Abstract:
:Confocal microscopy provides a new, noninvasive way of imaging the human cornea in vivo. One of its most important clinical uses is the diagnosis and management of infectious keratitis. The authors used tandem scanning confocal microscopy to image the corneas in two culture-proven cases of Aspergillus keratitis. Fungal hyphae were imaged as high-contrast filaments 6 microns in diameter from 60 to 400 microns in length. Confocal microscopy may be a fast and safe diagnostic tool in determining the presence of fungal hyphae in vivo within the human cornea.
journal_name
Corneajournal_title
Corneaauthors
Winchester K,Mathers WD,Sutphin JEsubject
Has Abstractpub_date
1997-01-01 00:00:00pages
27-31issue
1eissn
0277-3740issn
1536-4798journal_volume
16pub_type
杂志文章相关文献
CORNEA文献大全abstract::The records of 39 patients undergoing 40 consecutive penetrating keratoplasties were reviewed to identify donor factors that might correlate with the presence of an epithelial defect on the first postoperative day. Of the 40 transplanted corneas, 13 (32.5%) had no epithelial defect, 18 (45%) had some epithelial defect...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract:PURPOSE:To determine the effects of single radial or horizontal suture placement in 2-step clear corneal incision (CCI) wound apposition and permeability to particles of India ink. METHODS:Five fresh human globes were included. Two 25-gauge needles connected to a saline solution bag and to a digital manometer were ins...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31824d0d45
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:To report a solitary epibulbar neurofibroma in 2 elderly patients without systemic neurofibromatosis. METHODS:Case reports and literature review. RESULTS:A 67-year-old man presented with a 2-month history of left epibulbar mass. On slit-lamp examination, an 8- × 8-mm amelanotic, translucent, gelatinous, circu...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000370
更新日期:2015-04-01 00:00:00
abstract:PURPOSE:Study aimed to examine buttons removed from patients originally grafted for KC (group 1) for signs of recurrence at a cellular level and compare them with buttons removed from patients originally grafted for other conditions (group 2). The study further aimed to compare buttons from group 1 exhibiting high asti...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181967024
更新日期:2009-07-01 00:00:00
abstract:PURPOSE:To evaluate the prevalence of undiagnosed and asymptomatic human immunodeficiency virus (HIV) infection in patients with ocular surface squamous neoplasia (OSSN) in a referral hospital in Karnataka, South India. METHODS:A consecutive series of patients presenting with OSSN were evaluated in an academic center ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3182479aed
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:To report the case of a patient who initially presented with primary acquired melanosis (PAM) without atypia of the conjunctiva and later developed lentigo maligna of the eyelids and PAM with atypia of the conjunctiva. We illustrate the utility of combination topical therapy with adjunctive cryotherapy to treat...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000277
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:We aimed to investigate the possible association of proteoglycans with D-periodic collagen fibrils in the human cornea and sclera, using energy-filtering transmission electron microscopy (EF-TEM) and atomic force microscopy (AFM). METHODS:Human cornea and sclera were digested with keratanase to eliminate kerat...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200108000-00019
更新日期:2001-08-01 00:00:00
abstract:PURPOSE:The aim of this study was to estimate both the direct and indirect annual cost of managing dry eye disease (DED) in the United States from a societal and a payer's perspective. METHODS:A decision analytic model was developed to estimate the annual cost for managing a cohort of patients with dry eye with differ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181f7f363
更新日期:2011-04-01 00:00:00
abstract:PURPOSE:To describe a new technique for donor insertion in cases of Descemet-stripping automated endothelial keratoplasty (DSAEK). METHODS:This is a retrospective case series study of a novel method to introduce the donor tissue in DSAEK. This is a report of 16 cases that underwent the DSAEK procedure. The surgical te...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31816f62bd
更新日期:2008-08-01 00:00:00
abstract::Secondary corneal amyloidosis is a rare finding and only 17 cases have been reported in the literature. A case of unilateral secondary localized corneal amyloidosis is presented in a patient with bilateral interstitial keratitis and other stigmata of tertiary syphilis. ...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1990-04-01 00:00:00
abstract:PURPOSE:To investigate the regulation of matrix metalloproteinase (MMP)-3 and MMP-13 expression over time and in the presence of cyclosporine A (CsA) in primary cultured human pterygium fibroblasts. We also examined the effects of CsA on cultured human pterygium fibroblasts. METHODS:Primary cultured human pterygium fi...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000477
更新日期:2015-09-01 00:00:00
abstract:PURPOSE:To report a case of recurrent herpes simplex virus (HSV) epithelial keratitis after intravitreal triamcinolone acetonide injection for the treatment of diabetic macular edema. METHODS:Case report. RESULTS:We describe a case of a 59-year-old woman with a history of ocular HSV disease and severe proliferative d...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318041f0c0
更新日期:2007-06-01 00:00:00
abstract::Eight pseudomonal species were involved in 106 invasive infections of the eye; all were community acquired. Eighteen percent of the total and 9% of the Pseudomonas aeruginosa strains were gentamicin resistant, as defined using conventional criteria. All 10 cases of "resistant" pseudomonal (nine P. aeruginosa) keratiti...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1989-09-01 00:00:00
abstract::Penetrating keratoplasty (PKP) in conjunction with postoperative corticosteroids may reactivate latent herpes simplex virus type 1 (HSV-1) to cause persistent postoperative epithelial defects. The clinical diagnosis of HSV keratitis after penetrating keratoplasty is difficult because the postoperative appearance may b...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:PURPOSE:To evaluate changes in the anterior chamber of eyes that have undergone Descemet membrane endothelial keratoplasty (DMEK) and to identify factors that affect these changes. METHODS:This retrospective study included 25 pseudophakic eyes of 25 patients who underwent DMEK. We determined the preoperative and posto...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002535
更新日期:2020-09-29 00:00:00
abstract:PURPOSE:To present outcomes of combined pars plana vitrectomy, silicone oil (SO) injection, and permanent keratoprosthesis (Kpro) procedure in prephthisical eyes. METHODS:All 3 patients were monocular with chronic severe hypotony, aphakia, and total corneal opacity in their vital eye. Preoperative visual acuity ranged...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181e289a4
更新日期:2010-12-01 00:00:00
abstract:PURPOSE:Meta-analysis to compare pterygium surgery outcomes using limbal conjunctival autograft (LCAG) and other techniques. METHODS:A comprehensive literature search was conducted through June 2011 using PubMed, Embase, and the Cochrane Registry to identify all randomized control trials reported so far, comparing the...
