Microcomputer software applied to corneal stromal biometry.

Abstract:

:Here we report a new method for image analysis of the corneal stroma. To obtain the biometric characteristics of a given area, we perform three different treatments of the same image. These automated predictions closely match each parameter (length, surface area, etc.), as measured manually by a "blind investigator." Furthermore, to obtain quantifiable, average values, we have increased the number of successive image measurements, which has led to the development of a series of programs designed to optimize automated data handling. Finally, the acquired, calculated parameters are summarized in the form of intermediate tables for each series of images, and as a final summary table incorporating t-test values and permitting comparison between two stromas (e.g., normal and pathological). Multivariate analysis and an ascending hierarchical classification demonstrate the main trends in differences of pathological vs. normal stroma.

journal_name

Cornea

journal_title

Cornea

authors

Karpouzas I,Durand JP,Keller N,Savoldelli M,Pouliquen Y

doi

10.1097/00003226-199107000-00009

subject

Has Abstract

pub_date

1991-07-01 00:00:00

pages

330-40

issue

4

eissn

0277-3740

issn

1536-4798

journal_volume

10

pub_type

杂志文章

相关文献

CORNEA文献大全
  • Culturing Discarded Peripheral Human Corneal Endothelial Cells From the Tissues Deemed for Preloaded DMEK Transplants.

    abstract:PURPOSE:To investigate if the peripheral corneal endothelium that is discarded after the preparation of preloaded Descemet membrane endothelial keratoplasty (DMEK) grafts for transplantation could be successfully used for corneal endothelial cell culture. METHODS:Complete Descemet membrane-endothelial complex (11.00 m...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001998

    authors: Parekh M,Romano V,Ruzza A,Kaye SB,Ponzin D,Ahmad S,Ferrari S

    更新日期:2019-09-01 00:00:00

  • A novel technique for performing full-bed deep lamellar keratoplasty.

    abstract::In recent years, deep lamellar keratoplasty (DLKP) has become an alternative surgical approach successfully applied to the treatment of opaque cornea with normal endothelial function. However, techniques for performing DLKP are not standardized and have not been perfected compared with penetrating keratoplasty. We dev...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31817f445f

    authors: Yao YF

    更新日期:2008-09-01 00:00:00

  • Comparative Evaluation of Central Corneal Thickness in Cross-Linked Keratoconic Eyes.

    abstract:PURPOSE:To compare the central corneal thickness (CCT) measurements measured by using the Pentacam Scheimpflug system with the CCT measured using ultrasound pachymetry (UP) and to compare the compatibility between the methods in normal, keratoconic, and cross-linked keratoconic corneas. METHODS:The study included 50 e...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002339

    authors: Kosekahya P,Koc M,Yalcinsoy KO,Kocabas DO,Toker MI

    更新日期:2020-09-01 00:00:00

  • Posterior polymorphous dystrophy associated with nonkeratoconic steep corneal curvatures.

    abstract:PURPOSE:To report a case series of eyes with posterior polymorphous corneal dystrophy and steep nonkeratoconic corneas. METHODS:Retrospective, descriptive, nonrandomized case series. RESULTS:Thirty-five eyes of 18 patients (14 cases from 6 families and 4 isolated cases) with diffuse posterior polymorphous corneal dys...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3182114452

    authors: Raber IM,Fintelmann R,Chhabra S,Ribeiro MP,Eagle RC Jr,Orlin SE

    更新日期:2011-10-01 00:00:00

  • Incidence and prevalence of glaucoma in severe ocular surface disease.

    abstract:PURPOSE:To describe the incidence and prevalence of glaucoma in a patient population with severe ocular surface disease (OSD). METHODS:A retrospective case series was compiled from all charts of patients in the Cincinnati Eye Institute/University of Cincinnati and University of Minnesota population with a diagnosis of...

    journal_title:Cornea

    pub_type: 杂志文章,多中心研究

    doi:10.1097/01.ico.0000220776.93852.d9

    authors: Tsai JH,Derby E,Holland EJ,Khatana AK

    更新日期:2006-06-01 00:00:00

  • Management of Descemet Membrane Detachment After Forceps Birth Injury.

    abstract:PURPOSE:To describe the clinical signs of Descemet membrane (DM) detachment due to forceps-related birth injury and its subsequent management using optical coherence tomography. METHODS:Case report. RESULTS:A 3-day-old term infant presented with left eye corneal clouding and a definitive history of traumatic forceps-...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001147

    authors: Kancherla S,Shue A,Pathan MF,Sylvester CL,Nischal KK

    更新日期:2017-03-01 00:00:00

  • The intraoperative use of mitomycin-C in excision of ocular surface neoplasia with or without limbal autograft transplantation.

