Abstract:
PURPOSE:The purpose of this research is 2-fold. First of all, the level of keratopathy development in patients with congenital aniridia is studied. In addition, a correlation between the effects of ocular surgery on the severity of keratopathy is made. METHODS:A thorough search for the total number of patients with aniridia in Sweden and Norway was performed. One hundred eighty-one patients were identified and 124 (69%) of these were examined. Three artificial eyes, 16 eyes with corneal transplants, and 1 eye with a corneal limbal allograft were excluded from the study. All participating patients underwent clinical ophthalmologic examinations, including photographs, and their medical history was recorded. A slit lamp was used to examine the presence of keratopathy. RESULTS:Visible keratopathy was found in 80% of the eyes. Keratopathy that caused impaired visual acuity was found in 26% of the eyes. The study displayed a significant correlation between the level of keratopathy and the patient's age. A significant correlation between the level of keratopathy and intraocular surgery exists. This is irrespective of the patient's age. The study also found that irrespective of the patient's age, a significant correlation between the level of keratopathy and impaired corneal sensitivity exists. CONCLUSIONS:This research identified the presence of visible keratopathy in 80% of eyes. In addition, 26% of eyes had a keratopathy level that caused visual disturbances. The study showed that the prevalence and severity of keratopathy increased with the patient's age. Further conclusions are that intraocular surgery increases the severity of keratopathy and that the severity of keratopathy is correlated to reduced corneal sensitivity. Finally, extreme care should be taken when selecting patients for intraocular surgery because this procedure can trigger the development of keratopathy.
journal_name
Corneajournal_title
Corneaauthors
Edén U,Riise R,Tornqvist Kdoi
10.1097/ICO.0b013e3181d20493subject
Has Abstractpub_date
2010-10-01 00:00:00pages
1096-102issue
10eissn
0277-3740issn
1536-4798journal_volume
29pub_type
杂志文章相关文献
CORNEA文献大全abstract:PURPOSE:To determine the effects of single radial or horizontal suture placement in 2-step clear corneal incision (CCI) wound apposition and permeability to particles of India ink. METHODS:Five fresh human globes were included. Two 25-gauge needles connected to a saline solution bag and to a digital manometer were ins...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31824d0d45
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:Pterygium excision with conjunctival limbal autograft (CLAG) has been used successfully for prevention of pterygium recurrence. However, long-term follow-up data in the literature are lacking regarding CLAG. METHODS:Retrospective chart review and standard statistical analysis were performed. The records of 289...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000597
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:To evaluate visual, refractive, and corneal topography outcomes in eyes with keratoconus that have undergone exchange/adjustment surgery with a new intrastromal corneal ring segment (ICRS) combination after unsuccessful visual and/or refractive outcomes after primary ICRS surgery. METHODS:A retrospective nonra...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001449
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:To report on surgical reduction of oculodermal melanosis in 6 patients presenting with severe episcleral pigmentation. METHODS:After informed consent was obtained, surgical reduction of ocular pigmentation with ocular dermal melanosis was performed on 3 children, 2 girls and 1 boy male, who were cosmetically h...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000151546.00489.c9
更新日期:2005-05-01 00:00:00
abstract:PURPOSE:Comparison of corneal pachymetry assessment with ultrasound and Orbscan II using acoustic factor and subtraction methods. METHODS:Ultrasound and Orbscan pachymetry for all patients with LASIK performed between July 2002 and May 2003 were retrospectively analyzed. Comparison between the 2 preoperative measureme...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000240089.26467.dc
更新日期:2006-12-01 00:00:00
abstract:PURPOSE:The purpose of this study was to report the first case of fungal keratitis resulting from Thielavia sp. METHODS:We conducted a retrospective chart review. RESULTS:A 10-year old girl presented 2 weeks after ocular plant injury with pain and corneal stromal infiltration with central ulceration and ill-defined m...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31819717f4
更新日期:2009-10-01 00:00:00
abstract:PURPOSE:To investigate the in vivo, corneal, biomechanical changes after corneal collagen cross-linking (CXL) using the Ocular Response Analyzer (ORA) in patients with keratoconus and post-laser in situ keratomileusis (LASIK) ectasia. METHODS:Single-center, prospective, randomized, controlled, clinical trial. After CX...
