Abstract:
PURPOSE:To report the first use of Descemet stripping automated endothelial keratoplasty (DSAEK) for spontaneous Descemet membrane detachment in a patient with osteogenesis imperfecta (OI), keratoconus, and acute bullous keratopathy. METHODS:A case report of a 25-year-old man with OI and symptomatic unilateral bullous keratopathy secondary to spontaneous Descemet membrane detachment is described. The patient presented with acute loss of vision in his right eye and was noted on slit-lamp examination to have a totally detached and taut Descemet membrane, spanning the anterior chamber. This diagnosis was confirmed with an anterior segment OCT (Visante; Carl Zeiss Meditec, Dublin, CA). RESULTS:After an attempt to reattach the Descemet membrane with air bubbling was unsuccessful, the patient underwent successful DSAEK. Seven months postoperatively, his best spectacle-corrected visual acuity was 20/50 compared with his other eye, which was 20/40. There were some central folds in the donor noted immediately postoperatively that have persisted. CONCLUSIONS:To the best of our knowledge, this case is the first documented spontaneous Descemet membrane detachment in a patient with OI and probable keratoconus treated successfully with DSAEK. Unlike in classical keratoconus hydrops, medical management is unlikely to resolve a total Descemet membrane detachment. This unusual Descemet membrane detachment was tightly stretched across the anterior chamber without any obvious tear, making simple air or gas bubble apposition impossible. Attempts to tear the Descemet membrane and then bubble led to significant folds. DSAEK was successful in removing the detached Descemet membrane and replacing it with the donor tissue.
journal_name
Corneajournal_title
Corneaauthors
Gorovoy MS,Gorovoy IR,Ullman S,Gorovoy JBdoi
10.1097/ICO.0b013e318225418bsubject
Has Abstractpub_date
2012-07-01 00:00:00pages
832-5issue
7eissn
0277-3740issn
1536-4798journal_volume
31pub_type
杂志文章相关文献
CORNEA文献大全abstract:PURPOSE:To assess the influence of donor characteristics on the outcome of anterior lamellar keratoplasty (ALK) and to evaluate whether corneal donor tissue considered unsuitable for penetrating or posterior lamellar keratoplasty due to poor endothelial condition may be safely used for ALK. METHODS:Institutional setti...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318285c8b4
更新日期:2013-08-01 00:00:00
abstract:PURPOSE:To report 7 cases of recurrent corneal neovascularization (NV) and lipid deposition after subconjunctival injection of bevacizumab for the treatment of corneal NV-induced lipid keratopathy. METHODS:We conducted a prospective interventional case series that included 20 eyes of chronic lipid keratopathy that rec...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31825ec407
更新日期:2013-11-01 00:00:00
abstract:PURPOSE:To describe a novel use of conjunctival autograft in the management of surgically induced scleral necrosis that occurred after squint surgery. METHODS:Interventional case report. RESULTS:A 22-year-old man underwent bilateral adjustable squint surgery. Two weeks postoperatively, he developed conjunctival retra...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3181b532e5
更新日期:2010-05-01 00:00:00
abstract:PURPOSE:To report a case series of eyes with posterior polymorphous corneal dystrophy and steep nonkeratoconic corneas. METHODS:Retrospective, descriptive, nonrandomized case series. RESULTS:Thirty-five eyes of 18 patients (14 cases from 6 families and 4 isolated cases) with diffuse posterior polymorphous corneal dys...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3182114452
更新日期:2011-10-01 00:00:00
abstract:PURPOSE:To describe the outcomes of Descemet membrane endothelial keratoplasty (DMEK) performed in amblyopic aged (younger than 8 years) children. METHODS:This is a single-center retrospective study, including 11 eyes (7 congenital hereditary endothelial dystrophy and 4 congenital glaucoma) of 6 children in amblyopic ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002540
更新日期:2020-09-16 00:00:00
abstract:PURPOSE:To provide 6-month results of a 1-year clinical trial evaluating conductive keratoplasty (CK) for the treatment of presbyopic symptoms in emmetropic and hyperopic eyes. METHODS:A total of 143 patients with presbyopic symptoms were enrolled in this 1-year United States FDA clinical trial and treated to improve ...
journal_title:Cornea
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1097/01.ico.0000126321.13143.a0
更新日期:2004-10-01 00:00:00
abstract:PURPOSE:To determine the benefit of bilateral penetrating keratoplasty with regard to binocular vision. METHODS:We compared patients who underwent corneal transplantation bilaterally with patients who had successful corneal transplantation in one eye and corneal disease in the other eye. Specifically, changes in fusio...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200107000-00006
更新日期:2001-07-01 00:00:00
abstract::Mesenchymal stem cells isolated from connective tissues are pluripotent and differentiate into phenotypes of connective tissue cell lineages (osteoblasts, chondrocytes, and adipocytes) in vitro and in vivo. They have been used to treat mouse models of connective tissue disease such as lumican-null (Lum) and mucopolysa...
