Efficacy of Corneal Collagen Cross-Linking for the Treatment of Keratoconus: A Systematic Review and Meta-Analysis.

abstract：PURPOSE:To investigate the long-term effect and safety of collagen cross-linking (CXL) on patients with bullous keratopathy (BK) in a randomized control manner. It is, to our knowledge, the first randomized control study on the effect of CXL on BK. METHODS:Subjects were randomized to receive CXL as in the standard pro...

journal_title：Cornea

authors： Choy BNK,Ng ALK,Zhu MM,Liu CC,Xu S,Lai JSM

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:The aim of this study was to estimate both the direct and indirect annual cost of managing dry eye disease (DED) in the United States from a societal and a payer's perspective. METHODS:A decision analytic model was developed to estimate the annual cost for managing a cohort of patients with dry eye with differ...

journal_title：Cornea

authors： Yu J,Asche CV,Fairchild CJ

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:We characterized the presence of hemangiogenesis (HA) and lymphangiogenesis (LA) in human corneal specimens exhibiting 13 underlying pathologies. METHODS:Human corneal specimens were obtained from consenting subjects (n = 2 or n = 3 for each pathology; total sample size, n = 35). The pathological specimens wer...

journal_title：Cornea

authors： Tshionyi M,Shay E,Lunde E,Lin A,Han KY,Jain S,Chang JH,Azar DT

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To investigate the effects of diquafosol sodium (DQS) eye drops, a purinergic P2Y2 receptor agonist, on tear film stability in patients with unstable tear film (UTF). METHODS:Two prospective studies were conducted. One was an exploratory nonrandomized trial on 39 eyes with dry eye symptoms and short tear film ...

journal_title：Cornea

authors： Shimazaki-Den S,Iseda H,Dogru M,Shimazaki J

更新日期：2013-08-01 00:00:00

abstract：PURPOSE:To report the clinical impact of conjunctivochalasis on the ocular surface by evaluating the effect of a new concept of conjunctivochalasis operation on the resolution of patients' symptoms and corneal epithelial damage. Also, the association of inflammation with conjunctivochalasis is examined. PATIENTS AND M...

journal_title：Cornea

authors： Yokoi N,Komuro A,Nishii M,Inagaki K,Tanioka H,Kawasaki S,Kinoshita S

更新日期：2005-11-01 00:00:00

abstract：PURPOSE:To describe the technique and outcomes of limbal stem cell-sparing lamellar keratoplasty (LSCS-LKP) for the management of advanced keratoglobus (KGB). METHODS:In a sequential interventional case series from March 2010 to December 2012, 8 eyes of 6 patients with advanced KGB underwent an LSCS-LKP. Three patient...

journal_title：Cornea

authors： Karimian F,Baradaran-Rafii A,Faramarzi A,Akbari M

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To determine the changes of corneal thickness and curvature of human corneal grafts in organ culture medium II, containing dextran T500 6%, before keratoplasty. METHODS:We examined the tomography of 24 corneas from our eye bank transferred from medium I into medium II. Images were repeated hourly during 24 hou...

journal_title：Cornea

authors： Hamon L,Daas L,Mäurer S,Weinstein I,Quintin A,Schulz K,Langenbucher A,Seitz B

更新日期：2020-12-04 00:00:00

abstract：PURPOSE:Ocular local anesthetics currently used in routine clinical practice for corneal anesthesia are short acting and their ability to delay corneal healing makes them unsuitable for long-term use. In this study, we examined the effect of the site 1 sodium channel blocker tetrodotoxin (TTX) on the duration of cornea...

journal_title：Cornea

authors： Wang L,Shankarappa SA,Tong R,Ciolino JB,Tsui JH,Chiang HH,Kohane DS

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of transepithelial cross-linking (CXL) in keratoconic eyes after Intacs implantation. PATIENTS AND METHODS:Twenty-five eyes of 17 patients with bilateral keratoconus underwent Intacs implantation with subsequent cross-linking (CXL) treatment. Inclusion criteria were absence of corneal ...

journal_title：Cornea

authors： Ertan A,Karacal H,Kamburoğlu G

更新日期：2009-08-01 00:00:00

abstract：PURPOSE:We present the clinicopathologic correlations of two case and two other clinical cases of topical anesthetic abuse keratopathy that were originally diagnosed as Acanthamoeba keratitis because of ring keratitis presentation and characteristic history. METHODS:Four patients who were referred to us with suspected...

