Evaluation of the Safety and Efficacy of a Low-Temperature Plasma Surgical System for Pterygium.

Abstract:

PURPOSE:Surgical excision is the standard treatment for pterygium. This study was conducted to evaluate the safety and efficacy of a novel technique using low-temperature plasma (LTP) for excision and hemostasis in pterygium surgery. METHODS:A prospective, comparative, and randomized clinical trial was conducted on 60 patients (60 eyes) undergoing pterygium excision with conjunctival autografts using fibrin glue. Patients were equally divided into the following 2 groups: a control group and a LTP group. Postoperative follow-up visits were scheduled on day 1, week 1, and months 1 and 3, and recurrence was evaluated at 1 year. Patients were examined for operative time, best corrected visual acuity, conjunctival autograft inflammation (CAI), graft stability (GS), pain, recurrence, and final appearance. Factors related to pterygium recurrence and final appearance were analyzed. RESULTS:Mean operative times were shorter in the LTP group (16.7 ± 3.4 min) than those in the control group (20.1 ± 4.7 min, P = 0.002). LTP eyes had milder CAI than control eyes at postoperative day 1 (P = 0.000) and week 1 (P = 0.000). Patients in the LTP group exhibited better GS (P = 0.01) and milder pain (P = 0.04) than those in the control group on day 1. Two control patients (6.7%) and no (0%) LTP patients experienced recurrence (P = 0.08). GS and CAI were the significant factors contributing to recurrence (GS: R = 0.425, P = 0.001; CAI: R = 0.309, P = 0.016). CONCLUSIONS:LTP to replace surgical blades and disposable cautery for ablation and hemostasis is safe and efficient for pterygium surgery, resulting in shorter operative time, milder inflammation, and better graft stability without increasing complication risk.

journal_name

Cornea

journal_title

Cornea

authors

Huang H,Li S,Zhong J,Wang B,Peng L,Deng Y,Wang M,Yuan J

doi

10.1097/ICO.0000000000002487

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

1581-1587

issue

12

eissn

0277-3740

issn

1536-4798

pii

00003226-202012000-00019

journal_volume

39

pub_type

杂志文章

相关文献

CORNEA文献大全
  • The change in ocular higher-order aberrations after pterygium excision with conjunctival autograft: a 1-year prospective clinical trial.

    abstract:PURPOSE:To investigate the effects of pterygium excision with conjunctival autograft plus corneal polishing on ocular higher-order aberrations (HOAs) and to monitor the changes throughout the first postoperative year. METHODS:A total of 18 eyes of 16 patients with primary pterygium who had an indication for surgical e...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3182431465

    authors: Gumus K,Topaktas D,Göktaş A,Karakucuk S,Oner A,Mirza GE

    更新日期:2012-12-01 00:00:00

  • Efficacy of Corneal Collagen Cross-Linking for the Treatment of Keratoconus: A Systematic Review and Meta-Analysis.

    abstract:PURPOSE:To examine the efficacy of corneal collagen cross-linking (CXL) for the treatment of keratoconus (KCN). METHODS:A systemic literature review and meta-analysis of ocular functional and structural parameters of patients with KCN undergoing cross-linking procedures were performed using PubMed and the web of scien...

    journal_title:Cornea

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/ICO.0000000000000723

    authors: Meiri Z,Keren S,Rosenblatt A,Sarig T,Shenhav L,Varssano D

    更新日期:2016-03-01 00:00:00

  • Safety profile of bevacizumab on cultured human corneal cells.

    abstract:PURPOSE:To study the corneal biocompatibility of bevacizumab on various cultured human corneal cells. METHODS:Cell cultures of corneal keratinocytes (CKs), corneal fibroblasts (CFs), and corneal endothelial cells (CECs) were harvested from human donor eyes and exposed to various concentrations of bevacizumab (0.25-5.0...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3180de1d0a

    authors: Yoeruek E,Spitzer MS,Tatar O,Aisenbrey S,Bartz-Schmidt KU,Szurman P

    更新日期:2007-09-01 00:00:00

  • Pachymetry-guided intrastromal air injection ("pachy-bubble") for deep anterior lamellar keratoplasty.

