Dry Eye Assessment in Patients With Vitiligo.

Abstract:

PURPOSE:To evaluate tear osmolarity and tear film parameters in patients with vitiligo. METHODS:A total of 25 eyes of 25 patients with vitiligo with periocular involvement (group 1), 30 eyes of 30 patients with vitiligo without periocular involvement (group 2), and 20 eyes of 20 controls (group 3) were evaluated using the Ocular Surface Disease Index (OSDI) questionnaire, Schirmer I test, tear film breakup time, scoring of ocular surface fluorescein staining using a modified Oxford scale, and tear osmolarity. RESULTS:Mean tear osmolarity was 332 ± 16.3 mOsm/L in group 1, 308.8 ± 19.5 mOsm/L in group 2, and 286.3 ± 23.4 mOsm/L in group 3 (P < 0.001). There was no significant difference in Schirmer I test results among the 3 groups (16.5 ± 3.2 mm in group 1, 16.3 ± 4.7 mm in group 2, and 17.4 ± 4.2 mm in group 3) (P = 0.175). Tear film breakup time measurements in groups 1 (9.8 ± 3.5 seconds) and 2 (10.1 ± 4.3 seconds) were significantly lower than those in group 3 (18.5 ± 4.0 seconds) (P < 0.001). There was no significant difference among the 3 groups on the Oxford scale (0.04 ± 0.70 in group 1, 0.03 ± 0.33 in group 2, and 0.03 ± 0.20 in group 3) (P = 0.865). The mean Ocular Surface Disease Index score was significantly higher in groups 1 and 2 than in group 3 (42.1 ± 16.5 in group 1, 39.9 ± 17.3 in group 2, and 12.3 ± 11.6 in group 3) (P < 0.001). CONCLUSIONS:This study showed that vitiligo is associated with tear hyperosmolarity and tear film dysfunction. Patients with vitiligo with periocular involvement may be more prone to dry eye than those without ocular involvement.

journal_name

Cornea

journal_title

Cornea

authors

Erdur SK,Aydin R,Balevi A,Ozsutcu M,Kocabora MS

doi

10.1097/ICO.0000000000001469

subject

Has Abstract

pub_date

2018-04-01 00:00:00

pages

412-415

issue

4

eissn

0277-3740

issn

1536-4798

journal_volume

37

pub_type

杂志文章

相关文献

CORNEA文献大全
  • Two cases of anterior uveitis after laser eyebrow epilation.

    abstract:PURPOSE:Laser-assisted epilation of eyebrow hair has become a common practice, but a number of ocular complications can occur. We report the cases of 2 patients who had unilateral anterior uveitis after having undergone laser removal of eyebrow hair. METHODS:This report describes 2 patients who experienced eye pain, p...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000294

    authors: Gunes A,Yasar C,Tok L,Tok O

    更新日期:2015-01-01 00:00:00

  • Control of astigmatism aided by intraoperative keratometry.

    abstract::An evaluation of the final "sutures out" postoperative astigmatism in two groups of keratoconus patients undergoing penetrating keratoplasty is presented. Group I consists of a retrospective evaluation of keratoconus patients who underwent penetrating keratoplasty without using the Troutman Keratometer prior to suturi...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199309000-00005

    authors: Belmont SC,Troutman RC,Buzard KA

    更新日期:1993-09-01 00:00:00

  • Lamina Cribrosa Thickness in Patients With Keratoconus.

    abstract:PURPOSE:To evaluate the thickness and depth of lamina cribrosa (LC) in the optic nerve head region of the eyes in patients with nonglaucomatous keratoconus and to compare the thickness and depth with those of age-matched controls. METHODS:This was a cross-sectional, observational study comprising 45 patients with kera...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001379

    authors: Akkaya S,Küçük B

    更新日期:2017-12-01 00:00:00

  • Pentacam-based big bubble deep anterior lamellar keratoplasty in patients with keratoconus.

    abstract:PURPOSE:To describe the clinical results of Pentacam-based big bubble deep anterior lamellar keratoplasty (DALK) to achieve an intended 90% depth of initial lamellar trephination. METHODS:Fifty consecutive eyes of 50 patients with keratoconus, keratoglobus, and anterior stromal scars were included. DALK was performed ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31823f8c85

    authors: Riss S,Heindl LM,Bachmann BO,Kruse FE,Cursiefen C

    更新日期:2012-06-01 00:00:00

  • Descemet Membrane Endothelial Keratoplasty Patch for Persistent Corneal Hydrops.

