Serial 3-dimensional computed tomography and a novel method of volumetric analysis for the evaluation of the osteo-odonto-keratoprosthesis.

Abstract:

PURPOSE:To assess the use of serial computed tomography (CT) in the detection of osteo-odonto-lamina resorption in osteo-odonto-keratoprosthesis (OOKP) and to investigate the use of new volumetric software, Advanced Lung Analysis software (3D-ALA; GE Healthcare), for detecting changes in OOKP laminar volume. METHODS:A retrospective assessment of the radiological databases and hospital records was performed for 22 OOKP patients treated at the National OOKP referral center in Brighton, United Kingdom. Three-dimensional surface reconstructions of the OOKP laminae were performed using stored CT data. For the 2-dimensional linear analysis, the linear dimensions of the reconstructed laminae were measured, compared with original measurements taken at the time of surgery, and then assigned a CT grade based on a predetermined resorption grading scale. The volumetric analysis involved calculating the laminar volumes using 3D-ALA. The effectiveness of 2-dimensional linear analysis, volumetric analysis, and clinical examination in detecting laminar resorption was compared. RESULTS:The mean change in laminar volume between the first and second scans was -6.67% (range, +10.13% to -24.86%). CT grades assigned to patients based on laminar dimension measurements remained the same, despite significant changes in laminar volumes. Clinical examination failed to identify 60% of patients who were found to have resorption on volumetric analysis. CONCLUSIONS:Currently, the detection of laminar resorption relies on clinical examination and the measurement of laminar dimensions on the 2- and 3-dimensional radiological images. Laminar volume measurement is a useful new addition to the armamentarium. It provides an objective tool that allows for a precise and reproducible assessment of laminar resorption.

journal_name

Cornea

journal_title

Cornea

authors

Sipkova Z,Lam FC,Francis I,Herold J,Liu C

doi

10.1097/ICO.0b013e31825425d0

subject

Has Abstract

pub_date

2013-04-01 00:00:00

pages

401-6

issue

4

eissn

0277-3740

issn

1536-4798

journal_volume

32

pub_type

杂志文章

相关文献

CORNEA文献大全
  • Topical bevacizumab and ocular surface neovascularization in patients with stevens-johnson syndrome.

    abstract:PURPOSE:To evaluate the efficacy and safety of topical bevacizumab on ocular surface neovascularization among patients with Stevens-Johnson syndrome. METHODS:This was a retrospective, interventional case report. Three eyes of 2 patients were examined. Bevacizumab (25 mg/mL) eyedrops were applied 4 times daily for a pe...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318158f6ad

    authors: Uy HS,Chan PS,Ang RE

    更新日期:2008-01-01 00:00:00

  • Adenoviral ocular isolates demonstrate serotype-dependent differences in in vitro infectivity titers and clinical course.

    abstract::The purpose of this study was to evaluate clinical ocular adenoviral isolates for differences among and within serotypes with respect to in vitro infectivity titers and clinical course. The study design included a retrospective chart review and the determination of in vitro infectivity titers (TCID90s) of 90 clinical ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199507000-00007

    authors: Roba LA,Kowalski RP,Gordon AT,Romanowski EG,Gordon YJ

    更新日期:1995-07-01 00:00:00

  • Corneal ulceration and perforation with ketorolac tromethamine (Acular) use after PRK.

    abstract:PURPOSE:To report a case of corneal ulceration and perforation after PRK connected with high doses of ketorolac tromethamine (Acula). METHODS:A 31-year-old man presented 5 days after PRK in the left eye with corneal ulceration and perforation requiring penetrating keratoplasty. The patient admitted to using Acular eve...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000179931.05275.dd

    authors: Mian SI,Gupta A,Pineda R 2nd

    更新日期:2006-02-01 00:00:00

  • Donor factors associated with epithelial defects after penetrating keratoplasty.

