Abstract:
PURPOSE:To assess the use of serial computed tomography (CT) in the detection of osteo-odonto-lamina resorption in osteo-odonto-keratoprosthesis (OOKP) and to investigate the use of new volumetric software, Advanced Lung Analysis software (3D-ALA; GE Healthcare), for detecting changes in OOKP laminar volume. METHODS:A retrospective assessment of the radiological databases and hospital records was performed for 22 OOKP patients treated at the National OOKP referral center in Brighton, United Kingdom. Three-dimensional surface reconstructions of the OOKP laminae were performed using stored CT data. For the 2-dimensional linear analysis, the linear dimensions of the reconstructed laminae were measured, compared with original measurements taken at the time of surgery, and then assigned a CT grade based on a predetermined resorption grading scale. The volumetric analysis involved calculating the laminar volumes using 3D-ALA. The effectiveness of 2-dimensional linear analysis, volumetric analysis, and clinical examination in detecting laminar resorption was compared. RESULTS:The mean change in laminar volume between the first and second scans was -6.67% (range, +10.13% to -24.86%). CT grades assigned to patients based on laminar dimension measurements remained the same, despite significant changes in laminar volumes. Clinical examination failed to identify 60% of patients who were found to have resorption on volumetric analysis. CONCLUSIONS:Currently, the detection of laminar resorption relies on clinical examination and the measurement of laminar dimensions on the 2- and 3-dimensional radiological images. Laminar volume measurement is a useful new addition to the armamentarium. It provides an objective tool that allows for a precise and reproducible assessment of laminar resorption.
journal_name
Corneajournal_title
Corneaauthors
Sipkova Z,Lam FC,Francis I,Herold J,Liu Cdoi
10.1097/ICO.0b013e31825425d0subject
Has Abstractpub_date
2013-04-01 00:00:00pages
401-6issue
4eissn
0277-3740issn
1536-4798journal_volume
32pub_type
杂志文章相关文献
CORNEA文献大全abstract:PURPOSE:To evaluate the efficacy and safety of topical bevacizumab on ocular surface neovascularization among patients with Stevens-Johnson syndrome. METHODS:This was a retrospective, interventional case report. Three eyes of 2 patients were examined. Bevacizumab (25 mg/mL) eyedrops were applied 4 times daily for a pe...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318158f6ad
更新日期:2008-01-01 00:00:00
abstract::The purpose of this study was to evaluate clinical ocular adenoviral isolates for differences among and within serotypes with respect to in vitro infectivity titers and clinical course. The study design included a retrospective chart review and the determination of in vitro infectivity titers (TCID90s) of 90 clinical ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199507000-00007
更新日期:1995-07-01 00:00:00
abstract:PURPOSE:To report a case of corneal ulceration and perforation after PRK connected with high doses of ketorolac tromethamine (Acula). METHODS:A 31-year-old man presented 5 days after PRK in the left eye with corneal ulceration and perforation requiring penetrating keratoplasty. The patient admitted to using Acular eve...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000179931.05275.dd
更新日期:2006-02-01 00:00:00
abstract::The records of 39 patients undergoing 40 consecutive penetrating keratoplasties were reviewed to identify donor factors that might correlate with the presence of an epithelial defect on the first postoperative day. Of the 40 transplanted corneas, 13 (32.5%) had no epithelial defect, 18 (45%) had some epithelial defect...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract:PURPOSE:To evaluate the long-term changes in anterior and posterior corneal irregular astigmatism and curvatures after small incision lenticule extraction (SMILE). METHODS:Fifty eyes of 28 patients underwent SMILE for myopic astigmatism. All procedures were performed using the VisuMax® femtosecond laser. A Scheimpflug...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001532
更新日期:2018-07-01 00:00:00
abstract:PURPOSE:To evaluate and compare the in vitro antimicrobial activity of levofloxacin versus ciprofloxacin and ofloxacin against ocular isolates from patients with bacterial conjunctivitis. METHODS:The in vitro antimicrobial susceptibilities of ocular isolates to levofloxacin, ofloxacin, and ciprofloxacin were determine...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200104000-00012
更新日期:2001-04-01 00:00:00
abstract:PURPOSE:Evaluation of efficacy of autologous platelet-rich plasma eyedrops as an adjunct to standard medical treatment as compared with standard medical treatment with artificial tears in acute ocular chemical injury. METHODS:Twenty eyes with grade III to grade V chemical injury were randomly assigned to 2 groups. Gro...
