Biomicroscopic and histopathologic observations after corneal laser photocoagulation in a rabbit model of corneal neovascularization.

Abstract:

:Corneal neovascularization complicates many anterior segment diseases. Corneal laser photocoagulation using yellow light (577 nm) has been shown to reduce corneal neovascularization. No histopathologic studies of the effects of this treatment on the eye have been reported, however. Target (cornea) and nontarget (iris, lens, retina, and choroid) ocular tissue were studied 1, 24, and 48 h and 5 days after yellow dye corneal laser photocoagulation in a rabbit model of corneal neovascularization. Biomicroscopic examination of the corneas revealed intracorneal hemorrhage in five of 24 (21%) eyes of nonpigmented rabbits. Faint lenticular opacities were observed in two eyes of pigmented rabbits 24 h after laser treatment. Histopathologic examination revealed increased cellularity (neutrophils) (p < 0.005) in the cornea, increasing from 1 h after treatment, peaking 24 h later, and persisting past 5 days. Distortion of the corneal lamellae by red blood cells occurred in eyes in which intracorneal hemorrhage developed. These results indicate that corneal laser photocoagulation using yellow light is a relatively safe procedure for reducing corneal neovascularization.

journal_name

Cornea

journal_title

Cornea

authors

Hemady RK,Baer JC,Foster CS

doi

10.1097/00003226-199305000-00001

subject

Has Abstract

pub_date

1993-05-01 00:00:00

pages

185-90

issue

3

eissn

0277-3740

issn

1536-4798

journal_volume

12

pub_type

杂志文章

相关文献

CORNEA文献大全
  • Effect of fourth-generation fluoroquinolones on the healing rate of corneal erosions in an animal model.

    abstract:PURPOSE:To compare the rate of epithelial healing of corneal erosion in an animal model with 2 commercial formulations of fourth-generation fluoroquinolones: 0.3% gatifloxacin and 0.5% moxifloxacin. METHODS:Corneal erosions, 6 mm in diameter, were created in 28 rabbit eyes. The rabbits were randomized to receive topic...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318041f08e

    authors: Barequet IS,Habot-Wilner Z,Lavinsky F,Ziv H,Belkin M,Rosner M

    更新日期:2007-06-01 00:00:00

  • Evaluation of prior photorefractive keratectomy in donor tissue.

    abstract:PURPOSE:To describe a case in which an eye donor had prior bilateral photorefractive keratectomies and to elucidate possible methods of evaluation and screening of donor tissue. METHODS:Case report. A 62-year-old eye donor was reported to have received radial keratotomy before his death. Further investigation by the e...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199905000-00018

    authors: Terry MA,Ousley PJ,Rich LF,Wilson DJ

    更新日期:1999-05-01 00:00:00

  • Mutation analysis of CHST6 gene in Chinese patients with macular corneal dystrophy.

    abstract:PURPOSE:To examine the carbohydrate sulfotransferase 6 (CHST6) gene in Chinese patients with macular corneal dystrophy (MCD). METHODS:Nineteen unrelated Chinese families with MCD, including 24 patients and 3 unaffected relatives, were examined. Genomic DNA was extracted from peripheral blood leukocytes. The coding reg...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181ca2e74

    authors: Liu Z,Tian X,Iida N,Fujiki K,Xie P,Wang W,Ma Z,Kanai A,Murakami A

    更新日期:2010-08-01 00:00:00

  • Hemangiogenesis and lymphangiogenesis in corneal pathology.

    abstract:PURPOSE:We characterized the presence of hemangiogenesis (HA) and lymphangiogenesis (LA) in human corneal specimens exhibiting 13 underlying pathologies. METHODS:Human corneal specimens were obtained from consenting subjects (n = 2 or n = 3 for each pathology; total sample size, n = 35). The pathological specimens wer...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31821dd986

    authors: Tshionyi M,Shay E,Lunde E,Lin A,Han KY,Jain S,Chang JH,Azar DT

    更新日期:2012-01-01 00:00:00

  • Efficacy of Omega-3 Fatty Acid Supplementation for Treatment of Dry Eye Disease: A Meta-Analysis of Randomized Clinical Trials.

    abstract:PURPOSE:To assess whether omega-3 fatty acid (FA) supplementation is more efficacious than placebo in amelioration of signs and symptoms of dry eye disease. METHODS:We performed a systematic literature search in PubMed, Scopus, Web of Science, and Cochrane Central Register of Controlled Trials databases. We included r...

    journal_title:Cornea

    pub_type: 杂志文章,meta分析

    doi:10.1097/ICO.0000000000001884

    authors: Giannaccare G,Pellegrini M,Sebastiani S,Bernabei F,Roda M,Taroni L,Versura P,Campos EC