journal_title：Cornea

authors： Varga JH,Rubinfeld RS,Wolf TC,Stutzman RD,Peele KA,Clifford WS,Madigan W

更新日期：1997-07-01 00:00:00

abstract：PURPOSE:This study was designed to determine how patients with pellucid marginal corneal degeneration (PMCD) are managed in a tertiary corneal practice. METHODS:A retrospective chart review of 45 patients with PMCD from a corneal referral practice was performed. Information collected from the medical records included ...

journal_title：Cornea

authors： Tzelikis PF,Cohen EJ,Rapuano CJ,Hammersmith KM,Laibson PR

更新日期：2005-07-01 00:00:00

abstract：:We retrospectively examined Michigan Eye-Bank and Transplantation Center data on all eye/cornea donors in Michigan and Illinois for whom human immunodeficiency virus (HIV) antibody screening results were available. This was done to compare the HIV-antibody positive serology rate in hospital versus medical examiner don...

journal_title：Cornea

authors： Danneffel MB,Sugar A

更新日期：1990-07-01 00:00:00

abstract：PURPOSE:To report a 64-year-old woman's case of infectious crystalline keratopathy (ICK) that occurred 9 years after the penetrating keratoplasty (PKP). METHODS:This study includes clinical history and histopathologic findings of the case. RESULTS:As historic background, the patient underwent PKP for lattice dystroph...

journal_title：Cornea

authors： Matsumoto A,Sano Y,Nishida K,Yokoi N,Hara J,Kinoshita S

更新日期：1998-01-01 00:00:00

abstract：PURPOSE:To describe severe acute corneal hydrops in a patient with previously undiagnosed keratoconus, in which anterior segment optical coherence tomography (AS-OCT) revealed a protruding ridge of tissue on either side of Descemet membrane (DM) break, treated successfully with ultrathin Descemet-stripping automated en...

journal_title：Cornea

authors： Blitzer AL,Liles CA,Harocopos GJ,Reidy JJ,Farooq AV

更新日期：2020-09-09 00:00:00

abstract：PURPOSE:To evaluate trends in the acquisition, storage, and utilization of donated corneal tissue in New Zealand, 2000 to 2009. METHODS:The New Zealand National Eye Bank records were analyzed for the decade January 2000 to December 2009. Variables analyzed included donor demographics (age, sex, and ethnicity), donor s...

journal_title：Cornea

authors： Cunningham WJ,Moffatt SL,Brookes NH,Twohill HC,Pendergrast DG,Stewart JM,McGhee CN

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:To evaluate the results of a combined approach of cicatrix lysis, intraoperative mitomycin C (MMC) application, oral mucosal transplantation (OMT), and amniotic membrane transplantation (AMT) for surgery of severe symblepharon. METHODS:This prospective study included 32 eyes with severe symblepharon in which a...

journal_title：Cornea

authors： Kheirkhah A,Ghaffari R,Kaghazkanani R,Hashemi H,Behrouz MJ,Raju VK

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:To report an unusual case of epithelial ingrowth after phacoemulsification with posterior chamber intraocular lens implantation in a patient with recurrent pterygium, along with confocal microscopy findings of epithelial ingrowth. METHODS:This is a case report and review of the literature. RESULTS:A healthy 6...

journal_title：Cornea

authors： Khurana S,Gupta PC,R B,Sharma VK,Ram J

更新日期：2020-01-01 00:00:00

abstract：:Posterior polymorphous corneal dystrophy (PPD) is a rare bilateral, autosomal-dominant disease. The presence of the epitheliumlike endothelium and the thickening of Descemet's membrane by the posterior collagenous layer (PCL) has been reported in the majority of published cases. Reepithelialization of the posterior co...

journal_title：Cornea

authors： Sekundo W,Lee WR,Aitken DA,Kirkness CM

更新日期：1994-11-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of superficial keratectomy and conjunctival advancement hood flap (SKCAHF) for the treatment of bullous keratopathy in canine patients. METHODS:Nine dogs (12 eyes) diagnosed with progressive corneal edema underwent superficial keratectomy followed by placement of conjunctival advanceme...

journal_title：Cornea

authors： Horikawa T,Thomasy SM,Stanley AA,Calderon AS,Li J,Linton LL,Murphy CJ

更新日期：2016-10-01 00:00:00

abstract：:We describe the findings in nine Asian-Indian patients with gelatinous droplike corneal dystrophy (GDCD). Most patients showed initial signs of bilateral decreased vision and photophobia at an early age. The siblings were affected in four cases, and parental consanguinity was recorded in seven cases. We classified the...

