Combined use of subconjunctival and intracorneal bevacizumab injection for corneal neovascularization.

abstract：PURPOSE:To investigate the safety of intracameral injection of minimum bactericidal concentration (MBC) of povidone iodine (PI) on the corneal endothelium in a rabbit model as a proposed method of prophylaxis against postoperative endophthalmitis. METHODS:We included 32 New Zealand white rabbits in the study. Twenty-f...

journal_title：Cornea

authors： ElKitkat RS,Ebeid WM,Habib EK,Shoukry Y

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To determine the relationships among endothelial morphometric variables and contact lens-induced corneal swelling in a homogeneous sample of adapted contact-lens wearers. METHODS:Fifteen male subjects ranging in age from 20 to 40 years, all adapted to daily wear of hydrogel lenses, wore uniform-thickness lense...

journal_title：Cornea

authors： Erickson P,Doughty MJ,Comstock TL,Cullen AP

更新日期：1998-03-01 00:00:00

abstract：:The introduction of the excimer laser for keratorefractive surgery in the 1990 s permanently reshaped the treatment landscape for correcting refractive errors, such as myopia, hyperopia, and astigmatism. Until that point, these treatments had relied on less predictable techniques, such as radial keratotomy and automat...

journal_title：Cornea

authors： Azar DT,Chang JH,Han KY

更新日期：2012-11-01 00:00:00

abstract：PURPOSE:Quantitatively define and compare the nanoscale topography of the corneal epithelial basement membrane (anterior basement membrane) and Descemet's membrane (posterior basement membrane) of the human. METHODS:Human corneas not suitable for transplantation were obtained from the Wisconsin Eye Bank. The corneas w...

journal_title：Cornea

authors： Abrams GA,Schaus SS,Goodman SL,Nealey PF,Murphy CJ

更新日期：2000-01-01 00:00:00

abstract：PURPOSE:To report a case of direct contact xylene-related vacuolar keratopathy. METHODS:Interventional case report and review of the literature. RESULTS:Xylene keratopathy is a distinct clinical entity characterized by significantly decreased visual acuity, increased corneal thickness, and the presence of corneal epi...

journal_title：Cornea

authors： Trujillo F,Dang D,Starck T

更新日期：2003-01-01 00:00:00

abstract：PURPOSE:Corneal epithelial stem cells are deficient in cases of limbal disorders, leading to conjunctival epithelial ingrowth, vascularization, and eventually visual disturbance. We introduced the eye development-associated transcription factor pax6 to embryonic stem (ES) cells and tested whether pax6-transfected cells...

journal_title：Cornea

authors： Ueno H,Kurokawa MS,Kayama M,Homma R,Kumagai Y,Masuda C,Takada E,Tsubota K,Ueno S,Suzuki N

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:To report a case of nevirapine-induced Stevens-Johnson syndrome (SJS) misdiagnosed as viral keratitis. METHODS:A 35-year-old AIDS patient, on antiretroviral therapy (ART) with stavudine, nevirapine, and lamivudine, developed bilateral ocular congestion and irritation. He was being treated elsewhere for bilater...

journal_title：Cornea

authors： Jain V,Shome D,Natarajan S

更新日期：2008-04-01 00:00:00

abstract：PURPOSE:To report 7 cases of recurrent corneal neovascularization (NV) and lipid deposition after subconjunctival injection of bevacizumab for the treatment of corneal NV-induced lipid keratopathy. METHODS:We conducted a prospective interventional case series that included 20 eyes of chronic lipid keratopathy that rec...

journal_title：Cornea

authors： Chu HS,Chen TC,Hu FR,Chen WL

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:To report on a patient in whom hyperopic Implantable Collamer Lenses (ICL, STAAR Surgical, Nidau, Switzerland) and limbal relaxing incisions have been beneficial for the correction of hyperopic astigmatism after laser in situ keratomileusis (LASIK). METHODS:The 48-year-old man had undergone LASIK to correct hi...

journal_title：Cornea

authors： Kamiya K,Shimizu K,Komatsu M

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:To analyze the variations in tear quantity and quality after corneal collagen cross-linking (CXL) in patients with keratoconus. METHODS:This is a prospective observational study of 24 eyes with keratoconus that underwent epithelium-off CXL. The variables studied were tear film osmolarity, subjective symptoms (...