    更新日期:2019-05-01 00:00:00

  • Modified Ruiz procedure for reducing high astigmatism after penetrating keratoplasty.

    abstract:PURPOSE:To evaluate the refractive, keratometric, and visual outcomes of a modified Ruiz procedure in patients with high astigmatism after penetrating keratoplasty (PKP). METHODS:Retrospective cohort study with 26 eyes of 24 patients. A modified Ruiz incision pattern was used. Two paired arcuate incisions, centered on...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318153f241

    authors: Zuberbuhler B,Agrawal A,Gale R,Kipioti T,Gauba V,Noble B

    更新日期:2007-12-01 00:00:00

  • Noncontact Evaluation of Corneal Grafts: Swept-Source Fourier Domain OCT Versus High-Resolution Scheimpflug Imaging.

    abstract:PURPOSE:To study the reliability and repeatability of anterior segment measurements in patients who underwent penetrating keratoplasty with swept light source Fourier domain anterior segment optical coherence tomography (SS-OCT) in comparison with a high-resolution Scheimpflug camera. METHODS:Keratometry (K) and eleva...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001133

    authors: Szalai E,Németh G,Hassan Z,Módis L Jr

    更新日期:2017-04-01 00:00:00

  • Lamina Cribrosa Thickness in Patients With Keratoconus.

    abstract:PURPOSE:To evaluate the thickness and depth of lamina cribrosa (LC) in the optic nerve head region of the eyes in patients with nonglaucomatous keratoconus and to compare the thickness and depth with those of age-matched controls. METHODS:This was a cross-sectional, observational study comprising 45 patients with kera...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001379

    authors: Akkaya S,Küçük B

    更新日期:2017-12-01 00:00:00

  • The brilliant beauty of the eye: light reflex from the cornea and tear film.

    abstract:PURPOSE:Light reflex from the cornea and tear film as contributors to beautiful eyes ("eye sparkling") are reviewed. METHODS:A systematic literature review was conducted using "Purkinje-Sanson image," "corneal light reflex," "corneal topography," "corneal wavefront aberration," and "tear interference image" as search ...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/01.ico.0000247219.18295.5e

    authors: Goto E

    更新日期:2006-12-01 00:00:00

  • Corneal Endothelial Morphology and Thickness Alterations in Patients With Severe Obstructive Sleep Apnea-Hypopnea Syndrome.

    abstract:PURPOSE:To investigate central endothelial cell density (ECD), morphology, and central corneal thickness (CCT) in patients newly diagnosed with severe obstructive sleep apnea-hypopnea syndrome (OSAHS) and to determine the correlation between these parameters and OSAHS severity. METHODS:This prospective, comparative ca...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002373

    authors: Chalkiadaki E,Andreanos K,Florou C,Droutsas K,Maniou C,Amfilochiou A,Georgalas I,Papaconstantinou D,Koutsandrea C

    更新日期:2021-01-01 00:00:00

  • Peripheral ulcerative keratitis after Salmonella gastroenteritis.

    abstract:PURPOSE:To describe a case of bilateral peripheral ulcerative keratitis after Salmonella gastroenteritis. METHODS:Case report with description of treatment and outcome. RESULTS:The peripheral ulcerative keratitis gradually resolved in both eyes after appropriate systemic antibiotic therapy and local ocular care. CON...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199811000-00017

    authors: Yang J,Baltatzis S,Foster CS

    更新日期:1998-11-01 00:00:00

  • Posterior Amorphous Corneal Dystrophy Associated With Keratoglobus: A Case Report.

    abstract:PURPOSE:Posterior amorphous corneal dystrophy (PACD) is a rare disorder characterized by sheet-like opacification of the posterior corneal stroma, corneal thinning, and decreased corneal curvature. It is not known to be associated with progressive corneal ectasia. In this report, we examine the course of a patient with...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001304

    authors: Fay J,Herzlich AA,Florakis GJ

    更新日期:2017-12-01 00:00:00

  • Randomized clinical study for comparative evaluation of fourth-generation fluoroquinolones with the combination of fortified antibiotics in the treatment of bacterial corneal ulcers.

    abstract:PURPOSE:Comparative evaluation of efficacy of monotherapy with moxifloxacin (0.5%) or gatifloxacin (0.3%) with combination therapy of cefazolin (5%) and tobramycin (1.3%) in treatment of bacterial corneal ulcers. METHODS:Patients diagnosed with bacterial keratitis (ulcer diameter 2-8 mm) were randomized to 1 of the 3 ...

    journal_title:Cornea

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/ICO.0b013e3181ca2ba3

    authors: Shah VM,Tandon R,Satpathy G,Nayak N,Chawla B,Agarwal T,Sharma N,Titiyal JS,Vajpayee RB