journal_title：Cornea

authors： Li S,Edward DP,Ratnakar KS,Reddy M,Tso MO

更新日期：1996-07-01 00:00:00

abstract：PURPOSE:To present a case series of patients with Boston keratoprosthesis type I (KPro) who have had successful ptosis repair with Müller muscle-conjunctiva resection (MMCR). METHODS:Patients with KPros managed with MMCR for ptosis were identified. Records were examined to obtain preoperative and postoperative visual ...

journal_title：Cornea

authors： Lim JM,Bang GM,Cortina MS,de la Cruz J,Setabutr P

更新日期：2014-03-01 00:00:00

abstract：:This report describes computerized image enhancement and analysis from the digitized image of a wide-field specular micrograph to produce an output of frequency distribution of cell areas. The steps involved including image smoothing and averaging, followed by automated scanning to detect individual cell boundaries, a...

journal_title：Cornea

authors： Hirst LW,Sterner RE,Grant DG

更新日期：1984-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to introduce a newly developed graft inserter for Descemet stripping automated endothelial keratoplasty, which can be readily used with 1 hand, and to examine endothelial cell loss (ECL) after graft insertion using this new inserter in an ex vivo rabbit model. METHODS:Rabbit corneal g...

journal_title：Cornea

authors： Toyama T,Honda N,Usui T,Amano S

更新日期：2014-04-01 00:00:00

abstract：PURPOSE:To investigate the times for an optimally secreting meibomian gland (OSMG) to be drained of available liquid secretion, to recover with expressible liquid secretion, and then to be redrained. METHODS:Twelve subjects with no dry eye symptoms and mean age 21.3 +/- 1.9 years were recruited. Lipid layer thickness ...

journal_title：Cornea

authors： Blackie CA,Korb DR

更新日期：2009-04-01 00:00:00

abstract：PURPOSE:To evaluate sleep and mood status in patients with dry eye disease (DED) and analyze the association between sleep quality, mood status, and ocular surface characteristics. METHODS:Consecutive patients with DED (N = 106) and age- and sex-matched healthy controls (N = 50) were enrolled. Tear fluid break up time...

journal_title：Cornea

authors： Wu M,Liu X,Han J,Shao T,Wang Y

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:To provide 6-month results of a 1-year clinical trial evaluating conductive keratoplasty (CK) for the treatment of presbyopic symptoms in emmetropic and hyperopic eyes. METHODS:A total of 143 patients with presbyopic symptoms were enrolled in this 1-year United States FDA clinical trial and treated to improve ...

journal_title：Cornea

authors： McDonald MB,Durrie D,Asbell P,Maloney R,Nichamin L

更新日期：2004-10-01 00:00:00

abstract：PURPOSE:To introduce an improved technique of pterygium surgery and to compare postoperative results between this technique and previous techniques. METHODS:In a retrospective survey, the records of 216 consecutive eyes with primary pterygium that underwent surgery by three different techniques were reviewed. The new ...

journal_title：Cornea

authors： Akura J,Kaneda S,Matsuura K,Setogawa A,Takeda K,Honda S

更新日期：2001-10-01 00:00:00

abstract：PURPOSE:To report intraocular lens (IOL) power calculation in 2 eyes that were highly undercorrected by previous myopic automated lamellar keratoplasty (ALK). METHODS:A 35-year-old man underwent bilateral myopic ALK, which caused high residual myopia (-9.0 -4.0 x 171 and -9.5 -4.5 x 74). The patient then underwent cat...

journal_title：Cornea

authors： Lee SH,Tsai CY,Liou SW,Tsai RJ,Ho JD

更新日期：2008-10-01 00:00:00

abstract：:This article reports the findings of investigations on an osteo-odonto-keratoprosthesis in an eye that was enucleated owing to severe complications 12 years after implantation. Scanning electron microscopy and electron probe X-ray microanalysis showed extensive resorption of the bone that was used as a supporting elem...

journal_title：Cornea

authors： Caiazza S,Falcinelli G,Pintucci S

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:To describe a novel use of conjunctival autograft in the management of surgically induced scleral necrosis that occurred after squint surgery. METHODS:Interventional case report. RESULTS:A 22-year-old man underwent bilateral adjustable squint surgery. Two weeks postoperatively, he developed conjunctival retra...

journal_title：Cornea

authors： Gregory ME,Weir CR,Ramaesh K

更新日期：2010-05-01 00:00:00