    abstract::To evaluate an innovative technique for intrastromal air injection to achieve deep anterior lamellar keratoplasty (DALK) with bare Descemet membrane (DM). Thirty-four eyes with anterior corneal pathology, including 27 with keratoconus, underwent DALK. After 400 μm trephination with a suction trephine, ultrasound pachy...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31823f8f2d

    authors: Ghanem RC,Ghanem MA

    更新日期:2012-09-01 00:00:00

  • Inhibition of human corneal epithelium with immunotoxin 454A12-rRA.

    abstract::We examined the effects of the immunotoxin 454A12-rRa on proliferating and confluent human corneal epithelium (HCE) in vitro. Proliferating HCE was sensitive to 454A12-rRA in a dose-dependent fashion. At immunotoxin concentrations of 1,000 ng/ml for 7 days we observed an 86% reduction in cell counts. Confluent HCE was...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199209000-00010

    authors: Fulcher SF,Foulks GN,Wilkerson M,Cobo LM,Jaffe GJ,Hatchell DL

    更新日期:1992-09-01 00:00:00

  • Growth and survival of Fusarium solani-F. oxysporum complex on stressed multipurpose contact lens care solution films on plastic surfaces in situ and in vitro.

    abstract:PURPOSE:To analyze factors implicating the association of ReNu with MoistureLoc (ReNu ML) multipurpose contact lens solution (MPS) with the increased incidence of Fusarium keratitis. METHODS:Used contact lens cases with and without contact lenses and MPS containers were collected from patients with confirmed or possib...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31802dd3a4

    authors: Zhang S,Ahearn DG,Noble-Wang JA,Stulting RD,Schwam BL,Simmons RB,Pierce GE,Crow SA Jr

    更新日期:2006-12-01 00:00:00

  • Femtosecond laser-assisted inverted mushroom keratoplasty.

    abstract:PURPOSE:To evaluate best-corrected visual acuity (BCVA), refractive outcome, corneal topography, optical coherence tomography, and endothelial cell density 12 months after femtosecond laser-assisted inverted mushroom keratoplasty. METHODS:We performed a prospective study of a surgical case series of 5 patients undergo...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/QAI.0b013e31815bad0c

    authors: Cheng YY,Tahzib NG,van Rij G,van Cleynenbreugel H,Pels E,Hendrikse F,Nuijts R

    更新日期:2008-07-01 00:00:00

  • Clinical Profile of Bilateral Microsporidial Keratoconjunctivitis in Healthy Individuals-A Case Series With Long-term Follow-up.

    abstract:PURPOSE:To describe bilateral microsporidial keratoconjunctivitis in healthy individuals with long-term follow-up. METHODS:Six cases of smear-positive bilateral microsporidial keratoconjunctivitis were diagnosed and followed up during the study period August 2017 to January 2019. Associated risk factors, clinical feat...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002297

    authors: Mohanty A,Mitra S,Das S,Priyadarshini S,Sahu SK

    更新日期:2020-07-01 00:00:00

  • Deep anterior lamellar keratoplasty using the manual dissection technique of Melles: a histopathologic correlation.

    abstract:PURPOSE:To report the histopathologic findings in the host tissue of 2 human keratoconic corneas undergoing maximum-depth anterior lamellar keratoplasty (MDALK) using the manual dissection technique described by Melles. METHODS:Corneal buttons were examined from 2 patients with keratoconus who underwent MDALK using th...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000179930.97651.8f

    authors: Saw VP,Ng T,Crouch R,Maloof AJ

    更新日期:2006-09-01 00:00:00

  • Conjunctival involvement in chronic recurrent multifocal osteomyelitis.

