Model of epithelial downgrowth: III. Scanning and transmission electron microscopy of iris epithelialization.

Abstract:

:Epithelialization of uveal structures is frequently difficult to diagnose clinically and may require scanning and/or transmission electron microscopy to detect histologically. Since the scanning and transmission electron microscopic findings of progressive iris epithelialization have not previously been described, we examined a cat model of epithelial downgrowth for iris findings from 23 days through 4 months post-implantations of epithelium. Features associated with iris epithelialization included direct contact of iris with implanted epithelium, allowing initially rapid epithelialization of anterior iris structures, and slower epithelialization of posterior iris pigmented epithelium. The morphology of the migrating epithelium progressed from spindle shaped cells with small numbers of pseudopodia and microvillae to confluence of up to five layers of stratified epithelium with numerous surface microvilli. Anterior iris epithelial morphology consisted of cuboidal shaped cells with "looser" cell junctional interdigitations, versus a more squamous appearance of posterior iris epithelialization. A monolayer of lead cells or thin sheets of epithelium may be present well before a clinically apparent multicellular sheet of epithelium is seen.

journal_name

Cornea

journal_title

Cornea

authors

Burris TE,Nordquist RE,Rowsey JJ

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

249-55

issue

4

eissn

0277-3740

issn

1536-4798

journal_volume

4

pub_type

杂志文章

相关文献

CORNEA文献大全
  • Bilateral iridocorneal endothelial syndrome: case report and review of the literature.

    abstract::We present the case of a 47-year-old woman with bilateral iridocorneal endothelial syndrome. The iridocorneal endothelial syndrome has heretofore been considered a unilateral disorder. However, a review of the literature and examination of the patient presented in this report indicate that bilateral occurrence of the ...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/00003226-199407000-00015

    authors: Hemady RK,Patel A,Blum S,Nirankari VS

    更新日期:1994-07-01 00:00:00

  • The New Zealand National Eye Bank: survival and visual outcome 1 year after penetrating keratoplasty.

    abstract:PURPOSE:To identify potential donor, recipient, surgical, and postoperative factors that may influence survival and visual outcome of penetrating keratoplasty (PKP). METHODS:As part of a prospective longitudinal study, the electronic records of the New Zealand National Eye Bank were analyzed for the 10-year period fro...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3182014668

    authors: Patel HY,Ormonde S,Brookes NH,Moffatt SL,Sherwin T,Pendergrast DG,McGhee CN

    更新日期:2011-07-01 00:00:00

  • Microsporidial stromal keratitis masquerading as acute graft rejection.

    abstract:PURPOSE:To describe the clinical features, disease course, management, and visual outcome of stromal microsporidial keratitis involving the corneal graft in an immunocompetent patient. METHODS:Case report. RESULTS:We report the case of a 21-year-old immunocompetent woman, who underwent penetrating keratoplasty for ad...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000337

    authors: Pradhan S,Mascarenhas J,Srinivasan M

    更新日期:2015-03-01 00:00:00

  • Antimicrobial effect of ciprofloxacin, povidone-iodine, and gentamicin in the decontamination of human donor globes.

    abstract:PURPOSE:Clinical research addressing the issue of donor globe decontamination is yet to establish convincing data for the optimal choice of an antimicrobial agent. METHODS:In a donor-globe decontamination study, the antimicrobial effectiveness of a fluoroquinolone antibiotic (ciprofloxacin, 0.3%) was evaluated for the...

    journal_title:Cornea

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00003226-199801000-00008

    authors: Gopinathan U,Reddy MK,Nadkarni MS,Dasari S,Rao GN

    更新日期:1998-01-01 00:00:00

  • Endophthalmitis in Advanced Microbial Keratitis: Risk Factors and Examination Findings.

    abstract:PURPOSE:To evaluate clinical and ultrasonographic findings associated with advanced microbial keratitis with concurrent endophthalmitis. METHODS:We performed a retrospective analytical study of patients with severe microbial keratitis who underwent ocular ultrasonography for possible endophthalmitis at our institution...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002349

    authors: Christopher KL,Hood CT,Mian SI,Ayres B

    更新日期:2020-09-01 00:00:00

  • Terrien marginal degeneration presenting with spontaneous corneal perforation.

    abstract:PURPOSE:To report spontaneous corneal perforation as a presenting sign of unilateral Terrien marginal degeneration in a young adult. METHODS:A 19-year-old woman presented with sudden loss of vision in her left eye of 1-day duration. Examination revealed superior corneal thinning with superficial vascularization and se...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000226367.41925.ab

    authors: Srinivasan S,Murphy CC,Fisher AC,Freeman LB,Kaye SB

    更新日期:2006-09-01 00:00:00

  • Very low risk of light-induced retinal damage during Boston keratoprosthesis surgery: a rabbit study.

