Measurement of Corneal Biomechanical Properties in Diabetes Mellitus Using the Ocular Response Analyzer and the Corvis ST.

Abstract:

PURPOSE:Hyperglycemia in diabetes mellitus (DM) might induce changes in corneal biomechanics. Therefore, biomechanical properties of the cornea were measured using the ocular response analyzer and the Corvis ST. METHODS:In the study, 35 eyes of 35 diabetic patients were included. After an ophthalmological examination, measurements with the ocular response analyzer and the Corvis ST were taken. Additionally, biometry and corneal topography were performed and HbA1c values were collected. Results were compared to an age-, pachymetry- and intraocular pressure-matched group of 35 healthy subjects. RESULTS:Mean age (67.6 ± 10.3; 64.1 ± 8.3 years), intraocular pressure (13.4 ± 2.9; 12.8 ± 2.8 mm Hg), and central corneal thickness (556.4 ± 31.7; 548.6 ± 32.9 μm) were not significantly different between the groups (P > 0.05). In DM, the corneal hysteresis (CH) and the corneal resistance factor (CRF) were increased (CH: 10.8 ± 2 vs. 9.4 ± 1.6, P = 0.002; CRF: 10.6 ± 2.1 vs. 9.6 ± 1.5, P = 0.022). Also, most dynamic corneal response parameters showed significant differences. Beside others, A1 and A2 deflection amplitudes were increased (P < 0.001) and highest concavity and A2 time were extended (P < 0.001 and 0.007) in DM. According to current HbA1c value, DM was classified as controlled (≤7%) and poorly controlled (>7%) and significant biomechanical differences were measured between both groups. CONCLUSIONS:In DM, significant changes in corneal biomechanical properties were detectable. In patients, CH and CRF were increased and most dynamic corneal response parameters were different compared to healthy subjects.

journal_name

Cornea

journal_title

Cornea

authors

Ramm L,Herber R,Spoerl E,Pillunat LE,Terai N

doi

10.1097/ICO.0000000000001879

subject

Has Abstract

pub_date

2019-05-01 00:00:00

pages

595-599

issue

5

eissn

0277-3740

issn

1536-4798

journal_volume

38

pub_type

杂志文章

相关文献

CORNEA文献大全
  • Herpes simplex virus genome quantification in two patients who developed herpetic epithelial keratitis during treatment with antiglaucoma medications.

    abstract:PURPOSE:We quantitated herpes simplex virus (HSV) DNA in tear film obtained from 2 patients who developed herpetic epithelial keratitis (HEK) during treatment with latanoprost and a beta-blocker. METHODS:The patient in case 1 is a 77-year-old woman with bilateral open-angle glaucoma who had been treated with latanopro...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200403000-00004

    authors: Deai T,Fukuda M,Hibino T,Higaki S,Hayashi K,Shimomura Y

    更新日期:2004-03-01 00:00:00

  • OCT-derived comparison of corneal thickness distribution and asymmetry differences between normal and keratoconic eyes.

    abstract:PURPOSE:The aim of this study was to investigate the corneal thickness asymmetry indices in a large pool of patients with keratoconus derived using anterior segment optical coherence tomography (AS-OCT) in comparison with established Scheimpflug imaging-derived keratoconus classification indices. METHODS:Six specific ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000275

    authors: Kanellopoulos AJ,Asimellis G

    更新日期:2014-12-01 00:00:00

  • Association Between Sleep Quality, Mood Status, and Ocular Surface Characteristics in Patients With Dry Eye Disease.

    abstract:PURPOSE:To evaluate sleep and mood status in patients with dry eye disease (DED) and analyze the association between sleep quality, mood status, and ocular surface characteristics. METHODS:Consecutive patients with DED (N = 106) and age- and sex-matched healthy controls (N = 50) were enrolled. Tear fluid break up time...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001854

    authors: Wu M,Liu X,Han J,Shao T,Wang Y

    更新日期:2019-03-01 00:00:00

  • New-onset herpes simplex virus keratitis after cataract surgery.

