Association Between Dyslipidemia and Dry Eye Syndrome Among the Korean Middle-Aged Population.

Abstract:

PURPOSE:Dry eye syndrome (DES) is a common eye disease caused by tear deficiency or excessive tear evaporation. Because the tear film layers play a major role in the pathogenesis of the evaporative dry eye, some previous articles have suggested the possible mechanism of dyslipidemia and DES. However, the previous results were inconsistent and few studies were conducted to find the independent relationship between dyslipidemia and DES. Therefore, we investigated the association of dyslipidemia with DES in middle-aged Korean adults. METHODS:This study was conducted on 2272 participants (854 men and 1418 women) enrolled in the Study Group for Environmental Eye Disease (2013-2017) after excluding people who have taken lipid-lowering medication. Participants with total cholesterol ≥240 mg/dL or high-density lipoprotein cholesterol <40 mg/dL or low-density lipoprotein cholesterol ≥160 mg/dL or triglycerides ≥200 mg/dL are defined as having dyslipidemia. Using the ocular surface disease index, we measured the DES severity and defined DES as an ocular surface disease index score ≥13. RESULTS:Men with dyslipidemia had an odds ratio of 1.29 (95% confidence interval, 0.97-1.71) for DES in an unadjusted model compared with those without DES. After adjusting for age, body mass index, hypertension, diabetes, occupations, smoking and drinking status, exercise, contact lens use, computer use, study cohorts, and calendar year of examinations, the adjusted odds ratio for DES was 1.40 (1.03-1.90) in men. However, there was no significant association between dyslipidemia and DES in women, even after stratifying by menopausal status. CONCLUSIONS:Our findings suggest that dyslipidemia may be associated with the prevalence of DES in Korean men, but not in women.

journal_name

Cornea

journal_title

Cornea

authors

Choi HR,Lee JH,Lee HK,Song JS,Kim HC

doi

10.1097/ICO.0000000000002133

subject

Has Abstract

pub_date

2020-02-01 00:00:00

pages

161-167

issue

2

eissn

0277-3740

issn

1536-4798

journal_volume

39

pub_type

杂志文章

相关文献

CORNEA文献大全
  • Amniotic membrane transplantation and fibrin glue in the management of corneal ulcers and perforations: a review of 33 cases.

    abstract:PURPOSE:To evaluate the efficacy of amniotic membrane in corneal ulcers refractive to conventional treatment and amniotic membrane with fibrin glue in corneal perforations. METHODS:Amniotic membrane transplantation (AMT) was performed in 33 eyes from 32 patients for corneal ulcers refractive to conventional treatment....

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000151547.08113.d1

    authors: Hick S,Demers PE,Brunette I,La C,Mabon M,Duchesne B

    更新日期:2005-05-01 00:00:00

  • Modified relaxing incision technique for postkeratoplasty astigmatism.

    abstract::A modified relaxing incision technique for postkeratoplasty astigmatism is described in this article. Following the initial, standard relaxing incision techniques, a planned spreading and recutting of the initial relaxing incision was performed at 1-3-week intervals following the initial surgery. The wound may be deep...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Forstot SL

    更新日期:1988-01-01 00:00:00

  • Correlation between tear film osmolarity, dry eye disease, and rheumatoid arthritis.

    abstract:PURPOSE:The aim of this study was to evaluate the reliability of tear film osmolarity as a diagnostic tool for detecting dry eye disease (DED) in patients with rheumatoid arthritis (RA). The second aim was to determine whether there is a relationship between tear film osmolarity, a commonly used RA score, and diagnosti...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000257

    authors: Schargus M,Wolf F,Tony HP,Meyer-Ter-Vehn T,Geerling G

    更新日期:2014-12-01 00:00:00

  • The fellow eye of patients with aphakic bullous keratopathy.

    abstract::The fellow normal-appearing eyes of 23 patients with unilateral aphakic bullous keratopathy were examined by wide-field specular microscopy and pachymetry. All patients had: pseudophakic or aphakic bullous keratopathy in one eye; unoperated fellow eye on no medication; no other ocular disease; and no endothelial gutta...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Roberts CW,Boruchoff SA,Kenyon KR

    更新日期:1984-01-01 00:00:00

  • Immunofluorescence of rabbit corneas after collagen cross-linking treatment with riboflavin and ultraviolet A.

    abstract:PURPOSE:To assess ultrastructural modifications in keratocytes and inflammatory cell response in rabbit corneas after riboflavin and ultraviolet A exposure using immunofluorescence microscopy. METHODS:Twenty adult New Zealand albino rabbits weighing 2.0–3.0 kg were used in this study. Two rabbits served as controls.Th...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181bdf1cc

    authors: Esquenazi S,He J,Li N,Bazan HE

    更新日期:2010-04-01 00:00:00

  • Can we measure corneal biomechanical changes after collagen cross-linking in eyes with keratoconus?--a pilot study.

