Transplantation of cultured human corneal endothelial cells.

abstract：PURPOSE:To develop a rat model of chronic Acanthamoeba polyphaga keratitis suitable for pharmacologic assessment of therapeutic agents. METHODS:An A. polyphaga isolate (ATCC #50495) was grown in peptone-yeast extract-glucose medium. Five-weeks-old, Sprague-Dawley male rats were injected with 10(3) or 10(4) trophozoite...

journal_title：Cornea

authors： Vasseneix C,Gargala G,François A,Hellot MF,Duclos C,Muraine M,Benichou J,Ballet JJ,Brasseur G,Favennec L

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:To identify whether histopathologic presence of neovascularization is predictive for allograft failure following penetrating keratoplasty for herpes simplex virus (HSV) keratitis. METHODS:Retrospective, interventional case series of 62 consecutive patients with HSV keratitis who underwent penetrating keratopla...

journal_title：Cornea

authors： Garcia DD,Shtein RM,Musch DC,Elner VM

更新日期：2009-10-01 00:00:00

abstract：PURPOSE:To assess the efficacy of using a bandage contact lens (BCL) for 3 months for recurrent corneal erosions (RCE) to facilitate epithelial adhesion. METHODS:Retrospective study of patients presented to the Casey Eye Institute (Portland, OR) with RCE after failing at least 6 weeks of medical lubrication therapy. S...

journal_title：Cornea

authors： Fraunfelder FW,Cabezas M

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:To determine the effect of mitomycin C (MMC) on the corneal endothelium after primary pterygium surgery. METHODS:This prospective, interventional, nonrandomized, observer-masked study included 46 consecutive patients (51 eyes) with primary pterygium. The bare sclera technique with 1-minute application of 0.02%...

journal_title：Cornea

authors： Pérez-Rico C,Benítez-Herreros J,Montes-Mollón MA,Germain F,Castro-Rebollo M,Gómez-SanGil Y,Paz-Moreno J,Teus MA

更新日期：2009-12-01 00:00:00

abstract：PURPOSE:Tear secretion from the main lacrimal gland (LG) is mainly regulated by parasympathetic nerves. We performed several innervation studies to investigate lacrimation. METHODS:In male rabbits, we performed a retrograde dye-tracing study of LG innervation, evaluated preganglionic parasympathetic denervation, and a...

journal_title：Cornea

authors： Toshida H,Suto C

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:To assess the endothelial cell loss after cataract extraction using a fluid-based system and compare it with conventional ultrasound. METHODS:A total of 46 eyes of 23 patients with up to 3+ bilateral cataract were included. The first eye was randomized to either fluid-based system or conventional ultrasound, a...

journal_title：Cornea

authors： Sandoval HP,de Castro LE,Vroman DT,Solomon KD

更新日期：2006-10-01 00:00:00

abstract：PURPOSE:To study the possible changes in Scheimpflug corneal densitometry 6 months after mitomycin C-augmented trabeculectomy and to compare these measurements with healthy controls. METHODS:Corneal densitometry was monitored with the Pentacam HR3 before and 6 months after first-time uncomplicated mitomycin C-augmente...

journal_title：Cornea

authors： Pillunat KR,Orphal J,Haase M,Pillunat LE,Herber R

更新日期：2020-07-27 00:00:00

abstract：:Corneal photorefractive surgery is currently performed by ablation of corneal stroma under the stromal flap. A stromal flap is created using a femtosecond (FS) laser or mechanical microkeratome, although the FS laser procedure is considered safer and more accurate. This review assesses and compares the use of FS laser...

journal_title：Cornea

authors： Sumioka T,Miyamoto T,Takatsuki R,Okada Y,Yamanaka O,Saika S

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:To review the clinical course, treatment, and visual outcomes of keratitis with endophthalmitis caused by the filamentary fungus Fusarium. METHOD:One hundred fifty-nine cases of Fusarium keratitis at Bascom Palmer Eye Institute between January 1, 1987 and August 21, 2000 were reviewed. Ten patients with cultur...

journal_title：Cornea

authors： Dursun D,Fernandez V,Miller D,Alfonso EC

更新日期：2003-05-01 00:00:00

abstract：PURPOSE:To report on surgical reduction of oculodermal melanosis in 6 patients presenting with severe episcleral pigmentation. METHODS:After informed consent was obtained, surgical reduction of ocular pigmentation with ocular dermal melanosis was performed on 3 children, 2 girls and 1 boy male, who were cosmetically h...

