Slit-lamp, confocal, and light microscopic findings of corneal siderosis.

Abstract:

PURPOSE:To report the clinical, histopathologic, and confocal findings of corneal siderosis. METHODS:A 35-year-old man presented after a car battery explosion with diffuse left corneal anterior stromal pigment deposition and an intraocular metallic foreign body of the left iris. The corneal pigment was analyzed by confocal microscopy and a lamellar corneal biopsy. RESULTS:Confocal microscopy showed the pigment to be highly reflective material in the corneal stroma with greatest density anteriorly. Histologic examination revealed the pigment to be iron with a diagnosis consistent with corneal siderosis. CONCLUSIONS:Corneal biopsy with Prussian blue established siderosis as the etiology of corneal pigmentation. A short delay in the removal of the foreign body contributed to the development of siderosis. The location of the foreign body on the iris may account for the predominant corneal involvement and relative sparing of the retina. Confocal microscopy may be useful in the evaluation of corneal siderosis.

journal_name

Cornea

journal_title

Cornea

authors

Witherspoon SR,Hogan RN,Petroll WM,Mootha VV

doi

10.1097/ICO.0b013e318145330b

subject

Has Abstract

pub_date

2007-12-01 00:00:00

pages

1270-2

issue

10

eissn

0277-3740

issn

1536-4798

pii

00003226-200712000-00023

journal_volume

26

pub_type

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