    abstract:PURPOSE:To assess changes in biomechanical properties of human cornea after treatment of keratoconus with UV-A-riboflavin corneal collagen cross-linking (CXL). DESIGN:Single-center, prospective, interventional study. METHODS:Ten eyes of 10 patients aged 26.5 +/- 5.7 (mean +/- SD) years with progressive keratoconus we...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318190734d

    authors: Goldich Y,Barkana Y,Morad Y,Hartstein M,Avni I,Zadok D

    更新日期:2009-06-01 00:00:00

  • Coexistent congenital hereditary endothelial dystrophy and congenital glaucoma.

    abstract:PURPOSE:To retrospectively evaluate the coexistence of congenital glaucoma with congenital hereditary endothelial dystrophy. METHODS:Ten infants presented to our hospital with diffuse corneal edema and bilaterally elevated intraocular pressure (IOP). These patients were diagnosed with congenital glaucoma. All patients...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31804e4579

    authors: Ramamurthy B,Sachdeva V,Mandal AK,Vemuganti GK,Garg P,Sangwan VS

    更新日期:2007-07-01 00:00:00

  • Femtosecond laser-assisted superficial lamellar keratectomy for the treatment of superficial corneal leukomas.

    abstract:PURPOSE:To determine if superficial lamellar corneal excision with femtosecond laser followed by phototherapeutic keratectomy (PTK) using a masking substance improves visual acuity and optical quality of patients with severe corneal opacities. METHODS:Twelve eyes with corneal haze or scarring underwent confocal micros...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181eeb0c1

    authors: Alió JL,Agdeppa MC,Uceda-Montanes A

    更新日期:2011-03-01 00:00:00

  • Corneal subepithelial nodular scarring treated with phototherapeutic keratectomy in a child with Rothmund-Thomson syndrome.

    abstract:PURPOSE:To report the use of excimer laser phototherapeutic keratectomy (PTK) in the treatment of corneal subepithelial nodular scarring in a child with Rothmund-Thomson syndrome (RTS), a form of ectodermal dysplasia. METHODS:A case report and review of the literature. RESULTS:Excimer laser PTK successfully treated t...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200001000-00022

    authors: Stahl J,Fulcher S,Berkeley R

    更新日期:2000-01-01 00:00:00

  • Cyclosporine for Dry Eye Associated With Nivolumab: A Case Progressing to Corneal Perforation.

    abstract:PURPOSE:To present the clinical outcome of 2 cases of severe dry eye associated with Nivolumab, with 1 case progressing to corneal perforation. DESIGN:Case report. CASE 1:: A 58-year-old man with metastatic melanoma was referred for the management of severe bilateral dry eyes after undergoing his sixth cycle of Nivol...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000724

    authors: Nguyen AT,Elia M,Materin MA,Sznol M,Chow J

    更新日期:2016-03-01 00:00:00

  • Modified Ruiz procedure for reducing high astigmatism after penetrating keratoplasty.

    abstract:PURPOSE:To evaluate the refractive, keratometric, and visual outcomes of a modified Ruiz procedure in patients with high astigmatism after penetrating keratoplasty (PKP). METHODS:Retrospective cohort study with 26 eyes of 24 patients. A modified Ruiz incision pattern was used. Two paired arcuate incisions, centered on...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318153f241

    authors: Zuberbuhler B,Agrawal A,Gale R,Kipioti T,Gauba V,Noble B

    更新日期:2007-12-01 00:00:00

  • Diphosphonium ionic liquids as broad-spectrum antimicrobial agents.

    abstract:PURPOSE:One of the most disturbing trends in recent years is the growth of resistant strains of bacteria with the simultaneous dearth of new antimicrobial agents. Thus, new antimicrobial agents for the use on the ocular surface are needed. METHODS:We synthesized a variety of ionic liquid compounds, which possess 2 pos...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31823f0a86

    authors: O'Toole GA,Wathier M,Zegans ME,Shanks RM,Kowalski R,Grinstaff MW

    更新日期:2012-07-01 00:00:00

  • Inhibitory effects of tranilast on the proliferation and functions of human pterygium-derived fibroblasts.

    abstract:PURPOSE:We studied the possibility that tranilast, an antiallergic and antiproliferative drug, may be beneficial for the treatment of pterygium. METHODS:Pterygium-derived cells were identified by immunohistochemical methods. Growth rate of pterygium-derived cells was determined by using a hemocytometer. Chemotaxis was...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200005000-00021

    authors: Isaji M,Kikuchi S,Miyata H,Ajisawa Y,Araki-Inazawa K,Tsukamoto Y,Amano Y