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/ICO.0000000000001010
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:To report a case of insect corneal foreign body with in vivo confocal microscopy performed. METHODS:Clinical presentation, clinical pictures, and treatment are discussed. Confocal microscopy of the injured cornea was performed in areas showing foreign bodies with and without infiltrations seen under the slit-l...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-200301000-00013
更新日期:2003-01-01 00:00:00
abstract:PURPOSE:To assess changes in biomechanical properties of human cornea after treatment of keratoconus with UV-A-riboflavin corneal collagen cross-linking (CXL). DESIGN:Single-center, prospective, interventional study. METHODS:Ten eyes of 10 patients aged 26.5 +/- 5.7 (mean +/- SD) years with progressive keratoconus we...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318190734d
更新日期:2009-06-01 00:00:00
abstract:PURPOSE:To investigate the changes in anterior and posterior corneal irregularity after Descemet membrane endothelial keratoplasty (DMEK). METHODS:This retrospective study included 27 eyes of 23 patients who underwent DMEK and 27 eyes of age-matched healthy controls. Corneal irregularity indexes, surface regularity of...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001722
更新日期:2018-11-01 00:00:00
abstract::The action of hydrogen peroxide on soluble proteins of the rat cornea has been evaluated. Two major corneal proteins are found to be oxidized by 10 mM hydrogen peroxide. Protein sequence and antibody recognition has shown one of the proteins to be albumin. Treatment of pure rat or human albumin with hydrogen peroxide ...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199211000-00014
更新日期:1992-11-01 00:00:00
abstract:PURPOSE:To report 5-year outcomes for graft survival and endothelial cell survival after Descemet stripping endothelial keratoplasty (DSEK) including regression modeling for cell survival over time. METHODS:This is a single-institution, retrospective, consecutive interventional series of 210 primary DSEK grafts operat...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001177
更新日期:2017-05-01 00:00:00
abstract:PURPOSE:To analyze factors implicating the association of ReNu with MoistureLoc (ReNu ML) multipurpose contact lens solution (MPS) with the increased incidence of Fusarium keratitis. METHODS:Used contact lens cases with and without contact lenses and MPS containers were collected from patients with confirmed or possib...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e31802dd3a4
更新日期:2006-12-01 00:00:00
abstract::An 81-year-old man with metastatic prostate carcinoma underwent a penetrating keratoplasty for phlyctenular keratitis. Two years later he developed a fleshy, vascular mass in the superotemporal corneal graft wound, at the site of prior graft sutures. An excisional biopsy of the mass was performed to rule out metastati...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/00003226-199211000-00019
更新日期:1992-11-01 00:00:00
abstract::Epithelium plays a very important structural and functional role in the cornea and conjunctiva. Evaluation of the epithelium is the first step in diagnosing many pathologic states. We have developed a new technique for the in vivo staining of nuclei of corneal and conjunctival epithelium in rabbits and guinea pigs. Se...
journal_title:Cornea
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract:PURPOSE:To evaluate the refractive, keratometric, and visual outcomes of a modified Ruiz procedure in patients with high astigmatism after penetrating keratoplasty (PKP). METHODS:Retrospective cohort study with 26 eyes of 24 patients. A modified Ruiz incision pattern was used. Two paired arcuate incisions, centered on...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318153f241
更新日期:2007-12-01 00:00:00
abstract:PURPOSE:To assess the endothelial cell loss after cataract extraction using a fluid-based system and compare it with conventional ultrasound. METHODS:A total of 46 eyes of 23 patients with up to 3+ bilateral cataract were included. The first eye was randomized to either fluid-based system or conventional ultrasound, a...
journal_title:Cornea
pub_type: 杂志文章,随机对照试验
doi:10.1097/01.ico.0000226366.64796.20
更新日期:2006-10-01 00:00:00
abstract:PURPOSE:To identify and assess the quality of questionnaires used to measure quality of life in keratoconus and guide selection of the most appropriate questionnaire for evaluating the impact of keratoconus. METHODS:A literature search was carried out in Scopus, Web of Science, PubMed, MEDLINE, Cochrane, and PsycINFO ...