    abstract::We report the case of a 34-year-old man who had uncomplicated cataract surgery in his left eye. Medical history was significant for atopic dermatitis, requiring oral immunosuppressive medications. Two days after the surgery, the patient presented with pain, photophobia, decreased vision, and a small corneal abrasion. ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318182262c

    authors: Patel NN,Teng CC,Sperber LT,Dodick JM

    更新日期:2009-01-01 00:00:00

  • Ocular microfluctuations and videokeratoscopy.

    abstract:PURPOSE:We aimed to minimize the effect of ocular microfluctuations during videokeratoscopy to improve the qualitative and quantitative analysis of corneal topography. METHODS:A technique was developed to measure the tilt, displacement, and cyclotorsion in multiple videokeratographs from the same cornea. This informat...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200205000-00003

    authors: Buehren T,Lee BJ,Collins MJ,Iskander DR

    更新日期:2002-05-01 00:00:00

  • Alkali Burn Over a LASIK Flap.

    abstract:PURPOSE:To describe the management and outcome of an ocular surface alkali burn in the setting of previous laser in situ keratomileusis (LASIK). METHODS:This is a case report and review of relevant literature. RESULTS:A 25-year-old man with a history of LASIK presented 4 weeks after a sodium hydroxide splash to his l...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002604

    authors: Witsberger EM,Patel SV

    更新日期:2020-12-03 00:00:00

  • Healing rate of corneal erosions: comparison of the effect of chloramphenicol eye drops and ointment and high-concentration hyaluronic acid in an animal model.

    abstract:PURPOSE:The aim of this study was to compare the effect of chloramphenicol eye drops or ointment, high-concentration hyaluronic acid, or no treatment on reepithelialization of corneal erosions in an experimental model. METHODS:Uniform 6-mm corneal erosions were created in 23 rabbit eyes. The rabbits were randomized to...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000215

    authors: Barequet IS,Harizman N,Ziv H,Rosner M

    更新日期:2014-10-01 00:00:00

  • Clinical, histopathologic, and ultrastructural characteristics of BIGH3(TGFBI) amyloid corneal dystrophies are supportive of the existence of a new type of LCD: the LCDi.

    abstract:PURPOSE:To assess the morphologic differences of three types of lattice corneal dystrophies (LCDs) from histologic, immunohistochemical, and ultrastructural studies. METHODS:Corneas from three patients, one LCD1, one His626Arg-LCD, and one LCD3A were processed for Congo red, betaig-h3(541-564) antibodies immunostainin...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200207000-00006

    authors: Schmitt-Bernard CF,Schneider C,Argilés A

    更新日期:2002-07-01 00:00:00

  • Psychometric Properties of the Keratoconus Outcomes Research Questionnaire: A Save Sight Keratoconus Registry Study.

    abstract:PURPOSE:The aim of this study was to evaluate the psychometric properties of the Keratoconus Outcomes Research Questionnaire (KORQ) in patients enrolled in the Save Sight Keratoconus Registry. METHODS:A cross-sectional study was conducted utilizing prospectively collected web-based registry data. The psychometric prop...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002169

    authors: Kandel H,Pesudovs K,Ferdi A,Mills R,Chen JY,Watson A,Poon A,Downie LE,Watson SL

    更新日期:2020-03-01 00:00:00

  • Diagnosis of subclinical keratoconus using posterior elevation measured with 2 different methods.

    abstract:PURPOSE:To compare the efficacy of posterior corneal elevation, measured by 2 methods, in discriminating subclinical keratoconus from normal corneas. METHODS:In 30 consecutive patients with subclinical keratoconus, and 37 candidates for refractive surgery, posterior corneal elevation was measured using Pentacam's rota...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3182854774

    authors: de Sanctis U,Aragno V,Dalmasso P,Brusasco L,Grignolo F

    更新日期:2013-07-01 00:00:00

  • Case Report: Suspected Donor Transmission of Acanthamoeba Keratitis After Deep Anterior Lamellar Keratoplasty.

