Cyclosporine A Downregulates MMP-3 and MMP-13 Expression in Cultured Pterygium Fibroblasts.

abstract：PURPOSE:To describe a surgical technique to achieve the desired plane during deep anterior lamellar keratoplasty (DALK) in eyes with Descemet membrane (DM) tears due to previous hydrops. METHODS:This was a prospective, consecutive, interventional case series of DALK in 12 keratoconic eyes with healed hydrops. Dissecti...

journal_title：Cornea

authors： Goweida MB,Sobhy M,Seifelnasr M,Liu C

更新日期：2019-04-01 00:00:00

abstract：PURPOSE:Ocular injuries after exposure to the vesicant sulfur mustard (SM) are characterized by acute corneal erosions and inflammation of the anterior segment that may be followed by delayed limbal stem cell deficiency (LSCD), expressed clinically by corneal neovascularization and epithelial defects. The present study...

journal_title：Cornea

authors： Kadar T,Dachir S,Cohen M,Gutman H,Cohen L,Brandeis R,Horwitz V,Amir A

更新日期：2013-04-01 00:00:00

abstract：:To determine the diagnostic usefulness of routine staining of corneal buttons with alcian blue, we evaluated 150 consecutive corneal specimens with hematoxylin and eosin and alcian blue stains. Overall, 67% of specimens demonstrated deposition of acid mucopolysaccharide. More specifically, positive alcian blue stainin...

journal_title：Cornea

authors： Weiss JS,Orlando F,Albert DM

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:To determine the proportion of patients who were dispensed amantadine and diagnosed with corneal edema or Fuchs dystrophy within specified time frames. METHODS:Postmarketing surveillance study. The national Veterans Health Administration pharmacy and clinical databases were used to identify a cohort of veteran...

journal_title：Cornea

authors： French DD,Margo CE

更新日期：2007-10-01 00:00:00

abstract：:We present two cases of posterior amorphous corneal dystrophy in members of the same family. We correlated the clinical findings with refraction, topography, and ultrasound biomicroscopy (UBM). This is the first report of UBM findings in amorphous corneal dystrophy and we describe the depth of stromal opacification me...

journal_title：Cornea

authors： Castelo Branco B,Chalita MR,Casanova FH,Castelo Branco AB,Allemann N,de Freitas D

更新日期：2002-03-01 00:00:00

abstract：PURPOSE:To evaluate the effect of obstructive sleep apnea-hypopnea syndrome (OSAHS) on the meibomian glands, ocular surface, and tear parameters. METHODS:The study included 59 individuals (32 subjects with OSAHS, 27 control subjects) who underwent polysomnography in the Chest Diseases Clinic. The right eyes of all ind...

journal_title：Cornea

authors： Muhafiz E,Ölçen M,Erten R,Bozkurt E

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:To determine the factors associated with clinically significant dry eye after keratorefractive surgery. METHODS:This is a large database retrospective study that included consecutive cases of myopic laser in situ keratomileusis (LASIK) or photorefractive keratectomy performed between 2008 and 2016 at Care-Visi...

journal_title：Cornea

authors： Shehadeh-Mashor R,Mimouni M,Shapira Y,Sela T,Munzer G,Kaiserman I

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:To present a novel apparatus for simulating the anterior and posterior segment pressure dynamics involved in executing Descemet membrane endothelial keratoplasty (DMEK) surgery when using a chamber-shallowing technique. METHODS:An artificial anterior chamber (AAC), 18-mm trephine, latex glove, two 3-mL syringe...

journal_title：Cornea

authors： Sáles CS,Straiko MD,Fernandez AA,Odell K,Dye PK,Tran KD

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:To describe the technique and outcomes of limbal stem cell-sparing lamellar keratoplasty (LSCS-LKP) for the management of advanced keratoglobus (KGB). METHODS:In a sequential interventional case series from March 2010 to December 2012, 8 eyes of 6 patients with advanced KGB underwent an LSCS-LKP. Three patient...

journal_title：Cornea

authors： Karimian F,Baradaran-Rafii A,Faramarzi A,Akbari M

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:We report a patient with chronic Sweet syndrome (SS) treated by anti-Tumor Necrosis Factor (TNF) therapy, who presented with a severe bilateral chemosis. METHODS:Case report. RESULTS:Conjunctival biopsy revealed an ocular localization of SS. CONCLUSIONS:SS is a rare disorder that usually affects middle-age w...