journal_title:Cornea
pub_type: 杂志文章,meta分析
doi:10.1097/ICO.0b013e31823cbecb
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:To report the histopathologic findings in the host tissue of 2 human keratoconic corneas undergoing maximum-depth anterior lamellar keratoplasty (MDALK) using the manual dissection technique described by Melles. METHODS:Corneal buttons were examined from 2 patients with keratoconus who underwent MDALK using th...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000179930.97651.8f
更新日期:2006-09-01 00:00:00
abstract:PURPOSE:To assess donor rim culture results and outcomes of ocular infections in the Cornea Preservation Time Study (CPTS). METHODS:Donor corneal rim cultures were optional. Donor characteristics were assessed for association with positive cultures using the Fisher exact test and Poisson regression analyses. Incidence...
journal_title:Cornea
pub_type: 杂志文章,多中心研究
doi:10.1097/ICO.0000000000001654
更新日期:2018-09-01 00:00:00
abstract:PURPOSE:To report the use of excimer laser phototherapeutic keratectomy (PTK) in the treatment of corneal subepithelial nodular scarring in a child with Rothmund-Thomson syndrome (RTS), a form of ectodermal dysplasia. METHODS:A case report and review of the literature. RESULTS:Excimer laser PTK successfully treated t...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200001000-00022
更新日期:2000-01-01 00:00:00
abstract:PURPOSE:To describe the clinical and in vivo confocal microscopic findings of the cornea in 2 male siblings with Maroteaux-Lamy syndrome. METHODS:Two male siblings 27 and 22 years of age who had been diagnosed with Maroteaux-Lamy syndrome underwent ophthalmologic assessment. In vivo confocal microscopy of their cornea...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31802be383
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:The purpose of this research is 2-fold. First of all, the level of keratopathy development in patients with congenital aniridia is studied. In addition, a correlation between the effects of ocular surgery on the severity of keratopathy is made. METHODS:A thorough search for the total number of patients with an...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181d20493
更新日期:2010-10-01 00:00:00
abstract:PURPOSE:To examine the cornea of patients with Marfan syndrome in comparison with a control group by using the in vivo confocal microscope. METHODS:Twenty-four eyes of 12 patients with Marfan syndrome had their corneas examined using the in vivo confocal microscope Heidelberg Retina Tomograph (HRT) II/Rostock Cornea M...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31806c7729
更新日期:2007-08-01 00:00:00
abstract:PURPOSE:To describe a case of antiepiligrin cicatricial pemphigoid with unusual ocular manifestations and its remission after surgical removal of gastric carcinoma. METHODS:We describe a 61-year-old Japanese man with antiepiligrin cicatricial pemphigoid. RESULTS:He presented with conjunctival injection and discharge ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200007000-00033
更新日期:2000-07-01 00:00:00
abstract:PURPOSE:To identify and develop an efficient technique to separate the lenticule edge in small incision lenticule extraction (SMILE). METHODS:Four hundred eyes of 400 consecutive patients with myopia assigned to receive SMILE were included in the study. Eyes with poor-quality laser treatment were excluded, and the sec...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001691
更新日期:2018-10-01 00:00:00
abstract:PURPOSE:To measure subbasal nerve density and orientation in normal human corneas across a broad age range. METHODS:Sixty-five normal corneas of 65 subjects were examined by using tandem scanning confocal microscopy. Ages of subjects ranged from 15 to 79 years (mean 46 +/- 19 years), with 5 subjects from each hemideca...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000154387.51355.39
更新日期:2005-08-01 00:00:00
abstract::To compare the efficacy of ciprofloxacin hydrochloride ointment with that of ciprofloxacin drops for treatment of experimental Pseudomonas keratitis, rabbit eyes were infected by intrastromal injection of 10(3) colony-forming units (CFU) log-phase P. aeruginosa. Infected and uninfected eyes were treated with either 0....
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199303000-00008
更新日期:1993-03-01 00:00:00
abstract::In order to evaluate the effect of a commonly used sodium hyaluronate preparation (Healon, Pharmacia AB, Uppsala, Sweden) on the incidence of endothelial rejection, endothelial cell loss, intraocular pressure, and corneal thickness after penetrating keratoplasty, we conducted a randomized clinical trial. Patients were...
journal_title:Cornea
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1990-10-01 00:00:00
abstract:PURPOSE:In humans, loss-of-function mutations in the gene encoding Chordin-like 1 (CHRDL1) cause X-linked megalocornea (MGC1), characterized by bilateral corneal enlargement, decreased corneal thickness, and increased anterior chamber depth (ACD). We sought to determine whether Chrdl1 knockout (KO) mice would recapitul...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002371
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of superficial keratectomy and conjunctival advancement hood flap (SKCAHF) for the treatment of bullous keratopathy in canine patients. METHODS:Nine dogs (12 eyes) diagnosed with progressive corneal edema underwent superficial keratectomy followed by placement of conjunctival advanceme...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000966
更新日期:2016-10-01 00:00:00