    abstract::The records of 39 patients undergoing 40 consecutive penetrating keratoplasties were reviewed to identify donor factors that might correlate with the presence of an epithelial defect on the first postoperative day. Of the 40 transplanted corneas, 13 (32.5%) had no epithelial defect, 18 (45%) had some epithelial defect...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Kim T,Palay DA,Lynn M

    更新日期:1996-09-01 00:00:00

  • Corneal Irregular Astigmatism and Curvature Changes After Small Incision Lenticule Extraction: Three-Year Follow-Up.

    abstract:PURPOSE:To evaluate the long-term changes in anterior and posterior corneal irregular astigmatism and curvatures after small incision lenticule extraction (SMILE). METHODS:Fifty eyes of 28 patients underwent SMILE for myopic astigmatism. All procedures were performed using the VisuMax® femtosecond laser. A Scheimpflug...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001532

    authors: Sideroudi H,Lazaridis A,Messerschmidt-Roth A,Labiris G,Kozobolis V,Sekundo W

    更新日期:2018-07-01 00:00:00

  • In vitro susceptibilities of bacterial ocular isolates to fluoroquinolones.

    abstract:PURPOSE:To evaluate and compare the in vitro antimicrobial activity of levofloxacin versus ciprofloxacin and ofloxacin against ocular isolates from patients with bacterial conjunctivitis. METHODS:The in vitro antimicrobial susceptibilities of ocular isolates to levofloxacin, ofloxacin, and ciprofloxacin were determine...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200104000-00012

    authors: Graves A,Henry M,O'Brien TP,Hwang DG,Van Buskirk A,Trousdale MD

    更新日期:2001-04-01 00:00:00

  • Topical autologous platelet-rich plasma eyedrops for acute corneal chemical injury.

    abstract:PURPOSE:Evaluation of efficacy of autologous platelet-rich plasma eyedrops as an adjunct to standard medical treatment as compared with standard medical treatment with artificial tears in acute ocular chemical injury. METHODS:Twenty eyes with grade III to grade V chemical injury were randomly assigned to 2 groups. Gro...

    journal_title:Cornea

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/ICO.0b013e3182114661

    authors: Panda A,Jain M,Vanathi M,Velpandian T,Khokhar S,Dada T

    更新日期:2012-09-01 00:00:00

  • Robotically Assisted Pterygium Surgery: First Human Case.

    abstract:PURPOSE:Little research has been done on robotic ocular microsurgery. This study aims to demonstrate the feasibility of pterygium surgery using a robotic surgical system. METHODS:Robot-assisted pterygium surgery was performed on a 73-year-old patient with nasal and temporal pterygia using the DaVinci Si HD robotic Sur...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000561

    authors: Bourcier T,Chammas J,Becmeur PH,Danan J,Sauer A,Gaucher D,Liverneaux P,Mutter D

    更新日期:2015-10-01 00:00:00

  • Hemangiogenesis and lymphangiogenesis in corneal pathology.

    abstract:PURPOSE:We characterized the presence of hemangiogenesis (HA) and lymphangiogenesis (LA) in human corneal specimens exhibiting 13 underlying pathologies. METHODS:Human corneal specimens were obtained from consenting subjects (n = 2 or n = 3 for each pathology; total sample size, n = 35). The pathological specimens wer...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31821dd986

    authors: Tshionyi M,Shay E,Lunde E,Lin A,Han KY,Jain S,Chang JH,Azar DT

    更新日期:2012-01-01 00:00:00

  • Three-dimensional optical coherence tomography of granular corneal dystrophy.

    abstract:PURPOSE:To describe 3-dimensional optical coherence tomography (OCT) findings in a case of granular corneal dystrophy. METHODS:A 1310-nm high-speed swept-source OCT prototype was used to image the 3-dimensional structures of the cornea of a patient with granular corneal dystrophy. RESULTS:Three-dimensional OCT clearl...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31802e1e50

    authors: Miura M,Mori H,Watanabe Y,Usui M,Kawana K,Oshika T,Yatagai T,Yasuno Y

    更新日期:2007-04-01 00:00:00

  • Intracameral moxifloxacin: in vitro safety on human ocular cells.