journal_title:Cornea
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/ICO.0b013e31821eea66
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:To compare the corneal and aqueous penetration and pharmacokinetics of gatifloxacin 0.3% and moxifloxacin 0.5% ophthalmic solutions and their effect on corneal reepithelialization after penetrating keratoplasty. METHODS:In this randomized, open-label, parallel-controlled study, corneal and aqueous penetration ...
journal_title:Cornea
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/ICO.0b013e3181608561
更新日期:2008-04-01 00:00:00
abstract::The action of hydrogen peroxide on soluble proteins of the rat cornea has been evaluated. Two major corneal proteins are found to be oxidized by 10 mM hydrogen peroxide. Protein sequence and antibody recognition has shown one of the proteins to be albumin. Treatment of pure rat or human albumin with hydrogen peroxide ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199211000-00014
更新日期:1992-11-01 00:00:00
abstract:PURPOSE:To evaluate the therapeutic effect of corneal cross-linking (CXL) in 2 cases of bullous keratopathy combined with corneal ulcer. METHODS:Two patients (2 eyes) were recruited for the sake of the study. Both suffered from bullous keratopathy and presented a gradually deteriorating, vision-threatening, central co...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181a81802
更新日期:2010-02-01 00:00:00
abstract:PURPOSE:To review ocular injuries secondary to airbag deployment that were seen in our institution and were reported in the literature. METHODS:Patients examined at our institution between 1997 and 2000 were evaluated for ocular injuries caused by airbags. A review of the medical literature using Medline was performed...
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/00003226-200103000-00009
更新日期:2001-03-01 00:00:00
abstract::Corneal neovascularization complicates many anterior segment diseases. Corneal laser photocoagulation using yellow light (577 nm) has been shown to reduce corneal neovascularization. No histopathologic studies of the effects of this treatment on the eye have been reported, however. Target (cornea) and nontarget (iris,...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199305000-00001
更新日期:1993-05-01 00:00:00
abstract:PURPOSE:To confirm the ocular tropism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by evaluating the expression of viral entry factors in human ocular tissues using immunohistochemistry. METHODS:Fresh donor corneas and primary explant cultures of corneal, limbal, and conjunctival epithelial cells we...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002509
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:To examine the effect of successful repositioning/rebubbling of the graft on endothelial cell counts (ECCs) in eyes after Descemet stripping automated endothelial keratoplasty. METHODS:This retrospective study reviewed the outcomes of 58 eyes that underwent Descemet stripping automated endothelial keratoplasty...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181cb40f6
更新日期:2010-08-01 00:00:00
abstract:PURPOSE:To find the level of dissection in keratoconic corneas undergoing deep anterior lamellar keratoplasty (DALK) using the big-bubble technique. METHODS:In 3 keratoconic eyes that underwent DALK, the operation was converted into penetrating keratoplasty after complete big-bubble formation because of extensive tear...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181ba7016
更新日期:2010-04-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the outcome of penetrating keratoplasties, at the University Eye Hospital, Ludwig-Maximilians-University, Munich, Germany, using organ-cultured donor corneas and to identify preoperative risk factors, which may influence the event of graft failure. METHODS:In this study, 3...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000225
更新日期:2014-11-01 00:00:00
abstract:PURPOSE:To describe the management of three cases of corneal perforation associated with silicone oil in the anterior chamber. METHODS:Review of 3 case records. RESULTS:Three cases of perforation associated with silicone oil in the anterior chamber are reviewed. One patient required gluing and a bandage contact lens,...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31807a28f0
更新日期:2007-10-01 00:00:00
abstract:PURPOSE:To report the histologic findings in three explanted osteo-odontokeratoprosthesis (OOKP) laminae. METHODS:The osteodental lamina of patient 1 with linear IgA bullous dermatosis had to be explanted 15 months after OOKP surgery because of permanent leakage after the resorption of the inferior half of the bone/de...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200205000-00013
更新日期:2002-05-01 00:00:00
abstract:PURPOSE:To report the association between colonization of contact lenses with Streptococcus pneumoniae and the observation of corneal infiltrative events in a group of patients wearing disposable hydrogel lenses on an extended-wear schedule. METHODS:In a prospective clinical trial, 330 patients wore disposable hydroge...
