Abstract:
PURPOSE:To investigate the times for an optimally secreting meibomian gland (OSMG) to be drained of available liquid secretion, to recover with expressible liquid secretion, and then to be redrained. METHODS:Twelve subjects with no dry eye symptoms and mean age 21.3 +/- 1.9 years were recruited. Lipid layer thickness and tear breakup time were measured. The number of meibomian glands yielding liquid secretion for both right and left lower eyelids was counted using a meibomian gland diagnostic expression device. A single OSMG in the central third of the right and left lower eyelids was marked. A second diagnostic expression device was used to drain the liquid secretion from each marked gland. The times to drain the gland of available liquid secretion, for the drained gland to recover, and then be redrained were measured. RESULTS:The mean lipid layer thickness and tear breakup time were 98 +/- 44 nm and 12.4 +/- 1.9 seconds. The mean time to drain the marked meibomian gland was 12.1 +/- 3.5 seconds, range: 8-20 seconds; for partial recovery of the drained meibomian gland was 2.17 +/- 0.49 hours, range: 1.5-2.5 hours; and to redrain the meibomian gland after recovery was 5.54 +/- 1.9 seconds, range: 5-10 seconds. CONCLUSIONS:This report shows that (1) a single OSMG can be drained of its liquid secretion in 8-20 seconds upon application of a constant force of 1 g/mm, and (2) a partial recovery occurs after approximately 2 hours, evidenced by detectable liquid secretion which then expressed for only half of the original time.
journal_name
Corneajournal_title
Corneaauthors
Blackie CA,Korb DRdoi
10.1097/ICO.0b013e31818913b4subject
Has Abstractpub_date
2009-04-01 00:00:00pages
293-7issue
3eissn
0277-3740issn
1536-4798pii
00003226-200904000-00008journal_volume
28pub_type
杂志文章相关文献
CORNEA文献大全abstract:PURPOSE:To report a case of partial limbal stem cell deficiency (LSCD) caused by epidermolysis bullosa dystrophica mutilans Hallopeau-Siemens treated by transplantation of autologous ex vivo expanded limbal epithelium. METHODS:Review of the clinical findings of an 11.5-year-old boy with unilateral LSCD and epidermolys...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181b442ea
更新日期:2010-04-01 00:00:00
abstract:PURPOSE:To investigate corneal stiffness and analyze its possible influence on other corneal biomechanical and nonbiomechanical parameters in myopic eyes of Chinese patients. METHODS:A total of 387 healthy (right) myopic eyes were included in this study. Corneal visualization Scheimpflug technology was used to measure...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001605
更新日期:2018-07-01 00:00:00
abstract:PURPOSE:To estimate the prevalence of meibomian gland dysfunction (MGD) in the Japanese population using new diagnostic criteria, including lid margin abnormalities and signs of occlusion of the meibomian gland orifices as essential signs. METHODS:The participants were consecutive patients scheduled for cataract surge...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001208
更新日期:2017-06-01 00:00:00
abstract:PURPOSE:This study was designed to report a case of biopsy-proven mucous membrane pemphigoid with severe bronchial involvement in a young woman. METHODS:Case report of a 17-year-old girl who presented with worsening dyspnea, skin rash, and bilateral ocular injection, symblepharon, and fornix foreshortening. Conjunctiv...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000178730.34564.c7
更新日期:2006-05-01 00:00:00
abstract:PURPOSE:To study dry eye and analyze pathogenic factors in patients after cataract surgery. METHODS:A total of 37 patients (50 eyes) were studied by using a 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ25) and Ocular Surface Disease Index (OSDI) 3 days before and 1 week, 1 month, and 3 months a...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31812f67ca
更新日期:2007-10-01 00:00:00
abstract:PURPOSE:The purpose of this study was to evaluate outcomes of Descemet's stripping automated endothelial keratoplasty (DSAEK) using anterior stromal flawed (ASF) donor corneas that were unsuitable for use in full-thickness penetrating keratoplasty as a result of stromal scars, pterygia, or previous corneal refractive s...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318199f8d7
更新日期:2009-09-01 00:00:00
abstract::Eight pseudomonal species were involved in 106 invasive infections of the eye; all were community acquired. Eighteen percent of the total and 9% of the Pseudomonas aeruginosa strains were gentamicin resistant, as defined using conventional criteria. All 10 cases of "resistant" pseudomonal (nine P. aeruginosa) keratiti...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1989-09-01 00:00:00
abstract:PURPOSE:To report intraoperative and 1-year postoperative results of the pachy-bubble technique for deep anterior lamellar keratoplasty (DALK). METHODS:This prospective interventional case series included 110 eyes of 107 patients with anterior corneal pathology who underwent DALK, including 78 with keratoconus. Outcom...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000413
更新日期:2015-06-01 00:00:00
abstract::Contact lens (CL) fitting carries the risk of transmitting infectious agents, including adenovirus and Pseudomonas. Therefore, a number of precautions must be observed to ensure safety in the office. Paramount among these is hand washing, both immediately after contact with a patient's eyes and again between patients....
