Experimental transplantation of corneal epithelium-like cells induced by Pax6 gene transfection of mouse embryonic stem cells.

abstract：:Corneal neovascularization complicates many anterior segment diseases. Corneal laser photocoagulation using yellow light (577 nm) has been shown to reduce corneal neovascularization. No histopathologic studies of the effects of this treatment on the eye have been reported, however. Target (cornea) and nontarget (iris,...

journal_title：Cornea

authors： Hemady RK,Baer JC,Foster CS

更新日期：1993-05-01 00:00:00

abstract：PURPOSE:To identify and assess the quality of questionnaires used to measure quality of life in keratoconus and guide selection of the most appropriate questionnaire for evaluating the impact of keratoconus. METHODS:A literature search was carried out in Scopus, Web of Science, PubMed, MEDLINE, Cochrane, and PsycINFO ...

journal_title：Cornea

authors： Kandel H,Pesudovs K,Watson SL

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:To characterize the clinical presentation of limbal stem cell deficiency (LSCD) associated with glaucoma surgeries. METHODS:This is a retrospective cross-sectional study of patients with LSCD and glaucoma who presented to the Stein Eye Institute at the University of California, Los Angeles, between 2009 and 20...

journal_title：Cornea

authors： Sun Y,Yung M,Huang L,Tseng C,Deng SX

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of supratarsal triamcinolone injection in the treatment of superior limbic keratoconjunctivitis (SLK). METHODS:Forty eyes of 20 patients were diagnosed with SLK. All eyes with long-standing severe ocular irritation unresponsive to topical steroid and artificial tears were treated with ...

journal_title：Cornea

authors： Shen YC,Wang CY,Tsai HY,Lee YF

更新日期：2007-05-01 00:00:00

abstract：PURPOSE:To determine the effect of mitomycin C (MMC) on the corneal endothelium after primary pterygium surgery. METHODS:This prospective, interventional, nonrandomized, observer-masked study included 46 consecutive patients (51 eyes) with primary pterygium. The bare sclera technique with 1-minute application of 0.02%...

journal_title：Cornea

authors： Pérez-Rico C,Benítez-Herreros J,Montes-Mollón MA,Germain F,Castro-Rebollo M,Gómez-SanGil Y,Paz-Moreno J,Teus MA

更新日期：2009-12-01 00:00:00

abstract：:The following is a case report of a 61-year-old woman with a 10-year history of pemphigus vulgaris, successfully treated with steroids and cytotoxic agents. The patient developed severe herpes zoster ophthalmicus, complicated by a staph-indolent corneal ulcer. This case illustrates several of the many unfortunate opht...

journal_title：Cornea

authors： Webb RM,Duke MA

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:To determine keratometric astigmatism (KA), posterior corneal astigmatism (PCA), and total corneal astigmatism (TCA) in 951 normal eyes, to establish a model for estimating TCA from anterior corneal data, and to test this method in a new group of eyes with toric intraocular lenses (TIOLs). METHODS:We used a Pe...

journal_title：Cornea

authors： Næser K,Savini G,Bregnhøj JF

更新日期：2017-07-01 00:00:00

abstract：:Salzmann's nodular degeneration is a rare, noninflammatory, slowly progressive, degenerative condition. Bluish-white nodules raised above the surface of the cornea characterize it. It has usually developed in corneas with a history of phlyctenulosis, trachoma, vernal keratoconjunctivitis, measles, scarlet fever, and v...

journal_title：Cornea

authors： Das S,Link B,Seitz B

更新日期：2005-10-01 00:00:00

abstract：PURPOSE:To report a case of Listeria monocytogenes sclerokeratitis and to review the literature. METHODS:Case report. RESULTS:A 25-year-old non-contact lens-wearing male rugby player was referred with progressive infective sclerokeratitis unresponsive to topical antivirals and antibiotics. On examination, visual acui...

journal_title：Cornea

authors： Tay E,Rajan M,Tuft S

更新日期：2008-09-01 00:00:00

abstract：PURPOSE:To establish determining factors for fast corneal sensitivity (CS) recovery after pterygium excision. METHODS:Thirty-two eyes of 14 males and 18 females with primary nasal pterygium were recruited. Differences in CS (in the 4 quadrants and the center using a Cochet-Bonnet esthesiometer), pterygium corneal area...

journal_title：Cornea

authors： Julio G,Campos P,Pujol P,Munguia A,Mas-Aixala E

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:Evaluation of contact lens-induced cytologic changes on the conjunctival surface. METHODS:Fifty eyes of 25 patients wearing soft or rigid gas-permeable contact lenses, and 50 healthy eyes of 25 control subjects were examined with conjunctival impression cytology. Of the patients wearing contact lenses, 40% did...

