Topical interferon alpha-2a treatment of herpes simplex keratitis resistant to multiple antiviral medications in an immunosuppressed patient.

abstract：PURPOSE:To describe the varied presentations of posterior keratoconus. METHODS:This is a 3-year institute-based retrospective study report from June 2015 to June 2018 that describes 13 eyes of 12 patients with varied presentations of posterior keratoconus, evaluating tomographic changes using Scheimpflug corneal tomog...

journal_title：Cornea

authors： Ganesan N,Narayana S,Kasturi N,Kaliaperumal S,Srinivasan R,Vallinayagam M

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:To compare dry eye disease parameters between small incision lenticule extraction (SMILE) and laser subepithelial keratomileusis (LASEK). METHODS:This prospective, nonrandomized study included 39 eyes of 39 patients who underwent SMILE (n = 19) and LASEK (n = 20). Dry eye disease parameters included Ocular Sur...

journal_title：Cornea

authors： Chung B,Choi M,Lee KY,Kim EK,Seo KY,Jun I,Kim KY,Kim TI

更新日期：2020-04-01 00:00:00

abstract：:Severe microbial keratitis developed in a 74-year-old women receiving long-term corticosteroids. Corneal smears revealed slender, fusiform gram-negative bacilli, but the lesion continued to worsen despite intensive antibiotic treatment. After several days, Capnocytophaga sputigena was identified on culture. Specific a...

journal_title：Cornea

authors： Ormerod LD,Foster CS,Paton BG,Haaf J,Baker AS

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:In humans, loss-of-function mutations in the gene encoding Chordin-like 1 (CHRDL1) cause X-linked megalocornea (MGC1), characterized by bilateral corneal enlargement, decreased corneal thickness, and increased anterior chamber depth (ACD). We sought to determine whether Chrdl1 knockout (KO) mice would recapitul...

journal_title：Cornea

authors： Chen D,Liu Y,Shu G,Chen C,Sullivan DA,Kam WR,Hann S,Fowler M,Warman ML

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:To determine if concurrent use of 5% natamycin and 2% econazole offers greater benefits than monotherapy with 5% natamycin for the management of fungal keratitis. METHODS:Subjects presenting to the cornea service were treated with 5% natamycin and 2% econazole used concurrently. We compared the results with a ...

journal_title：Cornea

authors： Prajna NV,Nirmalan PK,Mahalakshmi R,Lalitha P,Srinivasan M

更新日期：2004-11-01 00:00:00

abstract：:During wound healing, corneal tissue has to restore its transparency for proper vision. Various cytokines and growth factors are believed to orchestrate cellular behavior in a healing cornea. This review summarizes the roles of 1 such factor, the proinflammatory cytokine tumor necrosis factor (TNF)-alpha, in the proce...

journal_title：Cornea

authors： Saika S

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:To evaluate the therapeutic effect of corneal cross-linking (CXL) in 2 cases of bullous keratopathy combined with corneal ulcer. METHODS:Two patients (2 eyes) were recruited for the sake of the study. Both suffered from bullous keratopathy and presented a gradually deteriorating, vision-threatening, central co...

journal_title：Cornea

authors： Kozobolis V,Labiris G,Gkika M,Sideroudi H,Kaloghianni E,Papadopoulou D,Toufexis G

更新日期：2010-02-01 00:00:00

abstract：:Regulatory T cells (Tregs) are essential for the maintenance of immune homeostasis. Studies of Treg are not only necessary for understanding the mechanism of immune homeostasis but also extremely useful for the development of treatments of various immune diseases. Forkhead box P3 (Foxp3) was identified as the master g...

journal_title：Cornea

authors： Ito M,Iizuka-Koga M,Ando M,Yoshimura A

更新日期：2018-11-01 00:00:00

abstract：:Meibomian glands secrete the oily layer of the tear film, which prevents excessive evaporation of tear fluid. Dysfunction of meibomian glands is not only one of the causes of evaporative dry eye but also one of the main causes of entire dry eye. To understand the pathophysiology of meibomian gland dysfunction, it is i...

journal_title：Cornea

authors： Arita R,Fukuoka S,Morishige N

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:To determine the stability of the laser in situ keratomileusis (LASIK) flap in a rabbit model when subjected to vertical acceleration at nine times the force of gravity (+9 Gz) in an aircraft cockpit ejection simulator. METHODS:Thirty-six eyes from 25 New Zealand white rabbits underwent LASIK flap creation wit...