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/00003226-199010001-00017
更新日期:1990-01-01 00:00:00
abstract:PURPOSE:To measure subbasal nerve density and orientation in normal human corneas across a broad age range. METHODS:Sixty-five normal corneas of 65 subjects were examined by using tandem scanning confocal microscopy. Ages of subjects ranged from 15 to 79 years (mean 46 +/- 19 years), with 5 subjects from each hemideca...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000154387.51355.39
更新日期:2005-08-01 00:00:00
abstract:PURPOSE:To study the corneal biocompatibility of bevacizumab on various cultured human corneal cells. METHODS:Cell cultures of corneal keratinocytes (CKs), corneal fibroblasts (CFs), and corneal endothelial cells (CECs) were harvested from human donor eyes and exposed to various concentrations of bevacizumab (0.25-5.0...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3180de1d0a
更新日期:2007-09-01 00:00:00
abstract:PURPOSE:To assess the effects of corneal collagen cross-linking (CXL) on contrast sensitivity (CS), visual acuity, and corneal topography investigating possible predictors of efficacy. METHODS:Sixty-eight eyes of 34 patients with progressive keratoconus were enrolled in this prospective study. CXL was performed in one...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31826672e2
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:To describe severe acute corneal hydrops in a patient with previously undiagnosed keratoconus, in which anterior segment optical coherence tomography (AS-OCT) revealed a protruding ridge of tissue on either side of Descemet membrane (DM) break, treated successfully with ultrathin Descemet-stripping automated en...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002464
更新日期:2020-09-09 00:00:00
abstract:PURPOSE:The aim of this study was to determine the effect of nicergoline in patients with neurotrophic keratopathy. METHODS:This is a prospective, noncomparative interventional study. The study included 27 eyes of 24 patients with neurotrophic keratopathy who were unresponsive to conventional therapy. Patients were tr...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000348
更新日期:2015-03-01 00:00:00
abstract:PURPOSE:To determine the relationships among endothelial morphometric variables and contact lens-induced corneal swelling in a homogeneous sample of adapted contact-lens wearers. METHODS:Fifteen male subjects ranging in age from 20 to 40 years, all adapted to daily wear of hydrogel lenses, wore uniform-thickness lense...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199803000-00006
更新日期:1998-03-01 00:00:00
abstract:PURPOSE:The aim was to assess the clinical outcomes of corneal graft infections caused by multi-drug resistant Pseudomonas aeruginosa (MDR-PA). METHODS:This is a retrospective case series of 38 patients with corneal graft infections caused by MDR-PA managed from June to December 2011. Clinical and demographic details,...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000011
更新日期:2014-01-01 00:00:00
abstract::There have been reports of the clearing of sclera that has been grafted into the cornea. This clearing was studied in the rabbit by transplanting full-thickness scleral buttons or by implanting slivers of sclera, both autografts and allografts, into the cornea. Some clearing around the edges of the implanted scleral t...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199603000-00015
更新日期:1996-03-01 00:00:00
abstract:PURPOSE:In a Strampelli osteo-odonto-keratoprosthesis, a patch of oral mucosa is frequently used to cover the ocular surface after implantation of an osteodental lamina into the eye. In many cases, gross modifications in the eye covering become apparent a few years later. The aim of this study was to investigate the hi...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000170695.98078.42
更新日期:2006-02-01 00:00:00
abstract:PURPOSE:We report two patients with primary graft failure (PGF) from a mutual donor. The surgery in each case was done by a different surgeon experienced in penetrating keratoplasty (PK). The cases were managed differently in the postoperative period with good visual results in both cases. We discuss the various manage...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199803000-00016
更新日期:1998-03-01 00:00:00