    更新日期:2000-05-01 00:00:00

  • Immunohistochemical Study of SARS-CoV-2 Viral Entry Factors in the Cornea and Ocular Surface.

    abstract:PURPOSE:To confirm the ocular tropism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by evaluating the expression of viral entry factors in human ocular tissues using immunohistochemistry. METHODS:Fresh donor corneas and primary explant cultures of corneal, limbal, and conjunctival epithelial cells we...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002509

    authors: Roehrich H,Yuan C,Hou JH

    更新日期:2020-12-01 00:00:00

  • Deep anterior lamellar keratoplasty using the manual dissection technique of Melles: a histopathologic correlation.

    abstract:PURPOSE:To report the histopathologic findings in the host tissue of 2 human keratoconic corneas undergoing maximum-depth anterior lamellar keratoplasty (MDALK) using the manual dissection technique described by Melles. METHODS:Corneal buttons were examined from 2 patients with keratoconus who underwent MDALK using th...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000179930.97651.8f

    authors: Saw VP,Ng T,Crouch R,Maloof AJ

    更新日期:2006-09-01 00:00:00

  • Functional Morphology of the Lipid Layer of the Tear Film.

    abstract::Meibomian glands secrete the oily layer of the tear film, which prevents excessive evaporation of tear fluid. Dysfunction of meibomian glands is not only one of the causes of evaporative dry eye but also one of the main causes of entire dry eye. To understand the pathophysiology of meibomian gland dysfunction, it is i...

    journal_title:Cornea

    pub_type: 杂志文章,评审

    doi:10.1097/ICO.0000000000001367

    authors: Arita R,Fukuoka S,Morishige N

    更新日期:2017-11-01 00:00:00

  • Assessment of the Tear Meniscus Using Optical Coherence Tomography in Patients With Type 2 Diabetes Mellitus.

    abstract:PURPOSE:To analyze tear meniscus dimensions with Fourier domain-optical coherence tomography (FD-OCT) in patients with type 2 diabetes mellitus. METHODS:Patients with type 2 diabetes without diabetic retinopathy (DR) (n = 54), with nonproliferative DR (n = 45), with proliferative DR (PDR) (n = 25), and controls (n = 4...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000651

    authors: Baek J,Doh SH,Chung SK

    更新日期:2015-12-01 00:00:00

  • Management of Descemet Membrane Detachment After Forceps Birth Injury.

    abstract:PURPOSE:To describe the clinical signs of Descemet membrane (DM) detachment due to forceps-related birth injury and its subsequent management using optical coherence tomography. METHODS:Case report. RESULTS:A 3-day-old term infant presented with left eye corneal clouding and a definitive history of traumatic forceps-...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001147

    authors: Kancherla S,Shue A,Pathan MF,Sylvester CL,Nischal KK

    更新日期:2017-03-01 00:00:00

  • Cluster of Post-Operative Endophthalmitis Caused by Acanthamoeba T10 Genotype - A First Report.

    abstract:PURPOSE:To report a cluster of postoperative Acanthamoeba endophthalmitis after routine cataract surgeries. METHODS:A brief summary of sentinel events leading to the referral of 4 patients of postoperative endophthalmitis to our hospital is followed by clinical descriptions and the various diagnostic approaches and in...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002603

    authors: Rammohan R,Hajib Naraharirao M,Veerappan S,Vijayaraghavan P,Rajaraman R,Manayath GJ,Dsouza P,Radhakrishnan S,Venkatapathy N,Lakshmipathi D,Madhuravasal Krishnan J,Raghavan A

    更新日期:2021-02-01 00:00:00

  • Comparison of Tono-Pen AVIA intraocular pressure measurements performed at limbus with central corneal Tono-Pen AVIA intraocular pressure.

    abstract:PURPOSE:To compare Tono-Pen AVIA (TPA) intraocular pressure (IOP) measurements performed at the limbus with central corneal Tono-Pen AVIA (TPA) intraocular pressure. METHODS:Fifty-one patients attending our outpatient department with a best corrected visual acuity of ≥ 20/40, no corneal disease, and no astigmatism gre...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31827c9d25

    authors: Sharma R,Majumdar S,Sobti A,Arora T,Agarwal T,Dada T

    更新日期:2013-07-01 00:00:00

  • Descemet Membrane Endothelial Keratoplasty Patch for Persistent Corneal Hydrops.

    abstract:PURPOSE:To report successful management of a case of persistent keratoconus-related hydrops with a Descemet membrane endothelial keratoplasty (DMEK) patch graft. METHODS:A case of corneal hydrops persisting for 7 months treated with DMEK was identified. The following information was collected: demographic data, surgic...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001351

    authors: Tu EY

    更新日期:2017-12-01 00:00:00

  • The stability of corneal topography in the post-blink interval.