    abstract:PURPOSE:In our report, we present a suspected case of donor-derived Acanthamoeba keratitis after deep anterior lamellar keratoplasty. To the authors' knowledge, there have been no confirmed cases of Acanthamoeba keratitis transmission through corneal transplantation. METHODS:Deep anterior lamellar keratoplasty was per...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002517

    authors: Ward MS,Bontu S,Martheswaran T,Mamalis N,Moshirfar M

    更新日期:2020-09-16 00:00:00

  • Intraoperative mitomycin C and corneal endothelium after pterygium surgery.

    abstract:PURPOSE:To determine the effect of mitomycin C (MMC) on the corneal endothelium after primary pterygium surgery. METHODS:This prospective, interventional, nonrandomized, observer-masked study included 46 consecutive patients (51 eyes) with primary pterygium. The bare sclera technique with 1-minute application of 0.02%...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181a3c548

    authors: Pérez-Rico C,Benítez-Herreros J,Montes-Mollón MA,Germain F,Castro-Rebollo M,Gómez-SanGil Y,Paz-Moreno J,Teus MA

    更新日期:2009-12-01 00:00:00

  • Morphology of the Corneal Limbus Following Standard and Accelerated Corneal Collagen Cross-Linking (9 mW/cm2) for Keratoconus.

    abstract:PURPOSE:To evaluate the morphological features of the corneal limbus as measured by in vivo confocal microscopy (IVCM) following standard and accelerated corneal collagen cross-linking (CXL) for keratoconus. METHODS:Patients with progressive keratoconus scheduled to undergo standard CXL (group 1; 31 patients, 3 mW/cm,...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001029

    authors: Uçakhan ÖÖ,Bayraktutar B

    更新日期:2017-01-01 00:00:00

  • Outcomes of Penetrating and Lamellar Corneal Patch Grafts.

    abstract:PURPOSE:To report the indications, long-term structural and functional outcomes, and prognostic factors for the success of penetrating and lamellar corneal patch grafts. METHODS:This is a retrospective analysis of 49 patients who underwent the corneal patch graft procedure over 8 years. The baseline, preoperative, and...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002529

    authors: Sharma S,Rathi A,Murthy SI,Trivedi M,Patel C,Mohamed A,Chaurasia S

    更新日期:2020-09-29 00:00:00

  • Topical treatment with 1% cyclosporine for subepithelial infiltrates secondary to adenoviral keratoconjunctivitis.

    abstract:PURPOSE:To evaluate the treatment with topical 1% cyclosporine A (CsA) in patients with subepithelial corneal infiltrates (SEIs). METHODS:We retrospectively reviewed the records of 9 patients (12 eyes) before and after the treatment with CsA 1% eyedrops twice daily. All patients had been treated with topical corticost...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181c33034

    authors: Levinger E,Slomovic A,Sansanayudh W,Bahar I,Slomovic AR

    更新日期:2010-06-01 00:00:00

  • Modified deep anterior lamellar keratoplasty in the management of small and large epithelialized descemetoceles.

    abstract:PURPOSE:Descemetocele is a severe complication of corneal ulceration associated with a high risk of perforation. We describe a modified air-assisted deep anterior lamellar keratoplasty (DALK) technique for the surgical management of small and large epithelialized descemetoceles. METHODS:Two representative cases are pr...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3182031c81

    authors: Gabison EE,Doan S,Catanese M,Chastang P,Ben M'hamed M,Cochereau I

    更新日期:2011-10-01 00:00:00

  • Peripheral Pneumatic Dissection and Scar Peeling to Complete Deep Anterior Lamellar Keratoplasty in Eyes With Healed Hydrops.