    abstract:PURPOSE:To evaluate the efficacy of intraoperative mitomycin-C in excision of ocular surface neoplasia for prevention of recurrence. METHODS:Seven patients (eight eyes), three men and four women, aged 56 to 87 years (mean, 73.8 years), with lesions suspicious for corneal or conjunctival neoplasia, were operated on bet...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200201000-00004

    authors: Siganos CS,Kozobolis VP,Christodoulakis EV

    更新日期:2002-01-01 00:00:00

  • Effects of Repeated Intravitreal Aflibercept Injection on the Corneal Endothelium in Patients With Age-Related Macular Degeneration: Outcomes From the RE-VIEW Study.

    abstract:PURPOSE:The effects of repeated intravitreal aflibercept injection (IAI) on the corneal endothelium were studied in patients with unilateral neovascular age-related macular degeneration. METHODS:RE-VIEW was a phase 4, open-label, single-arm, multicenter study. Patients received IAI every 8 weeks after 3 monthly doses....

    journal_title:Cornea

    pub_type: 杂志文章,多中心研究

    doi:10.1097/ICO.0000000000001535

    authors: Lass JH,Benetz BA,Menegay HJ,Tsipis CP,Cook JC,Boyer DS,Singer M,Erickson K,Saroj N,Vitti R,Chu KW,Moini H,Soo Y,Cheng Y

    更新日期:2018-05-01 00:00:00

  • Confocal Microscopic Analysis of a Rabbit Eye Model of High-Incidence Recurrent Herpes Stromal Keratitis.

    abstract:PURPOSE:Using CJLAT, a chimeric herpes simplex virus (HSV-1) that produces a high incidence of herpes stromal keratitis (HSK) in latently infected rabbits, and in vivo confocal microscopy (CM), we characterized the cellular events that precede the development of HSK. METHODS:Thirty days after infection, in vivo CM was...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000666

    authors: Jester JV,Morishige N,BenMohamed L,Brown DJ,Osorio N,Hsiang C,Perng GC,Jones C,Wechsler SL

    更新日期:2016-01-01 00:00:00

  • Treatment of neurotrophic keratopathy with nicergoline.

    abstract:PURPOSE:The aim of this study was to determine the effect of nicergoline in patients with neurotrophic keratopathy. METHODS:This is a prospective, noncomparative interventional study. The study included 27 eyes of 24 patients with neurotrophic keratopathy who were unresponsive to conventional therapy. Patients were tr...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000348

    authors: Lee YC,Kim SY

    更新日期:2015-03-01 00:00:00

  • Long-term outcome in high-risk corneal transplantation and the influence of HLA-A and HLA-B matching.

    abstract:PURPOSE:To evaluate long-term follow-up of high-risk corneal transplants allocated after matching for broad HLA-A and HLA-B antigens and to establish whether matching for HLA-A and -B antigen "splits" would result in a reduced risk of immunologic graft failure. METHODS:A total of 303 high risk corneal transplants was ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200308000-00013

    authors: Bartels MC,Doxiadis II,Colen TP,Beekhuis WH

    更新日期:2003-08-01 00:00:00

  • Topographic patterns in refractive surgery candidates.

    abstract:PURPOSE:To evaluate the prevalence of different topographic patterns in refractive surgery candidates and to estimate the extent of candidate rejection based on topography alone. METHODS:We performed a retrospective evaluation of videokeratographies of previously unoperated refractive surgery candidates. The defined t...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000121699.74077.f0

    authors: Varssano D,Kaiserman I,Hazarbassanov R

    更新日期:2004-08-01 00:00:00

  • Ocular manifestations after primary varicella infection.

    abstract:PURPOSE:To report a case of ocular manifestations after a primary varicella infection. METHODS:Review of the literature and a case report of a 10-year-old male patient with history of blurry vision and an enlarged pupil 2 months after a varicella infection. Examination revealed uveitis, interstitial keratitis, and int...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000224651.19837.6c

    authors: Fernández de Castro LE,Sarraf OA,Hawthorne KM,Solomon KD,Vroman DT

    更新日期:2006-08-01 00:00:00

  • Tear Matrix Metalloproteinases and Myeloperoxidase Levels in Patients With Boston Keratoprosthesis Type I.

    abstract:PURPOSE:To investigate the tear levels of matrix metalloproteinases (MMPs), myeloperoxidase (MPO), and tissue inhibitor of metalloproteinase-1 in eyes after Boston keratoprosthesis type I (B-KPro) implantation and to correlate these markers with the established B-KPro prognostic categories. METHODS:Tear washes were co...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000893

    authors: Robert MC,Arafat SN,Spurr-Michaud S,Chodosh J,Dohlman CH,Gipson IK

    更新日期:2016-07-01 00:00:00

  • Association Between Sleep Quality, Mood Status, and Ocular Surface Characteristics in Patients With Dry Eye Disease.