    abstract:PURPOSE:The fourth-generation fluoroquinolone, moxifloxacin, covers most gram-positive and gram-negative isolates causing endophthalmitis. It is safe and effective for systemic and topical use, but only limited data are available on prophylactic intracameral administration to prevent endophthalmitis. This study uses a ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318191447b

    authors: Kernt M,Neubauer AS,Liegl RG,Lackerbauer CA,Eibl KH,Alge CS,Ulbig MW,A AK

    更新日期:2009-06-01 00:00:00

  • Diabetes mellitus increases risk of unsuccessful graft preparation in Descemet membrane endothelial keratoplasty: a multicenter study.

    abstract:PURPOSE:The aim of this study was to evaluate preparation outcomes of tissue prepared for Descemet membrane endothelial keratoplasty (DMEK) from diabetic and nondiabetic donors. METHODS:In this nonrandomized, consecutive case series, DMEK grafts were prepared from diabetic and nondiabetic donors by experienced technic...

    journal_title:Cornea

    pub_type: 杂志文章,多中心研究

    doi:10.1097/ICO.0000000000000262

    authors: Greiner MA,Rixen JJ,Wagoner MD,Schmidt GA,Stoeger CG,Straiko MD,Zimmerman MB,Kitzmann AS,Goins KM

    更新日期:2014-11-01 00:00:00

  • Efficacy of 2-Month Treatment With Cord Blood Serum Eye Drops in Ocular Surface Disease: An In Vivo Confocal Microscopy Study.

    abstract:PURPOSE:To investigate the morphological changes of corneal epithelium and subbasal nerves by in vivo confocal microscopy in patients with ocular surface disease (OSD) treated with cord blood serum (CBS) eye drops. METHODS:Twenty patients with OSD (mean age 61.1 ± 12.6 years) were included in this prospective 1-arm st...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001257

    authors: Giannaccare G,Buzzi M,Fresina M,Velati C,Versura P

    更新日期:2017-08-01 00:00:00

  • Onset of ocular graft-versus-host disease symptoms after allogeneic hematopoietic stem cell transplantation.

    abstract:OBJECTIVE:To study the factors affecting the time to onset of ocular graft-versus-host disease (GVHD) in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). METHODS:A retrospective chart review of 200 patients with ocular GVHD was performed to evaluate the association between various do...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000340

    authors: Shikari H,Amparo F,Saboo U,Dana R

    更新日期:2015-03-01 00:00:00

  • Ocular streptococcal infections.

    abstract::Streptococcal infections are an important cause of corneal ulcers, endophthalmitis, conjunctivitis, and dacryocystitis. We retrospectively reviewed 53 ocular streptococcal infections diagnosed and followed at Wills Eye Hospital between January 1, 1984, and July 1, 1986. Corneal ulcers (23 of 53; 43%) and endophthalmit...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Jones S,Cohen EJ,Arentsen JJ,Laibson PR

    更新日期:1988-01-01 00:00:00

  • Cyclosporine for Dry Eye Associated With Nivolumab: A Case Progressing to Corneal Perforation.

    abstract:PURPOSE:To present the clinical outcome of 2 cases of severe dry eye associated with Nivolumab, with 1 case progressing to corneal perforation. DESIGN:Case report. CASE 1:: A 58-year-old man with metastatic melanoma was referred for the management of severe bilateral dry eyes after undergoing his sixth cycle of Nivol...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000724

    authors: Nguyen AT,Elia M,Materin MA,Sznol M,Chow J

    更新日期:2016-03-01 00:00:00

  • Corneal Densitometry: Repeatability in Eyes With Keratoconus and Postcollagen Cross-Linking.