journal_title：Cornea

authors： Adar S,Kanpolat A,Sürücü S,Ucakhan OO

更新日期：1997-05-01 00:00:00

abstract：PURPOSE:To determine how ocular surface epithelium adjusts to an increase in cell replication after treatment with the opioid antagonist naltrexone (NTX). METHODS:Adult male rats were given twice daily injections of 30 mg/kg NTX or vehicle for 7 days. Outcomes of NTX administration included DNA synthesis (monitored wi...

journal_title：Cornea

authors： Zagon IS,Sassani JW,McLaughlin PJ

更新日期：2006-08-01 00:00:00

abstract：PURPOSE:The study aimed to determine whether detectable concentrations of colchicine are present in the tear fluid of treated patients with familial Mediterranean fever (FMF) and thus demonstrate a possible route by which colchicine reaches the corneal surface. METHODS:Tear fluid samples (50-100 microL) were collected...

journal_title：Cornea

authors： Leibovitch I,Alster Y,Scherrmann JM,Azmon B,Barequet IS,Livneh A,O'Brien TP,Lazar M,Loewenstein A

更新日期：2003-04-01 00:00:00

abstract：PURPOSE:Laser-assisted epilation of eyebrow hair has become a common practice, but a number of ocular complications can occur. We report the cases of 2 patients who had unilateral anterior uveitis after having undergone laser removal of eyebrow hair. METHODS:This report describes 2 patients who experienced eye pain, p...

journal_title：Cornea

authors： Gunes A,Yasar C,Tok L,Tok O

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To compare the rate of epithelial healing of corneal erosion in an animal model with 2 commercial formulations of fourth-generation fluoroquinolones: 0.3% gatifloxacin and 0.5% moxifloxacin. METHODS:Corneal erosions, 6 mm in diameter, were created in 28 rabbit eyes. The rabbits were randomized to receive topic...

journal_title：Cornea

authors： Barequet IS,Habot-Wilner Z,Lavinsky F,Ziv H,Belkin M,Rosner M

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:To evaluate the potential of human anterior lens capsule (HALC) as a carrier matrix for cultivating and transplanting human corneal endothelial cells (HCECs). METHODS:HALCs obtained from 12 patients during cataract surgery were exposed to enzyme digestion to dissolve the lens epithelium and were plated with th...

journal_title：Cornea

authors： Yoeruek E,Saygili O,Spitzer MS,Tatar O,Bartz-Schmidt KU,Szurman P

更新日期：2009-05-01 00:00:00

abstract：PURPOSE:To report a case of epithelial ingrowth (downgrowth) occurring in a phakic corneal transplant patient after traumatic wound dehiscence with iris prolapse that was successfully eradicated with early surgical intervention. METHODS:Interventional case report of a 70-year-old monocular, phakic patient who develope...

journal_title：Cornea

authors： Nagra PK,Raber IM

更新日期：2003-03-01 00:00:00

abstract：PURPOSE:To determine whether there is an association between keratoconus and personality attributes including obsessionality traits. METHODS:We reviewed all charts in the regional contact lens clinic, identifying patients who had attended from January 1997 to January 2000 and had a diagnosis of either keratoconus or m...

journal_title：Cornea

authors： Cooke CA,Cooper C,Dowds E,Frazer DG,Jackson AJ

更新日期：2003-04-01 00:00:00

abstract：PURPOSE:We sought to illustrate the difficulty in managing uncommon, pigmented mold-related corneal ulceration and to highlight the role of itraconazole in treating these patients. METHOD:We describe the management and clinical course of a patient with a recurring corneal infection caused by Fonsecaea pedrosoi and dis...

journal_title：Cornea

authors： Barton K,Miller D,Pflugfelder SC

更新日期：1997-03-01 00:00:00

abstract：PURPOSE:The effects of repeated intravitreal aflibercept injection (IAI) on the corneal endothelium were studied in patients with unilateral neovascular age-related macular degeneration. METHODS:RE-VIEW was a phase 4, open-label, single-arm, multicenter study. Patients received IAI every 8 weeks after 3 monthly doses....

journal_title：Cornea

authors： Lass JH,Benetz BA,Menegay HJ,Tsipis CP,Cook JC,Boyer DS,Singer M,Erickson K,Saroj N,Vitti R,Chu KW,Moini H,Soo Y,Cheng Y