    abstract:PURPOSE:To report successful management of a case of persistent keratoconus-related hydrops with a Descemet membrane endothelial keratoplasty (DMEK) patch graft. METHODS:A case of corneal hydrops persisting for 7 months treated with DMEK was identified. The following information was collected: demographic data, surgic...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001351

    authors: Tu EY

    更新日期:2017-12-01 00:00:00

  • The corneal-thickness profile in Hong Kong Chinese.

    abstract:PURPOSE:This study investigated the topographic corneal thickness in four groups of Hong Kong Chinese. METHODS:The corneal thickness was determined with an ultrasound pachometer mounted on a X-Y plate. A head rest was used to reduce further any movement from the subject during the measurement. After the central cornea...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199807000-00008

    authors: Lam AK,Douthwaite WA

    更新日期:1998-07-01 00:00:00

  • Visual Outcomes of Repeat Versus Primary Descemet Stripping Automated Endothelial Keratoplasty-A Paired Comparison.

    abstract:PURPOSE:To compare the results of repeat Descemet stripping automated endothelial keratoplasty (DSAEK) with those of primary DSAEK. MATERIALS AND METHODS:This retrospective study consisted of all consecutive eyes that underwent one or more repeat DSAEK surgeries after primary DSAEK performed at Villa Serena-Villa Igea...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000810

    authors: Nahum Y,Mimouni M,Madi S,Busin M

    更新日期:2016-05-01 00:00:00

  • Corneal laceration by sharp objects in children seven years of age and younger.

    abstract:PURPOSE:Young children are prone to develop amblyopia after penetrating injury. We sought to evaluate the management of penetrating corneal injury without intraocular foreign body (IOFB) in children

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3180301534

    authors: Segev F,Assia EI,Harizman N,Barequet I,Almer Z,Raz J,Moisseiev J

    更新日期:2007-04-01 00:00:00

  • Comparison of Tono-Pen AVIA intraocular pressure measurements performed at limbus with central corneal Tono-Pen AVIA intraocular pressure.

    abstract:PURPOSE:To compare Tono-Pen AVIA (TPA) intraocular pressure (IOP) measurements performed at the limbus with central corneal Tono-Pen AVIA (TPA) intraocular pressure. METHODS:Fifty-one patients attending our outpatient department with a best corrected visual acuity of ≥ 20/40, no corneal disease, and no astigmatism gre...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31827c9d25

    authors: Sharma R,Majumdar S,Sobti A,Arora T,Agarwal T,Dada T

    更新日期:2013-07-01 00:00:00

  • Development, Implementation, and Evaluation of Treatment Guidelines for Herpes Simplex Keratitis in Sydney, Australia.

    abstract:PURPOSE:To develop and measure the uptake of a local guideline for herpes simplex keratitis (HSK) and to standardize initial antiviral therapy in Australia. METHODS:The Registered Nurses' Association of Ontario Toolkit: "Implementation of Best Practice Guidelines" was used to develop, implement, and evaluate the guide...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002273

    authors: Cabrera-Aguas M,Kerdraon Y,Symes RJ,McCluskey P,Samarawickrama C,Rawlinson W,Watson SL

    更新日期:2020-07-01 00:00:00

  • Adenovirus epithelial keratitis.

    abstract::The authors sought to determine whether adenovirus could infect human corneal epithelium in vivo. They reviewed the medical records of six patients with adenovirus-positive viral corneal cultures who were examined at the Bascom Palmer Eye Institute between March 21, 1986, and December 31, 1992. The six patients with a...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Chodosh J,Miller D,Stroop WG,Pflugfelder SC

    更新日期:1995-03-01 00:00:00

  • Cyclosporine A Downregulates MMP-3 and MMP-13 Expression in Cultured Pterygium Fibroblasts.

    abstract:PURPOSE:To investigate the regulation of matrix metalloproteinase (MMP)-3 and MMP-13 expression over time and in the presence of cyclosporine A (CsA) in primary cultured human pterygium fibroblasts. We also examined the effects of CsA on cultured human pterygium fibroblasts. METHODS:Primary cultured human pterygium fi...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000477

    authors: Kim YH,Jung JC,Jung SY,Kim YI,Lee KW,Park YJ

    更新日期:2015-09-01 00:00:00

  • Corneal endothelial damage after trabeculectomy with mitomycin C in two patients with glaucoma with cornea guttata.

    abstract:PURPOSE:To report two patients with glaucoma who exhibited severe damage to the corneal endothelium after a trabeculectomy with mitomycin C (MMC). METHODS:This study includes clinical histories and specular microscopic pictures of the cases. RESULTS:Both patients were middle-aged women, underwent trabeculectomy with ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200204000-00012

    authors: Fukuchi T,Hayakawa Y,Hara H,Abe H

    更新日期:2002-04-01 00:00:00

  • A review of relative risks associated with four types of contact lenses.