    abstract:PURPOSE:The aim of this study was to assess the possibility of light damage to the retina by a surgical microscope during implantation of a Boston Keratoprosthesis (B-KPro) in rabbits. METHODS:The retinal irradiance from a Zeiss OPMI Lumera S7 operating microscope was measured at the working distance (16.5 cm). Light ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000029

    authors: Salvador-Culla B,Behlau I,Sayegh RR,Stacy RC,Dohlman CH,Delori F

    更新日期:2014-02-01 00:00:00

  • Incidence and clinical characteristics of enterococcus keratitis.

    abstract:PURPOSE:To study the incidence, clinically relevant factors, and antibiotic sensitivity profile of cases of enterococcal keratitis presenting at the New York Eye and Ear Infirmary between January 1, 1996, and December 31, 2005. METHODS:The records of all corneal cultures submitted to the Microbiology Laboratory of the...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31816f633b

    authors: Rau G,Seedor JA,Shah MK,Ritterband DC,Koplin RS

    更新日期:2008-09-01 00:00:00

  • Measures for preventing recurrence after pterygium surgery.

    abstract:PURPOSE:To introduce an improved technique of pterygium surgery and to compare postoperative results between this technique and previous techniques. METHODS:In a retrospective survey, the records of 216 consecutive eyes with primary pterygium that underwent surgery by three different techniques were reviewed. The new ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200110000-00006

    authors: Akura J,Kaneda S,Matsuura K,Setogawa A,Takeda K,Honda S

    更新日期:2001-10-01 00:00:00

  • Case Report: Suspected Donor Transmission of Acanthamoeba Keratitis After Deep Anterior Lamellar Keratoplasty.

    abstract:PURPOSE:In our report, we present a suspected case of donor-derived Acanthamoeba keratitis after deep anterior lamellar keratoplasty. To the authors' knowledge, there have been no confirmed cases of Acanthamoeba keratitis transmission through corneal transplantation. METHODS:Deep anterior lamellar keratoplasty was per...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002517

    authors: Ward MS,Bontu S,Martheswaran T,Mamalis N,Moshirfar M

    更新日期:2020-09-16 00:00:00

  • In vitro amoebicidal activity of propamidine and pentamidine isethionate against Acanthamoeba species and toxicity to corneal tissues.

    abstract::Effective chemotherapy for Acanthamoeba keratitis has been hampered because of the marked resistance of the parasites to a variety of antimicrobial agents. In view of the fact that topical Brolene (propamidine isethionate) and neosporin are currently considered to be the medical treatment of choice in Europe, we sough...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Alizadeh H,Silvany RE,Meyer DR,Dougherty JM,McCulley JP

    更新日期:1997-01-01 00:00:00

  • Anterior-Segment Optical Coherence Tomography and Scanning Electron Microscopy to Evaluate Corneal Epithelial Changes in Patients Undergoing Glaucoma Therapy.

    abstract:PURPOSE:To measure corneal epithelial thickness (CET) in patients with glaucoma using anterior-segment optical coherence tomography and to evaluate CET changes in relation to corneal epithelial microvilli analyzed by scanning electron microscopy (SEM). METHODS:Twenty-two eyes (16 patients) being treated with preservat...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001752

    authors: Cennamo G,Montorio D,Del Prete S,Del Prete A,Cennamo G

    更新日期:2018-12-01 00:00:00

  • Absorption of topical moxifloxacin ophthalmic solution into human aqueous humor.

    abstract:PURPOSE:To investigate the absorption of moxifloxacin into human aqueous humor after administration of moxifloxacin hydrochloride ophthalmic solution, 0.5% as base. METHODS:Cataract patients were randomly allocated to receive 1 drop every 15 minutes for 4 doses before surgery (group 1) or 1 drop 4 times per day on the...

    journal_title:Cornea

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/01.ico.0000157423.78275.a2

    authors: Katz HR,Masket S,Lane SS,Sall K,Orr SC,Faulkner RD,McCue BA,Dahlin DC

    更新日期:2005-11-01 00:00:00

  • MoisturePlus contact lens solution as a source of acanthamoeba keratitis.

    abstract::Recently, it was suggested that the use of the Advanced Medical Optics Complete MoisturePlus multipurpose cleaning solution might be a risk factor for contracting Acanthamoeba keratitis, and the manufacturer voluntarily recalled it in May 2007. Polymerase chain reaction amplification and sequencing of a variable part ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318183a34b

    authors: Hasler S,Dedes W,Mathis A,Grimm F,Thiel MA

    更新日期:2009-02-01 00:00:00

  • Treatment of Acanthamoeba keratitis by corneal cross-linking.

