Treatment of presbyopia with conductive keratoplasty: six-month results of the 1-year United States FDA clinical trial.

Abstract:

PURPOSE:To provide 6-month results of a 1-year clinical trial evaluating conductive keratoplasty (CK) for the treatment of presbyopic symptoms in emmetropic and hyperopic eyes. METHODS:A total of 143 patients with presbyopic symptoms were enrolled in this 1-year United States FDA clinical trial and treated to improve near vision in 1 eye (unilateral treatment). In addition, 33 fellow eyes were treated to improve distance vision (bilateral treatment). For near vision correction, the target refraction was up to -2.0 D in the nondominant eye, and for distance vision correction, 0.0 D. Enrolled patients had a preoperative spherical equivalent of plano to +2.00 D, no more than 0.75 D of refractive astigmatism, and were 40 years of age or older. No retreatments were performed. RESULTS:Of the eyes treated for near, 77% had uncorrected near vision of J3 or better at 6 months postoperatively. A total of 85% of all patients had binocular distance UCVA of 20/25 or better along with J3 or better near, a combination that represents functional acuity for a presbyope. Sixty-six percent of eyes treated for near had a manifest refractive spherical equivalent (MRSE) within +/- 0.50 D of intended at 6 months. In 89% of eyes, the MRSE changed 0.05 D or less between 3 and 6 months postoperatively. After month 1, the incidence of variables associated with safety was 1% or lower. Seventy-six percent were very satisfied or satisfied with their procedure. CONCLUSIONS:CK appears to be very safe and effective in producing functional visual acuity in presbyopic eyes up to 6 months following the procedure. Patient satisfaction with the procedure is similar to that of monovision LASIK.

journal_name

Cornea

journal_title

Cornea

authors

McDonald MB,Durrie D,Asbell P,Maloney R,Nichamin L

doi

10.1097/01.ico.0000126321.13143.a0

subject

Has Abstract

pub_date

2004-10-01 00:00:00

pages

661-8

issue

7

eissn

0277-3740

issn

1536-4798

pii

00003226-200410000-00003

journal_volume

23

pub_type

临床试验,杂志文章,多中心研究

相关文献

CORNEA文献大全
  • In vivo confocal microscopic findings of two siblings with Maroteaux-Lamy syndrome.

    abstract:PURPOSE:To describe the clinical and in vivo confocal microscopic findings of the cornea in 2 male siblings with Maroteaux-Lamy syndrome. METHODS:Two male siblings 27 and 22 years of age who had been diagnosed with Maroteaux-Lamy syndrome underwent ophthalmologic assessment. In vivo confocal microscopy of their cornea...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31802be383

    authors: Mocan MC,Eldem B,Irkec M

    更新日期:2007-01-01 00:00:00

  • A Novel Epidemiological Approach to Geographically Mapping Population Dry Eye Disease in the United States Through Google Trends.

    abstract:PURPOSE:Our study fills the spatiotemporal gaps in dry eye disease (DED) epidemiology by using Google Trends as a novel epidemiological tool for geographically mapping DED in relation to environmental risk factors. METHODS:We used Google Trends to extract DED-related queries estimating users' intent from 2004 to 2019 ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002579

    authors: Azzam DB,Nag N,Tran J,Chen L,Visnagra K,Marshall K,Wade M

    更新日期:2020-11-06 00:00:00

  • Primary graft failure: a case control investigation of a purported cluster.

    abstract::Primary graft failure is a rare but major complication of penetrating keratoplasty. An apparent clustering of four cases during a 1-month period led to a review of all 778 keratoplasties performed by nine surgeons at Massachusetts Eye and Ear Infirmary from July 1, 1986 to June 30, 1988. The objectives of this study w...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199407000-00005

    authors: Mead MD,Hyman L,Grimson R,Schein OD

    更新日期:1994-07-01 00:00:00

  • Herpes simplex keratitis after intravitreal triamcinolone acetonide.

    abstract:PURPOSE:To report a case of recurrent herpes simplex virus (HSV) epithelial keratitis after intravitreal triamcinolone acetonide injection for the treatment of diabetic macular edema. METHODS:Case report. RESULTS:We describe a case of a 59-year-old woman with a history of ocular HSV disease and severe proliferative d...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318041f0c0

    authors: Shtein RM,Stahl RM,Saxe SJ,Mian SI

    更新日期:2007-06-01 00:00:00

  • Functional Morphology of the Lipid Layer of the Tear Film.

    abstract::Meibomian glands secrete the oily layer of the tear film, which prevents excessive evaporation of tear fluid. Dysfunction of meibomian glands is not only one of the causes of evaporative dry eye but also one of the main causes of entire dry eye. To understand the pathophysiology of meibomian gland dysfunction, it is i...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/ICO.0000000000001367

    authors: Arita R,Fukuoka S,Morishige N

    更新日期:2017-11-01 00:00:00

  • A novel approach to processing descemet stripping automated endothelial keratoplasty specimens for histopathologic analysis.