journal_title：Cornea

authors： Recalde JI,Acera A,Rodríguez-Agirretxe I,Sánchez-Tena MA,San-Cristóbal J,Durán JA

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of ultraviolet-corneal cross-linking (CXL) for treating infectious melting keratitis. METHODS:Five patients with infectious keratitis associated with corneal melting were treated with CXL at the outpatient departments of the Institut für Refraktive und Ophthalmo-Chirurgie and the eye h...

journal_title：Cornea

authors： Iseli HP,Thiel MA,Hafezi F,Kampmeier J,Seiler T

更新日期：2008-06-01 00:00:00

abstract：:Human type IV collagen discs were found to support proliferation and adhesion of rabbit corneal epithelial cells in tissue culture. To assess the biocompatibility of this synthetic collagen for epikeratoplasty, seven eyes of seven rhesus monkeys underwent epikeratoplasty with lenticules made of human type IV collagen....

journal_title：Cornea

authors： Thompson KP,Hanna KD,Gipson IK,Gravagna P,Waring GO 3rd,Johnson-Wint B

更新日期：1993-01-01 00:00:00

abstract：PURPOSE:To evaluate the effect of a single rebubbling procedure after Descemet membrane endothelial keratoplasty (DMEK) on corneal backscatter and endothelial cell loss (ECL). METHODS:Medical records of 130 consecutive DMEK cases (118 patients) were reviewed and 3 groups were formed: group 1 (n = 32), consisting of DM...

journal_title：Cornea

authors： Lazaridis A,Fydanaki O,Giallouros E,Georgalas I,Kymionis G,Sekundo W,Droutsas K

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:To evaluate if donor corneas obtained from deaths occurring because of septicemia can be used for corneal transplantation. STUDY DESIGN:Prospective study. METHODS:Eleven septicemic donor corneas were used in the study and 10 donor corneas from deaths because of causes other than septicemia were used as contro...

journal_title：Cornea

authors： Nagaraja H,Anandula V,Kugar T,Shivanna Y,Shetty R

更新日期：2016-08-01 00:00:00

abstract：:Previous studies suggest the existence of two separate and distinct mechanisms of endothelial wound healing (i.e., cell migration and cell spreading), which may be controlled by unique, injury-dependent, wound-related factors. The purpose of our study was to evaluate potential biologic mediators regulating healing of ...

journal_title：Cornea

authors： Petroll WM,Jester JV,Barry-Lane PA,Cavanagh HD

更新日期：1996-09-01 00:00:00

abstract：PURPOSE:To retrospectively evaluate the coexistence of congenital glaucoma with congenital hereditary endothelial dystrophy. METHODS:Ten infants presented to our hospital with diffuse corneal edema and bilaterally elevated intraocular pressure (IOP). These patients were diagnosed with congenital glaucoma. All patients...

journal_title：Cornea

authors： Ramamurthy B,Sachdeva V,Mandal AK,Vemuganti GK,Garg P,Sangwan VS

更新日期：2007-07-01 00:00:00

abstract：PURPOSE:We standardized quality-controlled cord blood serum (CBS)-based eye drops and evaluated the efficacy of 1-month CBS treatment in the healing of diseased corneal epithelium in severe dry eye (DE) patients. METHODS:Seventeen graft-versus-host disease (GVHD) and 13 Sjogren syndrome patients with severe persistent...

journal_title：Cornea

authors： Versura P,Profazio V,Buzzi M,Stancari A,Arpinati M,Malavolta N,Campos EC

更新日期：2013-04-01 00:00:00

abstract：:Limbal allograft transplantation was performed consecutively in 16 eyes with thermal or chemical burns (n = 5), Terrien's degeneration (n = 2), congenital sclerocornea (n = 1), Stevens-Johnson syndrome (n = 1), and chronic keratoconjunctivitis (n = 7), by transplanting randomly selected cadaver limbocorneal grafts to ...

journal_title：Cornea

authors： Tsai RJ,Tseng SC

更新日期：1994-09-01 00:00:00

abstract：PURPOSE:Peters anomaly is the most common cause of congenital corneal opacities. Although conservative management is often ineffective except in mild cases, surgical intervention in the form of penetrating keratoplasty is fraught with unpredictability and often has unacceptable postoperative outcomes. As such, there is...

journal_title：Cornea

authors： Soh YQ,Mehta JS

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To report keratouveitis arising from corneal penetration by a bristle worm seta (bristle). METHODS:We report on a 64-year-old woman presenting with uniocular pain, redness, reduced vision, discharge, and pustular rash of the hands after cleaning out her marine aquarium containing bristle worms and rubbing her ...