    更新日期:2010-07-01 00:00:00

  • Accuracy and precision of the amadeus microkeratome in producing LASIK flaps.

    abstract:PURPOSE:To evaluate the accuracy and precision of corneal flap thickness following laser in situ keratomileusis (LASIK) performed using the 140-, 160-, and 180-microm heads for the Amadeus microkeratome (AMO, Irvine, CA). SETTING:The study took place at the Cullen Eye Institute, Baylor College of Medicine, Houston. M...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200308000-00003

    authors: Jackson DW,Wang L,Koch DD

    更新日期:2003-08-01 00:00:00

  • Epithelial Ingrowth Post Phacoemulsification in a Case of Recurrent Pterygium.

    abstract:PURPOSE:To report an unusual case of epithelial ingrowth after phacoemulsification with posterior chamber intraocular lens implantation in a patient with recurrent pterygium, along with confocal microscopy findings of epithelial ingrowth. METHODS:This is a case report and review of the literature. RESULTS:A healthy 6...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002158

    authors: Khurana S,Gupta PC,R B,Sharma VK,Ram J

    更新日期:2020-01-01 00:00:00

  • New-onset herpes simplex virus keratitis after cataract surgery.

    abstract::We report the case of a 34-year-old man who had uncomplicated cataract surgery in his left eye. Medical history was significant for atopic dermatitis, requiring oral immunosuppressive medications. Two days after the surgery, the patient presented with pain, photophobia, decreased vision, and a small corneal abrasion. ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318182262c

    authors: Patel NN,Teng CC,Sperber LT,Dodick JM

    更新日期:2009-01-01 00:00:00

  • Evaluation of the Safety and Efficacy of a Low-Temperature Plasma Surgical System for Pterygium.

    abstract:PURPOSE:Surgical excision is the standard treatment for pterygium. This study was conducted to evaluate the safety and efficacy of a novel technique using low-temperature plasma (LTP) for excision and hemostasis in pterygium surgery. METHODS:A prospective, comparative, and randomized clinical trial was conducted on 60...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002487

    authors: Huang H,Li S,Zhong J,Wang B,Peng L,Deng Y,Wang M,Yuan J

    更新日期:2020-12-01 00:00:00

  • Clinical treatment of ocular demodecosis by lid scrub with tea tree oil.

    abstract:PURPOSE:To report clinical outcome of treating ocular demodecosis by lid scrub with tea tree oil (TTO). METHODS:Retrospective review of clinical results in 11 patients with ocular Demodex who received weekly lid scrub with 50% TTO combined with daily lid hygiene with tea tree shampoo. RESULTS:These 11 patients also h...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000244870.62384.79

    authors: Gao YY,Di Pascuale MA,Elizondo A,Tseng SC

    更新日期:2007-02-01 00:00:00

  • In vitro comparison of Chen medium and Optisol-GS medium for human corneal storage.

    abstract:PURPOSE:To compare paired human corneas after storage at 4 degrees C in Chen medium (CM) and Optisol-GS medium (OM) for 7, 10, 14, and 21 days. METHODS:One cornea of each pair from nine human donors was randomly stored in either CM or OM, with its mate cornea stored in the other medium. Three pairs of corneas were sto...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200011000-00005

    authors: Nelson LR,Hodge DO,Bourne WM

    更新日期:2000-11-01 00:00:00

  • Endophthalmitis in Advanced Microbial Keratitis: Risk Factors and Examination Findings.

    abstract:PURPOSE:To evaluate clinical and ultrasonographic findings associated with advanced microbial keratitis with concurrent endophthalmitis. METHODS:We performed a retrospective analytical study of patients with severe microbial keratitis who underwent ocular ultrasonography for possible endophthalmitis at our institution...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002349

    authors: Christopher KL,Hood CT,Mian SI,Ayres B

    更新日期:2020-09-01 00:00:00

  • Gentamicin-resistant pseudomonal infection. Rationale for a redefinition of ophthalmic antimicrobial sensitivities.

    abstract::Eight pseudomonal species were involved in 106 invasive infections of the eye; all were community acquired. Eighteen percent of the total and 9% of the Pseudomonas aeruginosa strains were gentamicin resistant, as defined using conventional criteria. All 10 cases of "resistant" pseudomonal (nine P. aeruginosa) keratiti...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Ormerod LD,Heseltine PN,Alfonso E,Becker MI,Kenyon KR,Baerveldt G,Smith RE

    更新日期:1989-09-01 00:00:00

  • Posterior scleritis secondary to Pseudomonas aeruginosa keratitis.