journal_title：Cornea

authors： Kim TI,Yoon J,Choi J,Tchah H

更新日期：2005-05-01 00:00:00

abstract：PURPOSE:To determine whether autologous Descemet stripping endothelial keratoplasty is technically feasible and whether it eliminates the risk of endothelial rejection in "only eyes" at high risk of immunological rejection. METHODS:This is a prospective observational interventional study from 2016 to 2018 with a 24-mo...

journal_title：Cornea

authors： Myerscough J,Friehmann A,Bovone C,Busin M

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:To report the clinical, histopathologic, and confocal findings of corneal siderosis. METHODS:A 35-year-old man presented after a car battery explosion with diffuse left corneal anterior stromal pigment deposition and an intraocular metallic foreign body of the left iris. The corneal pigment was analyzed by con...

journal_title：Cornea

authors： Witherspoon SR,Hogan RN,Petroll WM,Mootha VV

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:Corneal inflammation in overnight contact lens (CL) wear is not fully understood. We designed a masked study to examine the impact of overnight CL wear on clinical variables in subjects who had previously experienced corneal inflammatory disease. METHODS:Forty-four subjects were entered into the study: Nine su...

journal_title：Cornea

authors： Stapleton F,Ramachandran L,Sweeney DF,Rao G,Holden BA

更新日期：2003-07-01 00:00:00

abstract：:Two cases of intracorneal hemorrhage developing as a complication of aphakic contact lens use are reported. Patient 1 had a penetrating keratoplasty to restore vision and therefore the histologic examination could be performed on the corneal button. In patient 2 the contact lens use was discontinued with partial resol...

journal_title：Cornea

authors： al-Hussaini AK,Friedlander MH,Karcioglu ZA

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:To assess the effects of corneal collagen cross-linking (CXL) on contrast sensitivity (CS), visual acuity, and corneal topography investigating possible predictors of efficacy. METHODS:Sixty-eight eyes of 34 patients with progressive keratoconus were enrolled in this prospective study. CXL was performed in one...

journal_title：Cornea

authors： Lamy R,Netto CF,Reis RG,Procopio B,Porco TC,Stewart JM,Dantas AM,Moraes HV Jr

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:The aim of this study was to estimate both the direct and indirect annual cost of managing dry eye disease (DED) in the United States from a societal and a payer's perspective. METHODS:A decision analytic model was developed to estimate the annual cost for managing a cohort of patients with dry eye with differ...

journal_title：Cornea

authors： Yu J,Asche CV,Fairchild CJ

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:To compare paired human corneas after storage at 4 degrees C in Chen medium (CM) and Optisol-GS medium (OM) for 7, 10, 14, and 21 days. METHODS:One cornea of each pair from nine human donors was randomly stored in either CM or OM, with its mate cornea stored in the other medium. Three pairs of corneas were sto...

journal_title：Cornea

authors： Nelson LR,Hodge DO,Bourne WM

更新日期：2000-11-01 00:00:00

abstract：PURPOSE:To determine how ocular surface epithelium adjusts to an increase in cell replication after treatment with the opioid antagonist naltrexone (NTX). METHODS:Adult male rats were given twice daily injections of 30 mg/kg NTX or vehicle for 7 days. Outcomes of NTX administration included DNA synthesis (monitored wi...

journal_title：Cornea

authors： Zagon IS,Sassani JW,McLaughlin PJ

更新日期：2006-08-01 00:00:00

abstract：PURPOSE:To report spontaneous corneal perforation as a presenting sign of unilateral Terrien marginal degeneration in a young adult. METHODS:A 19-year-old woman presented with sudden loss of vision in her left eye of 1-day duration. Examination revealed superior corneal thinning with superficial vascularization and se...

journal_title：Cornea

authors： Srinivasan S,Murphy CC,Fisher AC,Freeman LB,Kaye SB

更新日期：2006-09-01 00:00:00

abstract：PURPOSE:To describe an invasive spindle cell carcinoma of the conjunctiva managed by full-thickness eye wall resection. METHODS:A 51-year-old man developed a conjunctival mass that was excised and proved to be a spindle cell carcinoma. A tumor recurrence 20 months later was evaluated by ultrasound biomicroscopy (UBM) ...