    abstract::This paper reviews the data of Frank et al. in the light of increasing concern over the safety of contact lenses used for extended wear. Relative risks were calculated for four types of contact lenses (CLs): extended wear soft, daily wear soft, rigid gas-permeable (RGP), and polymethylmethacrylate (PMMA) lenses--worn ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199010001-00024

    authors: Bailey CS

    更新日期:1990-01-01 00:00:00

  • Invasive spindle cell carcinoma of the conjunctiva managed by full-thickness eye wall resection.

    abstract:PURPOSE:To describe an invasive spindle cell carcinoma of the conjunctiva managed by full-thickness eye wall resection. METHODS:A 51-year-old man developed a conjunctival mass that was excised and proved to be a spindle cell carcinoma. A tumor recurrence 20 months later was evaluated by ultrasound biomicroscopy (UBM) ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3180cfe80e

    authors: Shields JA,Eagle RC,Marr BP,Shields CL,Grossniklaus HE,Stulting RD

    更新日期:2007-09-01 00:00:00

  • Abnormal extracellular matrix in corneas with pseudophakic bullous keratopathy.

    abstract::The present study describes biochemical and morphological differences of pseudophakic bullous keratopathy (PBK) corneas as compared with normal corneas. At the ultrastructural level, all PBK corneas studied had abnormal fibrillar material posterior to the Descemet's membrane. In addition, two of the six PBK buttons ha...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Kenney MC,Chwa M

    更新日期:1990-04-01 00:00:00

  • Contralateral Autologous Corneal Transplantation Experience in Mexico City.

    abstract:PURPOSE:The aim of this study is to expand the limited knowledge regarding autologous contralateral penetrating keratoplasty. METHODS:We report the retrospective outcomes of patients who received autokeratoplasty and contralateral opaque corneas in the donor eye at a tertiary care ophthalmology hospital in Mexico City...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001020

    authors: Perez-Balbuena AL,Ancona-Lezama D,Delgado-Pelayo S,Martinez JD

    更新日期:2017-01-01 00:00:00

  • Clinical impact of conjunctivochalasis on the ocular surface.

    abstract:PURPOSE:To report the clinical impact of conjunctivochalasis on the ocular surface by evaluating the effect of a new concept of conjunctivochalasis operation on the resolution of patients' symptoms and corneal epithelial damage. Also, the association of inflammation with conjunctivochalasis is examined. PATIENTS AND M...

    journal_title:Cornea

    pub_type: 临床试验,杂志文章

    doi:10.1097/01.ico.0000178740.14212.1a

    authors: Yokoi N,Komuro A,Nishii M,Inagaki K,Tanioka H,Kawasaki S,Kinoshita S

    更新日期:2005-11-01 00:00:00

  • Temperature variations in eyebank containers: comparative study of corneal transport containers and packing methods.

    abstract::Two containers ("Iowa" and "Virginia") commonly used for transporting donor corneas, and various packing methods were evaluated for constancy of temperature maintenance. The larger Iowa container was found to be superior for extended storage. Packing methods that allowed the vials (containing McCarey-Kaufman medium) t...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: York KK,Ward DE,Smith RE

    更新日期:1985-01-01 00:00:00

  • Some factors influencing outcome after keratoprosthesis surgery.

    abstract::Eleven patients with severe corneal disease have been operated with a collar-button-shaped keratoprosthesis and have been followed for 9-36 months. Two of the devices have been removed, but the remainder are securely in place. Six of the patients have benefitted substantially in terms of improved vision. The complicat...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199405000-00004

    authors: Dohlman CH,Doane MG

    更新日期:1994-05-01 00:00:00

  • Trends in the etiology of infectious corneal ulcers at the F. I. Proctor Foundation.

    abstract:OBJECTIVE:We analyzed laboratory results from corneal ulcers seen from 1976 to 1999 at the Francis I. Proctor Foundation, a referral center in San Francisco, to determine the relative frequencies of pathogens and to analyze for trends in frequencies of the most common pathogens. The results were compared with a previou...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200405000-00009

    authors: Varaprasathan G,Miller K,Lietman T,Whitcher JP,Cevallos V,Okumoto M,Margolis TP,Yinghui M,Cunningham ET Jr

    更新日期:2004-05-01 00:00:00

  • Enhancing DMEK Success by Identifying Optimal Levels of Trypan Blue Dye Application to Donor Corneal Tissue.

    abstract:PURPOSE:The purpose of this study was to determine the correct concentration and duration of application of trypan blue dye to Descemet membrane endothelial keratoplasty (DMEK) donor corneal tissue before transplant to enhance visibility while minimizing damage to the tissue. METHODS:Corneas were precut for DMEK using...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001074

    authors: Majmudar PA,Johnson L

    更新日期:2017-02-01 00:00:00

  • Evaluation of the Safety and Efficacy of a Low-Temperature Plasma Surgical System for Pterygium.