journal_title:Cornea
pub_type: 临床试验,杂志文章
doi:10.1097/00003226-199905000-00008
更新日期:1999-05-01 00:00:00
abstract:PURPOSE:To report a case of infectious crystalline keratopathy caused by Gemella haemolysans. METHODS:Observational case report. A 65-year-old woman underwent penetrating keratoplasty for contact lens-related Acanthamoeba keratitis and developed a nonhealing epithelial defect. Despite continued prophylaxis with topica...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000240090.44195.a3
更新日期:2006-12-01 00:00:00
abstract:PURPOSE:To evaluate the effect of mitomycin C (MMC) on the exacerbation of corneal opacity that occurs in patients with granular corneal dystrophy type II (GCD II) after refractive corneal surface ablation. METHODS:Ten eyes of patients with GCD II who underwent refractive corneal surface ablation with MMC were compare...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181c3258a
更新日期:2010-05-01 00:00:00
abstract::Here we report a new method for image analysis of the corneal stroma. To obtain the biometric characteristics of a given area, we perform three different treatments of the same image. These automated predictions closely match each parameter (length, surface area, etc.), as measured manually by a "blind investigator." ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199107000-00009
更新日期:1991-07-01 00:00:00
abstract:PURPOSE:To investigate the efficacy and safety of subconjunctival bevacizumab injection for the treatment of impending recurrent pterygium. METHODS:A prospective, randomized, single-masked, controlled trial was conducted in 80 patients with impending recurrent pterygium. Patients were randomized into 4 groups using ra...
journal_title:Cornea
pub_type: 杂志文章,随机对照试验
doi:10.1097/ICO.0b013e3182151e0e
更新日期:2012-02-01 00:00:00
abstract:PURPOSE:We sought to illustrate the difficulty in managing uncommon, pigmented mold-related corneal ulceration and to highlight the role of itraconazole in treating these patients. METHOD:We describe the management and clinical course of a patient with a recurring corneal infection caused by Fonsecaea pedrosoi and dis...
journal_title:Cornea
pub_type: 杂志文章,评审
doi:
更新日期:1997-03-01 00:00:00
abstract:PURPOSE:Decorin is a small chondroitin sulfate proteoglycan that inhibits vascular endothelial cell migration and tube formation. Membrane type 1-matrix metalloproteinase (MT1-MMP) has been shown to be an important angiogenic enzyme in the cornea. We evaluated the specific role of MT1-MMP in decorin cleavage in the cor...
journal_title:Cornea
pub_type: 杂志文章,收录出版
doi:10.1097/ICO.0b013e31822816e0
更新日期:2011-10-01 00:00:00
abstract:PURPOSE:To investigate the severity of keratoconus in terms of corneal elevation differences with 2 different reference surfaces using topographic analysis. METHODS:Eighty-six eyes of 50 patients with keratoconus of various clinical stages (61 male and 25 female eyes) with mean age of 37.3 ± 11.6 years were evaluated....
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0B013E31823D1EE0
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To compare the effects of levobunolol hydrochloride and timolol maleate on tear volume, precorneal tear film stability, and corneal epithelial barrier function in normal human eyes. SUBJECTS AND METHODS:The study population consisted of 14 healthy volunteers. To obtain pretreatment baseline values, we determin...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200311000-00001
更新日期:2003-11-01 00:00:00
abstract:PURPOSE:To describe the clinical characteristics, diagnosis, treatment, and visual outcome of 61 cases of Fusarium keratitis in Mexico. METHODS:Retrospective, comparative study of 61 patients with clinically and culture-confirmed Fusarium keratitis, who were attended at an eye hospital in Mexico City from 1981 to 2001...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31819bc2ea
更新日期:2009-07-01 00:00:00
abstract::Infectious keratitis after penetrating keratoplasty can be devastating to the survival of the graft and its visual outcome. From November 1989 to October 1994, we treated 41 episodes of late microbial keratitis among 354 consecutive penetrating keratoplasty patients and reviewed their medical records retrospectively. ...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract:PURPOSE:To report a case of ocular manifestations after a primary varicella infection. METHODS:Review of the literature and a case report of a 10-year-old male patient with history of blurry vision and an enlarged pupil 2 months after a varicella infection. Examination revealed uveitis, interstitial keratitis, and int...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000224651.19837.6c
更新日期:2006-08-01 00:00:00