    abstract:PURPOSE:To assess the repeatability of densitometry, a measure of corneal haze, in the control (group I), keratoconic (group II), and postcollagen cross-linking (CXL, group III) eyes as measured on Scheimpflug imaging. METHODS:Densitometry values for 160 eyes of 160 patients (50 eyes of 50 patients in group I, 50 eyes...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000800

    authors: Pahuja N,Shetty R,Subbiah P,Nagaraja H,Nuijts RM,Jayadev C

    更新日期:2016-06-01 00:00:00

  • Trends in the etiology of infectious corneal ulcers at the F. I. Proctor Foundation.

    abstract:OBJECTIVE:We analyzed laboratory results from corneal ulcers seen from 1976 to 1999 at the Francis I. Proctor Foundation, a referral center in San Francisco, to determine the relative frequencies of pathogens and to analyze for trends in frequencies of the most common pathogens. The results were compared with a previou...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200405000-00009

    authors: Varaprasathan G,Miller K,Lietman T,Whitcher JP,Cevallos V,Okumoto M,Margolis TP,Yinghui M,Cunningham ET Jr

    更新日期:2004-05-01 00:00:00

  • In vivo corneal and conjunctival epithelial nuclear stain.

    abstract::Epithelium plays a very important structural and functional role in the cornea and conjunctiva. Evaluation of the epithelium is the first step in diagnosing many pathologic states. We have developed a new technique for the in vivo staining of nuclei of corneal and conjunctival epithelium in rabbits and guinea pigs. Se...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Wander AH,Neumeister RD,Tschismadia I,Choromokos EA,Masukawa T

    更新日期:1985-01-01 00:00:00

  • Very low risk of light-induced retinal damage during Boston keratoprosthesis surgery: a rabbit study.

    abstract:PURPOSE:The aim of this study was to assess the possibility of light damage to the retina by a surgical microscope during implantation of a Boston Keratoprosthesis (B-KPro) in rabbits. METHODS:The retinal irradiance from a Zeiss OPMI Lumera S7 operating microscope was measured at the working distance (16.5 cm). Light ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000029

    authors: Salvador-Culla B,Behlau I,Sayegh RR,Stacy RC,Dohlman CH,Delori F

    更新日期:2014-02-01 00:00:00

  • In vitro comparison of Chen medium and Optisol-GS medium for human corneal storage.

    abstract:PURPOSE:To compare paired human corneas after storage at 4 degrees C in Chen medium (CM) and Optisol-GS medium (OM) for 7, 10, 14, and 21 days. METHODS:One cornea of each pair from nine human donors was randomly stored in either CM or OM, with its mate cornea stored in the other medium. Three pairs of corneas were sto...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200011000-00005

    authors: Nelson LR,Hodge DO,Bourne WM

    更新日期:2000-11-01 00:00:00

  • Inhibitory effects of tranilast on the proliferation and functions of human pterygium-derived fibroblasts.

    abstract:PURPOSE:We studied the possibility that tranilast, an antiallergic and antiproliferative drug, may be beneficial for the treatment of pterygium. METHODS:Pterygium-derived cells were identified by immunohistochemical methods. Growth rate of pterygium-derived cells was determined by using a hemocytometer. Chemotaxis was...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200005000-00021

    authors: Isaji M,Kikuchi S,Miyata H,Ajisawa Y,Araki-Inazawa K,Tsukamoto Y,Amano Y

    更新日期:2000-05-01 00:00:00

  • Keratitis resulting from Thielavia subthermophila Mouchacca.

    abstract:PURPOSE:The purpose of this study was to report the first case of fungal keratitis resulting from Thielavia sp. METHODS:We conducted a retrospective chart review. RESULTS:A 10-year old girl presented 2 weeks after ocular plant injury with pain and corneal stromal infiltration with central ulceration and ill-defined m...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31819717f4

    authors: Theoulakis P,Goldblum D,Zimmerli S,Muehlethaler K,Frueh BE

    更新日期:2009-10-01 00:00:00

  • Roles of chemokines in ocular allergy and possible therapeutic strategies.