journal_title:Cornea
pub_type: 杂志文章,随机对照试验
doi:10.1097/ICO.0b013e3182114661
更新日期:2012-09-01 00:00:00
abstract:PURPOSE:Little research has been done on robotic ocular microsurgery. This study aims to demonstrate the feasibility of pterygium surgery using a robotic surgical system. METHODS:Robot-assisted pterygium surgery was performed on a 73-year-old patient with nasal and temporal pterygia using the DaVinci Si HD robotic Sur...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000561
更新日期:2015-10-01 00:00:00
abstract:PURPOSE:We characterized the presence of hemangiogenesis (HA) and lymphangiogenesis (LA) in human corneal specimens exhibiting 13 underlying pathologies. METHODS:Human corneal specimens were obtained from consenting subjects (n = 2 or n = 3 for each pathology; total sample size, n = 35). The pathological specimens wer...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31821dd986
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:To describe 3-dimensional optical coherence tomography (OCT) findings in a case of granular corneal dystrophy. METHODS:A 1310-nm high-speed swept-source OCT prototype was used to image the 3-dimensional structures of the cornea of a patient with granular corneal dystrophy. RESULTS:Three-dimensional OCT clearl...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31802e1e50
更新日期:2007-04-01 00:00:00
abstract:PURPOSE:The fourth-generation fluoroquinolone, moxifloxacin, covers most gram-positive and gram-negative isolates causing endophthalmitis. It is safe and effective for systemic and topical use, but only limited data are available on prophylactic intracameral administration to prevent endophthalmitis. This study uses a ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318191447b
更新日期:2009-06-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate preparation outcomes of tissue prepared for Descemet membrane endothelial keratoplasty (DMEK) from diabetic and nondiabetic donors. METHODS:In this nonrandomized, consecutive case series, DMEK grafts were prepared from diabetic and nondiabetic donors by experienced technic...
journal_title:Cornea
pub_type: 杂志文章,多中心研究
doi:10.1097/ICO.0000000000000262
更新日期:2014-11-01 00:00:00
abstract:PURPOSE:To investigate the morphological changes of corneal epithelium and subbasal nerves by in vivo confocal microscopy in patients with ocular surface disease (OSD) treated with cord blood serum (CBS) eye drops. METHODS:Twenty patients with OSD (mean age 61.1 ± 12.6 years) were included in this prospective 1-arm st...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001257
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:To study the factors affecting the time to onset of ocular graft-versus-host disease (GVHD) in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). METHODS:A retrospective chart review of 200 patients with ocular GVHD was performed to evaluate the association between various do...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000340
更新日期:2015-03-01 00:00:00
abstract::Streptococcal infections are an important cause of corneal ulcers, endophthalmitis, conjunctivitis, and dacryocystitis. We retrospectively reviewed 53 ocular streptococcal infections diagnosed and followed at Wills Eye Hospital between January 1, 1984, and July 1, 1986. Corneal ulcers (23 of 53; 43%) and endophthalmit...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:PURPOSE:To present the clinical outcome of 2 cases of severe dry eye associated with Nivolumab, with 1 case progressing to corneal perforation. DESIGN:Case report. CASE 1:: A 58-year-old man with metastatic melanoma was referred for the management of severe bilateral dry eyes after undergoing his sixth cycle of Nivol...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000724
更新日期:2016-03-01 00:00:00
abstract:PURPOSE:To assess the repeatability of densitometry, a measure of corneal haze, in the control (group I), keratoconic (group II), and postcollagen cross-linking (CXL, group III) eyes as measured on Scheimpflug imaging. METHODS:Densitometry values for 160 eyes of 160 patients (50 eyes of 50 patients in group I, 50 eyes...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000800
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:We analyzed laboratory results from corneal ulcers seen from 1976 to 1999 at the Francis I. Proctor Foundation, a referral center in San Francisco, to determine the relative frequencies of pathogens and to analyze for trends in frequencies of the most common pathogens. The results were compared with a previou...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200405000-00009
更新日期:2004-05-01 00:00:00
