Excision of granulation tissue and free conjunctival autograft in the management of necrotizing scleritis.

Abstract:

PURPOSE:To describe a novel use of conjunctival autograft in the management of surgically induced scleral necrosis that occurred after squint surgery. METHODS:Interventional case report. RESULTS:A 22-year-old man underwent bilateral adjustable squint surgery. Two weeks postoperatively, he developed conjunctival retraction and an area of scleral necrosis/melting with 80% thinning. The surrounding conjunctiva was markedly inflamed with raised edges. Screening for autoimmune and vasculitic conditions did not provide any positive results. The conjunctiva surrounding the area of scleral melt was excised and the area covered by a conjunctival autograft resulting in complete healing of the scleral melt within 1 month of surgery. CONCLUSION:The pathogenesis of surgically induced scleral necrosis not associated with autoimmune conditions may be the result of the products of inflammation and lytic enzymes released by the surrounding conjunctival tissue initiating the scleral melting process. This type of surgically induced scleral necrosis may be successfully managed by excision of the surrounding inflamed conjunctiva, thus removing a potential source of collagenases, and covering the exposed sclera by a conjunctival transplant obviating the need for prolonged high-dose immunosuppression.

journal_name

Cornea

journal_title

Cornea

authors

Gregory ME,Weir CR,Ramaesh K

doi

10.1097/ICO.0b013e3181b532e5

subject

Has Abstract

pub_date

2010-05-01 00:00:00

pages

577-9

issue

5

eissn

0277-3740

issn

1536-4798

journal_volume

29

pub_type

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