    abstract:PURPOSE:To report a case of Pseudomonas aeruginosa keratitis that progressed to posterior scleritis. METHODS:Observational case report. RESULTS:A 64-year-old woman was treated for P. aeruginosa keratitis. Twelve days later, she was diagnosed with posterior scleritis and treated with oral ciprofloxacin. Her condition ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000154403.78838.90

    authors: Fahim K,Houghton O,Dastjerdi M,Mian SI

    更新日期:2005-10-01 00:00:00

  • Effectiveness of topical infliximab in a mouse model of experimental dry eye.

    abstract:PURPOSE:To investigate the efficacy of a topical anti-tumor necrosis factor-α agent, infliximab, in a mouse model of experimental dry eye (EDE). METHODS:EDE was induced in C57BL/6 mice, with or without topical treatment consisting of balanced salt solution or 0.001%, 0.01%, or 0.1% infliximab solutions. Tear volume an...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31826a80ea

    authors: Li Z,Choi W,Oh HJ,Yoon KC

    更新日期:2012-11-01 00:00:00

  • Robotically Assisted Pterygium Surgery: First Human Case.

    abstract:PURPOSE:Little research has been done on robotic ocular microsurgery. This study aims to demonstrate the feasibility of pterygium surgery using a robotic surgical system. METHODS:Robot-assisted pterygium surgery was performed on a 73-year-old patient with nasal and temporal pterygia using the DaVinci Si HD robotic Sur...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000561

    authors: Bourcier T,Chammas J,Becmeur PH,Danan J,Sauer A,Gaucher D,Liverneaux P,Mutter D

    更新日期:2015-10-01 00:00:00

  • Endothelial keratoplasty without Descemet stripping after failed penetrating keratoplasty.

    abstract:PURPOSE:To evaluate outcomes of endothelial keratoplasty (EK) without Descemet membrane stripping for treatment of failed penetrating keratoplasty (PKP). METHODS:Retrospective cohort study of all eyes that underwent EK without Descemet membrane stripping for failed PKP at one institution between May 2008 and June 2010...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31823f8c59

    authors: Heitor de Paula F,Kamyar R,Shtein RM,Sugar A,Mian SI

    更新日期:2012-06-01 00:00:00

  • Colorimetric indicators of microbial contamination in corneal preservation medium.

    abstract:PURPOSE:To compare acid-base and oxidation-reduction indicators and to investigate the effect of buffer and temperature on the colorimetric detection of microbial growth in corneal preservation media. METHODS:Corneal preservation media containing gentamicin, without or with HEPES buffer, were prepared with either phen...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200007000-00023

    authors: Chu YI,Penland RL,Wilhelmus KR

    更新日期:2000-07-01 00:00:00

  • Three decades of corneal transplantation: indications and patient characteristics.

    abstract:PURPOSE:To review the indications and patient characteristics for penetrating keratoplasty (PKP). METHODS:Retrospective review of records at the Pathology Service, Department of Ophthalmology, University of Toronto from 1964 to 1997. RESULTS:The 6,222 records were reviewed. The leading indications for PKP were regraf...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200001000-00002

    authors: Maeno A,Naor J,Lee HM,Hunter WS,Rootman DS

    更新日期:2000-01-01 00:00:00

  • Impression cytology study of conjunctival epithelial phenotypes on the healing ocular surface after pterygium excision.

    abstract:PURPOSE:To compare the process of conjunctival epithelial regeneration after three types of pterygium excision procedures. METHODS:Thirty-eight patients (45 eyes) with primary pterygium were randomly assigned to a bare-sclera procedure (group 1, 15 eyes of 12 patients), bare-sclera with intraoperative mitomycin C (MMC...

    journal_title:Cornea

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00003226-200104000-00002

    authors: Tseng SH,Chen YT,Cheng HC,Huang FC,Lee SC,Chen FK

    更新日期:2001-04-01 00:00:00

  • A case of infectious crystalline keratopathy occurring long after penetrating keratoplasty.

    abstract:PURPOSE:To report a 64-year-old woman's case of infectious crystalline keratopathy (ICK) that occurred 9 years after the penetrating keratoplasty (PKP). METHODS:This study includes clinical history and histopathologic findings of the case. RESULTS:As historic background, the patient underwent PKP for lattice dystroph...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199801000-00018

    authors: Matsumoto A,Sano Y,Nishida K,Yokoi N,Hara J,Kinoshita S

    更新日期:1998-01-01 00:00:00

  • A review of relative risks associated with four types of contact lenses.

    abstract::This paper reviews the data of Frank et al. in the light of increasing concern over the safety of contact lenses used for extended wear. Relative risks were calculated for four types of contact lenses (CLs): extended wear soft, daily wear soft, rigid gas-permeable (RGP), and polymethylmethacrylate (PMMA) lenses--worn ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199010001-00024

    authors: Bailey CS

    更新日期:1990-01-01 00:00:00