    abstract:PURPOSE:To describe a new technique for handling Descemet stripping automated endothelial keratoplasty (DSAEK) specimens intraoperatively and during processing. METHODS:The processing method begins by adding a drop of eosin to the specimen intraoperatively, followed by submersion in 10% formalin solution. The specimen...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181da57f3

    authors: Steven Houston SK,Morgan O,Olsakovsky LA,Phillips PM,Ghazi NG

    更新日期:2010-12-01 00:00:00

  • Descemet's stripping automated endothelial keratoplasty (DSAEK) using corneal donor tissue not acceptable for use in penetrating keratoplasty as a result of anterior stromal scars, pterygia, and previous corneal refractive surgical procedures.

    abstract:PURPOSE:The purpose of this study was to evaluate outcomes of Descemet's stripping automated endothelial keratoplasty (DSAEK) using anterior stromal flawed (ASF) donor corneas that were unsuitable for use in full-thickness penetrating keratoplasty as a result of stromal scars, pterygia, or previous corneal refractive s...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318199f8d7

    authors: Phillips PM,Terry MA,Shamie N,Chen ES,Hoar KL,Stoeger C,Friend DJ,Saad HA

    更新日期:2009-09-01 00:00:00

  • The corneal-thickness profile in Hong Kong Chinese.

    abstract:PURPOSE:This study investigated the topographic corneal thickness in four groups of Hong Kong Chinese. METHODS:The corneal thickness was determined with an ultrasound pachometer mounted on a X-Y plate. A head rest was used to reduce further any movement from the subject during the measurement. After the central cornea...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199807000-00008

    authors: Lam AK,Douthwaite WA

    更新日期:1998-07-01 00:00:00

  • Inhibitory effects of tranilast on the proliferation and functions of human pterygium-derived fibroblasts.

    abstract:PURPOSE:We studied the possibility that tranilast, an antiallergic and antiproliferative drug, may be beneficial for the treatment of pterygium. METHODS:Pterygium-derived cells were identified by immunohistochemical methods. Growth rate of pterygium-derived cells was determined by using a hemocytometer. Chemotaxis was...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200005000-00021

    authors: Isaji M,Kikuchi S,Miyata H,Ajisawa Y,Araki-Inazawa K,Tsukamoto Y,Amano Y

    更新日期:2000-05-01 00:00:00

  • Correlation Between Corneal Biomechanical Indices and the Severity of Keratoconus.

    abstract:PURPOSE:To investigate the correlations between the biomechanical indices determined in Scheimpflug-based corneal biomechanical assessments and the severity of keratoconus (KC) based on corneal tomographic assessments in patients with different stages of KC. METHODS:Fifty-three patients who presented with clinical KC ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002129

    authors: Koh S,Inoue R,Ambrósio R Jr,Maeda N,Miki A,Nishida K

    更新日期:2020-02-01 00:00:00

  • Donor tissue selection for anterior lamellar keratoplasty.

    abstract:PURPOSE:To assess the influence of donor characteristics on the outcome of anterior lamellar keratoplasty (ALK) and to evaluate whether corneal donor tissue considered unsuitable for penetrating or posterior lamellar keratoplasty due to poor endothelial condition may be safely used for ALK. METHODS:Institutional setti...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318285c8b4

    authors: Borderie VM,Sandali O,Basli E,Goldschmidt P,Laroche L

    更新日期:2013-08-01 00:00:00

  • Gene transfer using micellar nanovectors inhibits corneal neovascularization in vivo.

    abstract:PURPOSE:The efficacy of gene therapy using nonviral vector based on polyplex micelle has been studied against corneal neovascularization in mice. METHODS:A block copolymer, poly(ethylene glycol) (PEG)-block-polycation carrying ethylenediamine units in the side chain (PEG-b-P[Asp(DET)]), was prepared. PEG-b-P[Asp(DET)]...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318206c893

    authors: Iriyama A,Usui T,Yanagi Y,Amano S,Oba M,Miyata K,Nishiyama N,Kataoka K

    更新日期:2011-12-01 00:00:00

  • Healing rate of corneal erosions: comparison of the effect of chloramphenicol eye drops and ointment and high-concentration hyaluronic acid in an animal model.

    abstract:PURPOSE:The aim of this study was to compare the effect of chloramphenicol eye drops or ointment, high-concentration hyaluronic acid, or no treatment on reepithelialization of corneal erosions in an experimental model. METHODS:Uniform 6-mm corneal erosions were created in 23 rabbit eyes. The rabbits were randomized to...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000215

    authors: Barequet IS,Harizman N,Ziv H,Rosner M

    更新日期:2014-10-01 00:00:00

  • Fungal keratitis caused by Scedosporium apiospermum: report of two cases and review of treatment.