journal_title：Cornea

authors： Goodman RL,Johnson DA,Dillon H,Edelhauser HF,Waller SG

更新日期：2003-03-01 00:00:00

abstract：PURPOSE:To report that spontaneous postkeratoplasty wound dehiscence or gaps caused by suture removal may occur years after penetrating and deep lamellar keratoplasty. METHODS:We retrospectively reviewed the medical records of 667 keratoplasty patients (890 eyes). This study included 8 eyes of 8 patients (3 men and 5 ...

journal_title：Cornea

authors： Fujii S,Matsumoto Y,Fukui M,Fujitake J,Kawakita T,Shimmura S,Tsubota K

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:We analyzed laboratory results from corneal ulcers seen from 1976 to 1999 at the Francis I. Proctor Foundation, a referral center in San Francisco, to determine the relative frequencies of pathogens and to analyze for trends in frequencies of the most common pathogens. The results were compared with a previou...

journal_title：Cornea

authors： Varaprasathan G,Miller K,Lietman T,Whitcher JP,Cevallos V,Okumoto M,Margolis TP,Yinghui M,Cunningham ET Jr

更新日期：2004-05-01 00:00:00

abstract：PURPOSE:We report 2 cases in which cataract extraction with a foldable acrylic toric intraocular lens (IOL) implantation was used to correct (irregular) corneal astigmatism in patients with keratoconus and cataract. METHODS:Case 1 was a 78-year-old man with cataract and keratoconus in the left eye. He underwent phacoe...

journal_title：Cornea

authors： Visser N,Gast ST,Bauer NJ,Nuijts RM

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:The aim of this study was to introduce a newly developed graft inserter for Descemet stripping automated endothelial keratoplasty, which can be readily used with 1 hand, and to examine endothelial cell loss (ECL) after graft insertion using this new inserter in an ex vivo rabbit model. METHODS:Rabbit corneal g...

journal_title：Cornea

authors： Toyama T,Honda N,Usui T,Amano S

更新日期：2014-04-01 00:00:00

abstract：:Twelve FITC-conjugated lectins were used to establish a reaction pattern with cellular and noncellular components in fresh-frozen and formalin-fixed paraffin sections of 11 normal human corneas. In frozen sections the epithelium demonstrated the most active lectin staining; keratocytes and endothelium stained to a les...

journal_title：Cornea

authors： Brandon DM,Nayak SK,Binder PS

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:One of the most disturbing trends in recent years is the growth of resistant strains of bacteria with the simultaneous dearth of new antimicrobial agents. Thus, new antimicrobial agents for the use on the ocular surface are needed. METHODS:We synthesized a variety of ionic liquid compounds, which possess 2 pos...

journal_title：Cornea

authors： O'Toole GA,Wathier M,Zegans ME,Shanks RM,Kowalski R,Grinstaff MW

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:To evaluate the feasibility and cut quality of corneal trephination in human donor corneal tissue with the femtosecond laser. METHODS:Twelve human corneoscleral discs were inserted in an artificial anterior chamber. After corneal thickness measurement and tonometry, the cornea was mounted on a femtosecond lase...

journal_title：Cornea

authors： Meltendorf C,Schroeter J,Bug R,Kohnen T,Deller T

更新日期：2006-10-01 00:00:00

abstract：PURPOSE:To report a case of traumatic flap partial dislocation and subsequent diffuse lamellar inflammation 14 months after laser in situ keratomileusis (LASIK) retreatment. METHODS:Case report of a late flap dislocation that occurred during routine recreational activity (struck with a finger in the right eye while pl...

journal_title：Cornea

authors： Aldave AJ,Hollander DA,Abbott RL

更新日期：2002-08-01 00:00:00

abstract：PURPOSE:To report the histopathologic findings in the host tissue of 2 human keratoconic corneas undergoing maximum-depth anterior lamellar keratoplasty (MDALK) using the manual dissection technique described by Melles. METHODS:Corneal buttons were examined from 2 patients with keratoconus who underwent MDALK using th...

journal_title：Cornea

authors： Saw VP,Ng T,Crouch R,Maloof AJ

更新日期：2006-09-01 00:00:00

abstract：PURPOSE:To report keratouveitis arising from corneal penetration by a bristle worm seta (bristle). METHODS:We report on a 64-year-old woman presenting with uniocular pain, redness, reduced vision, discharge, and pustular rash of the hands after cleaning out her marine aquarium containing bristle worms and rubbing her ...