    abstract:PURPOSE:Videokeratoscopes provide a wealth of information about the topography of the ocular surface. Although there have been numerous studies of the accuracy and precision of videokeratoscopes with inanimate test objects, little information exists on their precision (repeatability) for real eyes. METHODS:To investig...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200111000-00010

    authors: Buehren T,Collins MJ,Iskander DR,Davis B,Lingelbach B

    更新日期:2001-11-01 00:00:00

  • Colorimetric indicators of microbial contamination in corneal preservation medium.

    abstract:PURPOSE:To compare acid-base and oxidation-reduction indicators and to investigate the effect of buffer and temperature on the colorimetric detection of microbial growth in corneal preservation media. METHODS:Corneal preservation media containing gentamicin, without or with HEPES buffer, were prepared with either phen...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200007000-00023

    authors: Chu YI,Penland RL,Wilhelmus KR

    更新日期:2000-07-01 00:00:00

  • Double-Line Reflection Pattern as a Simple Method to Determine Graft Orientation of Descemet Membrane Endothelial Keratoplasty.

    abstract:PURPOSE:To describe a simple finding, consisting of a double-line reflection from the graft inside the anterior chamber, that can be used to determine the correct donor tissue orientation in Descemet membrane endothelial keratoplasty: which we would like to call Berrospi's sign. METHODS:Evaluation of the presence of l...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001889

    authors: Berrospi RD,Galvis V,Bhogal M,Tello A

    更新日期:2019-06-01 00:00:00

  • Intraocular lens exchange 1 week after descemet stripping automated endothelial keratoplasty.

    abstract:PURPOSE:To report a case of intraocular lens (IOL) exchange performed 1 week after Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS:Describe the clinical findings and outcome of IOL exchange in an 80-year-old man with pseudophakic bullous keratopathy and retained Artisan (Ophtec BV, Groningen, th...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181a1669e

    authors: Lapenna L,Kadyan A,Busin M

    更新日期:2010-02-01 00:00:00

  • Transmission of rabies by corneal graft.

    abstract::Viruses such as human immunodeficiency virus, herpes simplex virus, cytomegalovirus, hepatitis B, hepatitis C, and rabies can be transmitted to the recipient by corneal transplantation. Very few cases of rabies have been reported. Here we report two cases of rabies transmitted by the same donor. Both of the recipients...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199607000-00014

    authors: Javadi MA,Fayaz A,Mirdehghan SA,Ainollahi B

    更新日期:1996-07-01 00:00:00

  • Brillouin Microscopy Visualizes Centralized Corneal Edema in Fuchs Endothelial Dystrophy.

    abstract:PURPOSE:To investigate the feasibility of using Brillouin microscopy for assessment of corneal edema in patients with Fuchs endothelial corneal dystrophy (FECD). Brillouin microscopy analyzes the frequency shift of light inelastically scattered by naturally occurring acoustic waves in a small volume of tissue. The resu...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002191

    authors: Eltony AM,Clouser F,Shao P,Pineda R 2nd,Yun SH

    更新日期:2020-02-01 00:00:00

  • Cyclosporine A Downregulates MMP-3 and MMP-13 Expression in Cultured Pterygium Fibroblasts.

    abstract:PURPOSE:To investigate the regulation of matrix metalloproteinase (MMP)-3 and MMP-13 expression over time and in the presence of cyclosporine A (CsA) in primary cultured human pterygium fibroblasts. We also examined the effects of CsA on cultured human pterygium fibroblasts. METHODS:Primary cultured human pterygium fi...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000477

    authors: Kim YH,Jung JC,Jung SY,Kim YI,Lee KW,Park YJ

    更新日期:2015-09-01 00:00:00

  • Very low risk of light-induced retinal damage during Boston keratoprosthesis surgery: a rabbit study.

    abstract:PURPOSE:The aim of this study was to assess the possibility of light damage to the retina by a surgical microscope during implantation of a Boston Keratoprosthesis (B-KPro) in rabbits. METHODS:The retinal irradiance from a Zeiss OPMI Lumera S7 operating microscope was measured at the working distance (16.5 cm). Light ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000029

    authors: Salvador-Culla B,Behlau I,Sayegh RR,Stacy RC,Dohlman CH,Delori F

    更新日期:2014-02-01 00:00:00

  • Unusual presentation of paraproteinemic corneal infiltrates.

    abstract::A 76-year-old man with bilateral corneal infiltrates secondary to a monoclonal gammopathy of undetermined significance (MGUS) is described. The corneal changes simulated a remote lattice dystrophy. Although the clinical presentation of corneal opacities secondary to paraproteinemic conditions is somewhat variable, thi...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Spiegel P,Grossniklaus HE,Reinhart WJ,Thomas RH

    更新日期:1990-01-01 00:00:00