abstract::Epithelium plays a very important structural and functional role in the cornea and conjunctiva. Evaluation of the epithelium is the first step in diagnosing many pathologic states. We have developed a new technique for the in vivo staining of nuclei of corneal and conjunctival epithelium in rabbits and guinea pigs. Se...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract:PURPOSE:The aim of this study was to assess the possibility of light damage to the retina by a surgical microscope during implantation of a Boston Keratoprosthesis (B-KPro) in rabbits. METHODS:The retinal irradiance from a Zeiss OPMI Lumera S7 operating microscope was measured at the working distance (16.5 cm). Light ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000029
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:To compare paired human corneas after storage at 4 degrees C in Chen medium (CM) and Optisol-GS medium (OM) for 7, 10, 14, and 21 days. METHODS:One cornea of each pair from nine human donors was randomly stored in either CM or OM, with its mate cornea stored in the other medium. Three pairs of corneas were sto...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200011000-00005
更新日期:2000-11-01 00:00:00
abstract:PURPOSE:We studied the possibility that tranilast, an antiallergic and antiproliferative drug, may be beneficial for the treatment of pterygium. METHODS:Pterygium-derived cells were identified by immunohistochemical methods. Growth rate of pterygium-derived cells was determined by using a hemocytometer. Chemotaxis was...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200005000-00021
更新日期:2000-05-01 00:00:00
abstract:PURPOSE:The purpose of this study was to report the first case of fungal keratitis resulting from Thielavia sp. METHODS:We conducted a retrospective chart review. RESULTS:A 10-year old girl presented 2 weeks after ocular plant injury with pain and corneal stromal infiltration with central ulceration and ill-defined m...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31819717f4
更新日期:2009-10-01 00:00:00
abstract::The mechanism of ocular surface allergy in the forms of atopic conjunctivitis and vernal keratoconjunctivitis has been highlighted by specific functions of chemokines. In the context of late-phase allergic responses, these molecules have key roles in recruitment and activation of leukocytes. Their interaction with lig...
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/01.ico.0000136671.50777.fe
更新日期:2004-11-01 00:00:00
abstract:PURPOSE:We describe the first case of minimally invasive corneal neurotization with the great auricular nerve (GAN) to treat unilateral neurotrophic keratopathy. We assessed corneal sensation and reinnervation by esthesiometry and confocal microscopy over 12 months of follow-up, and we provide a detailed description of...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001549
更新日期:2018-05-01 00:00:00
abstract:PURPOSE:To evaluate the stromal interface quality after femtosecond laser full lamellar cuts in gamma-irradiated corneas (VisionGraft sterile cornea) and to determine the limits of the cut depth using the VisionGraft as donor corneas for laser-assisted lamellar anterior keratoplasty. METHODS:Fourteen VisionGraft corne...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000614
更新日期:2015-11-01 00:00:00
abstract:PURPOSE:To determine the acute endothelial cell damage from trephination and tissue insertion in endothelial keratoplasty (EK) surgery. The influence of insertion technique (forceps insertion vs "pull-through" insertion) of donor tissue and incision size (3 vs 5 mm length) was assessed. METHODS:Forty precut 8.-mm-diam...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318182a4d3
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:Investigators have discovered that topical antiglaucoma drugs may induce meibomian gland dysfunction. This response may contribute to the dry eye disease commonly found in patients with glaucoma taking such medications. We hypothesize that drug action involves a direct effect on human meibomian gland epithelial...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001181
更新日期:2017-06-01 00:00:00
abstract:PURPOSE:To demonstrate the use of anterior segment optical coherence tomography (ASOCT) in planning phototherapeutic keratectomy (PTK) removal of central corneal stromal scarring. METHODS:A 62-year-old male presented with central corneal scars associated with significant ocular surface disease. Videokeratographies obt...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181930b9f
更新日期:2009-09-01 00:00:00
abstract::A randomized, double-blind, placebo-controlled, multicenter clinical trial was conducted in five centers to assess safety, ocular tolerance, and efficacy of an ophthalmic solution of epidermal growth factor (EGF) for the treatment of traumatic corneal epithelial defects. One hundred four patients completed the study: ...
journal_title:Cornea
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1097/00003226-199207000-00007
更新日期:1992-07-01 00:00:00