journal_title：Cornea

authors： Kirk J,Gunn D,Wong N,Minchin E,Darcy K

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:This study was designed to report a case of biopsy-proven mucous membrane pemphigoid with severe bronchial involvement in a young woman. METHODS:Case report of a 17-year-old girl who presented with worsening dyspnea, skin rash, and bilateral ocular injection, symblepharon, and fornix foreshortening. Conjunctiv...

journal_title：Cornea

authors： Gamm DM,Harris A,Mehran RJ,Wood M,Foster CS,Mootha VV

更新日期：2006-05-01 00:00:00

abstract：PURPOSE:To describe the clinical signs of Descemet membrane (DM) detachment due to forceps-related birth injury and its subsequent management using optical coherence tomography. METHODS:Case report. RESULTS:A 3-day-old term infant presented with left eye corneal clouding and a definitive history of traumatic forceps-...

journal_title：Cornea

authors： Kancherla S,Shue A,Pathan MF,Sylvester CL,Nischal KK

更新日期：2017-03-01 00:00:00

abstract：PURPOSE:Videokeratoscopes provide a wealth of information about the topography of the ocular surface. Although there have been numerous studies of the accuracy and precision of videokeratoscopes with inanimate test objects, little information exists on their precision (repeatability) for real eyes. METHODS:To investig...

journal_title：Cornea

authors： Buehren T,Collins MJ,Iskander DR,Davis B,Lingelbach B

更新日期：2001-11-01 00:00:00

abstract：PURPOSE:To test the hypothesis that patients with keratoconus and pellucid who have glaucoma or are glaucoma suspects have lower corneal hysteresis (CH) and/or corneal resistance factor (CRF) measurements compared with controls. METHODS:A prospective study at a tertiary eye center of patients with keratoconus and pell...

journal_title：Cornea

authors： Cohen EJ,Myers JS

更新日期：2010-09-01 00:00:00

abstract：:Epithelialization of uveal structures is frequently difficult to diagnose clinically and may require scanning and/or transmission electron microscopy to detect histologically. Since the scanning and transmission electron microscopic findings of progressive iris epithelialization have not previously been described, we ...

journal_title：Cornea

authors： Burris TE,Nordquist RE,Rowsey JJ

更新日期：1985-01-01 00:00:00

abstract：:Effective chemotherapy for Acanthamoeba keratitis has been hampered because of the marked resistance of the parasites to a variety of antimicrobial agents. In view of the fact that topical Brolene (propamidine isethionate) and neosporin are currently considered to be the medical treatment of choice in Europe, we sough...

journal_title：Cornea

authors： Alizadeh H,Silvany RE,Meyer DR,Dougherty JM,McCulley JP

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:To evaluate and compare the in vitro antimicrobial activity of levofloxacin versus ciprofloxacin and ofloxacin against ocular isolates from patients with bacterial conjunctivitis. METHODS:The in vitro antimicrobial susceptibilities of ocular isolates to levofloxacin, ofloxacin, and ciprofloxacin were determine...

journal_title：Cornea

authors： Graves A,Henry M,O'Brien TP,Hwang DG,Van Buskirk A,Trousdale MD

更新日期：2001-04-01 00:00:00

abstract：PURPOSE:To present long-term clinical and visual outcomes of patients with Peters anomaly. METHODS:The charts of all patients diagnosed with Peters anomaly from January 2000 to December 2012 were reviewed retrospectively. Peters anomaly was classified as type I (with no lens involvement) or type II (presence of kerato...

journal_title：Cornea

authors： Elbaz U,Strungaru H,Mireskandari K,Stephens D,Ali A

更新日期：2020-11-04 00:00:00

abstract：PURPOSE:To investigate the feasibility of corneal reconstruction utilizing cultured human corneal endothelial cells (HCECs). METHODS:We cultivated HCECs using culture dishes pre-coated with bovine corneal endothelial extracellular matrix. The effect of donor age on HCECs was investigated. We reconstructed corneas usin...

journal_title：Cornea

authors： Amano S

更新日期：2003-10-01 00:00:00

abstract：PURPOSE:To evaluate the effect of mitomycin C (MMC) on the exacerbation of corneal opacity that occurs in patients with granular corneal dystrophy type II (GCD II) after refractive corneal surface ablation. METHODS:Ten eyes of patients with GCD II who underwent refractive corneal surface ablation with MMC were compare...

journal_title：Cornea

authors： Ha BJ,Kim TI,Choi SI,Stulting RD,Lee DH,Cho HS,Kim EK

更新日期：2010-05-01 00:00:00