Microsporidial stromal keratitis masquerading as acute graft rejection.

Abstract:

PURPOSE:To describe the clinical features, disease course, management, and visual outcome of stromal microsporidial keratitis involving the corneal graft in an immunocompetent patient. METHODS:Case report. RESULTS:We report the case of a 21-year-old immunocompetent woman, who underwent penetrating keratoplasty for advanced keratoconus in her right eye and presented with features of acute graft rejection after 15 months. Standard treatment using topical and systemic steroids failed to reverse the graft rejection. A regraft was performed in that eye. Histopathology of the donor corneal button revealed microsporidiosis involving the deep stroma. CONCLUSIONS:Microsporidiosis is rarely encountered in a corneal graft and masquerades as acute graft rejection. Histopathology could help in making a final diagnosis.

journal_name

Cornea

journal_title

Cornea

authors

Pradhan S,Mascarenhas J,Srinivasan M

doi

10.1097/ICO.0000000000000337

subject

Has Abstract

pub_date

2015-03-01 00:00:00

pages

353-4

issue

3

eissn

0277-3740

issn

1536-4798

journal_volume

34

pub_type

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