    abstract:PURPOSE:To report a case of chronic recurrent multifocal osteomyelitis (CRMO) with conjunctival involvement. METHODS:Retrospective chart review. RESULTS:A 10-year-old girl who complained of fatigue and debilitating pain in both hips and legs for >1 year had recurrent episodes of redness and discharge in both eyes wit...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181589309

    authors: Ozbek Z,Makay B,Unsal E,Durak I,Gunes D,Anal O,Ozer E

    更新日期:2008-01-01 00:00:00

  • Post-traumatic fungal keratitis caused by Carpoligna sp.

    abstract:PURPOSE:To report the first case of fungal keratitis caused by presumed Carpoligna species. METHODS:A 37-year-old gardener sustained a full-thickness, stellate corneal laceration while cutting wood outdoors with a circular saw. Two months after surgical repair, he developed a severe infectious keratitis with descemeto...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181af3954

    authors: Chew HF,Jungkind DL,Mah DY,Raber IM,Toll AD,Tokarczyk MJ,Cohen EJ

    更新日期:2010-04-01 00:00:00

  • Adjustment of Intrastromal Corneal Ring Segments After Unsuccessful Implantation in Keratoconic Eyes.

    abstract:PURPOSE:To evaluate visual, refractive, and corneal topography outcomes in eyes with keratoconus that have undergone exchange/adjustment surgery with a new intrastromal corneal ring segment (ICRS) combination after unsuccessful visual and/or refractive outcomes after primary ICRS surgery. METHODS:A retrospective nonra...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001449

    authors: Monteiro T,Mendes JF,Faria-Correia F,Franqueira N,Madrid-Costa D,Alfonso JF

    更新日期:2018-02-01 00:00:00

  • Limbal stem cell transplantation for the treatment of subepithelial amyloidosis of the cornea (gelatinous drop-like dystrophy).

    abstract:PURPOSE:Subepithelial amyloidosis of the cornea, or gelatinous drop-like corneal dystrophy (GDD), is a severe form of corneal stromal amyloidosis predominantly found in the Japanese population. GDD causes severe visual disturbances with irritating symptoms, and keratoplasty is inevitably complicated by early recurrence...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200203000-00010

    authors: Shimazaki J,Shimmura S,Tsubota K

    更新日期:2002-03-01 00:00:00

  • Gene transfer using micellar nanovectors inhibits corneal neovascularization in vivo.

    abstract:PURPOSE:The efficacy of gene therapy using nonviral vector based on polyplex micelle has been studied against corneal neovascularization in mice. METHODS:A block copolymer, poly(ethylene glycol) (PEG)-block-polycation carrying ethylenediamine units in the side chain (PEG-b-P[Asp(DET)]), was prepared. PEG-b-P[Asp(DET)]...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318206c893

    authors: Iriyama A,Usui T,Yanagi Y,Amano S,Oba M,Miyata K,Nishiyama N,Kataoka K

    更新日期:2011-12-01 00:00:00

  • Aqueous tear production in patients with neurotrophic keratitis.

    abstract::The purpose of this study was to determine whether corneal epithelial defects and epitheliopathy in patients with unilateral dysfunction of the ophthalmic division of the trigeminal nerve (neurotrophic keratitis) is associated with reduced aqueous tear production. Sensation of the skin, cornea, and nasal mucosa, aqueo...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199603000-00005

    authors: Heigle TJ,Pflugfelder SC

    更新日期:1996-03-01 00:00:00

  • A case of infectious crystalline keratopathy occurring long after penetrating keratoplasty.

    abstract:PURPOSE:To report a 64-year-old woman's case of infectious crystalline keratopathy (ICK) that occurred 9 years after the penetrating keratoplasty (PKP). METHODS:This study includes clinical history and histopathologic findings of the case. RESULTS:As historic background, the patient underwent PKP for lattice dystroph...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199801000-00018

    authors: Matsumoto A,Sano Y,Nishida K,Yokoi N,Hara J,Kinoshita S

    更新日期:1998-01-01 00:00:00

  • Effect of topical cyclosporin A on herpetic stromal keratitis in a mouse model.