    abstract:PURPOSE:We report our experience in treating two cases of Scedosporium apiospermum keratitis and provide a review of basic scientific and clinical data regarding the treatment of this visually devastating disease. METHOD:We present a case report and literature review. RESULTS:A 35-year-old woman and a 73-year-old man...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/00003226-200207000-00016

    authors: Wu Z,Ying H,Yiu S,Irvine J,Smith R

    更新日期:2002-07-01 00:00:00

  • Comparison of corneal endothelial image analysis by Konan SP8000 noncontact and Bio-Optics Bambi systems.

    abstract:PURPOSE:Compare corneal endothelial image analysis by Konan SP8000 and Bio-Optics Bambi image-analysis systems. METHODS:Corneal endothelial images from 98 individuals (191 eyes), ranging in age from 4 to 87 years, with a normal slit-lamp examination and no history of ocular trauma, intraocular surgery, or intraocular ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Benetz BA,Diaconu E,Bowlin SJ,Oak SS,Laing RA,Lass JH

    更新日期:1999-01-01 00:00:00

  • Bilateral iridocorneal endothelial syndrome: case report and review of the literature.

    abstract::We present the case of a 47-year-old woman with bilateral iridocorneal endothelial syndrome. The iridocorneal endothelial syndrome has heretofore been considered a unilateral disorder. However, a review of the literature and examination of the patient presented in this report indicate that bilateral occurrence of the ...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/00003226-199407000-00015

    authors: Hemady RK,Patel A,Blum S,Nirankari VS

    更新日期:1994-07-01 00:00:00

  • Axenfeld's anomaly associated with Down's syndrome.

    abstract::We report a case of a patient with Down's syndrome and keratoconus with acute hydrops who was incidentally noted to have Axenfeld's anomaly. We also review the systemic abnormalities associated with Axenfeld's anomaly and the implications of the diagnosis. To our knowledge, Axenfeld's anomaly has not previously been r...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199203000-00012

    authors: Stokes DW,Parrish CM

    更新日期:1992-03-01 00:00:00

  • Grading of corneal and conjunctival staining in the context of other dry eye tests.

    abstract:PURPOSE:To describe the Oxford Scheme for grading ocular surface staining in dry eye and to discuss optimization of stain detection using various dyes and filters. Also, to propose a sequence of testing for dry eye diagnosis. METHODS:The grading of corneal and conjunctival staining is described, using the Oxford Schem...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/00003226-200310000-00008

    authors: Bron AJ,Evans VE,Smith JA

    更新日期:2003-10-01 00:00:00

  • Femtosecond Laser-Assisted Keratolimbal Allograft Transplantation for the Treatment of Total Limbal Stem Cell Deficiency.

    abstract:PURPOSE:To investigate the surgical procedure and therapeutic efficacy of femtosecond (FS) laser-assisted keratolimbal allograft (KLAL) transplantation in the treatment of eyes with total limbal stem cell deficiency. METHODS:Ten eyes from 10 patients who underwent FS laser-assisted KLAL transplantation were enrolled. ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002041

    authors: Qi X,Duan F,Li X,Zhang X,Li N,Liu M,Gao H

    更新日期:2019-10-01 00:00:00

  • Can we measure corneal biomechanical changes after collagen cross-linking in eyes with keratoconus?--a pilot study.

    abstract:PURPOSE:To assess changes in biomechanical properties of human cornea after treatment of keratoconus with UV-A-riboflavin corneal collagen cross-linking (CXL). DESIGN:Single-center, prospective, interventional study. METHODS:Ten eyes of 10 patients aged 26.5 +/- 5.7 (mean +/- SD) years with progressive keratoconus we...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318190734d

    authors: Goldich Y,Barkana Y,Morad Y,Hartstein M,Avni I,Zadok D

    更新日期:2009-06-01 00:00:00

  • Donor-related risk factors and preoperative recipient-related risk factors for graft failure.

    abstract:PURPOSE:The aim of this study was to evaluate the outcome of penetrating keratoplasties, at the University Eye Hospital, Ludwig-Maximilians-University, Munich, Germany, using organ-cultured donor corneas and to identify preoperative risk factors, which may influence the event of graft failure. METHODS:In this study, 3...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000225

    authors: Yu AL,Kaiser M,Schaumberger M,Messmer E,Kook D,Welge-Lussen U

    更新日期:2014-11-01 00:00:00

  • Clostridium sordellii endophthalmitis after suture removal from a corneal transplant.