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/ICO.0000000000002170
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:To describe the technique and outcomes of limbal stem cell-sparing lamellar keratoplasty (LSCS-LKP) for the management of advanced keratoglobus (KGB). METHODS:In a sequential interventional case series from March 2010 to December 2012, 8 eyes of 6 patients with advanced KGB underwent an LSCS-LKP. Three patient...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e3182a9b1ac
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:To report clinical, in vivo confocal microscopy and ex vivo histopathologic findings of Salzmann nodular degeneration (SND). METHODS:A 48-year-old woman with symptoms of ocular irritation and decreased visual acuity caused by SND in both eyes was treated by corneal scraping and phototherapeutic keratectomy (PT...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000214215.75496.a5
更新日期:2006-07-01 00:00:00
abstract:PURPOSE:To examine the tissue samples of 2 corneal recipients from a rabies-infected donor for the presence of rabies to explain their survival. METHODS:Interventional case series with a review of the literature. The explanted corneal donor buttons were examined via nested reverse transcriptase polymerase chain reacti...
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/ICO.0b013e3181e4572a
更新日期:2011-02-01 00:00:00
abstract:PURPOSE:In the late 1960s, the management of fungal keratitis was a serious unresolved problem. Little was known of the epidemiology of the disease, and there were no antifungal agents formulated for use in the eye. METHODS:A thorough review of the literature was done back to 1969 on clinical reports and experimental ...
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/00003226-200009000-00013
更新日期:2000-09-01 00:00:00
abstract:PURPOSE:This review discusses cellular senescence, the state in which normal cells do not respond to growth stimuli, and shows characteristic alterations in their cytologic and biochemical properties and their gene expression profiles. METHODS AND RESULTS:Cellular senescence is elicited by various stresses. It was rec...
journal_title:Cornea
pub_type: 杂志文章,评审
doi:10.1097/01.ico.0000247206.47897.92
更新日期:2006-12-01 00:00:00
abstract:PURPOSE:Posterior amorphous corneal dystrophy (PACD) is a rare disorder characterized by sheet-like opacification of the posterior corneal stroma, corneal thinning, and decreased corneal curvature. It is not known to be associated with progressive corneal ectasia. In this report, we examine the course of a patient with...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000001304
更新日期:2017-12-01 00:00:00
abstract:PURPOSE:To establish a time-proven "gold standard" in modified osteoodontokeratoprosthesis (OOKP) surgery. METHODS:The OOKP is the procedure of choice for restoring sight in patients with corneal blindness caused by end-stage ocular surface disease not amenable to penetrating keratoplasty. Members of the OOKP Study Gr...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/01.ico.0000157401.81408.62
更新日期:2005-11-01 00:00:00
abstract:PURPOSE:Ocular injuries after exposure to the vesicant sulfur mustard (SM) are characterized by acute corneal erosions and inflammation of the anterior segment that may be followed by delayed limbal stem cell deficiency (LSCD), expressed clinically by corneal neovascularization and epithelial defects. The present study...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0b013e318262e885
更新日期:2013-04-01 00:00:00
abstract:PURPOSE:To describe the varied presentations of posterior keratoconus. METHODS:This is a 3-year institute-based retrospective study report from June 2015 to June 2018 that describes 13 eyes of 12 patients with varied presentations of posterior keratoconus, evaluating tomographic changes using Scheimpflug corneal tomog...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000002455
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:Evaluation of efficacy of autologous platelet-rich plasma eyedrops as an adjunct to standard medical treatment as compared with standard medical treatment with artificial tears in acute ocular chemical injury. METHODS:Twenty eyes with grade III to grade V chemical injury were randomly assigned to 2 groups. Gro...
journal_title:Cornea
pub_type: 杂志文章,随机对照试验
doi:10.1097/ICO.0b013e3182114661
更新日期:2012-09-01 00:00:00
abstract:PURPOSE:To evaluate if donor corneas obtained from deaths occurring because of septicemia can be used for corneal transplantation. STUDY DESIGN:Prospective study. METHODS:Eleven septicemic donor corneas were used in the study and 10 donor corneas from deaths because of causes other than septicemia were used as contro...
journal_title:Cornea
pub_type: 杂志文章
doi:10.1097/ICO.0000000000000858
更新日期:2016-08-01 00:00:00