journal_title：Cornea

authors： Michel G,Lhermitte B,Cribier B,Speeg-Schatz C,Bourcier T

更新日期：2008-12-01 00:00:00

abstract：:Fourteen patients presenting with neuropsychiatric manifestations of Wilson's disease were treated with oral tetrathiomolybdate (TM) for 8 weeks followed by oral zinc (Zn) maintenance therapy. The patients were evaluated prospectively at baseline and at yearly intervals for up to 5 years by slit-lamp biomicroscopy and...

journal_title：Cornea

authors： Esmaeli B,Burnstine MA,Martonyi CL,Sugar A,Johnson V,Brewer GJ

更新日期：1996-11-01 00:00:00

abstract：PURPOSE:To describe a case of transient band-like keratopathy after ocular exposure to fluocinonide cream and ketoconazole shampoo. DESIGN:Observational case report. RESULTS:A 40-year-old patient presented with acute pain, photophobia, lacrimation, and redness in 1 eye. The symptoms began while using fluocinonide cre...

journal_title：Cornea

authors： Savage HI,Edgington B,Appel J

更新日期：2005-04-01 00:00:00

abstract：PURPOSE:To report on the safety and clinical use of combined subconjunctival and intracorneal bevacizumab for corneal neovascularization. METHODS:The charts of 12 consecutive patients with corneal neovascularization who received combined subconjunctival and intracorneal injections of bevacizumab (2.5 mg/0.1 mL) were r...

journal_title：Cornea

authors： Yeung SN,Lichtinger A,Kim P,Amiran MD,Slomovic AR

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:Corneal lesions such as ulcers and erosions are major complications observed in patients with severe ocular allergic diseases. We aimed to look into the relationship between specific clinical conjunctival findings and the severity of corneal complications. METHODS:Thirty eyes of 6 patients with vernal kerato...

journal_title：Cornea

authors： Tanaka M,Dogru M,Takano Y,Miyake-Kashima M,Asano-Kato N,Fukagawa K,Tsubota K,Fujishima H

更新日期：2004-07-01 00:00:00

abstract：PURPOSE:To assess the use of serial computed tomography (CT) in the detection of osteo-odonto-lamina resorption in osteo-odonto-keratoprosthesis (OOKP) and to investigate the use of new volumetric software, Advanced Lung Analysis software (3D-ALA; GE Healthcare), for detecting changes in OOKP laminar volume. METHODS:A...

journal_title：Cornea

authors： Sipkova Z,Lam FC,Francis I,Herold J,Liu C

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:To report a case of conjunctival proliferation in a 2.5-year-old boy after initial evidence of a mild chemical injury after ocular exposure to pepper spray (oleoresin capsicum). METHODS:Case report with ophthalmologic and histologic findings. RESULTS:A child presented with mild conjunctival injection and chem...

journal_title：Cornea

authors： Gerber S,Frueh BE,Tappeiner C

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:To report the in vivo confocal microscopy (IVCM) findings of a case who underwent femtosecond laser-assisted Bowman layer transplantation (BLT). METHODS:This is a case report. RESULTS:In a 25-year-old man with previous diagnosis of keratoconus in whom a BLT was performed using the femtosecond laser-assisted t...

journal_title：Cornea

authors： García de Oteyza G,Vazquez-Romo KA,Hernández-Quintela E,de Wit Carter G,García-Albisua AM

更新日期：2020-10-19 00:00:00

abstract：PURPOSE:Endogenous hyaluronan (HA) has previously been shown to be a part of corneal wound healing after photorefractive keratectomy (PRK). HA is known to bind considerable amounts of water. This study aimed to show whether HA colocalized with water in the wound area after PRK. METHODS:Five New Zealand White rabbits w...

journal_title：Cornea

authors： Weber BA,Fagerholm P,Johansson B

更新日期：1997-09-01 00:00:00

abstract：PURPOSE:Intrastromal corneal ring segments (ICRSs) are small arc-like implants that are being used increasingly as a minimally invasive treatment for patients with keratoconus. This study assessed the effectiveness of KeraRing implants, a type of ICRS, to treat keratoconus. METHODS:Retrospective case series descriptiv...

journal_title：Cornea

authors： Gharaibeh AM,Muhsen SM,AbuKhader IB,Ababneh OH,Abu-Ameerh MA,Albdour MD

更新日期：2012-02-01 00:00:00

abstract：PURPOSE:To evaluate the prevalence of different topographic patterns in refractive surgery candidates and to estimate the extent of candidate rejection based on topography alone. METHODS:We performed a retrospective evaluation of videokeratographies of previously unoperated refractive surgery candidates. The defined t...