journal_title：Cornea

authors： Shields JA,Eagle RC,Marr BP,Shields CL,Grossniklaus HE,Stulting RD

更新日期：2007-09-01 00:00:00

abstract：PURPOSE:To investigate the feasibility of using Brillouin microscopy for assessment of corneal edema in patients with Fuchs endothelial corneal dystrophy (FECD). Brillouin microscopy analyzes the frequency shift of light inelastically scattered by naturally occurring acoustic waves in a small volume of tissue. The resu...

journal_title：Cornea

authors： Eltony AM,Clouser F,Shao P,Pineda R 2nd,Yun SH

更新日期：2020-02-01 00:00:00

abstract：:Posterior polymorphous corneal dystrophy (PPD) is a rare bilateral, autosomal-dominant disease. The presence of the epitheliumlike endothelium and the thickening of Descemet's membrane by the posterior collagenous layer (PCL) has been reported in the majority of published cases. Reepithelialization of the posterior co...

journal_title：Cornea

authors： Sekundo W,Lee WR,Aitken DA,Kirkness CM

更新日期：1994-11-01 00:00:00

abstract：:Here we report a new method for image analysis of the corneal stroma. To obtain the biometric characteristics of a given area, we perform three different treatments of the same image. These automated predictions closely match each parameter (length, surface area, etc.), as measured manually by a "blind investigator." ...

journal_title：Cornea

authors： Karpouzas I,Durand JP,Keller N,Savoldelli M,Pouliquen Y

更新日期：1991-07-01 00:00:00

abstract：:The following is a case report of a 61-year-old woman with a 10-year history of pemphigus vulgaris, successfully treated with steroids and cytotoxic agents. The patient developed severe herpes zoster ophthalmicus, complicated by a staph-indolent corneal ulcer. This case illustrates several of the many unfortunate opht...

journal_title：Cornea

authors： Webb RM,Duke MA

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:To report the outcome and the reversibility of refractive outcomes after intrastromal corneal ring segment (ICRS) explantation in patients with keratoconus treated with ICRS implantation and same-day collagen crosslinking (CXL). METHODS:This is a retrospective review of ICRS explantation in 3 eyes of 3 patient...

journal_title：Cornea

authors： Yeung SN,Lichtinger A,Ku JY,Kim P,Low SA,Rootman DS

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:To identify potential donor, recipient, surgical, and postoperative factors that may influence survival and visual outcome of penetrating keratoplasty (PKP). METHODS:As part of a prospective longitudinal study, the electronic records of the New Zealand National Eye Bank were analyzed for the 10-year period fro...

journal_title：Cornea

authors： Patel HY,Ormonde S,Brookes NH,Moffatt SL,Sherwin T,Pendergrast DG,McGhee CN

更新日期：2011-07-01 00:00:00

abstract：PURPOSE:To report a case of direct contact xylene-related vacuolar keratopathy. METHODS:Interventional case report and review of the literature. RESULTS:Xylene keratopathy is a distinct clinical entity characterized by significantly decreased visual acuity, increased corneal thickness, and the presence of corneal epi...

journal_title：Cornea

authors： Trujillo F,Dang D,Starck T

更新日期：2003-01-01 00:00:00

abstract：PURPOSE:To review ocular injuries secondary to airbag deployment that were seen in our institution and were reported in the literature. METHODS:Patients examined at our institution between 1997 and 2000 were evaluated for ocular injuries caused by airbags. A review of the medical literature using Medline was performed...

journal_title：Cornea

authors： Ball DC,Bouchard CS

更新日期：2001-03-01 00:00:00

abstract：PURPOSE:To report the use of intracameral amphotericin B in the management of deep keratomycosis. METHODS:Four patients with deep keratomycosis unresponsive to conventional medical treatment underwent repeated intracameral injections of 5 microg amphotericin B in 0.1 mL 5% dextrose through a paracentesis. Three to 13 ...

journal_title：Cornea

authors： Kuriakose T,Kothari M,Paul P,Jacob P,Thomas R

更新日期：2002-10-01 00:00:00

abstract：PURPOSE:To assess the surgical and clinical outcomes of anterior lamellar keratoplasty using anterior corneal buttons from Descemet stripping automated endothelial keratoplasty (DSAEK) donor tissue. METHODS:Retrospective data from 8 patients with unilateral limbal dermoids, treated between February 2011 and January 20...

journal_title：Cornea

authors： Wu KI,Chu HS,Pai AS,Hou YC,Lin SY,Chen WL,Hu FR

更新日期：2017-01-01 00:00:00