    abstract:PURPOSE:Surgical excision is the standard treatment for pterygium. This study was conducted to evaluate the safety and efficacy of a novel technique using low-temperature plasma (LTP) for excision and hemostasis in pterygium surgery. METHODS:A prospective, comparative, and randomized clinical trial was conducted on 60...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002487

    authors: Huang H,Li S,Zhong J,Wang B,Peng L,Deng Y,Wang M,Yuan J

    更新日期:2020-12-01 00:00:00

  • Conjunctival malignant melanoma-associated pseudomelanoma of the apposing tarsal conjunctiva.

    abstract:PURPOSE:To describe a case of conjunctival malignant melanoma associated with pseudomelanomatous alteration of the apposing tarsal conjunctiva. METHODS:A 93-year-old woman presented with an elevated, pigmented mass on her superior bulbar conjunctiva. The tumor was associated with increased pigmentation of the apposing...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000226358.26678.98

    authors: Reddy S,Finger PT,Kurli M,Bui A,Iacob CE

    更新日期:2006-10-01 00:00:00

  • Efficacy of Corneal Collagen Cross-Linking for the Treatment of Keratoconus: A Systematic Review and Meta-Analysis.

    abstract:PURPOSE:To examine the efficacy of corneal collagen cross-linking (CXL) for the treatment of keratoconus (KCN). METHODS:A systemic literature review and meta-analysis of ocular functional and structural parameters of patients with KCN undergoing cross-linking procedures were performed using PubMed and the web of scien...

    journal_title:Cornea

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/ICO.0000000000000723

    authors: Meiri Z,Keren S,Rosenblatt A,Sarig T,Shenhav L,Varssano D

    更新日期:2016-03-01 00:00:00

  • Robotically Assisted Pterygium Surgery: First Human Case.

    abstract:PURPOSE:Little research has been done on robotic ocular microsurgery. This study aims to demonstrate the feasibility of pterygium surgery using a robotic surgical system. METHODS:Robot-assisted pterygium surgery was performed on a 73-year-old patient with nasal and temporal pterygia using the DaVinci Si HD robotic Sur...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000561

    authors: Bourcier T,Chammas J,Becmeur PH,Danan J,Sauer A,Gaucher D,Liverneaux P,Mutter D

    更新日期:2015-10-01 00:00:00

  • Surgical monovision and monovision reversal in LASIK.

    abstract:PURPOSE:This study was designed to assess the success of surgical monovision in presbyopic patients. METHODS:A university refractive surgery center retrospective chart review of 82 patients who elected to undergo surgical monovision with laser in situ keratomileusis (LASIK) between January 2000 and January 2003 was co...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000178722.19317.7b

    authors: Reilly CD,Lee WB,Alvarenga L,Caspar J,Garcia-Ferrer F,Mannis MJ

    更新日期:2006-02-01 00:00:00

  • High-Resolution Optical Coherence Tomography Findings of Lisch Epithelial Corneal Dystrophy.

    abstract:PURPOSE:To describe a case of Lisch epithelial corneal dystrophy (LECD) and present its unique characteristics on high-resolution optical coherence tomography (HR-OCT). METHODS:A 78-year-old man with whorled corneal epithelial opacities in the right eye was referred for the evaluation of ocular surface squamous neopla...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000722

    authors: Pole C,Sise A,Joag M,Galor A,Bermudez-Magner JA,Dubovy S,Karp CL

    更新日期:2016-03-01 00:00:00

  • Epidermal growth factor and corneal wound healing. A multicenter study.

    abstract::A randomized, double-blind, placebo-controlled, multicenter clinical trial was conducted in five centers to assess safety, ocular tolerance, and efficacy of an ophthalmic solution of epidermal growth factor (EGF) for the treatment of traumatic corneal epithelial defects. One hundred four patients completed the study: ...

    journal_title:Cornea

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/00003226-199207000-00007

    authors: Pastor JC,Calonge M

    更新日期:1992-07-01 00:00:00

  • Effects of basic FGF and TGF beta 1 on F-actin and ZO-1 organization during cat endothelial wound healing.

    abstract::Previous studies suggest the existence of two separate and distinct mechanisms of endothelial wound healing (i.e., cell migration and cell spreading), which may be controlled by unique, injury-dependent, wound-related factors. The purpose of our study was to evaluate potential biologic mediators regulating healing of ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Petroll WM,Jester JV,Barry-Lane PA,Cavanagh HD

    更新日期:1996-09-01 00:00:00