    abstract:PURPOSE:To evaluate the efficacy of corneal cross-linking (CXL; riboflavin/ultraviolet A) as a simple therapy for Acanthamoeba keratitis. METHODS:Twenty rabbits were systemically anesthetized and the stroma of their right corneas was inoculated with a suspension of Acanthamoeba. Rabbits were divided into 2 groups: one...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31825cea99

    authors: Berra M,Galperín G,Boscaro G,Zarate J,Tau J,Chiaradia P,Berra A

    更新日期:2013-02-01 00:00:00

  • Localized amyloidosis of the cornea secondary to trichiasis: clinical course and pathogenesis.

    abstract:PURPOSE:To present four cases of localized corneal amyloidosis secondary to trichiasis and to discuss its pathogenesis. METHODS:Medical and pathologic records of four patients with corneal amyloidosis secondary to trichiasis were reviewed retrospectively. Two patients underwent trichiasis surgery and then lamellar ker...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/00003226-200307000-00020

    authors: Lin PY,Kao SC,Hsueh KF,Chen WY,Lee SM,Lee FL,Shiuh WM

    更新日期:2003-07-01 00:00:00

  • Toxicity of Intracameral Injection of Fourth-Generation Fluoroquinolones on the Corneal Endothelium.

    abstract:PURPOSE:The aim of this study was to compare the cellular susceptibility patterns and morphologic changes in the corneal endothelium associated with the use of fourth-generation fluoroquinolones. METHOD:Endothelial susceptibility was assessed through intracameral injection of besifloxacin, gatifloxacin, and moxifloxac...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000967

    authors: E Silva FB,Carrijo-Carvalho LC,Teixeira A,de Freitas D,Carvalho FR

    更新日期:2016-12-01 00:00:00

  • New Freeware for Image Analysis of Lissamine Green Conjunctival Staining.

    abstract:PURPOSE:Lissamine green (LG) is often used in addition to fluorescein to assess the severity of conjunctival damage in dry eye syndrome, which is graded manually. Our purpose was to describe an algorithm designed for image analysis of LG conjunctival staining. METHODS:Twenty pictures of patients suffering from dry eye...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002617

    authors: Courrier E,Renault D,Dib E,Urrea C,Kaspi M,Fournier C,Lépine T,Chiambaretta F,Hor G,He Z,Garcin T,Thuret G,Gain P

    更新日期:2020-12-18 00:00:00

  • Ocular manifestations after primary varicella infection.

    abstract:PURPOSE:To report a case of ocular manifestations after a primary varicella infection. METHODS:Review of the literature and a case report of a 10-year-old male patient with history of blurry vision and an enlarged pupil 2 months after a varicella infection. Examination revealed uveitis, interstitial keratitis, and int...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000224651.19837.6c

    authors: Fernández de Castro LE,Sarraf OA,Hawthorne KM,Solomon KD,Vroman DT

    更新日期:2006-08-01 00:00:00

  • Measurement of Corneal Biomechanical Properties in Diabetes Mellitus Using the Ocular Response Analyzer and the Corvis ST.

    abstract:PURPOSE:Hyperglycemia in diabetes mellitus (DM) might induce changes in corneal biomechanics. Therefore, biomechanical properties of the cornea were measured using the ocular response analyzer and the Corvis ST. METHODS:In the study, 35 eyes of 35 diabetic patients were included. After an ophthalmological examination,...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001879

    authors: Ramm L,Herber R,Spoerl E,Pillunat LE,Terai N

    更新日期:2019-05-01 00:00:00

  • Ocular morbidity associated with airbag deployment: a report of seven cases and a review of the literature.

    abstract:PURPOSE:To review ocular injuries secondary to airbag deployment that were seen in our institution and were reported in the literature. METHODS:Patients examined at our institution between 1997 and 2000 were evaluated for ocular injuries caused by airbags. A review of the medical literature using Medline was performed...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/00003226-200103000-00009

    authors: Ball DC,Bouchard CS

    更新日期:2001-03-01 00:00:00

  • Transient band-like keratopathy after treatment for seborrheic dermatitis.

    abstract:PURPOSE:To describe a case of transient band-like keratopathy after ocular exposure to fluocinonide cream and ketoconazole shampoo. DESIGN:Observational case report. RESULTS:A 40-year-old patient presented with acute pain, photophobia, lacrimation, and redness in 1 eye. The symptoms began while using fluocinonide cre...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000138854.33956.3d

    authors: Savage HI,Edgington B,Appel J

    更新日期:2005-04-01 00:00:00

  • Use of a Purpose-Built Impression Cytology Device for Gene Expression Quantification at the Ocular Surface Using Quantitative PCR and Droplet Digital PCR.

