Mitomycin C does not inhibit exacerbation of granular corneal dystrophy type II induced by refractive surface ablation.

Abstract:

PURPOSE:To evaluate the effect of mitomycin C (MMC) on the exacerbation of corneal opacity that occurs in patients with granular corneal dystrophy type II (GCD II) after refractive corneal surface ablation. METHODS:Ten eyes of patients with GCD II who underwent refractive corneal surface ablation with MMC were compared with 10 eyes that were not treated with MMC. Best spectacle-corrected visual acuity, the degree of corneal opacity, and contrast sensitivity were evaluated at least 3 years after surgery. Corneal opacities were quantified using Pentacam densitometry maps. RESULTS:No measured between-group value showed a statistically significant difference. CONCLUSION:Simultaneous application of MMC does not prevent exacerbation of GCD II after refractive corneal surface ablation.

journal_name

Cornea

journal_title

Cornea

authors

Ha BJ,Kim TI,Choi SI,Stulting RD,Lee DH,Cho HS,Kim EK

doi

10.1097/ICO.0b013e3181c3258a

subject

Has Abstract

pub_date

2010-05-01 00:00:00

pages

490-6

issue

5

eissn

0277-3740

issn

1536-4798

journal_volume

29

pub_type

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