    abstract:PURPOSE:To report a case of endophthalmitis caused by Clostridium sordellii. METHODS:A 33-year-old man sustained a penetrating injury of the right eye that resulted in several ocular surgical procedures including pars plana vitrectomy, scleral buckling, scleral-sutured posterior chamber intraocular lens, and penetrati...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000116528.57227.2f

    authors: Zink JM,Singh-Parikshak R,Sugar A,Johnson MW

    更新日期:2004-07-01 00:00:00

  • Vision-related impact on quality of life in an elderly patient population after corneal transplantation.

    abstract:PURPOSE:The aim of this study was to assess the vision-related quality of life (QOL) and satisfaction of elderly patients who underwent corneal transplantations. METHODS:Survey data using a modified version of the Visual Function Index were collected in February-March 2013 from 175 patients (age ≥65 years) of 414 elig...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000021

    authors: Puri S,Robinson SB,Wang J,Sikder S

    更新日期:2014-02-01 00:00:00

  • Eyelid Tattooing Induces Meibomian Gland Loss and Tear Film Instability.

    abstract:PURPOSE:To investigate the changes of meibomian gland (MG) and tear film stability in subjects with eyelid tattoos. METHODS:Forty female subjects were recruited. Ten subjects had eyelid tattoos and 30 subjects did not (control group). Tear film break-up time (TBUT) measurement and fluorescein staining were performed t...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000452

    authors: Lee YB,Kim JJ,Hyon JY,Wee WR,Shin YJ

    更新日期:2015-07-01 00:00:00

  • Fungal Interface Keratitis After Descemet Membrane Endothelial Keratoplasty.

    abstract:PURPOSE:To evaluate the incidence, clinical course, and management of fungal interface keratitis (IK) after Descemet membrane endothelial keratoplasty (DMEK). METHODS:This is a single-center retrospective observational case series of 3950 eyes undergoing DMEK. Six eyes with fungal IK were detected and analyzed. Analys...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001727

    authors: Augustin VA,Weller JM,Kruse FE,Tourtas T

    更新日期:2018-11-01 00:00:00

  • In vitro amoebicidal activity of propamidine and pentamidine isethionate against Acanthamoeba species and toxicity to corneal tissues.

    abstract::Effective chemotherapy for Acanthamoeba keratitis has been hampered because of the marked resistance of the parasites to a variety of antimicrobial agents. In view of the fact that topical Brolene (propamidine isethionate) and neosporin are currently considered to be the medical treatment of choice in Europe, we sough...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Alizadeh H,Silvany RE,Meyer DR,Dougherty JM,McCulley JP

    更新日期:1997-01-01 00:00:00

  • Topical anesthetic abuse ring keratitis: report of four cases.

    abstract:PURPOSE:We present the clinicopathologic correlations of two case and two other clinical cases of topical anesthetic abuse keratopathy that were originally diagnosed as Acanthamoeba keratitis because of ring keratitis presentation and characteristic history. METHODS:Four patients who were referred to us with suspected...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Varga JH,Rubinfeld RS,Wolf TC,Stutzman RD,Peele KA,Clifford WS,Madigan W

    更新日期:1997-07-01 00:00:00

  • MT1-MMP cleavage of the antiangiogenic proteoglycan decorin: role in corneal angiogenesis.

    abstract:PURPOSE:Decorin is a small chondroitin sulfate proteoglycan that inhibits vascular endothelial cell migration and tube formation. Membrane type 1-matrix metalloproteinase (MT1-MMP) has been shown to be an important angiogenic enzyme in the cornea. We evaluated the specific role of MT1-MMP in decorin cleavage in the cor...

    journal_title:Cornea

    pub_type: 杂志文章,收录出版

    doi:10.1097/ICO.0b013e31822816e0

    authors: Mimura T,Chang JH,Kim TI,Onguchi T,Kojima T,Sakimoto T,Azar DT

    更新日期:2011-10-01 00:00:00

  • Corneal transplant rejection rate and severity after endothelial keratoplasty.

    abstract:PURPOSE:To examine the corneal transplant rejection rate and the rate of graft failure subsequent to rejection in the first 2 years after endothelial keratoplasty (EK) and to compare this to background data for similar cases of penetrating keratoplasty (PK). METHODS:Anonymized data from consecutive cases of EK [deep l...

    journal_title:Cornea

    pub_type: 杂志文章,多中心研究

    doi:10.1097/ICO.0b013e31812f66e5

    authors: Allan BD,Terry MA,Price FW Jr,Price MO,Griffin NB,Claesson M

    更新日期:2007-10-01 00:00:00

  • Donor factors associated with epithelial defects after penetrating keratoplasty.

    abstract::The records of 39 patients undergoing 40 consecutive penetrating keratoplasties were reviewed to identify donor factors that might correlate with the presence of an epithelial defect on the first postoperative day. Of the 40 transplanted corneas, 13 (32.5%) had no epithelial defect, 18 (45%) had some epithelial defect...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Kim T,Palay DA,Lynn M

    更新日期:1996-09-01 00:00:00