data to rapidly determine...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318221ce7d

    authors: Smolek MK

    更新日期:2012-03-01 00:00:00