    abstract:PURPOSE:To study the effect of topical cyclosporin A on herpetic stromal keratitis (HSK) in a mouse model. METHODS:The corneas of BALB/c mice were infected with herpes simplex type 1 virus. The mice were divided into 4 groups according to topical treatment methods: vehicle solution, 0.01% cyclosporin A, 0.1% cyclospor...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318160602d

    authors: Yoon KC,Heo H,Kang IS,Lee MC,Kim KK,Park SH,Cho KO

    更新日期:2008-05-01 00:00:00

  • Corneal Stiffening by a Bacteriochlorophyll Derivative With Dextran and Near-Infrared Light: Effect of Shortening Irradiation Time up to 1 Minute.

    abstract:PURPOSE:The aim of this study is to determine the effect of variation of the exposure time of near-infrared irradiation on corneal stiffening after a bacteriochlorophyll derivative (WST11) with dextran (WST-D) application. METHODS:One hundred four paired eyes of 3-month-old New Zealand White rabbits were included in t...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001272

    authors: Brekelmans J,Goz A,Dickman MM,Brandis A,Sui X,Wagner HD,Nuijts RMMA,Scherz A,Marcovich AL

    更新日期:2017-11-01 00:00:00

  • Ocular morbidity associated with airbag deployment: a report of seven cases and a review of the literature.

    abstract:PURPOSE:To review ocular injuries secondary to airbag deployment that were seen in our institution and were reported in the literature. METHODS:Patients examined at our institution between 1997 and 2000 were evaluated for ocular injuries caused by airbags. A review of the medical literature using Medline was performed...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/00003226-200103000-00009

    authors: Ball DC,Bouchard CS

    更新日期:2001-03-01 00:00:00

  • Survival after transplantation of corneas from a rabies-infected donor.

    abstract:PURPOSE:To examine the tissue samples of 2 corneal recipients from a rabies-infected donor for the presence of rabies to explain their survival. METHODS:Interventional case series with a review of the literature. The explanted corneal donor buttons were examined via nested reverse transcriptase polymerase chain reacti...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/ICO.0b013e3181e4572a

    authors: Vetter JM,Frisch L,Drosten C,Ross RS,Roggendorf M,Wolters B,Müller T,Dick HB,Pfeiffer N

    更新日期:2011-02-01 00:00:00

  • Impression cytology study of conjunctival epithelial phenotypes on the healing ocular surface after pterygium excision.

    abstract:PURPOSE:To compare the process of conjunctival epithelial regeneration after three types of pterygium excision procedures. METHODS:Thirty-eight patients (45 eyes) with primary pterygium were randomly assigned to a bare-sclera procedure (group 1, 15 eyes of 12 patients), bare-sclera with intraoperative mitomycin C (MMC...

    journal_title:Cornea

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00003226-200104000-00002

    authors: Tseng SH,Chen YT,Cheng HC,Huang FC,Lee SC,Chen FK

    更新日期:2001-04-01 00:00:00

  • The intraoperative use of mitomycin-C in excision of ocular surface neoplasia with or without limbal autograft transplantation.

    abstract:PURPOSE:To evaluate the efficacy of intraoperative mitomycin-C in excision of ocular surface neoplasia for prevention of recurrence. METHODS:Seven patients (eight eyes), three men and four women, aged 56 to 87 years (mean, 73.8 years), with lesions suspicious for corneal or conjunctival neoplasia, were operated on bet...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200201000-00004

    authors: Siganos CS,Kozobolis VP,Christodoulakis EV

    更新日期:2002-01-01 00:00:00

  • Moderately Long-Term Safety and Efficacy of Repeat Penetrating Keratoplasty.

    abstract:PURPOSE:To investigate the moderately long-term safety and efficacy of repeat penetrating keratoplasty (PK) for treatment of a failed PK graft. METHODS:Retrospective consecutive clinical case series. Of 992 consecutive cases that underwent PK at Baptist Eye Institute, Kyoto, Japan, between April 1998 and September 201...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001694

    authors: Kitazawa K,Wakimasu K,Kayukawa K,Yokota I,Inatomi T,Hieda O,Sotozono C,Kinoshita S

