Abstract:
PURPOSE:To identify risk factors for the occurrence of bleeding complications after enucleation for cornea donation, in order to develop preventive activities to reduce the occurrence of bleeding complications and especially the development of ocular hematomas. METHODS:From all Dutch cornea donors deceased in the year 2006, donor characteristics, retrieval characteristics, and bleeding complication data were collected. First, univariate relations between donor and retrieval factors and bleeding complications were determined. Then, multivariate logistic regression analysis was used to identify factors significantly associated with bleeding complications. RESULTS:In 114 of the 1173 cornea donors (9.7%), bleeding complications occurred, with ocular hematomas developing in 39 (3.3% of all cornea donors). Donor factors significantly associated with bleeding complications were age [odds ratio (OR) 0.96 (95% CI 0.94-0.97)], weight [OR 1.03 (1.02-1.04)], heart failure [OR 2.10 (1.12-3.94)], thrombocyte aggregation inhibitor use [OR 1.64 (1.02-2.64)], and chronic alcoholic liver disease [OR 2.85 (1.11-7.31)]. The most significant factor associated with bleeding complications was the retrieval sequence. If cornea donation was followed by any other tissue retrieval, the risk of bleeding complications was strongly increased. CONCLUSIONS:: This study shows that the tissue retrieval sequence in multitissue donors is the most important factor associated with the occurrence of bleeding complications. The risk of bleeding and ocular hematoma is lower if cornea donation is performed after all other retrievals. However, if the tissue retrieval sequence is altered, the effect of prolonged postmortem time on corneal quality must be taken into account.
journal_name
Corneajournal_title
Corneaauthors
van Wijk MJ,Nijenhuis MV,Dorrepaal CA,Bokhorst AGdoi
10.1097/ICO.0b013e3181a186fcsubject
Has Abstractpub_date
2009-10-01 00:00:00pages
1014-8issue
9eissn
0277-3740issn
1536-4798journal_volume
28pub_type
杂志文章相关文献
CORNEA文献大全abstract:PURPOSE:To evaluate the association between keratoconus (KC) and immune disorders (IDs). METHODS:A retrospective observational case-control study of all the members in the Central District of Clalit Health Services in Israel who were diagnosed to have KC (years 2000-2007; n = 426) and 1704 age- and gender-matched cont...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181cb410b
更新日期:2010-11-01 00:00:00
abstract:PURPOSE:To report a case of corneal infection with Chrysosporium parvum, a filamentous fungus usually associated with pulmonary infections. METHODS:A 43-year-old Saudi man had a corneal stromal infiltrate and perforation of his left eye. He was treated with a therapeutic penetrating keratoplasty and topical and system...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
abstract::Phacoemulsification has become the most commonly used procedure in cataract surgery owing to the development of new devices and surgical techniques; however, corneal endothelial damage still represents a serious complication. Although several factors are known to cause corneal endothelial damage, effects of irrigating...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000990
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:To report a case of successful medical treatment with oral posaconazole in refractory fungal keratitis caused by Paecilomyces lilacinus. METHODS:Case report. RESULTS:A 57-year-old male, soft contact lens wearer presented with irritation, pain, photophobia, and reduced vision. Slit-lamp examination showed a la...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000143
更新日期:2014-07-01 00:00:00
abstract:PURPOSE:To compare the rebubbling rate and clinical outcomes of Descemet membrane endothelial keratoplasty (DMEK) with 5% sulfur hexafluoride (SF6) gas versus 100% air as a tamponade for graft attachment. METHODS:Retrospective, comparative, interventional case series including 368 consecutive pseudophakic eyes with Fu...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001299
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:Surgical management of advanced pellucid marginal degeneration is challenging. To correct both corneal thinning and induced corneal astigmatism, we propose a modified intrastromal lamellar sclero-keratoplasty. METHODS:Corneal thinning was mapped using perioperative optical coherence tomography (OCT). Then thro...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000813
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:To compare acid-base and oxidation-reduction indicators and to investigate the effect of buffer and temperature on the colorimetric detection of microbial growth in corneal preservation media. METHODS:Corneal preservation media containing gentamicin, without or with HEPES buffer, were prepared with either phen...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200007000-00023