    abstract:PURPOSE:To describe a surgical technique to achieve the desired plane during deep anterior lamellar keratoplasty (DALK) in eyes with Descemet membrane (DM) tears due to previous hydrops. METHODS:This was a prospective, consecutive, interventional case series of DALK in 12 keratoconic eyes with healed hydrops. Dissecti...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001864

    authors: Goweida MB,Sobhy M,Seifelnasr M,Liu C

    更新日期:2019-04-01 00:00:00

  • On the morphology of cells of posterior cornea in the iridocorneal endothelial syndrome.

    abstract::The iridocorneal endothelial (ICE) syndrome is potentially a blinding condition as a result of glaucoma and/or corneal decompensation. The basic pathology seems to be in the corneal endothelium, which many studies confirm takes on a characteristic slit lamp appearance of hammered silver and image reversal with the spe...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199105000-00009

    authors: Sherrard ES,Frangoulis MA,Muir MG

    更新日期:1991-05-01 00:00:00

  • Low Recurrence Rate of Pterygium After Excision With Conjunctival Limbal Autograft: A Retrospective Study With Long-Term Follow-Up.

    abstract:PURPOSE:Pterygium excision with conjunctival limbal autograft (CLAG) has been used successfully for prevention of pterygium recurrence. However, long-term follow-up data in the literature are lacking regarding CLAG. METHODS:Retrospective chart review and standard statistical analysis were performed. The records of 289...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000597

    authors: Masters JS,Harris DJ Jr

    更新日期:2015-12-01 00:00:00

  • Corneal involvement in congenital aniridia.

    abstract:PURPOSE:The purpose of this research is 2-fold. First of all, the level of keratopathy development in patients with congenital aniridia is studied. In addition, a correlation between the effects of ocular surgery on the severity of keratopathy is made. METHODS:A thorough search for the total number of patients with an...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181d20493

    authors: Edén U,Riise R,Tornqvist K

    更新日期:2010-10-01 00:00:00

  • Endothelial keratoplasty: the influence of insertion techniques and incision size on donor endothelial survival.

    abstract:PURPOSE:To determine the acute endothelial cell damage from trephination and tissue insertion in endothelial keratoplasty (EK) surgery. The influence of insertion technique (forceps insertion vs "pull-through" insertion) of donor tissue and incision size (3 vs 5 mm length) was assessed. METHODS:Forty precut 8.-mm-diam...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318182a4d3

    authors: Terry MA,Saad HA,Shamie N,Chen ES,Phillips PM,Friend DJ,Holiman JD,Stoeger C

    更新日期:2009-01-01 00:00:00

  • Corneoscleral epithelial cysts: evidence of developmental etiology.

    abstract:PURPOSE:To describe the clinical features, histopathology, surgical management and possible etiopathogenesis of corneoscleral epithelial cysts. METHODS:Three patients with corneoscleral epithelial cysts underwent surgical ablation of the cysts. Material obtained during surgery was subjected to histopathologic analysis...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199807000-00018

    authors: Rao SK,Fogla R,Biswas J,Padmanabhan P

    更新日期:1998-07-01 00:00:00

  • Correlation between clinical in vivo confocal microscopic and ex vivo histopathologic findings of Salzmann nodular degeneration.

    abstract:PURPOSE:To report clinical, in vivo confocal microscopy and ex vivo histopathologic findings of Salzmann nodular degeneration (SND). METHODS:A 48-year-old woman with symptoms of ocular irritation and decreased visual acuity caused by SND in both eyes was treated by corneal scraping and phototherapeutic keratectomy (PT...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000214215.75496.a5

    authors: Meltendorf C,Bühren J,Bug R,Ohrloff C,Kohnen T

    更新日期:2006-07-01 00:00:00

  • Recovery of the Corneal Stroma Associated With Rapid Reepithelialization Induced by the Fibronectin-Derived Peptide PHSRN in 2 Cases of Corneal Perforation Due to a Persistent Epithelial Defect.

    abstract:PURPOSE:To report 2 cases of corneal perforation associated with a persistent epithelial defect (PED), which were treated with eye drops containing the fibronectin-derived peptide PHSRN (Pro-His-Ser-Arg-Asn). METHODS:A 67-year-old man and a 58-year-old man presented with corneal perforation associated with a PED cause...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000592

    authors: Morita Y,Morishige N,Yamada N,Ohta M,Sonoda KH,Nishida T

    更新日期:2015-11-01 00:00:00

  • Vortex keratopathy of the corneal graft.