    abstract:PURPOSE:To evaluate sleep and mood status in patients with dry eye disease (DED) and analyze the association between sleep quality, mood status, and ocular surface characteristics. METHODS:Consecutive patients with DED (N = 106) and age- and sex-matched healthy controls (N = 50) were enrolled. Tear fluid break up time...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001854

    authors: Wu M,Liu X,Han J,Shao T,Wang Y

    更新日期:2019-03-01 00:00:00

  • Onset of ocular graft-versus-host disease symptoms after allogeneic hematopoietic stem cell transplantation.

    abstract:OBJECTIVE:To study the factors affecting the time to onset of ocular graft-versus-host disease (GVHD) in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). METHODS:A retrospective chart review of 200 patients with ocular GVHD was performed to evaluate the association between various do...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000340

    authors: Shikari H,Amparo F,Saboo U,Dana R

    更新日期:2015-03-01 00:00:00

  • Prevalence of positive microbiology results from donor cornea tissue in different methods of corneal transplantation.

    abstract:PURPOSE:To evaluate the prevalence of positive microbiology results (culture and/or Gram stain) in donor cornea tissue with newer transplant methods and to assess if the results subsequently correlate with higher incidence of clinical infection. METHODS:A retrospective review of the microbiology records of 569 consecu...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3182542368

    authors: Garg S,Said B,Farid M,Steinert RF

    更新日期:2013-02-01 00:00:00

  • Ocular penetration and pharmacokinetics of topical gatifloxacin 0.3% and moxifloxacin 0.5% ophthalmic solutions after keratoplasty.

    abstract:PURPOSE:To compare the corneal and aqueous penetration and pharmacokinetics of gatifloxacin 0.3% and moxifloxacin 0.5% ophthalmic solutions and their effect on corneal reepithelialization after penetrating keratoplasty. METHODS:In this randomized, open-label, parallel-controlled study, corneal and aqueous penetration ...

    journal_title:Cornea

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/ICO.0b013e3181608561

    authors: Holland EJ,Lane SS,Kim T,Raizman M,Dunn S

    更新日期:2008-04-01 00:00:00

  • Assessment of keratocyte density in patients with keratoconus not using contact lenses.

    abstract:PURPOSE:To assess the keratocyte density (KD) in the cornea of patients with keratoconus not using contact lenses. METHOD:In this pilot study, the eyes (n = 68) of 35 patients with the diagnosis of keratoconus, who did not use contact lenses and the eyes(n = 70) of 35 healthy controls were prospectively examined using...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3182000fd4

    authors: Timucin OB,Karadag MF,Cinal A

    更新日期:2011-05-01 00:00:00

  • New graft inserter for descemet stripping automated endothelial keratoplasty.

    abstract:PURPOSE:The aim of this study was to introduce a newly developed graft inserter for Descemet stripping automated endothelial keratoplasty, which can be readily used with 1 hand, and to examine endothelial cell loss (ECL) after graft insertion using this new inserter in an ex vivo rabbit model. METHODS:Rabbit corneal g...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000073

    authors: Toyama T,Honda N,Usui T,Amano S

    更新日期:2014-04-01 00:00:00

  • A case of infectious crystalline keratopathy occurring long after penetrating keratoplasty.

    abstract:PURPOSE:To report a 64-year-old woman's case of infectious crystalline keratopathy (ICK) that occurred 9 years after the penetrating keratoplasty (PKP). METHODS:This study includes clinical history and histopathologic findings of the case. RESULTS:As historic background, the patient underwent PKP for lattice dystroph...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199801000-00018

    authors: Matsumoto A,Sano Y,Nishida K,Yokoi N,Hara J,Kinoshita S

    更新日期:1998-01-01 00:00:00

  • Visual Function and Higher-Order Aberrations in Eyes After Corneal Transplantation: How to Improve Postoperative Quality of Vision.

    abstract::An understanding of corneal optics is important to optimize the visual outcome after eye surgery. Recent advances in the surgical techniques of lamellar keratoplasty have changed the strategies used for corneal transplantation. Lamellar keratoplasty has the advantage of having a lower rate of graft rejection, superior...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/ICO.0000000000000589

    authors: Yamaguchi T,Satake Y,Dogru M,Ohnuma K,Negishi K,Shimazaki J

    更新日期:2015-11-01 00:00:00

  • Preliminary in vitro evaluation of 2-octyl cyanoacrylate (Dermabond) to seal corneal incisions.