    abstract::The mechanism of ocular surface allergy in the forms of atopic conjunctivitis and vernal keratoconjunctivitis has been highlighted by specific functions of chemokines. In the context of late-phase allergic responses, these molecules have key roles in recruitment and activation of leukocytes. Their interaction with lig...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/01.ico.0000136671.50777.fe

    authors: Miyazaki D,Nakamura T,Komatsu N,Nawata N,Ikeda Y,Inoue Y,Higashi H,Ono SJ

    更新日期:2004-11-01 00:00:00

  • Corneal Neurotization With a Great Auricular Nerve Graft: Effective Reinnervation Demonstrated by In Vivo Confocal Microscopy.

    abstract:PURPOSE:We describe the first case of minimally invasive corneal neurotization with the great auricular nerve (GAN) to treat unilateral neurotrophic keratopathy. We assessed corneal sensation and reinnervation by esthesiometry and confocal microscopy over 12 months of follow-up, and we provide a detailed description of...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001549

    authors: Benkhatar H,Levy O,Goemaere I,Borderie V,Laroche L,Bouheraoua N

    更新日期:2018-05-01 00:00:00

  • Laboratory Evaluation of Femtosecond Laser Lamellar Cuts in Gamma-Irradiated Corneas.

    abstract:PURPOSE:To evaluate the stromal interface quality after femtosecond laser full lamellar cuts in gamma-irradiated corneas (VisionGraft sterile cornea) and to determine the limits of the cut depth using the VisionGraft as donor corneas for laser-assisted lamellar anterior keratoplasty. METHODS:Fourteen VisionGraft corne...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000614

    authors: Zhang C,Liu L,Tang M,Li Y,Chamberlain W,Huang D

    更新日期:2015-11-01 00:00:00

  • Endothelial keratoplasty: the influence of insertion techniques and incision size on donor endothelial survival.

    abstract:PURPOSE:To determine the acute endothelial cell damage from trephination and tissue insertion in endothelial keratoplasty (EK) surgery. The influence of insertion technique (forceps insertion vs "pull-through" insertion) of donor tissue and incision size (3 vs 5 mm length) was assessed. METHODS:Forty precut 8.-mm-diam...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318182a4d3

    authors: Terry MA,Saad HA,Shamie N,Chen ES,Phillips PM,Friend DJ,Holiman JD,Stoeger C

    更新日期:2009-01-01 00:00:00

  • Influence of Pilocarpine and Timolol on Human Meibomian Gland Epithelial Cells.

    abstract:PURPOSE:Investigators have discovered that topical antiglaucoma drugs may induce meibomian gland dysfunction. This response may contribute to the dry eye disease commonly found in patients with glaucoma taking such medications. We hypothesize that drug action involves a direct effect on human meibomian gland epithelial...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001181

    authors: Zhang Y,Kam WR,Liu Y,Chen X,Sullivan DA

    更新日期:2017-06-01 00:00:00

  • Anterior segment optical coherence tomography for transepithelial phototherapeutic keratectomy in central corneal stromal scarring.

    abstract:PURPOSE:To demonstrate the use of anterior segment optical coherence tomography (ASOCT) in planning phototherapeutic keratectomy (PTK) removal of central corneal stromal scarring. METHODS:A 62-year-old male presented with central corneal scars associated with significant ocular surface disease. Videokeratographies obt...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181930b9f

    authors: Ma JJ,Tseng SS,Yarascavitch BA

    更新日期:2009-09-01 00:00:00

  • Epidermal growth factor and corneal wound healing. A multicenter study.

    abstract::A randomized, double-blind, placebo-controlled, multicenter clinical trial was conducted in five centers to assess safety, ocular tolerance, and efficacy of an ophthalmic solution of epidermal growth factor (EGF) for the treatment of traumatic corneal epithelial defects. One hundred four patients completed the study: ...

    journal_title:Cornea

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/00003226-199207000-00007

    authors: Pastor JC,Calonge M

    更新日期:1992-07-01 00:00:00