journal_title：Cornea

authors： Varssano D,Kaiserman I,Hazarbassanov R

更新日期：2004-08-01 00:00:00

abstract：PURPOSE:To report the association between colonization of contact lenses with Streptococcus pneumoniae and the observation of corneal infiltrative events in a group of patients wearing disposable hydrogel lenses on an extended-wear schedule. METHODS:In a prospective clinical trial, 330 patients wore disposable hydroge...

journal_title：Cornea

authors： Sankaridurg PR,Sharma S,Willcox M,Sweeney DF,Naduvilath TJ,Holden BA,Rao GN

更新日期：1999-05-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the antiangiogenic activity of AU6, a novel 6-amino acid peptide derived from Kringle V of human apolipoprotein (a). METHODS:RF/6A rhesus macaque choroid endothelial cells were used for in vitro studies. MTS [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sul...

journal_title：Cornea

authors： Wang Z,Zhao H,Ma JX,Xu X

更新日期：2014-04-01 00:00:00

abstract：PURPOSE:To evaluate outcomes of endothelial keratoplasty (EK) without Descemet membrane stripping for treatment of failed penetrating keratoplasty (PKP). METHODS:Retrospective cohort study of all eyes that underwent EK without Descemet membrane stripping for failed PKP at one institution between May 2008 and June 2010...

journal_title：Cornea

authors： Heitor de Paula F,Kamyar R,Shtein RM,Sugar A,Mian SI

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:We characterized the presence of hemangiogenesis (HA) and lymphangiogenesis (LA) in human corneal specimens exhibiting 13 underlying pathologies. METHODS:Human corneal specimens were obtained from consenting subjects (n = 2 or n = 3 for each pathology; total sample size, n = 35). The pathological specimens wer...

journal_title：Cornea

authors： Tshionyi M,Shay E,Lunde E,Lin A,Han KY,Jain S,Chang JH,Azar DT

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To describe the viscoelastic marking technique, a novel marking technique of Descemet membrane endothelial keratoplasty (DMEK) grafts that enables usage of a single donor cornea for 2 surgeries-one that uses Descemet membrane and endothelium (DMEK) and the other using the stroma and Bowman layer. METHODS:A ret...

journal_title：Cornea

authors： Or L,Krakauer Y,Sorkin N,Knyazer B,Ashkenazy Z,Gushansky K,Dubinsky-Pertzov B,Gazit I,Einan-Lifshitz A

更新日期：2020-12-16 00:00:00

abstract：PURPOSE:To report the use of intracameral amphotericin B in the management of deep keratomycosis. METHODS:Four patients with deep keratomycosis unresponsive to conventional medical treatment underwent repeated intracameral injections of 5 microg amphotericin B in 0.1 mL 5% dextrose through a paracentesis. Three to 13 ...

journal_title：Cornea

authors： Kuriakose T,Kothari M,Paul P,Jacob P,Thomas R

更新日期：2002-10-01 00:00:00

abstract：PURPOSE:To examine the effect of successful repositioning/rebubbling of the graft on endothelial cell counts (ECCs) in eyes after Descemet stripping automated endothelial keratoplasty. METHODS:This retrospective study reviewed the outcomes of 58 eyes that underwent Descemet stripping automated endothelial keratoplasty...

journal_title：Cornea

authors： Mashor RS,Kaiserman I,Kumar N,Sansanayudh W,Rootman D

更新日期：2010-08-01 00:00:00

abstract：:The purpose of this study was to evaluate clinical ocular adenoviral isolates for differences among and within serotypes with respect to in vitro infectivity titers and clinical course. The study design included a retrospective chart review and the determination of in vitro infectivity titers (TCID90s) of 90 clinical ...

journal_title：Cornea

authors： Roba LA,Kowalski RP,Gordon AT,Romanowski EG,Gordon YJ

更新日期：1995-07-01 00:00:00

abstract：PURPOSE:To evaluate and report the efficacy of fibrin glue (FG)-assisted augmented amniotic membrane transplantation (AMT) in patients with large corneal perforations. METHODS:In a retrospective case series, 10 patients with corneal perforations more than 2 mm in diameter were treated with "FG-assisted augmented AMT."...

journal_title：Cornea

authors： Kim HK,Park HS

更新日期：2009-02-01 00:00:00

abstract：PURPOSE:The significance of ocular or corneal aberrations may be subject to misinterpretation whenever eyes with different pupil sizes or the application of different Zernike expansion orders are compared. A method is shown that uses simple mathematical interpolation techniques based on normal data to rapidly determine...

journal_title：Cornea

authors： Smolek MK

更新日期：2012-03-01 00:00:00