    abstract::We examined the surface epithelium of 30 eyes with color specular microscopy at 3-month intervals 1-18 months following penetrating keratoplasty. At least three examinations were performed on most eyes. We found a vortex keratopathy to be present in 70% of these eyes. In nine eyes, this vortex pattern was present at e...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199103000-00001

    authors: Mathers WD,Lemp MA

    更新日期:1991-03-01 00:00:00

  • Combination topical therapy for conjunctival primary acquired melanosis with atypia and periocular lentigo maligna.

    abstract:PURPOSE:To report the case of a patient who initially presented with primary acquired melanosis (PAM) without atypia of the conjunctiva and later developed lentigo maligna of the eyelids and PAM with atypia of the conjunctiva. We illustrate the utility of combination topical therapy with adjunctive cryotherapy to treat...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000277

    authors: Bratton EM,Knutsen-Larson S,Durairaj VD,Gregory DG,Mellette JR

    更新日期:2015-01-01 00:00:00

  • Comparison of Topical Application of TSG-6, Cyclosporine, and Prednisolone for Treating Dry Eye.

    abstract:PURPOSE:To compare the therapeutic effects of topical tumor necrosis factor (TNF)-α-stimulated gene/protein-6 (TSG-6) with those of cyclosporine and prednisolone eye drops in NOD.B10.H2 mice, a model for inflammation-mediated dry eye. METHODS:The 12-week-old NOD.B10.H2 mice were topically administered recombinant TSG-...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000756

    authors: Kim YJ,Ryu JS,Park SY,Lee HJ,Ko JH,Kim MK,Wee WR,Oh JY

    更新日期:2016-04-01 00:00:00

  • Preliminary in vitro evaluation of 2-octyl cyanoacrylate (Dermabond) to seal corneal incisions.

    abstract:OBJECTIVE:To compare the efficacy of Dermabond with conventional nylon sutures for sealing linear corneal incisions. METHODS:A keratome knife was used to create a 4-mm full-thickness linear corneal incision anterior to the limbal arcade in 20 fresh pig eyes. The incision was sealed with Dermabond tissue adhesive or cl...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000159734.75672.c4

    authors: Leung GY,Peponis V,Varnell ED,Lam DS,Kaufman HE

    更新日期:2005-11-01 00:00:00

  • Characterization of Corneal Donor Tissue Lesions by Anterior Segment Optical Coherence Tomography Compared With Eye Bank Technician Slit-Lamp Examination.

    abstract:PURPOSE:To compare anterior segment spectral-domain optical coherence tomography (OCT) with eye bank technician slit-lamp examination (SLE) in characterizing lesions in donor corneas. METHODS:Twenty-nine donor corneas identified by eye bank technicians to have opacities or lesions potentially representing pathologic f...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001700

    authors: Hsu ST,Perry I,Botsay S,Ko N,Stinnett SS,Kuo AN,Shieh C

    更新日期:2018-10-01 00:00:00

  • Efficacy of Omega-3 Fatty Acid Supplementation for Treatment of Dry Eye Disease: A Meta-Analysis of Randomized Clinical Trials.

    abstract:PURPOSE:To assess whether omega-3 fatty acid (FA) supplementation is more efficacious than placebo in amelioration of signs and symptoms of dry eye disease. METHODS:We performed a systematic literature search in PubMed, Scopus, Web of Science, and Cochrane Central Register of Controlled Trials databases. We included r...

    journal_title:Cornea

    pub_type: 杂志文章,meta分析

    doi:10.1097/ICO.0000000000001884

    authors: Giannaccare G,Pellegrini M,Sebastiani S,Bernabei F,Roda M,Taroni L,Versura P,Campos EC

    更新日期:2019-05-01 00:00:00