更新日期:2000-07-01 00:00:00
abstract::Penetrating keratoplasty is currently the only treatment for corneal endothelial dysfunction. Although corneal transplantation has a high success rate, a few problems still remain, such as the limited availability of donor grafts, the change in refraction after penetrating keratoplasty, and the higher chance of immune...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199403000-00011
更新日期:1994-03-01 00:00:00
abstract:PURPOSE:The purpose of this report was to describe an uncommon wavelike epitheliopathy after phacoemulsification in a 59-year-old man with well-controlled diabetes mellitus. METHODS:Retrospective case report. RESULTS:A 59-year-old man with a history of well-controlled diabetes mellitus presented to us with irritation...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31804f59f3
更新日期:2007-07-01 00:00:00
abstract:PURPOSE:To assess frequency, associations, and outcomes of full air fill after Descemet membrane endothelial keratoplasty (DMEK). METHODS:This retrospective study reviewed 368 consecutive DMEK cases performed to treat Fuchs dystrophy, bullous keratopathy, or failed keratoplasty. Primary outcomes were air bubble status...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001015
更新日期:2016-11-01 00:00:00
abstract::Epithelium plays a very important structural and functional role in the cornea and conjunctiva. Evaluation of the epithelium is the first step in diagnosing many pathologic states. We have developed a new technique for the in vivo staining of nuclei of corneal and conjunctival epithelium in rabbits and guinea pigs. Se...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract:PURPOSE:To describe the histopathology of the cornea in microphthalmia with linear streaks (MLS) syndrome. METHODS:Two patients with MLS syndrome underwent penetrating keratoplasty. This study describes the histopathology and investigates immunophenotype of the corneal extracellular matrix by using keratan sulfate and...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000611352.03660.a7
更新日期:2008-07-01 00:00:00
abstract:PURPOSE:The 27-kDa heat shock protein (HSP27) has been implicated in wound healing in multiple tissues. We investigated the expression and localization of phosphorylated HSP27 during epithelial wound healing in the murine cornea. METHODS:Corneas of 8- to 10-week-old C57BL6 mice were wounded by epithelial debridement (...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31823f7685
更新日期:2012-07-01 00:00:00
abstract::To evaluate an innovative technique for intrastromal air injection to achieve deep anterior lamellar keratoplasty (DALK) with bare Descemet membrane (DM). Thirty-four eyes with anterior corneal pathology, including 27 with keratoconus, underwent DALK. After 400 μm trephination with a suction trephine, ultrasound pachy...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31823f8f2d
更新日期:2012-09-01 00:00:00
abstract:PURPOSE:To determine whether autologous Descemet stripping endothelial keratoplasty is technically feasible and whether it eliminates the risk of endothelial rejection in "only eyes" at high risk of immunological rejection. METHODS:This is a prospective observational interventional study from 2016 to 2018 with a 24-mo...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002184
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To evaluate the reliability between pneumatonometry intraocular pressure (IOP) measurement in different scleral locations and corneal IOP in a penetrating keratoplasty (PK) setting. Our aim is to validate a method that can potentially be used for patients with keratoprostheses. METHODS:This is a prospective ob...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001314
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:To compare the frequency of positive rim cultures after penetrating keratoplasty using corneas preserved by hypothermic and organ culture storage. To evaluate the influence of standard procurement techniques on the frequency of microbial donor rim contamination. METHODS:Six hundred four donor corneas stored at...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3180415d7e
更新日期:2007-06-01 00:00:00
abstract:PURPOSE:To evaluate the effect of obstructive sleep apnea-hypopnea syndrome (OSAHS) on the meibomian glands, ocular surface, and tear parameters. METHODS:The study included 59 individuals (32 subjects with OSAHS, 27 control subjects) who underwent polysomnography in the Chest Diseases Clinic. The right eyes of all ind...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002252
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:To assess the influence of donor characteristics on the outcome of anterior lamellar keratoplasty (ALK) and to evaluate whether corneal donor tissue considered unsuitable for penetrating or posterior lamellar keratoplasty due to poor endothelial condition may be safely used for ALK. METHODS:Institutional setti...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318285c8b4