abstract:PURPOSE:The purpose of this report was to describe an uncommon wavelike epitheliopathy after phacoemulsification in a 59-year-old man with well-controlled diabetes mellitus. METHODS:Retrospective case report. RESULTS:A 59-year-old man with a history of well-controlled diabetes mellitus presented to us with irritation...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31804f59f3
更新日期:2007-07-01 00:00:00
abstract:PURPOSE:To assess ultrastructural modifications in keratocytes and inflammatory cell response in rabbit corneas after riboflavin and ultraviolet A exposure using immunofluorescence microscopy. METHODS:Twenty adult New Zealand albino rabbits weighing 2.0–3.0 kg were used in this study. Two rabbits served as controls.Th...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181bdf1cc
更新日期:2010-04-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the psychometric properties of the Keratoconus Outcomes Research Questionnaire (KORQ) in patients enrolled in the Save Sight Keratoconus Registry. METHODS:A cross-sectional study was conducted utilizing prospectively collected web-based registry data. The psychometric prop...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002169
更新日期:2020-03-01 00:00:00
abstract::Endothelial keratoplasty has revolutionized the treatment of corneal endothelial dysfunction and lowered the threshold for treatment by providing rapid visual rehabilitation and setting a high standard for safety and efficacy. Over time, endothelial keratoplasty techniques have evolved toward the use of thinner tissue...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002565
更新日期:2020-11-30 00:00:00
abstract:PURPOSE:To describe two cases of secondary congenital aphakia in association with Peters anomaly. METHODS:Two infants were noted to have corneal opacification at birth. Each child was found to have Peters anomaly requiring corneal transplantation in 1 or both eyes. RESULTS:Each child underwent penetrating keratoplast...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000134187.19117.6a
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To report on the safety and clinical use of combined subconjunctival and intracorneal bevacizumab for corneal neovascularization. METHODS:The charts of 12 consecutive patients with corneal neovascularization who received combined subconjunctival and intracorneal injections of bevacizumab (2.5 mg/0.1 mL) were r...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31821379aa
更新日期:2011-10-01 00:00:00
abstract:PURPOSE:To confirm the ocular tropism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by evaluating the expression of viral entry factors in human ocular tissues using immunohistochemistry. METHODS:Fresh donor corneas and primary explant cultures of corneal, limbal, and conjunctival epithelial cells we...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002509
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:To compare the process of conjunctival epithelial regeneration after three types of pterygium excision procedures. METHODS:Thirty-eight patients (45 eyes) with primary pterygium were randomly assigned to a bare-sclera procedure (group 1, 15 eyes of 12 patients), bare-sclera with intraoperative mitomycin C (MMC...
journal_title:Cornea
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00003226-200104000-00002
更新日期:2001-04-01 00:00:00
abstract::To evaluate an innovative technique for intrastromal air injection to achieve deep anterior lamellar keratoplasty (DALK) with bare Descemet membrane (DM). Thirty-four eyes with anterior corneal pathology, including 27 with keratoconus, underwent DALK. After 400 μm trephination with a suction trephine, ultrasound pachy...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31823f8f2d
更新日期:2012-09-01 00:00:00
abstract::We present two cases of posterior amorphous corneal dystrophy in members of the same family. We correlated the clinical findings with refraction, topography, and ultrasound biomicroscopy (UBM). This is the first report of UBM findings in amorphous corneal dystrophy and we describe the depth of stromal opacification me...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200203000-00020
更新日期:2002-03-01 00:00:00
abstract:PURPOSE:To evaluate the morphological features of the corneal limbus as measured by in vivo confocal microscopy (IVCM) following standard and accelerated corneal collagen cross-linking (CXL) for keratoconus. METHODS:Patients with progressive keratoconus scheduled to undergo standard CXL (group 1; 31 patients, 3 mW/cm,...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001029
更新日期:2017-01-01 00:00:00