    abstract:PURPOSE:To describe an impression cytology (IC) technique using a purpose-built, sterile, EYEPRIM IC device that can be coupled with a TRIzol reagent-based RNA extraction protocol to yield sufficient RNA for gene expression analysis. METHODS:IC samples using the EYEPRIM device were collected from the bulbar conjunctiv...

    journal_title:Cornea

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/ICO.0000000000001792

    authors: Ganesalingam K,Ismail S,Craig JP,Sherwin T

    更新日期:2019-01-01 00:00:00

  • Recurrence of keratoconic pathology in penetrating keratoplasty buttons originally transplanted for keratoconus.

    abstract:PURPOSE:Study aimed to examine buttons removed from patients originally grafted for KC (group 1) for signs of recurrence at a cellular level and compare them with buttons removed from patients originally grafted for other conditions (group 2). The study further aimed to compare buttons from group 1 exhibiting high asti...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181967024

    authors: Brookes NH,Niederer RL,Hickey D,McGhee CN,Sherwin T

    更新日期:2009-07-01 00:00:00

  • Evaluation of Human Corneal Lenticule Quality After SMILE With Different Cap Thicknesses Using Scanning Electron Microscopy.

    abstract:PURPOSE:To evaluate the surface characteristics of lenticules created by small-incision lenticule extraction (SMILE) with different cap thicknesses. METHODS:This prospective study included 20 consecutive patients who underwent bilateral SMILE. Surface regularity of the extracted corneal lenticule was analyzed using sc...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001404

    authors: Weng S,Liu M,Yang X,Liu F,Zhou Y,Lin H,Liu Q

    更新日期:2018-01-01 00:00:00

  • Vortex keratopathy of the corneal graft.

    abstract::We examined the surface epithelium of 30 eyes with color specular microscopy at 3-month intervals 1-18 months following penetrating keratoplasty. At least three examinations were performed on most eyes. We found a vortex keratopathy to be present in 70% of these eyes. In nine eyes, this vortex pattern was present at e...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199103000-00001

    authors: Mathers WD,Lemp MA

    更新日期:1991-03-01 00:00:00

  • Corneal endothelial cell damage after lens extraction using the fluid-based system compared to ultrasound phacoemulsification in human cadaver eyes.

    abstract:PURPOSE:To compare the endothelial cell damage after lens removal using a fluid-based system to conventional ultrasound. METHODS:Twenty human cadaver eyes were randomized to undergo phacoemulsification using either a fluid-based system or conventional ultrasound. After surgery, each corneoscleral button was removed, s...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000130184.56514.51

    authors: Sandoval HP,Al Sarraf O,Vroman DT,Solomon KD

    更新日期:2004-10-01 00:00:00

  • In Situ Corneal Cross-Linking for Recurrent Corneal Melting After Boston Type 1 Keratoprosthesis.

    abstract:PURPOSE:To present a new treatment modality for recurrent corneal melting in a patient with a Boston type I keratoprosthesis (B-KPro) including in situ corneal cross-linking (CXL) and lamellar keratoplasty (LKP) as combined treatment. METHODS:Case report. RESULTS:Our report concerns a 27-year-old man whose case histo...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000830

    authors: Tóth G,Bucher F,Siebelmann S,Bachmann B,Hermann M,Szentmáry N,Nagy ZZ,Cursiefen C

    更新日期:2016-06-01 00:00:00

  • Comparative Evaluation of Central Corneal Thickness in Cross-Linked Keratoconic Eyes.

    abstract:PURPOSE:To compare the central corneal thickness (CCT) measurements measured by using the Pentacam Scheimpflug system with the CCT measured using ultrasound pachymetry (UP) and to compare the compatibility between the methods in normal, keratoconic, and cross-linked keratoconic corneas. METHODS:The study included 50 e...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002339

    authors: Kosekahya P,Koc M,Yalcinsoy KO,Kocabas DO,Toker MI

    更新日期:2020-09-01 00:00:00

  • The effect of age on the corneal subbasal nerve plexus.

    abstract:PURPOSE:To measure subbasal nerve density and orientation in normal human corneas across a broad age range. METHODS:Sixty-five normal corneas of 65 subjects were examined by using tandem scanning confocal microscopy. Ages of subjects ranged from 15 to 79 years (mean 46 +/- 19 years), with 5 subjects from each hemideca...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000154387.51355.39

    authors: Erie JC,McLaren JW,Hodge DO,Bourne WM

    更新日期:2005-08-01 00:00:00