更新日期:2013-08-01 00:00:00
abstract:PURPOSE:To evaluate the results of a combined approach of cicatrix lysis, intraoperative mitomycin C (MMC) application, oral mucosal transplantation (OMT), and amniotic membrane transplantation (AMT) for surgery of severe symblepharon. METHODS:This prospective study included 32 eyes with severe symblepharon in which a...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318247983d
更新日期:2013-02-01 00:00:00
abstract:PURPOSE:To assess the effects of corneal collagen cross-linking (CXL) on contrast sensitivity (CS), visual acuity, and corneal topography investigating possible predictors of efficacy. METHODS:Sixty-eight eyes of 34 patients with progressive keratoconus were enrolled in this prospective study. CXL was performed in one...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31826672e2
更新日期:2013-05-01 00:00:00
abstract::We report a case of a patient with Down's syndrome and keratoconus with acute hydrops who was incidentally noted to have Axenfeld's anomaly. We also review the systemic abnormalities associated with Axenfeld's anomaly and the implications of the diagnosis. To our knowledge, Axenfeld's anomaly has not previously been r...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199203000-00012
更新日期:1992-03-01 00:00:00
abstract:PURPOSE:The aim of this study was to determine the effect of nicergoline in patients with neurotrophic keratopathy. METHODS:This is a prospective, noncomparative interventional study. The study included 27 eyes of 24 patients with neurotrophic keratopathy who were unresponsive to conventional therapy. Patients were tr...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000348
更新日期:2015-03-01 00:00:00
abstract::Corneal neovascularization complicates many anterior segment diseases. Corneal laser photocoagulation using yellow light (577 nm) has been shown to reduce corneal neovascularization. No histopathologic studies of the effects of this treatment on the eye have been reported, however. Target (cornea) and nontarget (iris,...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199305000-00001
更新日期:1993-05-01 00:00:00
abstract:PURPOSE:To report on a patient in whom hyperopic Implantable Collamer Lenses (ICL, STAAR Surgical, Nidau, Switzerland) and limbal relaxing incisions have been beneficial for the correction of hyperopic astigmatism after laser in situ keratomileusis (LASIK). METHODS:The 48-year-old man had undergone LASIK to correct hi...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31818a7de3
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:To report the outcomes of Boston keratoprosthesis (K-pro) type I implantation for congenital aniridia. METHODS:A retrospective review of the medical records of every patient with congenital aniridia who underwent Boston K-pro type I implantation at the University of Iowa Hospitals and Clinics from January 1, 2...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318281724a
更新日期:2013-07-01 00:00:00
abstract:PURPOSE:To analyze whether plasma rich in growth factors (PRGF) eye drops preserve their biological characteristics and activity after storage for 3 and 6 months at -20°C, at 4°C, and at room temperature for 72 hours, compared with fresh samples (t0). METHODS:Blood from 6 healthy donors was harvested and centrifuged t...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000489
更新日期:2015-09-01 00:00:00
abstract:PURPOSE:To report an unusual case of epithelial ingrowth after phacoemulsification with posterior chamber intraocular lens implantation in a patient with recurrent pterygium, along with confocal microscopy findings of epithelial ingrowth. METHODS:This is a case report and review of the literature. RESULTS:A healthy 6...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002158
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To describe the clinical features, histopathology, surgical management and possible etiopathogenesis of corneoscleral epithelial cysts. METHODS:Three patients with corneoscleral epithelial cysts underwent surgical ablation of the cysts. Material obtained during surgery was subjected to histopathologic analysis...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199807000-00018
更新日期:1998-07-01 00:00:00
abstract:PURPOSE:The depth of corneal crosslinking (CXL) does not seem homogeneous within the treatment area but shows a reduction toward the periphery of the cornea. This study was undertaken to investigate this reduction effect and to look for possible solutions. METHODS:Ten corneas were investigated by means of an optical c...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318269059b
更新日期:2013-02-01 00:00:00