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:We report 2 cases in which cataract extraction with a foldable acrylic toric intraocular lens (IOL) implantation was used to correct (irregular) corneal astigmatism in patients with keratoconus and cataract. METHODS:Case 1 was a 78-year-old man with cataract and keratoconus in the left eye. He underwent phacoe...

journal_title：Cornea

authors： Visser N,Gast ST,Bauer NJ,Nuijts RM

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:The purpose of this study was to report the first case of fungal keratitis resulting from Thielavia sp. METHODS:We conducted a retrospective chart review. RESULTS:A 10-year old girl presented 2 weeks after ocular plant injury with pain and corneal stromal infiltration with central ulceration and ill-defined m...

journal_title：Cornea

authors： Theoulakis P,Goldblum D,Zimmerli S,Muehlethaler K,Frueh BE

更新日期：2009-10-01 00:00:00

abstract：:The introduction of the excimer laser for keratorefractive surgery in the 1990 s permanently reshaped the treatment landscape for correcting refractive errors, such as myopia, hyperopia, and astigmatism. Until that point, these treatments had relied on less predictable techniques, such as radial keratotomy and automat...

journal_title：Cornea

authors： Azar DT,Chang JH,Han KY

更新日期：2012-11-01 00:00:00

abstract：PURPOSE:To describe a case of bilateral peripheral ulcerative keratitis after Salmonella gastroenteritis. METHODS:Case report with description of treatment and outcome. RESULTS:The peripheral ulcerative keratitis gradually resolved in both eyes after appropriate systemic antibiotic therapy and local ocular care. CON...

journal_title：Cornea

authors： Yang J,Baltatzis S,Foster CS

更新日期：1998-11-01 00:00:00

abstract：PURPOSE:To determine the stability of the laser in situ keratomileusis (LASIK) flap in a rabbit model when subjected to vertical acceleration at nine times the force of gravity (+9 Gz) in an aircraft cockpit ejection simulator. METHODS:Thirty-six eyes from 25 New Zealand white rabbits underwent LASIK flap creation wit...

journal_title：Cornea

authors： Goodman RL,Johnson DA,Dillon H,Edelhauser HF,Waller SG

更新日期：2003-03-01 00:00:00

abstract：:Two patients developed graft versus host disease (GvHD) following allogeneic bone marrow transplantation for leukemia. One patient developed acute GvHD 12 days after transplantation, and the second developed chronic GvHD 100 days after transplantation. Tear analysis and conjunctival impression cytology were performed....

journal_title：Cornea

authors： Heitman KF,Lam KW,Maskin SL,Yee RW,Lawton AW

更新日期：1988-01-01 00:00:00

abstract：:An understanding of corneal optics is important to optimize the visual outcome after eye surgery. Recent advances in the surgical techniques of lamellar keratoplasty have changed the strategies used for corneal transplantation. Lamellar keratoplasty has the advantage of having a lower rate of graft rejection, superior...

journal_title：Cornea

authors： Yamaguchi T,Satake Y,Dogru M,Ohnuma K,Negishi K,Shimazaki J

更新日期：2015-11-01 00:00:00

abstract：:The mechanism of ocular surface allergy in the forms of atopic conjunctivitis and vernal keratoconjunctivitis has been highlighted by specific functions of chemokines. In the context of late-phase allergic responses, these molecules have key roles in recruitment and activation of leukocytes. Their interaction with lig...

journal_title：Cornea

authors： Miyazaki D,Nakamura T,Komatsu N,Nawata N,Ikeda Y,Inoue Y,Higashi H,Ono SJ

更新日期：2004-11-01 00:00:00

abstract：PURPOSE:To compare corneal endothelial cell loss after cataract surgery by phacoemulsification and by Aqualase. METHODS:This was a prospective, randomized study of 75 eyes of 75 patients undergoing cataract surgery. Patients were randomly assigned to receive either phacoemulsification or Aqualase for cataract removal....

journal_title：Cornea

authors： Hu V,Hughes EH,Patel N,Whitefield LA

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:We standardized quality-controlled cord blood serum (CBS)-based eye drops and evaluated the efficacy of 1-month CBS treatment in the healing of diseased corneal epithelium in severe dry eye (DE) patients. METHODS:Seventeen graft-versus-host disease (GVHD) and 13 Sjogren syndrome patients with severe persistent...

journal_title：Cornea

authors： Versura P,Profazio V,Buzzi M,Stancari A,Arpinati M,Malavolta N,Campos EC

更新日期：2013-04-01 00:00:00