    更新日期:2018-10-01 00:00:00

  • Anterior-Segment Optical Coherence Tomography and Scanning Electron Microscopy to Evaluate Corneal Epithelial Changes in Patients Undergoing Glaucoma Therapy.

    abstract:PURPOSE:To measure corneal epithelial thickness (CET) in patients with glaucoma using anterior-segment optical coherence tomography and to evaluate CET changes in relation to corneal epithelial microvilli analyzed by scanning electron microscopy (SEM). METHODS:Twenty-two eyes (16 patients) being treated with preservat...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001752

    authors: Cennamo G,Montorio D,Del Prete S,Del Prete A,Cennamo G

    更新日期:2018-12-01 00:00:00

  • In Vivo Confocal Microscopy Findings in Bowman Layer Transplantation.

    abstract:PURPOSE:To report the in vivo confocal microscopy (IVCM) findings of a case who underwent femtosecond laser-assisted Bowman layer transplantation (BLT). METHODS:This is a case report. RESULTS:In a 25-year-old man with previous diagnosis of keratoconus in whom a BLT was performed using the femtosecond laser-assisted t...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002561

    authors: García de Oteyza G,Vazquez-Romo KA,Hernández-Quintela E,de Wit Carter G,García-Albisua AM

    更新日期:2020-10-19 00:00:00

  • Histopathologic findings in explanted osteo-odontokeratoprosthesis.

    abstract:PURPOSE:To report the histologic findings in three explanted osteo-odontokeratoprosthesis (OOKP) laminae. METHODS:The osteodental lamina of patient 1 with linear IgA bullous dermatosis had to be explanted 15 months after OOKP surgery because of permanent leakage after the resorption of the inferior half of the bone/de...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200205000-00013

    authors: Stoiber J,Csáky D,Schedle A,Ruckhofer J,Grabner G

    更新日期:2002-05-01 00:00:00

  • Corneal steepening after epikeratoplasty.

    abstract::Four patients had removal of their epikeratoplasty lenticules for unsatisfactory visual results. This was out of a consecutive series of 36 eyes. Three eyes were myopic and one was aphakic. In all four eyes, there was significant corneal steepening with an average increase in myopia of 2.4 diopters and an average incr...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Nirankari VS

    更新日期:1989-12-01 00:00:00

  • Limbal Stem Cell Deficiency After Glaucoma Surgery.

    abstract:PURPOSE:To characterize the clinical presentation of limbal stem cell deficiency (LSCD) associated with glaucoma surgeries. METHODS:This is a retrospective cross-sectional study of patients with LSCD and glaucoma who presented to the Stein Eye Institute at the University of California, Los Angeles, between 2009 and 20...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002249

    authors: Sun Y,Yung M,Huang L,Tseng C,Deng SX

    更新日期:2020-05-01 00:00:00

  • Corneal Cross-Linking With Verteporfin and Nonthermal Laser Therapy.

    abstract:PURPOSE:To test whether verteporfin with a nonthermal laser increases corneal mechanical stiffness and resistance to enzymatic degradation ex vivo. METHODS:Thirty human corneas (n = 5 per group) were treated with verteporfin alone (V), irradiated with nonthermal laser therapy (689 nm) alone (NTL), or received combined...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001473

    authors: Alageel SA,Arafat SN,Salvador-Culla B,Kolovou PE,Jahanseir K,Kozak A,Braithwaite GJC,Ciolino JB

    更新日期:2018-03-01 00:00:00

  • Combination topical therapy for conjunctival primary acquired melanosis with atypia and periocular lentigo maligna.

    abstract:PURPOSE:To report the case of a patient who initially presented with primary acquired melanosis (PAM) without atypia of the conjunctiva and later developed lentigo maligna of the eyelids and PAM with atypia of the conjunctiva. We illustrate the utility of combination topical therapy with adjunctive cryotherapy to treat...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000277

    authors: Bratton EM,Knutsen-Larson S,Durairaj VD,Gregory DG,Mellette JR

    更新日期:2015-01-01 00:00:00