journal_title：Cornea

authors： Kirk J,Gunn D,Wong N,Minchin E,Darcy K

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:We report 2 cases in which cataract extraction with a foldable acrylic toric intraocular lens (IOL) implantation was used to correct (irregular) corneal astigmatism in patients with keratoconus and cataract. METHODS:Case 1 was a 78-year-old man with cataract and keratoconus in the left eye. He underwent phacoe...

journal_title：Cornea

authors： Visser N,Gast ST,Bauer NJ,Nuijts RM

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the outcome of penetrating keratoplasties, at the University Eye Hospital, Ludwig-Maximilians-University, Munich, Germany, using organ-cultured donor corneas and to identify preoperative risk factors, which may influence the event of graft failure. METHODS:In this study, 3...

journal_title：Cornea

authors： Yu AL,Kaiser M,Schaumberger M,Messmer E,Kook D,Welge-Lussen U

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:To compare the efficacy of conjunctival resection versus conjunctival resection with amniotic membrane graft (AMG) in patients with superior limbic keratoconjunctivitis not responsive to medical therapies. METHODS:In a retrospective and comparative study, 16 eyes of 9 patients with long-lasting superior limbic...

journal_title：Cornea

authors： Gris O,Plazas A,Lerma E,Güell JL,Pelegrín L,Elíes D

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:To test the hypothesis that patients with keratoconus and pellucid who have glaucoma or are glaucoma suspects have lower corneal hysteresis (CH) and/or corneal resistance factor (CRF) measurements compared with controls. METHODS:A prospective study at a tertiary eye center of patients with keratoconus and pell...

journal_title：Cornea

authors： Cohen EJ,Myers JS

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:To minimize recurrence and improve graft stability after pterygium surgery, conjunctival autograft adherence is done using fibrin glue (FG) or autologous blood coagulum (ABC). But there are studies that have reported conflicting or inconclusive results. This meta-analysis was conducted to evaluate the postopera...

journal_title：Cornea

authors： Maiti R,Mukherjee S,Hota D

更新日期：2017-10-01 00:00:00

abstract：:Mycobacterium fortuitum keratitis is an indolent infection of traumatized corneas in humans. To study this disorder in an animal model, 10(4) M fortuitum organisms (10 microliters) were inoculated into the stroma of both corneas of 16 New Zealand albino rabbits. Eight of the rabbits were also given bilateral subconjun...

journal_title：Cornea

authors： Paschal JF,Holland GN,Sison RF,Berlin OG,Bruckner DA,Dugel PU,Foos RY

更新日期：1992-11-01 00:00:00

abstract：PURPOSE:To examine the applicability of culture supernatant of human amniotic cells on basic fibroblast growth factor (bFGF)-induced corneal neovascularization. METHODS:Human amniotic epithelial and mesenchymal cells (AC) were obtained from human amniotic membranes by digesting with collagenase and maintained in serum...

journal_title：Cornea

authors： Kobayashi N,Kabuyama Y,Sasaki S,Kato K,Homma Y

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:To compare the outcome of bifold forceps and cartridge injector suture pull-through insertion techniques for Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS:A retrospective review was conducted of the medical records of all patients treated with DSAEK at the University of Iowa Hospitals ...

journal_title：Cornea

authors： Wendel LJ,Goins KM,Sutphin JE,Wagoner MD

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:To describe an impression cytology (IC) technique using a purpose-built, sterile, EYEPRIM IC device that can be coupled with a TRIzol reagent-based RNA extraction protocol to yield sufficient RNA for gene expression analysis. METHODS:IC samples using the EYEPRIM device were collected from the bulbar conjunctiv...

journal_title：Cornea

authors： Ganesalingam K,Ismail S,Craig JP,Sherwin T

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To investigate the tear levels of matrix metalloproteinases (MMPs), myeloperoxidase (MPO), and tissue inhibitor of metalloproteinase-1 in eyes after Boston keratoprosthesis type I (B-KPro) implantation and to correlate these markers with the established B-KPro prognostic categories. METHODS:Tear washes were co...

journal_title：Cornea

authors： Robert MC,Arafat SN,Spurr-Michaud S,Chodosh J,Dohlman CH,Gipson IK

更新日期：2016-07-01 00:00:00