    abstract:OBJECTIVE:To compare the efficacy of Dermabond with conventional nylon sutures for sealing linear corneal incisions. METHODS:A keratome knife was used to create a 4-mm full-thickness linear corneal incision anterior to the limbal arcade in 20 fresh pig eyes. The incision was sealed with Dermabond tissue adhesive or cl...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000159734.75672.c4

    authors: Leung GY,Peponis V,Varnell ED,Lam DS,Kaufman HE

    更新日期:2005-11-01 00:00:00

  • Characterization of Corneal Donor Tissue Lesions by Anterior Segment Optical Coherence Tomography Compared With Eye Bank Technician Slit-Lamp Examination.

    abstract:PURPOSE:To compare anterior segment spectral-domain optical coherence tomography (OCT) with eye bank technician slit-lamp examination (SLE) in characterizing lesions in donor corneas. METHODS:Twenty-nine donor corneas identified by eye bank technicians to have opacities or lesions potentially representing pathologic f...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001700

    authors: Hsu ST,Perry I,Botsay S,Ko N,Stinnett SS,Kuo AN,Shieh C

    更新日期:2018-10-01 00:00:00

  • The histopathology of the iridocorneal-endothelial syndrome.

    abstract::The iridocorneal-endothelial (ICE) syndrome is characterised clinically by a "hammered-silver" appearance of the corneal endothelium, corneal failure, glaucoma, and iris destruction. Specular photomicroscopic studies of the corneal endothelium have demonstrated a population of abnormal cells termed "ICE cells." The pu...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Levy SG,Kirkness CM,Moss J,Ficker L,McCartney AC

    更新日期:1996-01-01 00:00:00

  • Diagnosis of Aspergillus keratitis in vivo with confocal microscopy.

    abstract::Confocal microscopy provides a new, noninvasive way of imaging the human cornea in vivo. One of its most important clinical uses is the diagnosis and management of infectious keratitis. The authors used tandem scanning confocal microscopy to image the corneas in two culture-proven cases of Aspergillus keratitis. Funga...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Winchester K,Mathers WD,Sutphin JE

    更新日期:1997-01-01 00:00:00

  • Clinicopathologic correlation of textural interface opacities in descemet stripping automated endothelial keratoplasty: a case study.

    abstract:PURPOSE:The aim of this study was to describe the clinicopathologic correlation of textural interface opacities (TIOs) in a Descemet stripping automated endothelial keratoplasty (DSAEK) donor button after its removal. METHODS:A 75-year-old woman underwent combined phacoemulsification with intraocular lens placement an...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000057

    authors: Newman LR,Rosenwasser GO,Dubovy SR,Matthews JL

    更新日期:2014-03-01 00:00:00

  • Cyclosporine A Downregulates MMP-3 and MMP-13 Expression in Cultured Pterygium Fibroblasts.

    abstract:PURPOSE:To investigate the regulation of matrix metalloproteinase (MMP)-3 and MMP-13 expression over time and in the presence of cyclosporine A (CsA) in primary cultured human pterygium fibroblasts. We also examined the effects of CsA on cultured human pterygium fibroblasts. METHODS:Primary cultured human pterygium fi...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000477

    authors: Kim YH,Jung JC,Jung SY,Kim YI,Lee KW,Park YJ

    更新日期:2015-09-01 00:00:00

  • Long-term corneal clarity after spontaneous repair of an iatrogenic descemetorhexis in a patient with Fuchs dystrophy.

    abstract:PURPOSE:To report a case of long-term corneal clarity after spontaneous resolution of corneal edema associated with iatrogenic endothelial trauma in a patient with Fuchs dystrophy. METHODS:Retrospective case report. RESULTS:An 84-year-old woman with Fuchs dystrophy experienced an iatrogenic descemetorhexis during com...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3182886aaa

    authors: Koenig SB

    更新日期:2013-06-01 00:00:00

  • Treatment of Acute Corneal Hydrops With Combined Intracameral Gas and Approximation Sutures in Patients With Corneal Ectasia.

    abstract:PURPOSE:To assess the efficacy and safety of combined intracameral sulfur hexafluoride and full-thickness corneal sutures in the treatment of acute corneal hydrops (CH). METHODS:This is an uncontrolled series of cases with keratoconus (KC), keratoglobus (KG), and pellucid marginal degeneration that presented with CH o...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002155

    authors: Mohebbi M,Pilafkan H,Nabavi A,Mirghorbani M,Naderan M

    更新日期:2020-02-01 00:00:00